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Anne Kühnel

@akuehnel.bsky.social
564 followers 590 following 12 posts

Neuroscientist working on computational psychiatry @neuromadlab in Bonn

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Reposted by Anne Kühnel
Max Planck Institute of Psychiatry @mpi-psychiatry.bsky.social · 01/10/2026
📆 And finally, on October 20th, we are welcoming Dr. Robert Ohlendorf from the @mpicybernetics.bsky.social! 🔗 No registration needed, all information here: www.psych.mpg.de/events/46470...
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Nils Kroemer @nbkroemer.bsky.social · 26/09/2026
How can we best use signals from the gut to treat motivational symptoms in depression? 📣 We are hiring new PhD students 🧠 Full ad (in German; at least B2 is required): karriereamukb.de/jobs/doktora...
karriereamukb.de
Doktorand*in/PhD Student*in (m/w/d) - Karriereamukb | Jobs & Karriere an der Uniklinik Bonn
In der Sektion für Medizinische Psychologie der Klinik und Poliklinik für Psychiatrie und Psychotherapie des Universitätsklinikums Bonn ist zum nächstmöglichen Zeitpunkt folgende Stelle in Teilzeit (6...
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Kira Höffler @kirahoeffler.bsky.social · 22/09/2026
very happy about this one 😊
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Madeleine Kördel @mkoerdel.bsky.social · 02/09/2026
I’m very happy to share our new preprint on how acute stress responses in the lab relate to stress experienced in everyday life: www.biorxiv.org/content/10.6...
biorxiv.org
Stronger brain responses to acute stress reflect greater everyday stress variability
Laboratory stress tasks are widely used to assess individual differences in acute stress reactivity, yet it remains unclear how these responses correspond to stress experienced in everyday life. Here,...
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Alex Pike @alexandrapike.bsky.social · 28/07/2026
New paper alert! In this paper we were interested to formally test some of the assumptions made by computational psychiatrists - assumptions about parameter recoverability, reliability and validity. www.cambridge.org/core/journal...
cambridge.org
The recoverability, reliability, and generalizability of reward processing parameters and relation to mental health symptoms | Psychological Medicine | Cambridge Core
The recoverability, reliability, and generalizability of reward processing parameters and relation to mental health symptoms - Volume 56
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dennis hernaus @dhernaus.bsky.social · 27/07/2026
Why do people stop pursuing goals they care about❓ Motivational deficits are among the most disabling symptoms, yet current treatments often have only modest effects. In @lillyt.bsky.social new paper, she asks if we're missing an important piece of the puzzle 🧠 #neuroscience #cogpsyc #psychscisky
nature.com
Arousal shapes motivation: an integrative framework for understanding motivational deficits - Translational Psychiatry
Translational Psychiatry - Arousal shapes motivation: an integrative framework for understanding motivational deficits
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Nico Schuck @nicoschuck.bsky.social · 25/07/2026
Excited to see this paper on learning about how to learn out in eLIFE, spearheaded by Jonas Simoens and the team from Ghent incl @sebraem.bsky.social @pieterverbeke.bsky.social and Tom Verguts)
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 21/07/2026
Limitations of pupil diameter as a proxy for modes of locus coeruleus activity www.biorxiv.org/content/10.64898/20…
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Luisa Kaluza @lhkal.bsky.social · 15/07/2026
Does the brain's response to non-invasive vagus nerve stimulation depend on the current state of the body? Our new paper suggests yes. www.sciencedirect.com/science/arti...
sciencedirect.com
Non-invasive vagus nerve stimulation modulates Pavlovian bias in a state-dependent manner
The vagus nerve transmits vital signals between organ systems of the body and the brain. Despite growing interest in non-invasive transcutaneous vagus…
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Alex Pike @alexandrapike.bsky.social · 26/06/2026
I was so pleased and proud to watch my 2nd year PhD students, Lisa Woodley + @holmyers.bsky.social present their work at our PGR conference yesterday. Oh, and @lucysta02475610.bsky.social submitted a grant, and @kellydonegan.bsky.social chaired the mental health session. What a day!
