Abstract. Building complex RNA nanostructures requires precise molecular connectors for controlled self-assembly. Existing connectors, such as kissing loop

DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are upt...

Ribozymes enable sequence-encoded turnover of RNA droplet material, resulting in transiently active droplets that selectively segregate based on their genotype. This establishes a direct link between...

The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a   Tenure Track Professors...

The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organisation, and one of the world’s leading research institutions. An intergovernmental organisation of 29 Member S...

Engineering Life 2025, biological forces, force spectroscopy, measuring forces, developmental forces, molecular motors, forces in morphogenesis, cytoskeleton, DNA mechanics, bionanotechnology

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YouTube video by UniHeidelberg

This Perspective highlights bottom-up molecular engineering and modular nanobiotechnological approaches for developing effective immunotherapeutics and their potential in personalized medicine.

The PRISM-MS workflow transforms single-cell mass spectrometry imaging by allowing detailed analysis of low-mass metabolites in large cell populations without metabolite degradation. By introducing n...

Ingenieure, Informatiker, Chemiker und Biologen kreieren künstliche biologische Systeme. Die synthetische Biologie verändert die Zukunft und definiert die Grenzen der Wissenschaft neu.

To realize the full potential of RNA nanotechnology and RNA origami, user-friendly design tools are needed. Here, we present pyFuRNAce, an open-source, Python-based software package with a graphical u...

🧬Great opportunity for exchange between representatives of biotech companies, researchers, and transfer technology experts happened during Germany's largest biotech event, the #GermanBiotechDays20...

This study introduces RNA origami nanotubes as self-assembling cytoskeleton mimics for synthetic cells. Expressed in vesicles from DNA templates, these RNA structures reach micrometre lengths, deform ...

This study introduces RNA origami nanotubes as self-assembling cytoskeleton mimics for synthetic cells. Expressed in vesicles from DNA templates, these RNA structures reach micrometre lengths, deform ...