iiinova — where your digital self keeps evolving

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The Histochemical Society (HCS) and Journal (JHC) @histochemicalsoc.bsky.social · 12/06/2026

There's only a few days left to apply for the IHCIF Course at the Marine Biological Laboratory! Learn to design, validate & troubleshoot experiments with experts and real lab experience. 📅 Application due: June 16th 💸 Financial aid is available 🔗 hcs.memberclicks.net/ihcif-course

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Alejandro Adam @aleadam.bsky.social · 12/06/2026

Happy to share that we received a long awaited NOA for an MPI R01 with my fabulous colleague and friend @gabbyfredman.bsky.social to study how endothelial cells regulate atherosclerosis progression and stability and how we can leverage resolution mechanisms encoded by ECs to promote plaque stability

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Alejandro Adam @aleadam.bsky.social · 23/02/2026

Jenna Norton is absolutely right. Thank you for speaking up. @holdenthorp.bsky.social, as someone that grew under a military dictatorship, I can safely say that keeping your head down is not an effective act of resistance. As scientists, we do our work by keeping our head up and speaking the truth.

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Melissa Nadia Viviana 🐸 @resistrebelrevolt.net · 17/02/2026

😲 This is THE most amazing thing I've seen this year. (And that's saying something!) A ResistDance retelling of ICE murdering Renee Good & Alex Pretti enacted through dance‼️😭 Performed by First Amendment Troop in DC. 🤍

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Matthew Freeman @mjafreeman.bsky.social · 03/02/2026

I watched much of Ian Chapman's (Head of @ukri.org) appearance this morning at @ukparliament.parliament.uk Science, Innovation and Technology Committee.. A few points and new information that bioscientists may find interesting... A 🧵

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Maria Langholz @marialangholz.bsky.social · 26/01/2026

pretty wild statement re: Republican Chris Madel drop from race for MN governor: "Saying he cannot support the national GOP's 'stated retribution on citizens of our state, nor can I count myself a member of a party that would do so."

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NAVBO @navbo.bsky.social · 17/01/2026

NAVBO is joining the January 21st Day of Action to urge increased FY26 funding for medical research! 🧪🫀🔬 ✅ Join us: speak4.app/lp/6t01dslt/... #SupportCures #FundMedicalResearch #CuresCantWait

speak4.app

Make Your Voice Heard!

Both the House of Representatives and the Senate have advanced draft spending bills that maintain federal funding for lifesaving...

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Schmidt Ocean Institute @schmidtocean.bsky.social · 02/01/2026

ROV pilots filmed this giant phantom jelly, or Stygiomedusa gigantea, at 253 meters during an ROV descent to explore the Colorado-Rawson submarine canyon wall. #ArgentinianDeepSeeps

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NY-CURES @nycures.bsky.social · 31/12/2025

@governor.ny.gov we’re set on one goal in 2026: getting EBRI up & running so New Yorkers get the benefits ASAP after such a hard year for many. EBRI is a transformative investment bringing new medicines & money that can solve other priorities in education, healthcare, transport for the long term.

media.tenor.com

a cartoon of spongebob reading a piece of paper with the words my new year 's resolutions above him

ALT: a cartoon of spongebob reading a piece of paper with the words my new year 's resolutions above him

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Tony Ferrante @tonyferrante.bsky.social · 30/12/2025

As a doctor and scientist working to advance health, science, and economic growth in NY, I’m urging @governor.ny.gov to invest in the Empire Biomedical Research Institute to keep the state competitive, sustain jobs, and grow our life science economy. @gothamist.com reports: tinyurl.com/5fab5k7u

tinyurl.com

NY medical schools press Gov. Hochul to put up billions for scientific research

The request comes amid continuing uncertainty over federal funding, with research and thousands of jobs on the line.

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American Society for Investigative Pathobiology @asipath.bsky.social · 16/12/2025

Join us in Fort Myers to #connect, #share, and #learn from the leading #DiseaseResearchers at #Pathobiology2026! Submit your abstract and register to save by by January 20 pathobiology2026.asip.org #DiseaseMechanisms #ASIP2026 #CareerDevelopment #PathobiologyResearch

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Jeremy Berg @jeremymberg.bsky.social · 11/12/2025

I stumbled across the 300th Episode of South Park, SHOTS!!! One on the most funny/not funny things I have seen in a while. It is about vaccinations and concerns about vaccine hesitancy and that vaccinations cause people to become "artistic". www.youtube.com/watch?v=QZ40...

youtube.com

Cartmans Mum gets a shot

YouTube video by Cat Uploader

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Zohran Kwame Mamdani @zohrankmamdani.bsky.social · 02/12/2025

Last week, ICE arrested and separated a father and son after a routine check-in. Six-year-old Yuanxin had just enrolled in the first grade at an elementary school in Astoria. Now he's in custody, alone. ICE won't say where. This cruelty serves no one. It must end.