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hvansteenbergen.bsky.social @hvansteenbergen.bsky.social · 27/05/2026
1/ New paper alert! Stress often builds over time, but many scientific studies treat it as just an on/off thing. In this paper, we introduce the Leiden Stroop-like Stress Task (LSST): a new paradigm for inducing graded, mild-to-moderate stress in the lab. www.sciencedirect.com/science/arti...
sciencedirect.com
The Leiden Stroop-like Stress Task: A tool to reveal physiological dynamics using graded stress induction
Stress evokes a complex repertoire of psychological and physiological responses. This paper introduces the Leiden Stroop-like Stress Task (LSST), a pa…
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Stephanie Noble @sneuroble.bsky.social · 25/05/2026
So glad to finally share work years in the making! What started with fMRI effect size benchmarks ended up showing that conventional study planning detects ~half of expected brain effects, suggesting more distributed processes than the lit shows (+ new methods for mass univ effect/power estimation)
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Alex Shackman @ajshackman.bsky.social · 24/05/2026
claude and have figured out how to (a) critique papers, while auto-deploying methods checklists; (b) integrate our critiques (cos we each miss stuff the other catches); and (c) provide career-stage-calibrated feedback and suggestions for improvement. perfect for stress-testing lab manuscripts.
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Maria Meier @mariame.bsky.social · 22/05/2026
New #OpenAccess paper in European Child & Adolescent Psychiatry 📄 Childhood maltreatment (CM) increases the risk for lifelong mental illness - but which biological pathways are involved here? One prominent target put forward is inflammation. But what drives proinflammatory states? A paper🧵
rdcu.be
Redox dysregulation, inflammation and mental health in adults with high risk of childhood maltreatment
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Nathaniel Haines @natehaines.bsky.social · 20/05/2026
some big news! hBayesDM has now been fully ported to cmdstan/cmdstanr/cmdstanpy check out the PR below, or the changelog for an overview: PR: github.com/CCS-Lab/hBay... Changelog: ccs-lab.github.io/hBayesDM/new... stay tuned for some additional features coming soon, including covariate support 🤓
github.com
feature: hBayesDM version 2.0 by Nathaniel-Haines · Pull Request #182 · CCS-Lab/hBayesDM
hBayesDM 2.0 — modernize stack & toolchain Top-to-bottom refactor of both the R and Python packages onto current Stan tooling, plus the supporting work to keep behavior, docs, and CI in sync. H...
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Nils Kroemer @nbkroemer.bsky.social · 15/05/2026
If you have not seen our new paper yet, check out the final publication 🍪 👇
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Nils Kroemer @nbkroemer.bsky.social · 13/05/2026
This is us 🎈. The study was led by @corcerebrum.bsky.social and the @neuromadlab.bsky.social team.
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Corinna Schulz @corcerebrum.bsky.social · 12/05/2026
How can 🍪 help us understand anhedonia? What started as a small project is now (> 2 years after the preprint, with revision deadlines landing exactly during my move from Tübingen to Bonn and even during a monastery-based PhD retreat) finally out in Cell Rep Med 🔽🧵 www.cell.com/cell-reports...
cell.com
Blunted anticipation, but not consummation, of food rewards in depression
Schulz et al. show that anhedonia in depression, as measured by a scale often equated with loss of pleasure, reflects reduced anticipation of food rewards rather than impaired enjoyment itself. Linkin...
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Carmen Sandi @carmensandi10.bsky.social · 08/05/2026
Hiring! Please share! Two postdoctoral researchers at EPFL, Lausanne, to join an SNSF-funded project on stress, motivation, immersive VR, physiology, multimodal sensing and translational biomarkers. Details & applications: www.fens.org/careers/job-... www.fens.org/careers/job-...
fens.org
Postdoctoral Researcher in Multimodal Human Sensing and Advanced Behavioral Data Analysis - Federation of European Neuroscience Societies
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Stephen Turner @stephenturner.us · 03/05/2026
Free and open-source images, icons, and tools for creating scientific illustrations doi.org/10.59350/5zt... 🧪
doi.org
Free and open-source images, icons, and tools for creating scientific illustrations
Phylopic, NIH Bioart, Bioicons, Scidraw, Open Science Art, Health Icons, Servier Medical Art, Biodiversity Heritage Library, the Noun Project, Segment Anything, Excalidraw, draw.io, Biographics
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Lukas Gunschera @lukasgunschera.com · 30/04/2026
🚨 Does social media use show established neurocognitive signatures of addiction? Concerns about social media addiction are widespread, yet whether platforms' design features actually engage the same neurocognitive pathways as established addictions has remained untested. doi.org/10.31234/osf...
