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Marc Chevrette

@wildtypemc.bsky.social
930 followers 325 following 96 posts

Microbiome gen(om|et)ics, secondary metabolism, comp bio, antibiotic/drug disco, evolution, & hockey. he/him.

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Reposted by Marc Chevrette
Marnix Medema @marnixmedema.bsky.social · 11/04/2026
Now out in @acs.org JACS Au, the manuscript by #BarbaraTerlouw et al. describing PARAS, a high-accuracy machine-learning algorithm to predict substrate specificities of nonribosomal peptide synthetase (NRPS) adenylation domains, key for estimating natural product structures from BGC sequence. 1/n
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Ákos T Kovács @evolvedbiofilm.bsky.social · 11/05/2026
See a brief review summarizing the use of synthetic microbial communities (SynComs) for revealing the ecology of specialized metabolites [my holiday break writing exercise] portlandpress.com/essaysbioche... #MicrobiomeEcology at Institute of Biology Leiden (IBL)
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Marc Chevrette @wildtypemc.bsky.social · 01/10/2025
On Wisconsin
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Marc Chevrette @wildtypemc.bsky.social · 15/07/2025
Bryan Cranston is Gordon Lightfoot
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Marc Chevrette @wildtypemc.bsky.social · 13/07/2025
Icon @johandelsman.bsky.social
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Reposted by Marc Chevrette
José Cediel-Becerra @jcedielbecerra.bsky.social · 08/07/2025
This is how we started implementing the similarity metric (GATOR Focal Scores) and how it actually turned out
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Reposted by Marc Chevrette
José Cediel-Becerra @jcedielbecerra.bsky.social · 08/07/2025
GATOR-GC is out at @narjournal.bsky.social!! Check out our new targeted genome mining tool featuring a novel similarity metric to efficiently compare and deduplicate gene clusters. We uncover biosynthetic diversity missed by other genome mining tools academic.oup.com/nar/article/...
academic.oup.com
Targeted genome mining with GATOR-GC maps the evolutionary landscape of biosynthetic diversity
Abstract. Gene clusters, groups of physically adjacent genes that work collectively, are pivotal to bacterial fitness and valuable in biotechnology and med
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Reposted by Marc Chevrette
Kilian Dekoninck @kdekoninck.bsky.social · 18/06/2025
#ISBA2025 will be my official introduction in the Actino community. As we all look at understanding the diversity of these Microorganisms. I remain convinced that diversity drives discovery, from natural product discovery to human community. #PrideMonth #QueerInScience
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Ákos T Kovács @evolvedbiofilm.bsky.social · 20/06/2025
Nice lunch with Bea Camara, @lore-fermar.bsky.social, @wildtypemc.bsky.social, Jordi Weijers and @evodivmet.bsky.social (not on photo) discussing microbes and their interactions #InternationalScience
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Ákos T Kovács @evolvedbiofilm.bsky.social · 24/05/2025
Distinguishing among evolutionary and ecological processes shaping microbiome dynamics #ISMEJournal review by Tiffany N Batarseh and @bkoskella.bsky.social academic.oup.com/ismej/advanc...
academic.oup.com
Distinguishing among evolutionary and ecological processes shaping microbiome dynamics
Abstract. Evolution is defined as the change in allele frequency over time as a result of either neutral processes, such as genetic drift, or as an adaptiv
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Marc Chevrette @wildtypemc.bsky.social · 24/05/2025
If you are a PhD student in microbial interactions or natural products that is displaced by this political bullshit and looking for a new lab, I have room for one (or potentially two) PhD students in my group in the fall when I move to UW. Feel free to reach out via email.
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Reposted by Marc Chevrette
karl rove knausgård @uhactually.bsky.social · 27/04/2025
In other words, when you ask for example “do vaccines cause autism?” you are looking for information about whether a thing in the world (a vaccination) produces an outcome (autism). But the LLM can only answer “what words could sound right after this?”
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Marc Chevrette @wildtypemc.bsky.social · 27/04/2025
antiSMASH8: The Ocho Manuscript is out! doi.org/10.1093/nar/...
doi.org
antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation
Abstract. Microorganisms synthesize small bioactive compounds through their secondary or specialized metabolism. Those compounds play an important role in
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Reposted by Marc Chevrette
cemist.bsky.social @cemist.bsky.social · 14/04/2025
CeMiSt affiliated Caja Dinesen defended her PhD "Microbial signaling and secondary metabolites" Congratulations! With examiners Thomas Tørring @thomastorring.bsky.social, Lone Gram @lonegram.bsky.social, co-supervisor Thomas Ostenfeld Larsen, and supervisor Ákos T. Kovács@evolvedbiofilm.bsky.social.
