Reposted by Alecia Rokes
What influence does evolutionary history have on basal transcriptomes? On transcriptomic response to drug? On genetic paths for drug resistance? On fitness tradeoffs? Check out our latest preprint to find out!
By @aleciarokes.bsky.social @asantoslopez.bsky.social
www.biorxiv.org/content/10.1...
biorxiv.org
History shapes regulatory and evolutionary responses to tigecycline in strains of Acinetobacter baumannii from the pre- and post-antibiotic eras
Evolutionary history encompasses genetic and phenotypic bacterial differences, but the extent to which history influences drug response and antimicrobial resistance (AMR) adaptation is unclear. Histor...