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Alex Pike @alexandrapike.bsky.social · 29/04/2026
So exciting to see @lucysta02475610.bsky.social present the results of her mammoth, multi-year project to develop a questionnaire measuring the Negative Appraisal of Gastric Sensations (NAGS): it differentiates between people with eating disorders and gastric disorders! @yorkpsychology.bsky.social
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Global Stress and Resilience Network (GSRNet) @gsrnet.bsky.social · 29/04/2026
📣 Join us for the next GSRNet Flagship Webinar with Brenda Penninx, chaired by @dequervain.bsky.social Don't miss this opportunity to explore current perspectives on measuring stress in daily life! 📅 June 10, 2026 🕒 3pm CEST / 9am EDT / 6.30pm IST 🔗 gsr-net.org/workshops-we... #GSRNet #stress
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Huw Jarvis @huwjarvis.net · 27/04/2026
📄NEW PAPER📄 Dopamine underpins both effort💪 and reward learning⭐. Here, we show it also supports their interaction! w A Huynh, D Obawede, J Coxon @coxon.bsky.social, M Bellgrove, and T Chong @trevorchong.bsky.social #dopamine #learning #effort @plosbiology.org journals.plos.org/plosbiology/... 1/5
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yuzhu194.bsky.social @yuzhu194.bsky.social · 01/12/2025
Excited to share our new Nature Methods paper on DeepCor, a contrastive autoencoder for denoising fMRI. DeepCor separates neural signal from noise at the voxel level, works for single participants, and outperforms CompCor by up to 215% on real data. 1/7 doi.org/10.1038/s415...
doi.org
DeepCor: denoising fMRI data with contrastive autoencoders - Nature Methods
DeepCor is a deep-learning-based denoising approach for task-based and resting-state fMRI data that can be used even for single participants.
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Jeremiah Cohen @jeremiahycohen.bsky.social · 13/04/2026
Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1
biorxiv.org
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Hannah R Snyder @hannahrsnyder.bsky.social · 09/04/2026
New paper lead by my fab grad student Quynh Nguyen (who is on the postdoc job market btw) 🧵https://link.springer.com/article/10.1007/s11031-026-10226-5?utm_source=rct_congratemailt&utm_medium=email&utm_campaign=oa_20260408&utm_content=10.1007%2Fs11031-026-10226-5
link.springer.com
Blunted anticipatory pleasure, but not consummatory pleasure, is longitudinally linked to depression symptoms in college students - Motivation and Emotion
Motivation and Emotion - Blunted anticipatory and consummatory pleasure has been linked to depression symptoms, particularly anhedonic depression. The current study (1) investigated whether such...
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Nils Kroemer @nbkroemer.bsky.social · 28/03/2026
Can your brain's white matter proxies of inflammation re-identify you like a fingerprint? Turns out: yes, and we used this to psychometrically evaluate diffusion basis spectrum imaging and to detect depression-related changes in the cingulate bundle. #neuroskyence 🩺 www.medrxiv.org/content/10.6...
Participants with major depressive disorder (MDD) show lower fiber fraction and higher hindered fraction in the cingulum bundle. We observed differences in the cingulum bundle with decreased fiber fraction (tmax=4.68, k=38, pFWE<.001), indicating reduced axonal integrity (left) and increased hindered fraction (tmax=4.74, k=32, pFWE<.001), suggesting edema (right) in participants with MDD vs. healthy control participants (HCP). These changes indicate increased white matter inflammation in participants with MDD. In voxels showing differences between HCP and MDD groups, the reliability of fiber fraction and hindered fraction was high (lower insets).
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Karin Roelofs @epanlab.bsky.social · 25/03/2026
Super proud of @sjoerdmeijer.bsky.social who demonstrated that amygdala-TUS slows initial threat acquisition and enhances subsequent extinction. Great collaboration with @lennartverhagen.bsky.social and @deVoogdld.bsky.social ea. Thanks to @ERC.europa.eu. www.science.org/doi/10.1126/...
science.org
The human amygdala in threat learning and extinction
Ultrasonic neuromodulation of the human amygdala provides causal evidence for its role in forming persistent threat memories.
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Nils Kroemer @nbkroemer.bsky.social · 16/03/2026
A teaser for our upcoming preprint on the short-term test-retest reliability of diffusion basis spectrum imaging. Voxel-level reliability of hindered fraction (a proxy measure of edema) in white matter is good, particularly close to cortical gray matter. W/ @lhkal.bsky.social @akuehnel.bsky.social
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Nils Kroemer @nbkroemer.bsky.social · 09/03/2026
I am enjoying a few uninterrupted hours of plotting today. Finally got my hands on our diffusion basis spectrum imaging data, and it looks good, particularly in white matter voxels. I hope we will have a preprint coming out in a few weeks, led by @lhkal.bsky.social & @akuehnel.bsky.social
Sneak peek of an inset of the results figures from our diffusion basis spectrum imaging data.
