iiinova — where your digital self keeps evolving

Adam MacLean @adamlmaclean.bsky.social · 05/10/2026

Please share! Applications open now to our comp bio PhD program at USC ⭐️ 40+ years of computational biology ⭐️ Yet we do not stand still! ⭐️ Join 12+ core and 30+ joint faculty at the cutting edge of biology ⭐️ Genomics, epigenetics, ML + AI, systems biology, population genetics, +++ Come join us 🚀

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Adam MacLean @adamlmaclean.bsky.social · 20/09/2026

We are hiring! Come join us in the Quantitative and Computational Biology department at USC as a teaching-track faculty member. 👉 Apply by Dec 1st. usccareers.usc.edu/job/los-ange...

usccareers.usc.edu

Full-Time, Teaching-Track Faculty Position in Quantitative and Computational Biology at USC

Learn more about applying for Full-Time, Teaching-Track Faculty Position in Quantitative and Computational Biology at USC

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Joseph Fasano @josephfasano.bsky.social · 24/08/2026

Back to school. ❤️

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i am 40 fish all hungry for meat @carbidecarbon.bsky.social · 07/04/2026

they really said "they should have sent a poet"

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Adam MacLean @adamlmaclean.bsky.social · 27/02/2026

Post a pic, no context, to bring some zen to the feed.

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Adam MacLean @adamlmaclean.bsky.social · 20/01/2026

Shout this from the rooftops! ALSO: PIs who must decline reviews, please nominate the qualified students and postdocs from your lab!

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Adam MacLean @adamlmaclean.bsky.social · 08/01/2026

As I hurtle headlong towards the coming semester, I am really feeling these epic closing words of advice from Gian-Carlo Rota. [very grateful to the transcription from Leo Goldmakher, h/t @lianafaye.bsky.social] web.williams.edu/Mathematics/...

A screenshot of the following text:
"A teacher of undergraduate courses belongs in a class with P.R. men, with entertainers, with propagandists, with preachers, with magicians, with gurus. Such a teacher will be successful if at the end of the course every one of his or her students feels they have taken “a good course,” even though they may not quite be able to pin down anything specific they have learned in the course."

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Adam MacLean @adamlmaclean.bsky.social · 10/12/2025

This is fascinating! I thought I saw some flowering driving down the 395 over the weekend (near the 14 junction) but I did not take any pictures.

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Adam MacLean @adamlmaclean.bsky.social · 10/12/2025

Yes except in my head it has to be Ofc. ofc just looks odd 🤷‍♂️

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Michael Baym @baym.lol · 20/11/2025

Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/ www.science.org/doi/10.1126/...

science.org

Intracellular competition shapes plasmid population dynamics

From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...

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The Company of Biologists @biologists.bsky.social · 29/10/2025

Thank you Adam Maclean @adamlmaclean.bsky.social for sharing your experience of fee-free Open Access publishing in @dev-journal.bsky.social via our Read & Publish agreement with The University of Queensland. See all institutions: www.biologists.com/library-hub/... #OA #OpenAccess #ReadAndPublish

"I was delighted to publish an article in Development fee-free thanks to the Read & Publish agreement between the University of Southern California and The Company of Biologists. Not only is it a huge benefit for researchers to be able to publish Open Access while navigating uncertain funding environments, but I am thrilled that my institution and others through such agreements support The Company of Biologists: a not-for-profit publisher with a track record of supporting scientists and the work they do." Adam L. MacLean, University of Southern California, USA

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Adam MacLean @adamlmaclean.bsky.social · 21/10/2025

The ability of kids to convince me they know more than they know is truly amazing. Exhibit: family charades. I am acting, 7yo is guessing. One word; two syllables. Meaning: something you eat with that is not a spoon. First syllable: chop. Second syllable: rhymes with lick. 7yo: Knife!

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Adam MacLean @adamlmaclean.bsky.social · 14/10/2025

we aren't allowed to write cocaine?

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Adam MacLean @adamlmaclean.bsky.social · 13/10/2025

Cool paper. Was the ad hominem really necessary though? www.science.org/doi/10.1126/...

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Paul Macklin @mathcancer.bsky.social · 01/10/2025

Really enjoyed talking about mathematical biology (and a little about being an associate dean) in @parmvir.com's Biology in Numbers podcast on the 2025 @smbmathbiology.bsky.social annual meeting! Bolero superfans, don't @ me! 🧪 (I'm at 33:43) podcasts.apple.com/us/podcast/b...

podcasts.apple.com

S3 Ep1: SMB 2025

Podcast Episode · Biology in Numbers · 09/29/2025 · 53m

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Rita Strack @ritastrack.bsky.social · 30/09/2025

Please start following @natbiomedeng.nature.com! It's an alive account now and we will start posting good content!

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Adam MacLean @adamlmaclean.bsky.social · 01/10/2025

Who knows if the cows were more or less interested in my poster than the poster session attendees would have been. Also good idea @mathcancer.bsky.social to flip the script, it was great to hear from our host Parmvir too!

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Adam MacLean @adamlmaclean.bsky.social · 01/10/2025

This was fun and great to learn about the research (and trivia) of colleagues from #SMB2025 this summer in Edmonton. Thanks to @parmvir.com for hosting a great podcast 🙌 🧬 🔢 podcasts.apple.com/us/podcast/s...

podcasts.apple.com

S3 Ep1: SMB 2025

Podcast Episode · Biology in Numbers · 09/29/2025 · 53m

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Javier del Campo @fonamental.bsky.social · 22/09/2025

Phylogenetic tree inference from single-cell RNA sequencing data www.biorxiv.org/content/10.1... #singlecell

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Jazlyn Mooney @jazlynmooney.bsky.social · 22/09/2025

Super excited to see our reference bias work out in Cell! Reviewers gave us some excellent ideas, and Maria added on some new analyses that broke down how SNPs from heterospecific references mapped or did not map in a conspecific reference.

