iiinova — where your digital self keeps evolving

Reposted by Luisa Kaluza

Nils Kroemer @nbkroemer.bsky.social · 13/05/2026

This is us 🎈. The study was led by @corcerebrum.bsky.social and the @neuromadlab.bsky.social team.

Reposted by Luisa Kaluza

Nils Kroemer @nbkroemer.bsky.social · 28/03/2026

Can your brain's white matter proxies of inflammation re-identify you like a fingerprint? Turns out: yes, and we used this to psychometrically evaluate diffusion basis spectrum imaging and to detect depression-related changes in the cingulate bundle. #neuroskyence 🩺 www.medrxiv.org/content/10.6...

$Participants with major depressive disorder (MDD) show lower fiber fraction and higher hindered fraction in the cingulum bundle. We observed differences in the cingulum bundle with decreased fiber fraction (tmax=4.68, k=38, pFWE<.001), indicating reduced axonal integrity (left) and increased hindered fraction (tmax=4.74, k=32, pFWE<.001), suggesting edema (right) in participants with MDD vs. healthy control participants (HCP). These changes indicate increased white matter inflammation in participants with MDD. In voxels showing differences between HCP and MDD groups, the reliability of fiber fraction and hindered fraction was high (lower insets).$

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Reposted by Luisa Kaluza

Nils Kroemer @nbkroemer.bsky.social · 16/03/2026

A teaser for our upcoming preprint on the short-term test-retest reliability of diffusion basis spectrum imaging. Voxel-level reliability of hindered fraction (a proxy measure of edema) in white matter is good, particularly close to cortical gray matter. W/ @lhkal.bsky.social @akuehnel.bsky.social

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Reposted by Luisa Kaluza

Nils Kroemer @nbkroemer.bsky.social · 09/03/2026

I am enjoying a few uninterrupted hours of plotting today. Finally got my hands on our diffusion basis spectrum imaging data, and it looks good, particularly in white matter voxels. I hope we will have a preprint coming out in a few weeks, led by @lhkal.bsky.social & @akuehnel.bsky.social

Sneak peek of an inset of the results figures from our diffusion basis spectrum imaging data.

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Reposted by Luisa Kaluza

Nils Kroemer @nbkroemer.bsky.social · 17/12/2025

Last preprint 🎶(of the year). If vagus nerve stimulation alters motivation by amplifying internal signals, then bodily states should matter. Using milkshake vs. water loads, we show that tVNS-induced changes in Pavlovian bias are dependent on hunger. #neuroskyence 🩺 www.biorxiv.org/content/10.6...

A figure showing that non-invasive transcutaneous vagus nerve stimulation (tVNS) modulates Pavlovian bias in a state-dependent manner. A milkshake vs. water load reduces hunger and these changes are associated with the effects of tVNS on Pavlovian bias.

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