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Vanessa Teckentrup @glassybrain.bsky.social · 23/02/2026
Thoroughly enjoyed writing a commentary on a great paper by @hugofleming.bsky.social et al for @biologicalpsych.bsky.social:GOS, focusing on how to further explore metabolic contributions to learning and feeling using real-time data and interventional designs: www.sciencedirect.com/science/arti...
sciencedirect.com
Metabolic Contributions to Learning and Feeling: Why They Matter and How to Make the Most of Them
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Vanessa Teckentrup @glassybrain.bsky.social · 23/02/2026
Thanks to Deanna Barch for the opportunity to write this and @akuehnel.bsky.social for her thoughts on the first draft! And check out @hugofleming.bsky.social's paper for an exciting blend of computational psychiatry & real-time metabolic monitoring: www.sciencedirect.com/science/arti...
sciencedirect.com
Metabolism and the Mind: Investigating the Link Between Glucose Control and Reinforcement Learning in Humans
Signals from the body profoundly influence cognition. This process is known as interoception, and has been extensively studied in the cardiac, respira…
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Nils Kroemer @nbkroemer.bsky.social · 04/02/2026
Pupil dilation is an established biomarker of arousal, and studies have shown that non-invasive vagus nerve stimulation (taVNS) elicits pupil dilation. Here, we find that it depends on sensory matching. #neuroskyence 🩺 Now published in @cp-iscience.bsky.social www.cell.com/iscience/ful...
cell.com
Effects of non-invasive vagus nerve stimulation on pupil dilation are dependent on sensory matching
Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising tool to modulate motivation and affect, with prior studies showing greater pupil dilation compared to sham. However, sensory dif...
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Maria Meier @mariame.bsky.social · 03/02/2026
Diese Woche berichtet @glassybrain.bsky.social u.a. vom Vagus und von vielen anderen spannenden Neuroscience Themen auf @realscientists.de ! Schaut mal vorbei 🔥
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Natalie Schaworonkow @nschawor.bsky.social · 16/01/2026
main goal for this year: find a new job! 🙂 looking for a role with fun & complex technical challenges & within a great community. my main expertise is in signal processing/EEG/MEG, but topic-wise I am quite flexible. science/industry both great! starting mid-year. nschawor.github.io/cv
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Adam Kucharski @adamjkucharski.bsky.social · 13/01/2026
Want to get the data out of a PDF figure? As in, the actual data – not a rough trace-along-the-lines version? I made an app you might like: adamkucharski.github.io/pdf2plot/ It all started a few years ago... 🧵
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Zsofia Karlocai @kzsofia.bsky.social · 13/01/2026
📣 Happy to share that our paper with Johan Vegelius is published! Title: “Developmental differences in reward-learning and its connection to resting-state functional connectivity modeled using a hierarchical Bayesian model” Find the full paper here: pubmed.ncbi.nlm.nih.gov/41478440/
pubmed.ncbi.nlm.nih.gov
Developmental differences in reward-learning and its connection to resting-state functional connectivity modeled using a hierarchical Bayesian model - PubMed
Adolescence is a period of heightened sensation-seeking, risk-taking, and reward sensitivity, characterized by structural and functional changes in the brain. Developmental changes in functional connectivity between cortical and subcortical regions may refine communication within reward-related circ …
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Tatjana Tchumatchenko @tatjanat.bsky.social · 10/01/2026
Please spread the word🔊My lab is looking to hire two international postdocs. If you want to do comp neuro, combine machine learning and awesome math to understand neural circuit activity, then come work with us! Bonn is such a cool place for neuroscience now, you don't want to miss out.
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Aleksandra Lazić, PhD @alelazic.bsky.social · 30/12/2025
Spent some time today playing around with the #Rstats package orchaRd 2.0 It offers a really nice way of visualizing #metaanalysis, especially moderator meta-regression models (with both categorical & continuous moderators!) #dataviz 🔗 daniel1noble.github.io/orchaRd/ 📄 doi.org/10.1111/2041...
Figure 4 from the linked paper.
