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Alf Soler-Bistué 🦠🔬🧫

@alfmicrobe.bsky.social
370 followers 609 following 68 posts

You may know @AlfMicrobioTweets from Twitter. PI at UNSAM 🇦🇷. Microbiology & genomics. Microbial, growth, chromosome structure & evolution. Vibrio, Bradyrhizobium (and Brucella) . ❤️🧪🦠Microbiology 🔬🧫❤️ Editor @ Curr. microbiology.

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Reposted by Alf Soler-Bistué 🦠🔬🧫
Jose M. Estevez @estevezjosem.bsky.social · 14/08/2026
Finally out!! Beatifull work leaded by Arezo Rahimi and Salma Balazadeh group at University of Göttingen and colaborators showing the power of root hairs induced by Flavo98 to enhance drought tolerence in plants!! www.nature.com/articles/s41...
nature.com
Endophytic Flavobacterium promotes root hair development and enhances drought tolerance via an ERF–CEP5 hormonal regulatory module - Nature Plants
Flavobacterium sp. 98 promotes root hair development and enhances plant drought tolerance via a novel signalling pathway, highlighting the role of plant–microorganism interactions for improving crop r...
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Aaron Sojourner @aaronsojourner.org · 25/07/2026
Admirable clarity @science.org
The Trump administration hates academic science funding, full stop. They hate where that money goes, and they hate who it goes to. They want to keep all that money for themselves, to hand out to favored cronies who can help them get elected and to steer yet more money and more power back into their hands.

That’s it. That’s the story
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Cees Dekker @ceesdekker.bsky.social · 22/07/2026
We built a a self-dividing synthetic cell ! Check out this #CDlab preprint on BioRxiv: www.biorxiv.org/content/10.6... Great work by 1st author Charu Sharma who encoded dynaminA in a genome and expressed that in liposomes that then divide into daughter cells! Collaboration with Koenderink lab!
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Noah Fierer @noahfierer.bsky.social · 19/06/2026
New preprint up: the power of protein language models - using a single gene (adenylate kinase) to predict the temperature optima of bacteria and bacterial communities from genomes or metagenomes www.biorxiv.org/content/10.6...
biorxiv.org
Predicting optimal growth temperatures of bacteria using learned structural information from a single protein
Temperature is a fundamental determinant of bacterial physiology and ecology. Optimal growth temperature (OGT) is highly variable across species, contributing to differences in where and when species ...
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 19/06/2026
The lab is crazy about the @fifaworldclub.bsky.social ! My collaborators improved the lab for the ocasion! @unsamoficial #microbiology #FifaWorldCup
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 01/06/2026
Huge Effort of @justinecollier.bsky.social Lab for understanding GcrA methylase role on cell cycle of a relevant alpha model: Agrobacterium. Papers such as this one guide us in our Bradyrhizobium research! Congrats to the team for a sound paper! www.biorxiv.org/content/10.6...
biorxiv.org
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 27/05/2026
"Function-specific epistasis shapes evolutionary trajectories towards antibiotic resistance". Huge parallel experimental evolution effort in E. coli under antimicrobial pressure by @gabypetrungaro.bsky.social at Bollenbach Lab at University of Cologne. doi.org/10.1101/2025...
doi.org
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Tatiana Fajardo @tatiana1979.bsky.social · 10/04/2026
'Botanica No.23' by Gail Potocki
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 07/04/2026
Huge work! Joint effort over four years of EPC Rocha & Fred Le Roux Labs sampling in the wild for 4 years! www.nature.com/articles/s41... @epcrocha.bsky.social @fredoleroux.bsky.social
nature.com
Complex temporal dynamics of phage-bacteria populations in an animal-associated marine system - Nature Communications
It remains unclear how viral genomes remain relatively stable over time, given the rapid co-evolution seen within hosts. Here, authors explore complex marine phage-bacteria dynamics using over 1000 ph...
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Nora Bär @norabar.bsky.social · 23/03/2026
¡Buen lunes! Hoy ⛈️ 23° de máx. La Tierra está crecientemente "fuera de equilibrio", según un reporte de la Organización Meteorológica Mundial, q preside la argentina Celeste Saulo @CelesteSau4049 👇Acabamos de vivir los 11 años más cálidos desde que se llevan registros www.nature.com/articles/d41...
nature.com
The world just lived through the 11 hottest years on record — what now?
