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Sébastien Poulin

@sebpoule.bsky.social
4.4K followers 1.3K following 1.5K posts

Medical microbiologist & Infectious diseases MD @ St-Jérôme & Montréal, Québec, 🇨🇦 🔝 Interests HBV HDV HIV & General I.D. French 🇨🇦 with a 💩 accent #IDsky #HIVsky #Medsky

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Sébastien Poulin @sebpoule.bsky.social · 22/09/2026
On this day, at the age of 42yo, Sept 22 2026, my last gas⛽️ 🚗 refill ever. Moving to electric car. Feels good.
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Sébastien Poulin @sebpoule.bsky.social · 20/09/2026
Pro tip; Stop using “reply all” email to confirm an abstract review if you didn’t change anything.
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Ilan Schwartz @germhuntermd.bsky.social · 17/09/2026
Less is more, ortho-ID edition Another game changer in ortho ID from the group that brought you OVIVA Pts with ortho infections who underwent curative surgery (no DAIR) with local implantation of abx were randomized to <=7d vs >=4w ABx No Dif in 12 mo relapse www.nejm.org/doi/full/10.... #IDSky
Forest plot with primary analysis results which shows no difference in definite treatment failure, definite/probable treatment failure, or definite/probable/possible treatment failure according to treatment durationForest plot showing subgroup analysis which shows no difference between shorter and longer duration antibiotics in any of the subgroups including prosthetic infection, Staph aureus mono infection, and whether local gentamicin was used in mono therapy or combination therapy
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 09/09/2026
🔥🔥Back online🔥🔥 IDSA/ESCMID 2026 Guidelines on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children Part-1 #idsky www.idsociety.org/practice-gui...
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Sébastien Poulin @sebpoule.bsky.social · 02/09/2026
Watching a @wrexhamafc.co.uk 3-0 win against Millwall (between cases at the 🏥) Go Reds Go !!! cc @josephmarcusid.medsky.social
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Jonathan Ryder, MD @jonathanrydermd.bsky.social · 29/08/2026
POET II RCT is out now in @nejm.org, assessing antibiotic duration in endocarditis! "Response-tailored" vs standard durations in Staph, Strep & Enterococci n=502 Response tailored with 13d less antibiotics, similar composite safety but higher relapse #IDSky www.nejm.org/doi/abs/10.1...
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IDSA @idsainfo.bsky.social · 22/08/2026
Meet the newest voices behind Let’s Talk ID! ID physicians @kcawcutt.bsky.social and @cortes-penfield.bsky.social join the podcast as co-hosts for episodes focused on research published in IDSA journals. (1/2)
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Clinical Infectious Diseases @cidjournal.bsky.social · 18/08/2026
HRA for you! HRA for you! HRA … not for you? ✅ Just Accepted ⭐ Editor's Choice 🔗 bit.ly/4wDbYls
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Sébastien Poulin @sebpoule.bsky.social · 13/08/2026
Have you ever seen a case of MRSL? Methicillin-Resistant Staphylococcus lugdunensis #IDsky n=1 yesterday for me 😵‍💫
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Sébastien Poulin @sebpoule.bsky.social · 02/08/2026
@wrexhamafc.co.uk ❤️
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 30/07/2026
🔥🔥IDSA AMR Guidance 2026🔥🔥 🔺Notable Updates from the 2024 IDSA AMR Guidance Document 🔺Meropenem dosing update: individualized dosing approach (1–2 g IV q8h) with higher doses considered in selected clinical scenarios. #idsky www.idsociety.org/practice-gui...
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Sébastien Poulin @sebpoule.bsky.social · 16/07/2026
A dream come true Visit of Wrexham 🏴󠁧󠁢󠁷󠁬󠁳󠁿 from 🇨🇦 @wrexhamafc.co.uk @vancityreynolds.bsky.social
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Sébastien Poulin @sebpoule.bsky.social · 14/07/2026
Source control > antibiotics since 1270 #NorthWalesTours #IDsky
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Sébastien Poulin @sebpoule.bsky.social · 10/07/2026
Walking in London #penicillin
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Sébastien Poulin @sebpoule.bsky.social · 08/07/2026
My best Strava activity so far
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Sébastien Poulin @sebpoule.bsky.social · 06/07/2026
👇
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Sébastien Poulin @sebpoule.bsky.social · 19/06/2026
Well, it finally happened. My first awkward Zoom moment. I was watching a pan-🇨🇦 post EASL meeting presentation (by CASL). I forgot to close my camera. I ended up bare chest while preparing a workout at home… in front of the « crowd » . 🤪😅🤦‍♂️🤷‍♂️
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Sébastien Poulin @sebpoule.bsky.social · 17/06/2026
and Benzylpenicillin versus flucloxacillin or cloxacillin for the treatment of penicillin-susceptible Staphylococcus aureus bacteraemia (SNAP): an international, multicentre, open-label, non-inferiority randomised controlled trial @thelancet.com #IDsky www.sciencedirect.com/science/arti...
sciencedirect.com
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 17/06/2026
🔥Just published 🔥NEJM SNAP RCT In patients with MSSA bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality and was associated with a lower incidence of acute kidney injury. #idsky www.nejm.org/doi/full/10....
nejm.org
Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia | NEJM
Staphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin should be preferred for the treatment of methicillin-susceptible S. aureus ...
