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Kerstin Göpfrich

@kgoepfrich.bsky.social
2K followers 558 following 1.3K posts

Excited to engineer a synthetic cell from scratch with lipid vesicles and DNA/RNA origami-based molecular hardware. Professor @ZMBHh @UniHeidelberg

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Kerstin Göpfrich @kgoepfrich.bsky.social · 08/09/2025
Curious about RNA, aptamers, lipid membranes, molecular dynamics simulations, synthetic cells - and how these topics come together? Join @floppleton.bsky.social's talk in the unano webinar blogs.ed.ac.uk/unanowebinars
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Kerstin Göpfrich @kgoepfrich.bsky.social · 02/09/2025
RNA droplets that grow and segregate by ribozyme catalysis. Check out our latest preprint www.biorxiv.org/content/10.1101/2025.08.29.673008v1
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Kerstin Göpfrich @kgoepfrich.bsky.social · 01/08/2025
@tranmai.bsky.social handed in her PhD thesis! Celebrating in style with egg coffee from Hanoi, Mai's place of birth. P.S.: Mai is looking for a PostDoc position! Check out her latest RNA nanostructures for synthetic cells @natnano.nature.com doi.org/10.1038/s415...
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Kerstin Göpfrich @kgoepfrich.bsky.social · 28/07/2025
Preprint by @towalther.bsky.social at al! We design DNA hydrogel microparticles with sequence-controlled stiffness from 30 Pa to 6.5 kPa. They are remodelled in fibroblast spheroids www.biorxiv.org/content/10.1... Thanks @ibecbarcelona.eu @xaviertrepat.bsky.social @pcusachs.bsky.social
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Kerstin Göpfrich @kgoepfrich.bsky.social · 30/01/2025
New Master's programme in Heidelberg! Please share with interested students
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Kerstin Göpfrich @kgoepfrich.bsky.social · 27/08/2024
What happens when you apply design principles from bottom-up synthetic biology to immunology? In Heidelberg and together with @FrischknechtLab @platten_michael & Oliver Fackler we compiled the prospects of bottom-up synthetic immunology @NatureNano rdcu.be/dR0r0
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Kerstin Göpfrich @kgoepfrich.bsky.social · 09/04/2024
@ToWalther presenting our DNA microbeads that he used to generate morphogen gradients in organoids together with @AftingCassian @WittbrodtLab 🤩 @Cluster3DMM2O
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Kerstin Göpfrich @kgoepfrich.bsky.social · 03/08/2023
Hopefully they are not eaten alive on the red carpet!
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Kerstin Göpfrich @kgoepfrich.bsky.social · 02/08/2023
Fantastic talk by @CavalcantiAda at #EBSA2023 on receptor-mediated regulation of cell mechanics. Here are the references for our collaboration on the DNA nanotech tools if you want to give them a try: www.cell.com/trends/biotechnology/f…...
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Kerstin Göpfrich @kgoepfrich.bsky.social · 01/06/2023
Tomorrow we will be discussing if there are ways to make our research more sustainable. Please join us @mpi_mr_hd or via zoom: eu02web.zoom.us/webinar/register/WN… Thanks @majaillig and Jan Heidelberger for initiating this!
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Kerstin Göpfrich @kgoepfrich.bsky.social · 30/04/2023
Thank you to an anonymous reviewer who recommended this book on the origins of life. Absolutely beautifully written, captivating and full of intersting thoughts.
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Kerstin Göpfrich @kgoepfrich.bsky.social · 20/12/2022
We all like to make functional structures from DNA origami. Here is a new function by Monari et al. Thanks @monari_luca!
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Kerstin Göpfrich @kgoepfrich.bsky.social · 20/06/2022
We built DNA-based mimicks of cytoskeletal filaments capable of reversible assembly and cargo transport inside cell-sized compartments. Now out @NatureChemistry! www.nature.com/articles/s41557-022-…
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Kerstin Göpfrich @kgoepfrich.bsky.social · 31/05/2022
Dear #SynCell'ers: What would you say was the biggest breakthrough publication for the field in the past decade? We have the chance to feature it in a special issue @TrendsinBiotech. Let's decide as a community. Please RT and reply! @buildacell @SynCellEU @iGEMCommunity
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Kerstin Göpfrich @kgoepfrich.bsky.social · 11/05/2022
To the successes of the last three years! Congrats @KeJahnke! IF = %alc.
