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hpscenthusiast.bsky.social

@hpscenthusiast.bsky.social
36 followers 36 following 4 posts
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Afnan Azizi @stochastalive.bsky.social · 01/04/2026
Excited to share our new #preprint uncovering how early human forebrain is patterned. Compared to mouse, human dorsoventral and anteroposterior telencephalon patterning is strikingly delayed, which is correlated with SHH and FGF signalling differences. Read it here: www.biorxiv.org/content/10.6...
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Reposted by @hpscenthusiast.bsky.social
Eirini Maniou @emaniou.bsky.social · 26/03/2026
Excited to share our new publication on the mechanics of cranial neural tube closure. A really enjoyable and fruitful collaboration bridging Developmental Biology and biophysical modelling. Take a look here! www.cell.com/current-biol...
cell.com
Mechanosensitive feedback organizes cell shape and motion during hindbrain neuropore morphogenesis
Pérez-Verdugo et al. show that hindbrain neuropore closure is driven by surface ectoderm actomyosin purse-string tension and active migration. These forces create reproducible patterns of cell elongat...
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Reposted by @hpscenthusiast.bsky.social
Ina @inaharasimov.bsky.social · 24/03/2026
Cytoplasmic lattices are a highly abundant and essential structure in mouse oocytes and embryos. Our in situ structure from early mouse embryos provides a new insight into their molecular achitecture and function. Check it out: www.biorxiv.org/content/10.6...
biorxiv.org
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hpscenthusiast.bsky.social @hpscenthusiast.bsky.social · 22/01/2026
It was our pleasure to have @emaniou.bsky.social at @universitypress.cambridge.org talking about her recent ongoing work as a group leader in @dublincityuni.bsky.social.
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Reposted by @hpscenthusiast.bsky.social
Joaquina Delas @joadelas.bsky.social · 12/11/2025
We have a new lab photo. Busy times in the Delas Lab! Last month Maria and Shaun joined us to start their PhDs. Learn more about our research and our team: delaslab.com We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.
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epithelial mechanics fan club @epimechfc.bsky.social · 02/11/2025
Which features of tissue flows are most robust and how do they emerge from #EpithelialMechanics? I’m @alex-plum.bsky.social (@mattiaserra.bsky.social group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
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Reposted by @hpscenthusiast.bsky.social
Eirini Maniou @emaniou.bsky.social · 07/07/2025
PhD position available in our team @dublincityuni.bsky.social from September. Please share/ contact me for informal enquiries.
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FocalPlane @focalplane.bsky.social · 27/06/2025
📢Our latest preprint list is now up on FocalPlane. This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included. focalplane.biologists.com/2025/06/27/m...
focalplane.biologists.com
Microscopy preprints - applications in biology - FocalPlane
Microscopy preprints - applications in biology - News
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Reposted by @hpscenthusiast.bsky.social
Eirini Maniou @emaniou.bsky.social · 26/06/2025
Excited to share I’m starting my group in Dublin this September, supported by a Research Ireland Pathway award. We will work on neurulation mechanics using chicken embryos and human iPSCs. Looking forward to this new adventure! #newPI #womeninSTEM
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Gabriel Galea @glgalea.bsky.social · 20/05/2025
2. iPSC neuroepithelial models by @hpscenthusiast.bsky.social identifying a patient mutation in VANGL2 which diminishes apical constriction in this human model www.biorxiv.org/content/10.1...
Figure excerpt showing recoil following annual laser ablation of WT and VANGL2-knock in neuroepithelial cultures
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hpscenthusiast.bsky.social @hpscenthusiast.bsky.social · 23/05/2025
Hello Bluesky world! 🚨New Preprint 🚨 Thrilled to share my second paper from my PhD in the @glgalea.bsky.social lab. @ucl.ac.uk doi.org/10.1101/2025...
doi.org
Patient-specific iPSC models of neural tube defects identify underlying deficiencies in neuroepithelial cell shape regulation and differentiation
Spina bifida and anencephaly are neural tube defects caused by failure of embryonic neural tube closure. Successful closure requires elongation and apical constriction of neuroepithelial cells. These ...
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