Caja Dinesen with examiners Thomas Tørring, Lone Gram, co-supervisor Thomas Ostenfeld Larsen, and supervisor Ákos T. Kovács.
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Josh Kellogg @kelloggnpgroup.bsky.social · 14/04/2025
All our #secmet and #ethnobotany people should come spread your #botany knowledge this summer!!
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Reposted by Marc Chevrette
Brian O. Bachmann @brianobachmann.bsky.social · 04/04/2025
We put together this protocol in part to encourage broader adoption of Multiplexed Activity Metabolomics, an engine for functional metabolomics of all types including specialized metabolite discovery. We enjoy knowing if metabolite is active before isolating it, and so should you! #natprod
sciencedirect.com
Multiplexed cytometry for single cell chemical biology
Flow cytometry has great potential for screening in translational research areas due to its deep quantification of cellular features, ability to colle…
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Marc Chevrette @wildtypemc.bsky.social · 02/04/2025
Well done, Wisconsin thehill.com/homenews/cam...
thehill.com
Liberal candidate wins Wisconsin Supreme Court race in blow to Trump, Musk
Susan Crawford was projected to win an open seat on the Wisconsin Supreme Court race, keeping the high court’s 4-3 liberal majority intact and delivering a blow to Elon Musk and President Trump, ac…
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Marc Chevrette @wildtypemc.bsky.social · 30/03/2025
The Chevrette Lab has some big news. Beginning in August we'll be joining @uwmadscience.bsky.social in the Department of Plant Pathology and @widofficial.bsky.social Beyond excited for this new chapter. youtu.be/t-M09m-y1KU?...
youtu.be
Kenny Chesney - Back Where I Come From (Live at Farm Aid 2005)
YouTube video by Farm Aid
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Reposted by Marc Chevrette
Kristen DeAngelis 🏳️‍🌈🏳️‍⚧️🍉 @kristenobacter.bsky.social · 21/03/2025
A message sent to tonight to all UMass faculty reminding us that we sacrifice 1st and 4th amendment rights when we travel internationally, and warning that non-citizens put themselves at risk when traveling. I’m glad for the warning & but pissed that this is where we’re at.
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Marc Chevrette @wildtypemc.bsky.social · 21/03/2025
New preprint collab with the Zhou lab! www.biorxiv.org/content/10.1... Learning gene interactions and functional landscapes from entire bacterial proteomes
biorxiv.org
Learning gene interactions and functional landscapes from entire bacterial proteomes
Unraveling complex gene interactions and understanding their functions in the genomes of bacteria will provide critical advancements in fields including bacterial genome evolution, microbiome studies,...
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Reposted by Marc Chevrette
Natural Product Reports @natprodreports.rsc.org · 17/03/2025
🎉We are delighted to welcome @tilmweber.bsky.social from the Technical University of Denmark to the @natprodreports.rsc.org Editorial Board! Learn more about Tilmann here🔽 blogs.rsc.org/np/2025/03/1...
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Mark O. Martin @markowenmartin.bsky.social · 15/03/2025
I don't usually get much email about my #MattersMicrobial podcast, which is okay. But I had a PhD student in Brazil just write to me, thanking me for a prior podcast I did with @wildtypemc.bsky.social on genome mining, which she found useful. That made me happy.
media.tenor.com
a man with a mustache says how bout that in blue
ALT: a man with a mustache says how bout that in blue
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Marc Chevrette @wildtypemc.bsky.social · 15/03/2025
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Marc Chevrette @wildtypemc.bsky.social · 12/03/2025
Anyone have a good way to bulk backup a full Outlook 365 email account (with attachments)?
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Reposted by Marc Chevrette
Paul Fairie @paulisci.bsky.social · 12/03/2025
August 2014:
Obama's tan suit topic of Thursday
--The News Tribune, 31 Aug 2014
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Wisconsin Institute for Discovery @widofficial.bsky.social · 10/03/2025
Congratulations to Claudia Solís-Lemus! The Bassam Z. Shakhashiri Public Science Engagement Award recognizes one University of Wisconsin–Madison faculty member and one academic staff member for excellence in engaging the public with STEAM (Science, Technology, Engineering, Arts, and Math) research.