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Kate Starbird @katestarbird.bsky.social · 02/12/2025

My wife has been HIV+ for 34 years. She’s alive today b/c work of activists who destigmatized the virus, pushed medical science to adapt & find ways to treat it, & advocated for gov health programs that helped fund her care. The current U.S. regime may want to go back in time, but we won’t let them.

White background, red ribbon. Text says “World AIDS Day”.

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Harry Wallop @harrywallop.co.uk · 02/12/2025

Great culture can save lives. Literally. Amazing letter in today’s @thetimes.com about Tom Stoppard

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Paolo Crosetto @paolocrosetto.bsky.social · 30/11/2025

Since AI slop is again all over Scientific Reports, a thread on the economics of grey-zone publishing. Why does slop keep getting published? What does it mean for science? How can we stop this? Background readings: Understand the strain: tinyurl.com/2b6wxx5r Stop the drain: tinyurl.com/3jfscscy

An obviously AI-generated figure with AI slop and fake text all over it, recently published in Scientific Reports.

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Robert Reich @rbreich.bsky.social · 21/11/2025

Socialism is what they called public power. Socialism is what they called social security. Socialism is what they called the growth of free and independent labor organizations. Socialism is their name for almost anything that helps all the people. —Harry Truman, 1952

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c0nc0rdance @c0nc0rdance.bsky.social · 21/11/2025

This team are searching for new "Asgard archaea" to sequence. Let's talk about why these bacteria-like organisms are so fascinating, why they're named for Norse mythology, and why looking at them is unlocking a better understanding of our own genomes. Once considered a type of oddball bacteria🦠...

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Too Big to Fail @toobigtofail.bsky.social · 21/11/2025

So, I have read articles written by people who claim that the entire concept of modern medicine is bad, because "artificially" saving people's lives has put a stop to human evolution by letting genetically inferior people breed. Great that those folks are in charge of the CDC now.

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Alejandro Adam @aleadam.bsky.social · 17/11/2025

Congratulations Margarida Barroso @barroso8.bsky.social for receiving the Carpenter Ranch Award from @histochemicalsoc.bsky.social ! So well deserved!

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Rev. Dr. Michael Woolf @revdrmichaelwoolf.bsky.social · 15/11/2025

I wanted to share probably the most important sermon I’ve given and it’s while I’m being arrested. It’s torture pure and simple what happens at #Broadview. I’m ok, though I was thrown to the ground and choked with my pectoral cross. A review of the video shows I was peaceful - did I deserve this?

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The Transmitter @thetransmitter.bsky.social · 10/11/2025

Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao. #neuroskyence bit.ly/47MXYLH

bit.ly

Without monkeys, neuroscience has no future

Research in primate brains has been essential for the development of BCIs, ANNs. New funding and policy changes put future such advances at risk.

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The Onion @theonion.com · 10/11/2025

Chuck Schumer Helps Pull Democrats Back From Brink Of Courage

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Adam Kinzinger @adamkinzinger.substack.com · 10/11/2025

Dems. Snatching defeat from the jaws of victory

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Journal of Clinical Investigation @jci.org · 09/11/2025

Previously shared: Systemic shock can lead to vascular dysfunction and organ failure. This issue’s cover features work by Alejandro P. Adam @aleadam.bsky.social showing inflammatory cytokines drives endothelial stress via cytoplasmic DNA. www.jci.org/articles/vie...

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Ben Goult @bengoult.bsky.social · 31/10/2025

Vinculin is a simple adapter protein right? Wrong! That’s been the prevailing view for the 46 years since it was discovered. Here we provide a new paradigm and show that vinculin is a complex mechanosensor itself, containing 6 binary switch domains. www.science.org/doi/10.1126/...

science.org

The mechanical response of vinculin

Vinculin buffers force via dynamic domain unfolding/refolding under physiological load and lacks a stable head-tail lock.

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Alejandro Adam @aleadam.bsky.social · 04/11/2025

Here's a quick thread with pics summarizing the paper. Many thanks for all the hard work at Albany Med and by our collaborator Pilar Alcaide!

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Alejandro Adam @aleadam.bsky.social · 03/11/2025

Very proud of this work that is now out on JCI describing a new #signaling pathway downstream of the #cytokine IL-6 in the #endothelium with implications in #sepsis and #shock. Short thread with a summary coming later today. For now just enjoy that gorgeous image taken by my student Fatma Awadalla!

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JMCC Plus @jmccplus.bsky.social · 03/11/2025

New work from Daoud et al. shows that removal of YAP/TAZ from vascular smooth muscle cells triggers inflammation and immune activation- indicating these factors as essential in vascular health.#vascularbiology sciencedirect.com/science/arti... #CardioSky

sciencedirect.com

YAP/TAZ deletion in vascular smooth muscle cells mirrors atherosclerosis-associated transcriptional programs

The transcriptional co-activators YAP (YAP1) and TAZ (WWTR1) are central regulators of vascular smooth muscle cell (VSMC) phenotype and vascular homeo…

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josh farkas 💊 @pulmcrit.bsky.social · 29/10/2025

The BICAR-ICU-2 trial just dropped! RCT involving IV bicarb in metabolic acidosis among patients with mod-severe AKI Bicarb didn't affect mortality but it reduced the need for dialysis & risk of bacteremia VERY similar conclusions to BICAR-ICU-1 🧵 #1/ jamanetwork.com/journals/jam... #EMIMCC

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neuralstemcells.bsky.social @neuralstemcells.bsky.social · 24/10/2025

Stem cell research is opening new doors for treating age-related #MacularDegeneration (AMD), a leading cause of vision loss. Join our co-founders, Drs. Jeffrey Stern and Sally Temple on @BrightFocus Foundation's Macular Chat on Wed, Oct 29.

