Intravitreal delivery of an ELOVL2 product reduces age-related molecular changes in the retina and restores visual function.

PIEZO channels are mechanosensitive ion channels conserved from plants to humans, yet structures exist for only a few mammalian orthologs. We define t…

Controlled settings may offer limited insight into the complexities of aging in natural and variable ecosystems. Artwork by Zahida Sultanova.

Natural ageing in zebrafish results in spontaneous development of valvular degeneration in both the atrioventricular (AV) and bulboventricular (BV) valves. Aged zebrafish valves are larger and exhibi...

Sickle cell disease (SCD), an inherited blood disorder caused by a mutation in the β-globin gene, is characterized by sickle erythrocytes that are ...

Have you ever wondered how your ears work? In this delightful and fascinating talk, biophysicist Jim Hudspeth demonstrates the wonderfully simple yet astonishingly powerful mechanics of hair cells, th...

A. James Hudspeth, a Rockefeller neuroscientist who discovered how sound waves are converted into electrical signals in the ear's cochlea, died Saturday at his home in Manhattan. A pioneering scientist and dedicated mentor, he was the university's F.M. ...

Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

As organisms age, somatic stem cells progressively lose their ability to sustain tissue homeostasis and support regeneration. Although stem cells are …

UC Davis faculty Sergey Stavisky, Theanne Griffith and Elisa Zhang receive prestigious early-career recognition from McKnight Endowment Fund and the Howard Hughes Medical Institute.

The authors describe a susceptibility of the peripheral nervous system to neuronal senescence with age or injury relevant for sensory dysfunction, such as chronic pain.

The heart is composed of multiple cell types, including cardiomyocytes, endothelial/endocardial cells, fibroblasts, resident immune cells and epicardi…