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Quentin Huys @docqhuys.bsky.social · 21/12/2025
Postdoctoral research position in #ComputationalPsychiatry and #EEG as part of relmed.ac.uk trial testing reinforcement learning as biomarker for antidepressant treatment response. www.ucl.ac.uk/work-at-ucl/... @uclbrainscience.bsky.social @mikebrowning.bsky.social @relmed.bsky.social
relmed.ac.uk
Antidepressant treatment shouldn't be a guessing game. RELMED is working towards using advanced research to predict which medication is most likely to help each person along their individual path to recovery.
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Gordon Feld @gordonfeld.bsky.social · 19/12/2025
I have an early Christmas present for you! 🎅 Happy to announce that we have three excellent keynote speakers at Psychology and Brain 2026 in Heidleberg! Professors Shamay-Tsoory, Schönauer and Allen will cover topics from empathy over memory to interoception! pug2026.org
A picture of Shamay-TsooryA picture of Monika SchönauerA picture of Micah Allen
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Ole Jensen @olejensen.bsky.social · 11/10/2025
Ever wonder how you read so fast? Your brain gets a head start—processing the next word before your eyes move. Our MEG + eye tracking study out in Nature Communications study from @thechbh.bsky.social reveals orthographic & semantic previews predicting reading speed www.nature.com/articles/s41...
nature.com
Fast hierarchical processing of orthographic and semantic parafoveal information during natural reading - Nature Communications
Combining MEG, eye-tracking, and representational similarity analysis, this study shows that readers rapidly and sequentially extract orthographic and semantic information from upcoming words before fixation, supporting efficient reading.
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Valentin Riedl @vavatin.bsky.social · 16/12/2025
fMRI signals “up,” but neural metabolism might be going “down.” In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes. rdcu.be/eUPO8 funds @erc.europa.eu #neuroskyence 🧵:
BOLD signal changes can oppose oxygen metabolism across the human cortex, Nature Neuroscience
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Kristin Kaduk @kristinkaduk.bsky.social · 13/12/2025
Thrilled to share our paper is out now in @ebiomedicine.bsky.social 🥳 The interoception accuracy part is still my favorite 🤩 Have a look: www.thelancet.com/journals/ebi...
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Nils Kroemer @nbkroemer.bsky.social · 10/12/2025
What started as a spinoff project for Madeleine's PhD became one of the most striking indications that glucose levels play an important role in regulating everyday stress responses. This shows the potential of biosensors to evaluate whether metabolism alters stress reactivity #neuroskyence 🩺
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Madeleine Kördel @mkoerdel.bsky.social · 10/12/2025
📣I’m excited to share our new preprint on how our body’s energy supply shapes everyday stress experiences: 📄𝐇𝐢𝐠𝐡𝐞𝐫 𝐠𝐥𝐮𝐜𝐨𝐬𝐞 𝐥𝐞𝐯𝐞𝐥𝐬 𝐛𝐮𝐟𝐟𝐞𝐫 𝐚𝐠𝐚𝐢𝐧𝐬𝐭 𝐞𝐯𝐞𝐫𝐲𝐝𝐚𝐲 𝐬𝐭𝐫𝐞𝐬𝐬 𝐥𝐨𝐚𝐝 www.biorxiv.org/content/10.6...
biorxiv.org
Higher glucose levels buffer against everyday stress load
Adaptive stress responses are dependent on the availability of energy and the body's effectiveness in metabolizing glucose as fuel. However, it is not well understood if glucose levels contribute to t...
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Corinna Schulz @corcerebrum.bsky.social · 09/12/2025
Your stomach called – your striatum picked up! But does this actually happen in humans? Using simultaneous dopamine PET/fMRI, we show that the gut hormone ghrelin helps the brain adjust motivation to current metabolic need. Here’s what we found👇 Preprint: shorturl.at/pq4A3 #neuroskyence #🩺
Graphical visualization of the research question
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Nils Kroemer @nbkroemer.bsky.social · 08/12/2025
Out now in @ebiomedicine.bsky.social 🚨. Hunger often affects our mood, but is this a conscious or a subconscious process? Using continuous glucose monitoring, we show that differences in mood are driven by hunger ratings, not just glucose. #neuroskyence 🩺 www.thelancet.com/journals/EBI...
A graphical abstract showing the research question and the operationalization of the study.
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Maria Waltmann @mariawalt.bsky.social · 21/11/2025
Please share! - 🚨⚠️ PhD position alert ⚠️🚨 - Please share! Come work with @ldeserno.bsky.social and yours truly on an exciting DFG-funded project on the neurocognitive mechanisms of (noise in) learning and decision-making in development and ADHD!
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