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Ildem Akerman Lab

@akermanlab.bsky.social
166 followers 154 following 13 posts

All things pancreatic beta cell. Transcriptional regulation, functional genomics and more recently stem cell generated beta cells. Academic lead for BetaCell Birmingham @University of Birmingham UK

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Reposted by Ildem Akerman Lab
Daniel Drucker @danieljdrucker.bsky.social · 10/11/2025
Deadlines are approaching (some next week!) for @keystoneSymposia.bsky.social #IsletBiology & #Diabetes : #BetaCell Compensation, Failure & Recovery, this March in Breckenridge! See scholarship, abstract and discount reg dates: keysym.us/KSDiabetes26 #KSDiabetes26
keysym.us
Islet Biology and Diabetes: Beta Cell Compensation, Failure and Recovery | Keystone Symposia
Join us at the Keystone Symposia on Islet Biology and Diabetes: Beta Cell Compensation, Failure and Recovery, March 2026, in Breckenridge, with field leaders!
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Reposted by Ildem Akerman Lab
Jorge Ferrer @jorge-ferrer.bsky.social · 23/10/2025
Many exciting opportunities for a PhD in Life Sciences in CRG, Barcelona. If you are interested in Genomics of Diabetes check out the offer for a fully funded fellowship in our lab - we will consider candidates with experimental or computational backgrounds. Please spread the word!
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Reposted by Ildem Akerman Lab
Vancouver Coastal Health Research Institute @vchresearch.bsky.social · 14/11/2025
This #WorldDiabetesDay, discover the effects of low & high blood sugar, as well as science-backed management strategies & emerging treatments for type 1 diabetes from VCHRI expert Dr. Breay Paty:
vchri.ca
Ask an expert: How can I manage my type 1 diabetes?
Approximately 300,000 Canadians live with type 1 diabetes, an autoimmune disorder with no known cure. Type 1 diabetes can pose serious challenges, but ongoing research is improving the quality of life for those with this chronic condition. Endocrinologist Dr. Breay Paty discusses the effects of low and high blood sugar, as well as science-backed management strategies and emerging biological treatments for type 1 diabetes.
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Reposted by Ildem Akerman Lab
Daniel Drucker @danieljdrucker.bsky.social · 12/11/2025
Extraislet β cells are virtually absent in the human #T1D pancreas www.science.org/doi/10.1126/...
science.org
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Ildem Akerman Lab @akermanlab.bsky.social · 11/11/2025
University of Birmingham is recruiting!! Fellows, chairs! Please do get in touch with me if you are a beta cell or diabetes researcher interested in applying! www.birmingham.ac.uk/jobs/125th-a...
birmingham.ac.uk
125th Anniversary Fellows and Chairs - University of Birmingham
125th Anniversary Fellows and Chairs
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 10/03/2025
We're looking for postdoctoral scholars to join our team in Vancouver 🇨🇦. We work on cell-based approaches aimed at curing type 1 diabetes. Bring your own ideas for projects or work on one that's already funded! More details here: www.nature.com/naturecareer...
nature.com
Postdoctoral Research Fellow - Vancouver, British Columbia (CA) job with University of British Columbia Department of Surgery | 12837375
The successful candidate will work on a project developing cell-based therapies for those living with type 1 diabetes (T1D).
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Reposted by Ildem Akerman Lab
Daniel Drucker @danieljdrucker.bsky.social · 15/07/2025
A regulated pathway through which glucagon modulates insulin release via alpha to beta cell communication and control of GLP-1R internalization and beta cell Ca2+ responses to high glucose @cp-cellmetabolism.bsky.social @daveyboyhod.bsky.social #islets www.cell.com/cell-metabol...
cell.com
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication
Tong et al. utilize advanced imaging approaches to reveal that beta cells located next to alpha cells are specially adapted as glucagon sensors by virtue of their high expression levels of GLP1R. Thes...
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Reposted by Ildem Akerman Lab
Patrick MacDonald🇨🇦 @bcellorg.bsky.social · 08/07/2025
We are launching a new initiative to support experimental design, data management/analysis and bioinformatics. Early days yet, but check it out here. www.bcell.org/adi-datasci....