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The Journal of Infectious Diseases @jidjournal.bsky.social · 10/06/2026
Concomitant liver steatosis in chronic HBV infection is linked to a distinct cytokine profile and reduced viral load ✅ Just Accepted 🔗 bit.ly/4ejsct3
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Sébastien Poulin @sebpoule.bsky.social · 09/06/2026
Important #HIV work by @frsimonetti.bsky.social and team. Here's a post by Dr Simonetti on LinkedIn👇 #IDsky ________________________________________ 🦀Time to celebrate🦀. Our study on #HIV non-suppressible viremia despite effective ART has been published in Nature Portfolio (Nat Comm).
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Sébastien Poulin @sebpoule.bsky.social · 07/06/2026
Cancelled; Studies of Oral Weekly Lepetegravir (Formerly GS-1720) and Lenacapavir Pacfosacil (Formerly GS-4182); WONDERS-1 and WONDERS-2 ⬇️CD4 I won’t lie; I completely missed that. #IDsky #HIVsky www.fiercebiotech.com/biotech/gile...
fiercebiotech.com
Gilead cancels midstage HIV trial as FDA’s clinical hold remains intact
After the FDA placed two of its next-gen HIV drugs on clinical hold last June, Gilead Sciences has now terminated one of the affected trials. | After the FDA placed two of its next-gen HIV drugs on cl...
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Sébastien Poulin @sebpoule.bsky.social · 29/05/2026
#EASL2026 «For the very first time in history, you saw a phase 3 trial with the endpoint S antigen (HBsAg) loss» -Dr @heinerwedemeyer.bsky.social about HBV B-Well phase 3 trials #IDsky
static.klipy.com
Lance Geiger: That Is History!
ALT: Lance Geiger: That Is History!
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Sébastien Poulin @sebpoule.bsky.social · 28/05/2026
HBV Functional cure with Bepirovirsen B-Well 1 and B-Well 2 phase 3 studies ➡️ 24 weeks of Bepi s/c q1 week (all on NUCs) ~19% if qHBsAg <3000 ~26% if qHBsAg <1000 #EASL2026 #IDsky
nejm.org
Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection | NEJM
Treatment with bepirovirsen, an antisense oligonucleotide targeting hepatitis B virus (HBV) transcripts, has the potential to result in a functional cure, defined by at least 24 weeks of a sustaine...
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 27/05/2026
🆕💥🔴Don’t Drop the B: Risk of Hepatitis B Virus Infection and Reactivation in the Era of Tenofovir-Sparing Regimens for Treatment and Prevention of HIV #idsky academic.oup.com/cid/article-...
academic.oup.com
Don’t Drop the B: Risk of Hepatitis B Virus Infection and Reactivation in the Era of Tenofovir-Sparing Regimens for Treatment and Prevention of HIV
Abstracts. Tenofovir-sparing antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) are increasingly used.
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Sébastien Poulin @sebpoule.bsky.social · 27/05/2026
Top 20 Greatest Hits in HIV Medicine; Thank you Dr @paulsaxmd.bsky.social for your great Montreal 🇨🇦 presentation (special bonus; picture of young Dr Sax and colleagues)
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Sébastien Poulin @sebpoule.bsky.social · 30/04/2026
Long time no see #IDsky Petechial hemorrhage in the palpebral conjunctiva of the lower eyelid … ❤️‍🩹Endocarditis (shared with patient consent)
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 20/04/2026
🔥Late Breakers PeterPen RCT prelim results challenges carbapenem default in ESBL BSI Pip/tazo vs MER (EI) ✅Non-inferior 7d failure(29.4% vs 33.5%) ❌No early mortality signal 30d mortality 14.4%(interim) 👉Will mortality follow?MERINO taught us the hard way! #ESCMIDGlobal2026 #IDsky
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 17/04/2026
▶️Optimising treatment of severe infections due to DTR organisms Bookmark this table, everyone's favorite table! #ESCMIDGlobal2026 #IDSky #EMIMCC
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Sébastien Poulin @sebpoule.bsky.social · 06/04/2026
New York - Library Way
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Paul Sax @paulsaxmd.bsky.social · 03/04/2026
One-month treatment for latent tuberculosis. Why aren't we using it? (Hint: We should.) voices.nejm.org/doi/full/10....
voices.nejm.org
One-Month Treatment for Latent Tuberculosis
Why aren’t we using it?
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Sébastien Poulin @sebpoule.bsky.social · 30/03/2026
Man from 🇭🇹 Unilateral scrotal swelling (+/- painless) To be continued #IDsky …
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Sébastien Poulin @sebpoule.bsky.social · 14/03/2026
Wow! What a game @wrexhamafc.co.uk ❤️❤️ Champagne !