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Richard McElreath 🐈‍⬛ @rmcelreath.bsky.social · 23/10/2025

Monty Python understood p-hacking

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Rep. Paul Tonko @reppaultonko.bsky.social · 18/10/2025

Today, I’m joining millions of Americans participating in No Kings rallies across the nation to reject Trump’s corruption and cruelty – and to stand up for democracy. Read more in my latest newsletter, and visit nokings.org to find a rally near you: tonko.house.gov/news/email/s...

tonko.house.gov

Representative Paul D. Tonko

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The Histochemical Society (HCS) and Journal (JHC) @histochemicalsoc.bsky.social · 16/10/2025

New this month in JHC: "Expression of Glial Cell Line–derived Neurotrophic Factor and Its Receptors in Glioblastoma." Click to read: bit.ly/3L1NIHz #glioblastoma #immunohistochemistry #insituhybridization

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NY-CURES @nycures.bsky.social · 15/10/2025

Add your name ✍ at www.nycures.org so Albany sees 10,000 scientists calling for the future of biomedical research to be built right here in New York. Our first email to members goes out soon—introducing the statewide biomedical institute we’re proposing and how you can help power it forward.

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Alejandro Adam @aleadam.bsky.social · 06/10/2025

Impressive demonstration of how a leukocyte separates the two ECs to squeeze by. Time to update my TEM lecture slides!

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Max Kozlov @maxkozlov.bsky.social · 30/09/2025

Staff members at the NIH seem to have done the impossible: spend the agency's $48 billion budget. “Everyone has been rallying together to clean up the mess, but it’s a mess that did not need to be made,” an NIH program officer told me. www.nature.com/articles/d41...

nature.com

NIH races to spend its 2025 grant money — but fewer projects win funding

Despite political obstacles, officials are on track to disburse all of the research funds allocated to US biomedical behemoth.

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Alejandro Adam @aleadam.bsky.social · 29/09/2025

@gabbyfredman.bsky.social EPA+DHA may be considered as part of the management of patients with NYHA functional class II-IV HF, irrespective of etiology or LVEF.

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Stephan Huveneers @huveneerslab.bsky.social · 25/09/2025

New vascular seminars coming up @evborg.bsky.social

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The Onion @theonion.com · 24/09/2025

Trump Administration Attempts To Link Autism To Tylenol theonion.com/trump-administration-a…

“I guess it’s back to laudanum.”

Tre Duncan, Sauce Mixer

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BK. Titanji @boghuma.bsky.social · 08/09/2025

David Baltimore passed away this weekend. A pioneer of molecular virology who won the Nobel prize in medicine & physiology for his discovery of viral reverse transcriptase. This essay he wrote in 2018 reflecting of his 60yr career in science is a great read. www.annualreviews.org/content/jour...

annualreviews.org

Sixty Years of Discovery | Annual Reviews

Each of us is a story. Mine is a story of doing science for 60 years, and I am honored to be asked to tell it. Even though this autobiography was written for the Annual Review of Immunology, I have ch...

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European Commission @ec.europa.eu · 05/08/2025

Double the discovery, double the momentum 🚀 Europe doubles down on research competitiveness with a major boost to #HorizonEurope: €95.5 billion foreseen for 2021-2027 💰💰💰💰💰💰💰💰💰 €175 billion proposed for 2028-2034 💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰

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Igor Brodsky @brodskyigorlab.bsky.social · 27/08/2025

open.substack.com/pub/clauswil... this is very true and highly under appreciated. Not just for a PhD but any high level accomplishment.

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The Histochemical Society (HCS) and Journal (JHC) @histochemicalsoc.bsky.social · 25/08/2025

The Journal of Histochemistry and Cytochemistry, the Histochemical Society’s flagship journal for 70 years, is seeking manuscript submissions! To learn more & submit: journals.sagepub.com/author-instr... #callforpapers #histochemistry #immunohistochemistry #microscopy

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Journal of Clinical Investigation @jci.org · 10/08/2025

ICYMI: Vasculopathy occurs early in systemic sclerosis, but intervention strategies are lacking. Colin Jamora & team reveal ANGPTL2 as an inducer of vasculopathy that drives cutaneous fibrogenesis in mice—mirroring SSc—and present a therapeutic approach: UAS03. buff.ly/xNYvnRj

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Alejandro Adam @aleadam.bsky.social · 05/08/2025

Now the scientific method has about a 4% success rate 🧪🧅

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