Earth is increasingly ‘out of balance’, as more heat is trapped in the atmosphere, driving global warming.
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Pedro Dorado-Morales @doradomoralesp.bsky.social · 26/02/2026
New preprint out on bioRxiv! www.biorxiv.org/content/10.6... Can conjugative plasmids be used to control plasmid and pathogen spread? Follow me down the rabbit hole that led to this story 🧵
biorxiv.org
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 17/03/2026
bsky.app/profile/alfm... And its out at Nucleic Acids Research!! Cheers!
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 17/03/2026
Just published! at @narjournal.bsky.social . A new example of how gene order in bacterial genomes impacts cell physiology. Inthis episode we messed up with RNA polymerase genes! academic.oup.com/nar/article/...
academic.oup.com
Evolutionary constraints on RNA polymerase gene positioning in the genome of fast-growing bacteria
Abstract. How gene order along chromosomes affects cellular homeostasis and genome evolution remains poorly understood. Bacterial chromosomes are organized
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 25/02/2026
Celebrating Next paper by Larotonda et al. ! Really proud of our next work on positional Genetics of RNA polymerase. More news soon on this!!
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 08/01/2026
After 4 years of joint effort of my Lab and Dr. Llorente Team we took for first time SCRaMbLE to a bacterial system! This allowed us to massively reordered the main chromosome of Vibrio natriegens! biorxiv.org/content/10.6... Here's a 🧵
biorxiv.org
Creating bacterial genomic diversity through large-scale reconfigurations reveals phenotype robustness to organizational genome change
The ability to generate genomic diversity expands opportunities for understanding and engineering biology. Here, we demonstrate on-demand generation of diversity in bacterial genome configurations and...
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 01/11/2025
Old tools for new problems: how to get glyphosate resistant/degrading bacteria using Winogradsky columns... www.sciencedirect.com/science/arti...
sciencedirect.com
Materials-Based spatiotemporal analysis of microbial responses to glyphosate in Winogradsky columns
Glyphosate, the active ingredient in many broad-spectrum herbicides, is extensively used in agriculture but has come under increasing scrutiny due to …
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Aude Bernheim @audeber.bsky.social · 04/09/2025
Thanks to the authors of this piece. I love reading about the work of inspiring pioneers in bacterial genetics. Crazy amount of discoveries! Pioneer of bacterial genetics: the legacy of Esther Miriam Lederberg academic.oup.com/genetics/adv...
academic.oup.com
Pioneer of bacterial genetics: the legacy of Esther Miriam Lederberg
Abstract. Esther Miriam Lederberg's brilliant scientific lifework, from the discovery of phage lambda, bacterial conjugation, and replica plating, provided
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 21/08/2025
Super honored to have contributed to this excellent Reviews article by @val-meve.bsky.social and @amazeld.bsky.social on how extrachromosomal replicons (secondary chromosomes, chromids, megaplasmids) emerge in bacteria! 🦠 🧫 www.sciencedirect.com/science/arti...
sciencedirect.com
Taming wild replicons: evolution and domestication of large extrachromosomal replicons
Bacterial genomes often contain extrachromosomal replicons (ERs), ranging from small, mobile plasmids to large, stably inherited elements, such as meg…
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Nora Bär @norabar.bsky.social · 05/06/2025
Nuestros encuentros tempranos con bacterias son cruciales para el desarrollo de nuestro sistema inmunológico, muestra un estudio británico 👇 www.bbc.com/news/article...
bbc.com
Microbiome: First bacteria we meet can keep us out of hospital
For the first time, scientists show how our microbiome forms affects the risk of infection.