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Kerstin Göpfrich @kgoepfrich.bsky.social · 06/04/2022
3D printing goes 3D archery! @Cluster3DMM2O
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Kerstin Göpfrich @kgoepfrich.bsky.social · 25/11/2021
How can you build up structures on the inside of synthetic cells? With 3D laser printing. Very excited to share this work by @ToAbele et al @Cluster3DMM2O in Advanced Materials onlinelibrary.wiley.com/doi/abs/10.…
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Kerstin Göpfrich @kgoepfrich.bsky.social · 25/06/2021
Now @NatureComms: We realize a reaction pathway for synthetic cells that involves light-harvesting E. coli, pH-sensitive DNA origami and lipid vesicles www.nature.com/articles/s41467-021-…
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Kerstin Göpfrich @kgoepfrich.bsky.social · 31/03/2021
We find that the choice of fluorophore can alter or completely inhibit dynamics of DNA structures. Now out @NAR_Open doi.org/10.1093/nar/gkab201 @KeJahnke @max_igaev @CompBioPhys
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Kerstin Göpfrich @kgoepfrich.bsky.social · 12/03/2021
In the review, we discuss pros and cons of different membrane anchoring strategies. Check out Table 1 for guidance on the choice for specific applications authors.elsevier.com/a/1cjjPc9XEbtUM
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Kerstin Göpfrich @kgoepfrich.bsky.social · 17/02/2021
"The best way to ensure practical usefulness is not to worry about usefulness." 👇💪
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Kerstin Göpfrich @kgoepfrich.bsky.social · 28/01/2021
WANTED: A #postdoc with experience in DNA origami or high-speed AFM, data analysis & a strong interest in synthetic biology. Join a friendly & motivated group @mpi_mr_hd @Cluster3DMM2O in Heidelberg. Happy to help with fellowship applications. Please RT! www.goepfrichgroup.de
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Kerstin Göpfrich @kgoepfrich.bsky.social · 23/12/2020
Dividing christmas baubles (i.e. GUVs) and their regrowth - online just on time @angew_chem onlinelibrary.wiley.com/doi/10.1002… We divide phase-separated GUVs with enzymatic reactions or locally with light & describe the process with an analytical model....
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Kerstin Göpfrich @kgoepfrich.bsky.social · 02/10/2020
Happy birthday @Gates_Cambridge! Thank you for the support, and cheers to all friends around the world @GatesAlumni Sharing memories form the Lake District. #gatescambridge20
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Kerstin Göpfrich @kgoepfrich.bsky.social · 17/09/2020
Our IT is clearly on top of their game! @mpi_mr_hd
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Kerstin Göpfrich @kgoepfrich.bsky.social · 05/07/2020
We came a long way! @erblabs @gasb_synbio @igemmarburg
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Kerstin Göpfrich @kgoepfrich.bsky.social · 22/06/2020
I really like our new collection of historical photographs taken @mpi_mr_hd in the hallway. Thank you for putting it up! P.S.: Anyone knows what that guy is doing on the roof?
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Kerstin Göpfrich @kgoepfrich.bsky.social · 05/06/2020
The best misspelling of my last name so far!
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Kerstin Göpfrich @kgoepfrich.bsky.social · 07/05/2020
We are slowly getting ready for the post-#mpimrhomeoffice time. Our new labs are almost ready to be used!
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Kerstin Göpfrich @kgoepfrich.bsky.social · 06/05/2020
#PhotosOfMyLife Day 6/7 A picture a day for a week, no people, no explanations. I was invited by @Cluster3DMM2O
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Kerstin Göpfrich @kgoepfrich.bsky.social · 24/03/2020
A very nice bookchapter by Markvoort & Marrink that combines two of my favorite things: Lipids and acrobatics cgmartini.nl/images/stories/fusion-… Only DNA is missing!
