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Adrian Ranga

@adrianranga.bsky.social
162 followers 365 following 0 posts

Bioengineer using organoids to understand patterning and morphogenesis. Associate Professor @kuleuvenuniversity.bsky.social

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Reposted by Adrian Ranga
Claire Dessalles @clairedessalles.bsky.social · 22/04/2026
All you ever wanted to know about how to analyse the nematic nature of cellular tissues is right here 👀👇🏼! Bonus #1: we did it for many cell types and uncovered unexpected defect behavior 🐌 Bonus #2: for theoreticians looking for parameter values for your simulation🧑🏼‍💻 tinyurl.com/2s399yen
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Reposted by Adrian Ranga
Xavier Trepat @xaviertrepat.bsky.social · 17/04/2026
Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.
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Reposted by Adrian Ranga
Alfonso Martinez Arias @amartinezarias.bsky.social · 04/04/2026
Because #gastruloids allow measurements, they can teach us about quantitative traits. Exploring #CellCompetiion @joshifrenster.bsky.social et al www.nature.com/articles/s41... Biology as a matter of #Genes #Cells and #Numbers but of much that is #NotInTheGenes
nature.com
Mosaic gastruloids reveal a temporal restriction for developmental cell competition - Nature Cell Biology
Frenster et al. utilize mosaic mouse gastruloids as a model of cell fitness and competition, identifying a temporal window between primed pluripotency and early gastrulation during which cell competit...
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Reposted by Adrian Ranga
Ricard Solé @ricardsole.bsky.social · 04/04/2026
Why does cancer arise across such diverse life forms? The answer lies in evolution. This @royalsocietypublishing.org issue shows how cancer emerges as a breakdown of cooperation in multicellular organisms. @multicellgenome.bsky.social @mkhochb.bsky.social royalsocietypublishing.org/doi/abs/10.1...
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Reposted by Adrian Ranga
BaCell3D @bacell3d.bsky.social · 24/06/2025
A great talk by @adrianranga.bsky.social on in vitro neural tube morphogenesis! Interesting findings on the role of calcium waves preceding tissue movements!
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Reposted by Adrian Ranga
Alfonso Martinez Arias @amartinezarias.bsky.social · 08/06/2025
Very important @nicolettapetridou.bsky.social‬ report #mechanochemical signalling control fate transitions www.biorxiv.org/content/10.1... w/ wide/significant implications. Perhaps the clearest indication so far of HOW #NotInTheGenes cell interactions mechanical pattern gene expression #MustRead
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Reposted by Adrian Ranga
bedzhov lab @bedzhovlab.bsky.social · 28/05/2025
Protocol for 3D In Vitro Culture of Early Mouse Embryos and Trophoblast Tissue Explants link.springer.com/protocol/10.... Congratulations to Devila, Shashank and Nirai, and thanks to Adrian for his instrumental support @adrianranga.bsky.social @mpi-muenster.bsky.social @sfb1348.bsky.social
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Reposted by Adrian Ranga
hpscenthusiast.bsky.social @hpscenthusiast.bsky.social · 23/05/2025
Hello Bluesky world! 🚨New Preprint 🚨 Thrilled to share my second paper from my PhD in the @glgalea.bsky.social lab. @ucl.ac.uk doi.org/10.1101/2025...
doi.org
Patient-specific iPSC models of neural tube defects identify underlying deficiencies in neuroepithelial cell shape regulation and differentiation
Spina bifida and anencephaly are neural tube defects caused by failure of embryonic neural tube closure. Successful closure requires elongation and apical constriction of neuroepithelial cells. These ...
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Reposted by Adrian Ranga
Arthur Michaut 🔬🐣 @amichaut.bsky.social · 12/05/2025
🚨📣 New preprint alert! Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos! A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social 📄 www.biorxiv.org/content/10.1... #devbio #mechanics
biorxiv.org
Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis
Despite progress in probing tissue mechanics, direct long-term measurements in live embryonic epithelia are lacking. This limits our understanding of amniote embryonic morphogenesis, which takes place...
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Reposted by Adrian Ranga
Christie Wilcox @nerdychristie.bsky.social · 08/04/2025
How did life go from solo cells to many coordinating ones? Perhaps a bit of pressure. That story and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪
When subjected to mechanical pressure, the salt-loving archaeon Haloferax volcanii grows bigger and bigger before fragmenting into a tissue-like, multicellular network.  Rados et al./Science (2025)
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Reposted by Adrian Ranga
Shashank Shekhar lab @sshekhr.bsky.social · 17/04/2025
Actin ❤️
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