Wisconsin Institute for Discovery congratulates Claudia Solís-Lemus, 2025 winner of the Bassam Z. Shakhashiri Public Science Engagement Award. Photo of Dr. Solís-Lemus. Story at https://research.wisc.edu/uncategorized/2025/03/05/excellence-in-outreach-recognized-with-bassam-z-shakhashiri-public-science-engagement-award-2/
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Marc Chevrette @wildtypemc.bsky.social · 07/03/2025
Nice little Friday
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Dan Udwary @danudwary.secondarymetabolism.com · 05/03/2025
Preprint for @wildtypemc.bsky.social 's GATOR-GC is out! Have been looking forward to using this to explore secondary metabolite BGCs! www.biorxiv.org/content/10.1...
biorxiv.org
Targeted genome mining with GATOR-GC maps the evolutionary landscape of biosynthetic diversity
Gene clusters, groups of physically adjacent genes that work collectively, are pivotal to bacterial fitness and valuable in biotechnology and medicine. While various genome mining tools can identify a...
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Reposted by Marc Chevrette
Jeremy Berg @jeremymberg.bsky.social · 01/03/2025
Extending my grant update this morning. Here are data limited to new and competitive renewal applications. The Pause is dead, Long live the Pause...
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Reposted by Marc Chevrette
Paco Barona Gomez @evodivmet.bsky.social · 28/02/2025
This is a game changer .... Will hardly look back after using it!
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Marc Chevrette @wildtypemc.bsky.social · 28/02/2025
GATOR-GC preprint is live! If you haven't already, check out our new tool for targeted gene cluster mining. @jcedielbecerra.bsky.social doi.org/10.1101/2025...
doi.org
Targeted genome mining with GATOR-GC maps the evolutionary landscape of biosynthetic diversity
Gene clusters, groups of physically adjacent genes that work collectively, are pivotal to bacterial fitness and valuable in biotechnology and medicine. While various genome mining tools can identify a...
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Reposted by Marc Chevrette
Evelyndroid's Aperture Science and Bugge-Finding 🏳️‍⚧️🕷️ @apsciencebylyn.bsky.social · 29/07/2024
Pseudomyrmex gracilis is an ant species I'm sure many of you have seen before. They're kinda badass in their own way; large, very good vision and awareness, and more than capable of defending themselves (and stinging). Tutelina lass does not care. They are ant, and therefore prey. 🌿 🕷️ 🧪
Small purple-ish jumping spider with orange legs; feeding on a large slender grey and red ant as she peers at you from a green oak leafTop view of the shiny lass, with the comically large ant in her grasp
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Marc Chevrette @wildtypemc.bsky.social · 27/02/2025
A large part of what we chatted about comes from the awesome work of @cumsille.bsky.social. Check it out!
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Reposted by Marc Chevrette
Mark O. Martin @markowenmartin.bsky.social · 27/02/2025
Thursday: time for #MattersMicrobial Episode #81! Dr. Marc Chevrette talks about genome mining, secondary metabolites, and why microbes are the very best chemists. Please share the #GoodMicrobialWord. @profvrr @wildtypeMC youtu.be/QYGiAc4lRsk?...
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Marc Chevrette @wildtypemc.bsky.social · 22/02/2025
Movie you've watched more than 6 times, gifs only
media.tenor.com
a man in a sweater says sorry guys i gotta see about a girl .
ALT: a man in a sweater says sorry guys i gotta see about a girl .
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Marc Chevrette @wildtypemc.bsky.social · 21/02/2025
Out today in Angewandte Chemie Evolution-Guided Discovery of Antimycobacterial Triculamin-Like Lasso Peptides doi.org/10.1002/anie... Fun collaboration with the Tørring lab @thomastorring.bsky.social @tizianasvenningsen.bsky.social @amerrild.bsky.social
doi.org
Evolution‐Guided Discovery of Antimycobacterial Triculamin‐Like Lasso Peptides
Triculamin is a ribosomally synthesized and post-translationally modified peptide (RiPP) lasso peptide with potent antimycobacterial activity, produced by an unusual, non-canonical biosynthetic gene ...