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 21/06/2025
Stem cell islets for those living with T1D! www.nejm.org/doi/full/10....
nejm.org
Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM
Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...
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Ildem Akerman Lab @akermanlab.bsky.social · 21/06/2025
A huge step forward for cell replacement therapy for #T1D @NEJM Vertex clinical trials for zimislecel www.nejm.org/doi/full/10....
nejm.org
Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM
Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...
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Reposted by Ildem Akerman Lab
EISG 2025 @eisg2025.bsky.social · 12/06/2025
🧫 We have a packed programme for the second day of the European Islet Study Group conference in Malmö. One of the highlights of today is the keynote lecture by Lori Sussel from University of Colorado. She presents research about the regulation of islet cell fates. #eisg2025 #diabetes
Photograph of Lori Sussel.
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Spagnoli_Lab. @labspagnoli.bsky.social · 23/04/2025
www.nature.com/articles/s41...
nature.com
Spatial mapping of transcriptomic plasticity in metastatic pancreatic cancer - Nature
Spatially resolved transcriptomic profiling of primary tumours and metastases from patients with pancreatic cancer provides insight into the evolutionary progression to metastasis, and the variation in clonal architecture within and between individuals.
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Wiebke Arlt @wiebkearlt.bsky.social · 19/02/2025
Calling clinician scientists with focus on mechanistic discovery science and experimental medicine who recently have completed or are about to complete their clinical training - great opportunity! Please re-skeet and apply to @mrc-lms.bsky.social by 4th March 2025 lms.mrc.ac.uk/work/vacanci...
lms.mrc.ac.uk
Chain Florey Post CCT Transition to Independence Fellowship - MRC Laboratory of Medical Sciences
The Chain Florey Transition-to-Independence (TTI) Fellowship scheme provides a unique opportunity to clinician scientists who have recently completed their clinical training (or will do so in the next...
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Wiebke Arlt @wiebkearlt.bsky.social · 11/04/2025
EUWIN - European Women in Endocrinology - join us in Copenhagen this May!
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Spagnoli_Lab. @labspagnoli.bsky.social · 17/04/2025
🚨🚨 New pre-print from the lab. led by the amazing @alejotorrescano.bsky.social ! Alejo & Co. elegantly decode the spatial logic of progenitor cell organization in the developing pancreas — from individual cells to structured cellular communities 🔬🔬🧫🧪 Check-it out ⤵️
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 04/04/2025
1 day left to apply!
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Jim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · 04/04/2025
Canadian Diabetes Job! www.nature.com/naturecareer...
nature.com
Professors (2 positions) - Canada Excellence Research Chairs - Health - Sherbrooke (City), Quebec (CA) job with Universite de Sherbrooke | 12837575
Université de Sherbrooke is inviting applications for two professor positions, with the selected candidates expected to hold a prestigious chair
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Ildem Akerman Lab @akermanlab.bsky.social · 31/03/2025
This issue of The Endocrinologist is dedicated to diabetes research (our SC-islets on the cover!) www.endocrinology.org/endocrinolog...
endocrinology.org
155 Spring 25 | Society for Endocrinology
The Society for Endocrinology aims to promote the advancement of public education in endocrinology
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EISG 2025 @eisg2025.bsky.social · 26/03/2025
📢 Remember that the Abstract Submission Deadline for #EISG2025 is on April 1st! 📢 Don't miss your chance to share your research at the European Islet Study Group 2025 in Malmö, June 11-13! 🏙️🇸🇪 🔗 Submit your abstract by April 1st: eisg2025.se #DiabetesResearch #CallForAbstracts
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Ildem Akerman Lab @akermanlab.bsky.social · 11/03/2025
We are looking for a keen bioinformatician for a fully funded PhD position! Drop me an email with your CV! www.findaphd.com/phds/project...