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 06/06/2025
Great paper on replication dynamics in E. coli with more than one oriC. What would happen if we further add more oriCs?? frontiersin.org/journals/mic... Congrats Ole Skovgaad for this sound paper!!
frontiersin.org
Frontiers | An additional replication origin causes cell cycle specific DNA replication fork speed
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Nora Bär @norabar.bsky.social · 05/06/2025
La intervención de @VLeviLab ayer, en el Senado. También im-per-di-ble 👇 www.youtube.com/watch?v=QgTU...
youtube.com
VALERIA LEVY - COMISIÓN DE CIENCIA Y TECNOLOGÍA 04-06-25
YouTube video by Senado Argentina
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Jose M. Estevez @estevezjosem.bsky.social · 05/06/2025
Here is our newest paper recently published in Plant Communications on "Root hair growth under the control of auxin under low temperature low nutrient environment". Comments and suggestions are more than welcome! Here the pdf www.cell.com/plant-commun... Leaded by Victoria Berdion Gabarain et al.
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STCmicrobeblog @stcmicrobeblog.bsky.social · 29/05/2025
schaechter.asmblog.org/schaechter/2... (sorry for being late with today's 𝘕𝘰𝘵𝘦𝘸𝘰𝘳𝘵𝘩𝘺. we are not "up, up and away" because of ascension day, we simply overslept 🤦‍♂️) #MicroSky
schaechter.asmblog.org
Gene Location Matters
Noteworthy — Bacterial genomes are not a laundry list of genes, but dynamic structures intimately connected with cellular function. As a result, natural selection has a heavy hand in shaping chromosom...
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Nora Bär @norabar.bsky.social · 28/05/2025
😍Un equipo de la UBA se ubicó entre los 5 mejores (de más de 100) en el mundial de “satélites enlatados”👇en la final del proyecto CanSat, organizado por la Universidad Nacional de México, con un satélite del tamaño de una lata que ellos mismos diseñaron y fabricaron 👇
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 29/05/2025
Budget cuts do not curb our enthusiasm! Ian lab meeting today on Bradyrhizobium cell physiology! #LabMeetinDay
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 26/05/2025
Estas en 3-4° año de biotecnología o carreras afines? Estamos buscando un/a estudiante de @unsamoficial.bsky.social para incorporar al laboratorio y presentar a una beca de entrenamiento de la CIC PBA! Te interesa? Vení a trabajar con nosotros!! #UNSAM #Biotecnologia !!
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 10/05/2025
What a huge story!!! Integrons are page resistance genes carriers!!! Not just silent " long term memory" geneyic structures!! Congrats two all the team!!
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 10/05/2025
Certainly a great place for a posdoctoral experience! Highly recommended!!!
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 10/05/2025
Huge story by @celineloot.bsky.social ! The chromosomal integrons are reservoirs of defense systems against Phages!
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Jose A Escudero @jaescudero.bsky.social · 08/05/2025
🧪 Finally out after peer review, our work showing that "Mobile #Integrons carry Phage Defense Systems" is now published in Science 🎉 Short 🧵 www.science.org/doi/10.1126/...
science.org
Mobile integrons encode phage defense systems
Integrons are bacterial genetic elements that capture, stockpile, and modulate the expression of genes encoded in integron cassettes. Mobile integrons (MIs) are borne on plasmids, acting as a vehicle ...
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 07/05/2025
Submitted! Fingers crossed!!
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Jose M. Estevez @estevezjosem.bsky.social · 02/05/2025
📢 III Curso Avanzado en Biología Molecular y Biotecnología Vegetal. 5 - 14 Mayo. Presencial, Universidad de Chile. Estudiantes de pregrado, doctorado, post-doc y técnicos. Clases con investigadores de primer nivel, últimas innovaciones en biotecnología vegetal. Empresas líderes en la industria.
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 15/04/2025
And its out! Last work of the lab: "Evolutionary Constraints on RNA Polymerase Gene Positioning in the Genome of Fast-Growing Bacteria." We show how the genomic location of RNA polymerase impacts cell physiology. www.biorxiv.org/cgi/content/...
biorxiv.org
Evolutionary Constraints on RNA Polymerase Gene Positioning in the Genome of Fast-Growing Bacteria..
The influence of gene order within the chromosome on cellular homeostasis and genome evolution remains unclear. Bacterial chromosomes are structured along the replication origin ( oriC )-terminus ( te...