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Sébastien Poulin @sebpoule.bsky.social · 07/03/2026
Wrexham vs Chelsea 5th round FA cup 1-0 1-1 (own goal) 2-1 2-2 2-3 (Red card Wrexham) 3-3 (off side) 2-4 final Honestly, f*** yes Wrexham ❤️❤️❤️ Now, let’s go back to Championship playoff race. 11 fixtures We are at position #6 Hull city (#5) Tuesday Swansea city (#14) Friday … Let’s go! #askwxm
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Sébastien Poulin @sebpoule.bsky.social · 04/03/2026
❤️ @wrexhamafc.co.uk
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Ilan Schwartz @germhuntermd.bsky.social · 03/03/2026
Omadacycline Monotherapy in NTM Pulmonary Disease Caused by Mycobacterium abscessus: Results From a Phase 2, Double-blind, Randomized, Placebo-controlled Study Compared to placebo, omadacycline monotherapy led to higher response rates Note: Lung Tx excluded academic.oup.com/cid/advance-... #IDSky
Visual abstract
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Sébastien Poulin @sebpoule.bsky.social · 02/03/2026
Madrid vacation with my family Wrexham ❤️ @wrexhamafc.co.uk #everytime #anywhere for Gab, 7 yo
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Jonathan Ryder, MD @jonathanrydermd.bsky.social · 01/03/2026
The just published TAPER-V trial has lots of fun journal club things to discuss: jamanetwork.com/journals/jam...
jamanetwork.com
Initial Vancomycin Taper for the Prevention of Recurrent C difficile Infection
This randomized clinical trial tested whether a 4-week pulse and taper vancomycin regimen was superior to a 2-week pulse regimen for preventing recurrence among patients with a first episode or first ...
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 27/02/2026
🔥Just published 🔥 TAPER-V RCT In this RCT of 256, a 4-week vancomycin pulse and taper regimen *had a probability of 74% to be superior to a standard 2-week pulse regimen in patients a first episode or first recurrence of CDI Vanco for 10d is obsolete! #IDSky #EMIMCC jamanetwork.com/journals/jam...
jamanetwork.com
Initial Vancomycin Taper for the Prevention of Recurrent C difficile Infection
This randomized clinical trial tested whether a 4-week pulse and taper vancomycin regimen was superior to a 2-week pulse regimen for preventing recurrence among patients with a first episode or first ...
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BK. Titanji @boghuma.bsky.social · 25/02/2026
Lenacapavir for PrEP was the big "star" of #CROI2026 after showing almost 100% effectiveness in preventing HIV in 2 large RCTs. Unfortunately at a pricing point of 28000$ a year it remains inaccessible to most. A drug is only as great as the number of people who can access and benefit from it.
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Liz Highleyman @lizhighleyman.bsky.social · 26/02/2026
That’s a wrap from #CROI2026. Until next year in hopefully warm & sunny San Diego! But my writing has only just begun — look for reports on @pozmagazine.bsky.social & @aidsmap.bsky.social in coming days.
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Sébastien Poulin @sebpoule.bsky.social · 26/02/2026
Meningococcal B (4CMenB) Vaccination for the Prevention of Gonorrhea in Men Who Have Sex With Men #CROI2026 credits @ hivvirology
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Sébastien Poulin @sebpoule.bsky.social · 26/02/2026
🤨Comparative Effectiveness of 3 Benzathine Penicillin G-Based Regimens in PWH With Early Syphilis #CROI2026 credits @ hivvirology
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Sébastien Poulin @sebpoule.bsky.social · 25/02/2026
Best place to follow #CROI2026 on social media👇 www.instagram.com/hivvirology/
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 16/02/2026
🔥Just published 🔥 ESCMID Clinical Guidelines on the Evaluation and Management of a Reported Antibiotic Allergy #IDSjy www.clinicalmicrobiologyandinfection.org/article/S119...
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BK. Titanji @boghuma.bsky.social · 08/02/2026
#IDSky I always email residents rotating with me survival tips for their time of the ID consult service. I like to keep this short and high yield but I am constantly editing and improving the tip sheet. What would you add or remove. It cannot be longer that one page 😊.
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Infected Terran @infectedterran.bsky.social · 06/02/2026
When I am declared God King Emperor, I am banning Cdiff PCR's
media.tenor.com
snoop dogg is wearing glasses and a red turtleneck sweater and says i said what i said
ALT: snoop dogg is wearing glasses and a red turtleneck sweater and says i said what i said
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Josh Davis @gurujosh.bsky.social · 05/02/2026
My top 10 ID papers for 2025. Full citations and descriptions available at clarityinitiative.org/hot-takes Also see/hear our Communicable podcast episode on this at communicable.transistor.fm/episodes/com... What were your top 10? Any thoughts about what I missed welcome! #IDSky #Top10papers
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Darcy Wooten (she/her) @darcy-id-doc.bsky.social · 03/02/2026
Grateful to have the opportunity to share this little piece of my heart. Love is always the answer. academic.oup.com/cid/advance-...
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