findaphd.com
PhD Opportunity in Bioinformatics – Fully Funded for UK Home Fee Students at University of Birmingham on FindAPhD.com
PhD Project - PhD Opportunity in Bioinformatics – Fully Funded for UK Home Fee Students at University of Birmingham, listed on FindAPhD.com
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EISG 2025 @eisg2025.bsky.social · 10/03/2025
🚨 3 DAYS LEFT! 🚨 The countdown is on — early bird registration for #EISG2025 closes March 13! ⏳🏃‍♂️ Secure your spot and submit your abstract to join the European Islet Study Group 2025 in Malmö, June 11-13. 🏙️✨ 🔗 Register now: eisg2025.se #DiabetesResearch
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 25/02/2025
Our job posting for 1 or more PDF positions in Vancouver Canada is now live here: tinyurl.com/4mrjw3m2 Please share/repost and apply soon!
tinyurl.com
Postdoctoral fellow
Academic Job Category Faculty Non Bargaining Job Title Postdoctoral fellow Department Lynn Research Lab General Surgery | Department of Surgery | Faculty of Medicine (Francis Lynn) Posting End Date Ap...
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Patrick MacDonald🇨🇦 @bcellorg.bsky.social · 21/02/2025
We link molecular and functional phenotypes of islet cells from donors with type 1 diabetes to understand impaired insulin and glucagon secretion. Immune signalling, nuclear exclusion, mTOR and lysosomes in alpha cell dysfunction. www.biorxiv.org/content/10.1101/202…
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 15/02/2025
I have funding through at least 2031 for postdoctoral researchers with expertise in islet biology or cell-based therapies for, or modelling of, diabetes. Bring your expertise to a country that values it. 🇨🇦 Contact info on my website.
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 08/02/2025
We are recruiting for the Head of the Division of Endocrinology at BC Children’s Hospital, @bcchresearch.bsky.social and @ubcmedicine.bsky.social. Please apply! jobs.phsa.ca/job/vancouver/head-div…
jobs.phsa.ca
Head, Division of Endocrinology - BC Children’s Hospital & University of British Columbia at PHSA
Learn more about applying for Head, Division of Endocrinology - BC Children’s Hospital & University of British Columbia at PHSA
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NC3Rs @nc3rs.bsky.social · 03/02/2025
⏳ There is one week left to submit your 3Rs Challenge idea for the 2025 CRACK IT open call. Download the form today and submit to crackitenquiries@nc3rs.org.uk by Monday 10 February: nc3rs.org.uk/crackit/spon...
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Jorge Ferrer @jorge-ferrer.bsky.social · 02/02/2025
Still time to apply! Applications from US welcome – four years can feel longer or shorter depending on where you are 😉
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Kara McKinley @karalmckinley.bsky.social · 29/01/2025
I have a wonderful scientist in my lab who is looking to move to Europe. Is anyone looking for a staff scientist? She has a PhD. She is particularly in her element doing field work. Great skills with rodents and very open to non-rodent positions as well. Please send leads, please amplify!
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Nature @nature.com · 25/01/2025
A rapid and efficient method developed to create stem-cell-based 3D mini-organs derived from the cells of patients offers a way to evaluate personalized treatments using RNA therapies for rare genetic diseases go.nature.com/3POiHpJ
go.nature.com
A scalable system using mini-organs to test personalized RNA therapy
Platform to accelerate the testing of antisense oligonucleotides.
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 22/01/2025
We have room and $ for postdoctoral fellows to join our team in beautiful Vancouver 🇨🇦. Get in touch if interested.
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 08/01/2025
If you’re interested in doing Postdoc work in Vancouver this is a great opportunity, check out our website and get in touch soon (www.betacell.ca)!
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Jorge Ferrer @jorge-ferrer.bsky.social · 31/12/2024
📣 Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. Computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested @crg.eu shorturl.at/O3wMi shorturl.at/ieyZy
shorturl.at
Postdoctoral scientist, gene regulatory mechanisms and diabetes | CRG Online Recruitment Portal
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
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Ildem Akerman Lab @akermanlab.bsky.social · 30/12/2024
Last day to apply!!
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Anna Gloyn @annagloyn.bsky.social · 24/12/2024
Excited to have been involved in this: The utility of at home continuous glucose monitoring coupled with machine learning to predict metabolic subtypes. Study was led by Mike Synder & Tracey McLaughlin & championed by Ahmed Metwally. @natureportfolio.bsky.social www.nature.com/articles/s41...
