Covering: 2013–2024 Benefiting significantly from recent advances in genome mining, ribosomally synthesized and posttranslationally modified peptide (RiPP) natural products have emerged as a source…

Covering: up to 2025 Natural product-based research encompasses the discovery, structure elucidation, biosynthesis, synthesis, and application of naturally occurring secondary metabolites.…

Covering: 1974 to 2024 Human microbiota consist of a diverse array of microorganisms, such as bacteria, Eukarya, archaea, and viruses, which populate various parts of the human body and live in ...

This kit provides the tools for everyone to take part in positive change: employers, colleagues, and LGBT+ individuals.

Covering 1948 up to October 2024 Sorbicillinoids are a growing class of natural products (NPs) that stem from a variety of fungi including members of the orders Hypocreales and Eurotiales. This…

Covering: 2012 to 2024 Isoflavonoids are phenolic compounds with wide structural diversity and a plethora of biological activities. Owing to their structural variation and potential health-promoting…

Covering: up to 2025 Crystallographic analysis has become the most reliable method for elucidating the structures of natural products, as it can provide absolute configurations with precise spatial…

Natural products have applications as biopharmaceuticals, agrochemicals, and other high-value chemicals. However, there are challenges in isolating natural products from their native producers (e.g. b...

Viral infections trigger the integrated stress response (ISR) in eukaryotic cells that leads to the activation of eIF2α kinases, the elevation of eukaryotic translation initiation factor 2α (eIF2α)…

An imine derived from 4-(N,N-dimethylamino)benzaldehyde and a primary amine undergoes very rapid hydrolysis in weak acid, however, it can be encapsulated within cucurbit[7]uril (CB7) to give a…

Covering: up to 2024. For many years, the value of complex polyketides lay in their medical properties, including their antibiotic and antifungal activities, with little consideration paid to their…

Tracking nanoparticles’ location is imperative for understanding cellular interactions, pharmacokinetics, and biodistribution. DiD is a lipophilic dye commonly used to label nanoparticles for traffick...

Covering: up to the end of 2024 Breastfeeding is one of the most effective ways to promote child health. However, characterizing the chemistry that fortifies the benefits of breastfeeding remain...

Covering: January to the end of December 2023 This review covers the literature published in 2023 for marine natural products (MNPs), with 582 citations (541 for the period January to December 2...

Traditional small molecule drugs often target protein activity directly, but challenges arise when proteins lack suitable functional sites. An alternative approach is targeted protein degradation…

SFM4-3, KOD DGLNK, and Therminator polymerase are investigated for their compatibility with SELection with Modified Aptamers (SELMA), an aptamer discovery method that enables incorporation of large nu...

A personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products, such as hyperzrone A from Hypericum beanii.

Dwellings across the United States range dramatically with respect to numerous variables (e.g., size, ventilation, and proximity to outdoor sources), and there are considerable uncertainties regarding...

In the past decade, interest in nanoplasmonic structures has experienced significant growth, owing to rapid advancements in materials science and the evolution of novel nanofabrication techniques. The...

Covering 1948 up to October 2024Sorbicillinoids are a growing class of natural products (NPs) that stem from a variety of fungi including members of the orders Hypocreales and Eurotiales. This compoun...

A biotinylated helical aromatic oligoamide foldamer equivalent in size to a 24mer peptide was designed without any prejudice other than to display various polar and hydrophobic side chains at its surf...

Covering: 2019 to 2024Secondary metabolites (SMs) are naturally occurring defense or signaling molecules that are also utilized as human and animal drugs, crop protection agents, and fine chemicals. C...

Covering: January to the end of December 2023 This review covers the literature published in 2023 for marine natural products (MNPs), with 582 citations (541 for the period January to December 2...

Labour appears to have dropped the Conservative government’s pledge to place accessibility right at the heart of the new national body that will run the railways. Concerns were raised by The Associ…