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Adam MacLean @adamlmaclean.bsky.social · 13/08/2025

Online now! Tumor dynamics & spatial proteomics-informed personalized predictions of growth & response Beyond RECIST: mathematical modeling and Bayesian inference reveal the importance of immune parameters in metastatic breast cancer www.biorxiv.org/content/10.1...

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Adam MacLean @adamlmaclean.bsky.social · 28/07/2025

"When they see us coming The birdies all try an' hide But they still go for peanuts When coated with cyanide."

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MathOnco @mathonco.bsky.social · 25/07/2025

In this week's post Jesse Kreger (@adamlmaclean.bsky.social‬) discusses his latest work in #cancer #systems #immunology together with Edgar Gonzalez to study the mechanisms of response of breast cancer to #checkPointInhibitors

mathematical-oncology.org

Discovering mechanisms of response via CSI (Cancer Systems Immunology)

mathematical-oncology.org

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Adam MacLean @adamlmaclean.bsky.social · 19/07/2025

Thanks for the great science and great company. Next year will be time to swap the poutine for pilsner and I'll hope to see you in Graz! #SMB2025

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Adam MacLean @adamlmaclean.bsky.social · 19/07/2025

For the most part everything ran on time! Also crucial to success of course, as well as being just good manners. I wholeheartedly endorse the session chair energy of Kelsey Gasior: "If you run over time, I will body slam you off stage."

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Adam MacLean @adamlmaclean.bsky.social · 19/07/2025

I was overall really impressed with the organization, bravo to the team. The venue worked well; this is IMO crucial to a great conference experience in that it permits ease of hopping between parallel sessions (bar a few squeaky doors) to cram in as many minisymposia talks as is humanly possible.

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Adam MacLean @adamlmaclean.bsky.social · 19/07/2025

In terms of themes, I feel like more than even I saw an emphasis on rigorous inference of one's models to data, not just in methods talks but in applications; big fan of that! I also appreciated great talks that dug deep into complex tumor microenvironments and cell state transitions within them.

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Adam MacLean @adamlmaclean.bsky.social · 19/07/2025

Couldn't leave Canada without breakfast poutine. Some scattered thoughts and Takeaways from #SMB2025... I had a super fun week, so many conversations, short and long, with science friends old and new.

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Adam MacLean @adamlmaclean.bsky.social · 18/07/2025

Yep. There are a lot that don't say a lot.

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Adam MacLean @adamlmaclean.bsky.social · 18/07/2025

Mohit Jolly kicking off the last day of #SMB2025 presenting a compelling case for understanding EMT via gene exp "teams" Ending with a heartfelt shoutout to the 'SMB team' Q: Which is more important: the journey or the destination? A: the company.

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Adam MacLean @adamlmaclean.bsky.social · 16/07/2025

Fantastic plenary this morning from @yosoykit.bsky.social highlighting the power of stochastic processes to inform clinical decision-making in gastrointestinal cancers. #SMB2025

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Adam MacLean @adamlmaclean.bsky.social · 15/07/2025

Followed by a compelling description of the genome as a bureaucracy... even if we argue over the relative utility of the information processing capabilities of the cell, it's redundancies (compared to human-made systems) are impressively expansive. #SMB2025

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Adam MacLean @adamlmaclean.bsky.social · 15/07/2025

Kicking off day 2 is plenary from Fred Adler with some lovely badly-drawn diagrams, always great to see alternatives to the hegemony of the diagrammatically bland biorender et al. #SMB2025

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Jason Moore @moorejh.bsky.social · 15/07/2025

#medicaid HT The New Yorker

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Adam MacLean @adamlmaclean.bsky.social · 15/07/2025

"Patients should be their own control" - great & pithy takeaway from @sandyanderson.bsky.social in his talk on the adoption of adaptive therapies in the clinic #SMB2025 #MathOnco

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Sandy Anderson @sandyanderson.bsky.social · 14/07/2025

Next up is former student & friend @stroblmar.bsky.social presenting new work with @cancerconnector.bsky.social on “Bridging the gap: What preclinical experiments can teach us about cancer drug scheduling” #MathOnco #SMB2025

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Adam MacLean @adamlmaclean.bsky.social · 14/07/2025

#SMB2025 check out this app to manage your minisymposia scheduling (always an intricate dance to get to all the interesting talks) ...also offers talk recommendations and "poster buddies"

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Adam MacLean @adamlmaclean.bsky.social · 14/07/2025

Nice, this looks great for schedule planning!

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Adam MacLean @adamlmaclean.bsky.social · 12/07/2025

... 🎤 👈 hello? Is #SMB2025 a thing? Are people* here? *society for mathematical biologists that is; nothing against single-molecule biophysicists per se.

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Adam MacLean @adamlmaclean.bsky.social · 12/07/2025

YES and I will trade you a math joke.

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Adam MacLean @adamlmaclean.bsky.social · 24/06/2025

I am also enamored with our new tree… #12512 in the forest: a pedunculate oak of the most elegant sorts, the company of which one delights in, especially compared to those inelegant stalks of the sessiles. 😉 forest.biologists.com/landscape/?i...

forest.biologists.com

Landscape - The Forest of Biologists

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Adam MacLean @adamlmaclean.bsky.social · 24/06/2025

I also want to thank the editors and staff at @dev-journal.bsky.social …great peer review experience from start to finish. Shout out to copy editors who still actually copy edit! Next time you get mad/sad at Big Publish, support @biologists.bsky.social!

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