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Marc Chevrette @wildtypemc.bsky.social · 21/02/2025
What the shit "For FY26 we are told about plans to reduce the NSF budget by 50%-75% - such reduction will mean no new awards for at least a year, elimination of divisions, merging of programs." nanoscale.blogspot.com/2025/02/the-...
nanoscale.blogspot.com
The National Science Foundation - this is not business as usual
The National Science Foundation was created 75 years ago, at the behest of Vannevar Bush , who put together the famed study, Science, The E...
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Mark O. Martin @markowenmartin.bsky.social · 20/02/2025
Really fun podcast with Marc Chevrette on genomic mining and why microbes are the very best chemists. @wildtypemc.bsky.social
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Marc Chevrette @wildtypemc.bsky.social · 20/02/2025
Matters Microbial Podcast recording done! Thanks @markowenmartin.bsky.social for the invite to share a little of our work and chat mining microbial genomes/interactions.
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Marc Chevrette @wildtypemc.bsky.social · 20/02/2025
perl -p -i -e 's/(\$\d+)M/${1} .B/g' doge.csv
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Ákos T Kovács @evolvedbiofilm.bsky.social · 18/02/2025
Gaining insights into the complexity of specialized metabolites and their possible ecological roles These metabolites not only function as antimicrobials, but also as cue molecules among other peculiar functions -see our paper in microLIFE of @femsjournals.bsky.social on surfactin and subtilosin A
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Jo Handelsman, PhD @johandelsman.bsky.social · 13/02/2025
"Make America Great Again. Make America Healthy Again. These were promises made by candidate Trump in his campaign to be president of the United States of America. What in this campaign platform should have prepared us for a war on discovery?"
wisconsintechnologycouncil.com
Guest column: “The war on discovery” is antithesis of campaign pledge to make America great again - Wisconsin Technology Council
By Jo Handelsman MADISON, Wis. – Make America Great Again. Make America Healthy Again. These were promises made by candidate Trump in his campaign to be president of the United States of America. What...
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Marc Chevrette @wildtypemc.bsky.social · 13/02/2025
"This is the time for all citizens, scientists, the executive branch and Congress to join forces and strengthen the research engine." - @johandelsman.bsky.social wisconsintechnologycouncil.com/guest-column...
wisconsintechnologycouncil.com
Guest column: “The war on discovery” is antithesis of campaign pledge to make America great again - Wisconsin Technology Council
By Jo Handelsman MADISON, Wis. – Make America Great Again. Make America Healthy Again. These were promises made by candidate Trump in his campaign to be president of the United States of America. What...
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Marc Chevrette @wildtypemc.bsky.social · 11/02/2025
22 states starting the IDC legal battle AZ, CA, CO, CT, DE, HI, IL, MA, ME, MD, MI, MN, NC, NJ, NM, NV, NY, OR, RI, VT, WA, WI www.statnews.com/2025/02/10/n...
statnews.com
Federal judge halts Trump administration cuts to NIH research payments in 22 states
Attorneys general sued the Trump administration to block a NIH decision that would slash grant payments for research overhead
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Loic Lepiniec @lepiniec.bsky.social · 06/02/2025
Multi-omic analyses unveil contrasting composition and spatial distribution of specialized metabolites in seeds of Camelina sativa and other Brassicaceae pubmed.ncbi.nlm.nih.gov/39908193/
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Grace Thoburn @gracethoburn.bsky.social · 04/02/2025
We're delighted to announce Fidele Ntie-Kang (University of Buea) as the winner of the 2025 Natural Product Reports Emerging Investigator Lectureship! 🎉 Read more about Fidele and his research here: blogs.rsc.org/np/2025/02/0... #NatProd #PlantScience
Graphic announcing Fidele Ntie-Kang as the Lectureship winner.
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Marc Chevrette @wildtypemc.bsky.social · 06/02/2025
Julian is truly one of the great minds of our time. His work inspires everything I do in my own. I consider myself very lucky for having met him briefly and to have sat in on many a seminar.
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Marc Chevrette @wildtypemc.bsky.social · 31/01/2025
Manuscript submitted. I declare this week officially over.
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Dr Craig R McClain @drcraigmc.bsky.social · 29/01/2025
Somewhere in the U.S., there’s a scientist staring at their NSF/NIH grant application wondering why they bother. This post is for you. Science and society both need you. Hang in there and know there is a whole community supporting you.
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Marc Chevrette @wildtypemc.bsky.social · 21/01/2025
UF just canceled classes tomorrow because of the cold. It's 43F (6C).
media.tenor.com
Bane Batman GIF
ALT: Bane Batman GIF
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