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Kerstin Göpfrich @kgoepfrich.bsky.social · 23/03/2020
The second week of #mpimrhomeoffice. There is always the-one-experiment-you-wish-you-could-do-now - I guess scientists around the world can relate to that feeling. But health comes first. #FlattenTheCurve
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Kerstin Göpfrich @kgoepfrich.bsky.social · 13/03/2020
The group logo is in place. Soon we are ready to move into our new labs and offices @mpi_mr_hd 🧬
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Kerstin Göpfrich @kgoepfrich.bsky.social · 25/02/2020
Now @NanoLetters: We actuate plasmonic nanostructures in microfluidic compartments pubs.acs.org/doi/10.1021/acs.nanole… A collaboration between @mpi_mr_hd and @MPI_IS, feat. @M_J_Urban, Christoph Frey, Ilia Platzman, Joachim Spatz and Na Liu @UniHeidelberg...
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Kerstin Göpfrich @kgoepfrich.bsky.social · 27/01/2020
Today @mpi_mr_hd challenging me: My first talk on the blackboard! No slides at our internal #Hottop seminars.
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Kerstin Göpfrich @kgoepfrich.bsky.social · 31/12/2019
135370 Bananen bis zur Rente?! Wer hätte gedacht, das deutsche Rentenkassen Humor haben!
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Kerstin Göpfrich @kgoepfrich.bsky.social · 20/12/2019
Christmas came early: Thank you very much @CeNS_LMU for this beautiful surprise. All the best for the upcoming next decade of NanoScience!
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Kerstin Göpfrich @kgoepfrich.bsky.social · 18/12/2019
Our bookchapter is out @KeyserLab! www.springer.com/gp/book/9789811397… @SpringerNature
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Kerstin Göpfrich @kgoepfrich.bsky.social · 16/12/2019
It is good to be sperical but but better to be cylindrical, says @SchwarzUlrich at the @mattertolife Symposium - at least for fast virus uptake. Check out the papers: journals.aps.org/prl/abstract/10.11…...
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Kerstin Göpfrich @kgoepfrich.bsky.social · 15/12/2019
Joachim Spatz @mpi_mr_hd introduces the Max Planck School @mattertolife
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Kerstin Göpfrich @kgoepfrich.bsky.social · 17/07/2019
Looking for an exciting Master's programme at the interface of physics, chemistry and biology? @mattertolife @mr_mpi www.maxplanckschools.de/en/matter-t… #synbio
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Kerstin Göpfrich @kgoepfrich.bsky.social · 09/04/2019
Very nice new paper @NanoLetters by @ahcells et al: pubs.acs.org/doi/10.1021/acs.nanole… Also contains one of my favourite videos of the Spatz group - incredible how cells choose to squeeze! #mechanobiology @maxplanckpress
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Kerstin Göpfrich @kgoepfrich.bsky.social · 04/04/2019
Responive hydrogels - a powerful application of DNA nanotechnology presented by Itamar Willner #DPGR19.
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Kerstin Göpfrich @kgoepfrich.bsky.social · 09/02/2019
This is #MyResearchBuddy @MSCActions
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Kerstin Göpfrich @kgoepfrich.bsky.social · 17/01/2019
I really liked the open and collaborative peer-review platform of @FrontiersIn - almost like a chatroom where you can discuss with the authors and other reviewers. Plus: Reviews are acknowledged after publication! #openscience
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Kerstin Göpfrich @kgoepfrich.bsky.social · 11/01/2019
Today's winter seminar of Joachim Spatz' department @maxplanckpress in Stuttgart.
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Kerstin Göpfrich @kgoepfrich.bsky.social · 12/12/2018
Microscopic Christmas decoration: Our synthetic cells visualized with a confocal fluorescent microscope. @maxplanckpress @MaxSynBio #synbio
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Kerstin Göpfrich @kgoepfrich.bsky.social · 08/11/2018
Great to see the place where we have been filming with @cambridgetvnews here at #fwk18 @WGCengage
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Kerstin Göpfrich @kgoepfrich.bsky.social · 08/11/2018
Guten Morgen, Bonn! #fwk18
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Kerstin Göpfrich @kgoepfrich.bsky.social · 30/10/2018
One thing I learned during my #PhD in the UK is to carve pumpkins. Happy Halloween! #DNA
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