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Jorge Ferrer @jorge-ferrer.bsky.social · 21/12/2024
Join us in a beautiful location for this multidisciplinary experience. Top speakers linking topics such as organoid modeling, synthetic biology, gene regulation or genetics with disease mechanisms & new therapies for T1D, T2D, and MASLD meetings.embo.org/event/25-liver-pancreas
meetings.embo.org
Liver and pancreas in metabolic disease: from pathways to therapies
The liver and pancreas arise from a common developmental origin and are controlled by shared gene regulatory programs.These organs are central to two of the most common and devastating metabolic dise…
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Heiko Lickert @heikolickert.bsky.social · 19/12/2024
My top highlight for 2025 - EMBO workshop in Saint Feliu - three exciting days of science crossing boundaries of liver & pancreas research! Co-organised by @CebolaLab @1jorgeferrer @VallierLab @LickertHeiko & Emma Anderson #livertwitter #islets #masld #diabetes meetings.embo.org/event/25-liv...
meetings.embo.org
Liver and pancreas in metabolic disease: from pathways to therapies
The liver and pancreas arise from a common developmental origin and are controlled by shared gene regulatory programs.These organs are central to two of the most common and devastating metabolic dise…
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Nature @nature.com · 19/12/2024
We've just joined Bluesky 🎉 Follow us for research, news, comment and opinion from Nature journal 🧪
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Ildem Akerman Lab @akermanlab.bsky.social · 19/12/2024
Fancy 4 more years of beta cells? We are hiring a genomics post-doctoral researcher to join our team! Closing: 1st Jan, interviews: 13 Jan.. More info & application: www.birmingham.ac.uk/jobs Search JOB ID: 104642
birmingham.ac.uk
Jobs at the University of Birmingham - University of Birmingham
Search our latest jobs and find out what benefits are offered to our staff at the University of Birmingham.
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Wiebke Arlt @wiebkearlt.bsky.social · 17/12/2024
We are hiring! Programme Leader Track positions @mrc-lms.bsky.social up for grabs by up-and-coming researchers with a great start to their career who now aim to establish their own group in a translational discovery science institute of world leading excellence. lms.mrc.ac.uk/work/vacanci...
lms.mrc.ac.uk
Programme Leader Track - MRC Laboratory of Medical Sciences
Programme Leader Track appointments are an open-ended contract, which comprises a six-year advanced career development scheme after which you will be considered for promotion to Programme Leader.
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 20/11/2024
Great to have this paper out in diabetesjournals.org/diabetes! Appreciate the feedback from reviewers and funding from BreakthroughT1D that made this work possible. pubmed.ncbi.nlm.nih.gov/39561351/
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Fabian Theis @fabiantheis.bsky.social · 12/12/2024
1/🚀 Excited to share RegVelo, our new cell model combining RNA velocity with gene regulatory network (GRN) dynamics to model cellular changes and predict in silico perturbations. Here's how it works and why it matters! 🧵👇 biorxiv.org/content/10.1101/2024.12.11.627935v1
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NC3Rs @nc3rs.bsky.social · 10/12/2024
We have committed £4.85M to accelerate the uptake of non-animal approaches, supported by the Department for Science, Innovation and Technology. The 21 funded projects include collaborations across disciplines, sectors and institutes nationwide: nc3rs.org.uk/news/ps485m-...
Composite image showing examples of non-animal methods and products that can be non-animal derived, clockwise from top left antibodies, cell culture flask, scaffold for 3D cell culture and computer screen.
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Ildem Akerman Lab @akermanlab.bsky.social · 10/12/2024
We are delighted to recieve a perfusion based bioreactor to upscale our production at BetaCell Birmingham! We believe availability of Stem-cell derived beta cells can help relace mouse derived islet use in diabetes research...
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Ildem Akerman Lab @akermanlab.bsky.social · 09/12/2024
Interesting read!
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Alejo Torres @alejotorrescano.bsky.social · 06/12/2024
Excited to hear about Dr. Aida Martinez research (@aidamartinezs.bsky.social) next CGTRM Stem cells @ Lunch seminar on Tuesday 10th Dec 2PM BST!
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Heiko Lickert @heikolickert.bsky.social · 25/11/2024
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
doi.org
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
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