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Nora Bär @norabar.bsky.social · 11/04/2025
Sin mucho para festejar en el Día Nacional del Investigador Científico. Según la Ley de Financiamiento de la Ciencia, aprobada por unanimidad, este año debía invertirse el 0,45% del PBI. En lugar de eso... 👇
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Martín Becerra @aracalacana.bsky.social · 10/04/2025
Hoy en la Argentina es el Día del/a investigador/a científico/a por el natalicio de Bernardo Houssay. Houssay fue Premio Nobel de Medicina y fundador del Conicet, del que fue su primer presidente. El Conicet hoy está siendo desmantelado por el gobierno unr.edu.ar/dia-nacional...
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 10/04/2025
I was waiting two years to see this out!! The genomic location of bacterial genes is not random!!! Congratulation on the authors (Martin Lercher and Team!). www.science.org/doi/10.1126/...
science.org
Most bacterial gene families are biased toward specific chromosomal positions
The arrangement of genes along bacterial chromosomes influences their expression through growth rate–dependent gene copy number changes during DNA replication. Although translation- and transcription-...
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Vaughn Cooper @vscooper.micropopbio.org · 10/04/2025
As new Editor in Chief of Evolution, Medicine, and Public Health, an OA society journal of ISEMPH, we welcome papers at the interface of evolution and medicine. I especially encourage studies in infection biology, broadly construed. We're a great and constructive journal! academic.oup.com/emph
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 20/03/2025
Gran Curso de Biología Vegetal en Chile! Coordina el gran @estevezjosem.bsky.social
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Yves Brun lab @brunlabcaulo.bsky.social · 12/03/2025
Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at @umontreal.ca and @mila-quebec.bsky.social. Apply to ML.Antibiotics@gmail.com. See lnkd.in/dVVk4N3s. #microsky
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Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 19/03/2025
Great Paper by @vslioy.bsky.social on genomic plasticity of salmonella pathogenicity islands: the link between chromosome 3D and their expression! Huge effort, great work! Here is the preprint! www.biorxiv.org/content/10.1...
biorxiv.org
Bacterial chromatin remodeling associated with transcription-induced domains at pathogenicity Islands
The nucleoid-associated protein H-NS is a bacterial xenogeneic silencer responsible for preventing costly expression of genes acquired through horizontal gene transfer. H-NS silences several Salmonell...
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Vaughn Cooper @vscooper.micropopbio.org · 07/03/2025
More #standupforscience in Pittsburgh from @aleciarokes.bsky.social @nanamikubota.bsky.social
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Ximena Chong @xchongc.bsky.social · 11/02/2025
A propósito del día de las niñas y mujeres en ciencia, pase y lea las biografías de científicas chilenas, destacadas en distintas áreas, recogidas por la BCN en esta tabla periódica. Un excelente trabajo de la gran Karem Olmedo…
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Lean, el inmortal ☄️ @leanelinmortal.bsky.social · 11/02/2025
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Nora Bär @norabar.bsky.social · 11/02/2025
¡Buen martes! Hoy 🌨️🌩️⛈️ 26 de máx. Cientificidio: si se cumple lo dispuesto en el Presupuesto 2025 y las expectativas de inflación, la inversión en ciencia nunca habrá sido tan baja: será la menor desde que empezó a medirse, en 1972👇 www.eldestapeweb.com/sociedad/pol...
eldestapeweb.com
La inversión en ciencia y tecnología caería este año a su mínimo histórico
Un trabajo del grupo EPC la estima en un 0,157% del PBI, el menor porcentaje desde que se mide, en 1972; en 2002 fue del 0,17%
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Nora Bär @norabar.bsky.social · 11/02/2025
En el "Día Internacional de la Mujer y la Niña en la Ciencia", fuerza y corazón a nuestras investigadoras, que se distinguen en el país, la región y el mundo. ¡Campeonas! 💖💝💖 🌹🌹 🌟
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Pablo Semán @pabloseman.bsky.social · 06/02/2025
Un sólo político opositor advirtió que en el discurso de Davos Milei incluyo a la educación pública entre los derechos que distorsionan el mercado. UNO SOLO.
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Pauli 🌻 @birrinchen.bsky.social · 07/02/2025
Si me entero que no van a esto y después siguen llorando por acá los bloqueo a todos
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