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Thomas Tørring

@thomastorring.bsky.social
778 followers 422 following 14 posts

Assoc. Prof @ Aarhus Uni. Interested in natural prod, antibiotic, microbiology, chemical biology and fermented food.

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Reposted by Thomas Tørring
Nadine Ziemert @nadineziemert.bsky.social · 13/05/2025
Happy to announce that our „newest old tool“ autoMLST2.0 is out and published. You need an accurate and easy to use tool to build #phylogenetictrees from #bacterialgenomes: academic.oup.com/nar/advance-...
academic.oup.com
AutoMLST2: a web server for phylogeny and microbial taxonomy
Abstract. Accurate and accessible phylogenetic analysis is essential for understanding microbial taxonomy and evolution, which are integral to microbiology
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Reposted by Thomas Tørring
Christopher Whitford @chriiswh.bsky.social · 27/03/2025
Interested in engineering streptomycetes? Struggling with existing genome engineering tools? Then check out our newest paper on CASCADE-Cas3 based genome engineering in streptomycetes! Some highlights below:
academic.oup.com
CASCADE-Cas3 enables highly efficient genome engineering in Streptomyces species
Abstract. Type I clustered regularly interspaced short palindromic repeat (CRISPR) systems are widespread in bacteria and archaea. Compared to more widely
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Reposted by Thomas Tørring
Chekan Lab @chekanlab.bsky.social · 16/01/2025
We are excited to see our review published! In it, we explore the diversity of enzymatic strategies for installing aromatic side chain cross-links in RiPPs. If you like interesting chemistry and new enzyme reactions, be sure to check it out!
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Reposted by Thomas Tørring
Marc Chevrette @wildtypemc.bsky.social · 12/01/2025
~5y ago, Barbara, Serina, @marnixmedema.bsky.social & I teamed up to make a better NRPS A-domain specificity predictor. The Challis group & others joined along the way to add some very cool insights. Very proud of this work. Check it out now on biorxiv! doi.org/10.1101/2025...
doi.org
PARAS: high-accuracy machine-learning of substrate specificities in nonribosomal peptide synthetases
Nonribosomal peptides are chemically and functionally diverse natural products with important applications in medicine and agriculture. Bacterial and fungal genomes contain thousands of nonribosomal p...
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Reposted by Thomas Tørring
Marc Chevrette @wildtypemc.bsky.social · 22/12/2024
Just in time for the holidays Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin www.biorxiv.org/content/10.1... @amerrild.bsky.social @tizianasvenningsen.bsky.social @thomastorring.bsky.social
biorxiv.org
Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin
Triculamin is a ribosomally synthesized and post-translationally modified peptide (RiPP) lasso peptide with potent antimycobacterial activity, produced by an unusual, non-canonical biosynthetic gene c...
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Reposted by Thomas Tørring
Brian O. Bachmann @brianobachmann.bsky.social · 20/12/2024
Interesting tool alert. The thing that makes this look promising is a way to "plasmidify" biosynthetic gene clusters in their native producers. Could simplify refactoring and expression in chassis strains. #secmet www.science.org/doi/10.1126/...
science.org
Autologous DNA mobilization and multiplication expedite natural products discovery from bacteria
The transmission of antibiotic-resistance genes, comprising mobilization and relocation events, orchestrates the dissemination of antimicrobial resistance. Inspired by this evolutionarily successful p...
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Thomas Tørring @thomastorring.bsky.social · 22/12/2024
A Christmas present to all of the lasso peptide connoisseurs out there. The next chapter in our work is on triculamin is ready on bioRxiv. Great work by two incredibly talented graduate students @amerrild.bsky.social and @tizianasvenningsen.bsky.social. www.biorxiv.org/content/10.1...
biorxiv.org
Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin
Triculamin is a ribosomally synthesized and post-translationally modified peptide (RiPP) lasso peptide with potent antimycobacterial activity, produced by an unusual, non-canonical biosynthetic gene c...
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Reposted by Thomas Tørring
Marc Chevrette @wildtypemc.bsky.social · 19/12/2024
Adam Rivers (USDA-ARS) and I are hiring a joint postdoc to on a microfluidics and sequencing based project to better understand synthetic and natural microbiome community dynamics and generate data to build AI/ML models to infer interspp. interactions. Hit me up if interested!
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Reposted by Thomas Tørring
Mitja M. Zdouc @mmzdouc.bsky.social · 10/12/2024
Are you working on natural products? We’ve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...
academic.oup.com
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration
Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag
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Thomas Tørring @thomastorring.bsky.social · 11/11/2024
Early morning and on my way to Copenhagen for the 2024 Congress in the Danish Microbiological Society #DMS2024. Looking forward to seeing friends - old and new.
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Reposted by Thomas Tørring
Kai Blin @kblin.bsky.social · 04/12/2023
Hey Natural Products folks! Do you have a favourite ontology covering natural product bioactivities? I'm trying to make MIBiG a bit more systematic for the next release and would like to avoid creating a separate ontology if at all possible. #secmet #microsky
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Thomas Tørring @thomastorring.bsky.social · 17/11/2023
For teaching purposes, I am looking for culture collection strains that consistently produce a known antibiotic like vancomycin , erythromycin, daptomycin or similar. Any suggestions? I’d prefer NRRL or DSMZ
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Reposted by Thomas Tørring
Brian O. Bachmann @brianobachmann.bsky.social · 15/10/2023
#secmet folks : a teach-in in honor of Chris Walsh. All students and post-docs encouraged to attend. This is an outstanding speaker list inspired a great scientist & teacher.
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Reposted by Thomas Tørring
Dan Udwary @danudwary.secondarymetabolism.com · 05/10/2023
Now releasing into your podcast feeds: JGI's Natural Prodcast talks to Alison Narayan (UMich) about biocatalysis and candy corn! Notes and transcripts (and in-browser audio) at naturalprodcast.com 🧪🧬🖥️ #chemsky
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Thomas Tørring @thomastorring.bsky.social · 05/10/2023
A good book, a cup of coffee, and PJ Harvey. This morning is off to a start
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Thomas Tørring @thomastorring.bsky.social · 05/10/2023
Looking forward to reading this one
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Thomas Tørring @thomastorring.bsky.social · 24/09/2023
On the train to Copenhagen for the iimena symposium. Looking very much forward to two days of #naturalproducts
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Reposted by Thomas Tørring
Dr Katherine Duncan @kateduncan.bsky.social · 23/09/2023
Come work with us!! Lecturer / Senior Lecturer in Antimicrobial Drug Discovery at Newcastle University @nubiosciences! Please RT #AMR #DrugDiscovery #NaturalProducts #Metabolomics #Microbiology www.jobs.ac.uk/job/DCX827/l...
jobs.ac.uk
Lecturer/ Senior Lecturer in Antimicrobial Drug Discovery at Newcastle University
Recruiting now: Lecturer/ Senior Lecturer in Antimicrobial Drug Discovery on jobs.ac.uk. Click for details and explore more academic job opportunities on the top job board
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