iiinova — where your digital self keeps evolving

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Kyle Swanson, MD, FAANS, FCNS @kiswanson.medsky.network · 22h

I have not watched any of the other Packer games this season besides this game against the Bears…I will assume we are the best team in the nfl

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Jessica Tollkuhn @tollkuhn.bsky.social · 10/10/2026

junior faculty really need to understand that at least one of their grant reviewers will not be in their field, and may potentially not be familiar with the system or techniques in the application.

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Ed Zitron @edzitron.com · 08/10/2026

According to sources familiar with the matter, someone made up the numbers entirely, and uhhh,,,,,,,,

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According to a person with knowledge of the matter, the discrepancy arose from attempts by OpenAI’s own investors to produce a direct comparison with Anthropic’s annualised revenues. The pair calculate the figure in different ways, with Anthropic including the revenue from sales via cloud partners such as AWS and Google Cloud, while OpenAI does not.

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Kip Ludwig @wildpiguk.bsky.social · 07/10/2026

Given Retrosense’s IP was acquired on the cheap after their unpublished Phase I results, seems like the first attempt in the 2010s didn’t go so well.

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 06/10/2026

Earlier this year the scientific community successfully fought back on dramatic changes in Federal funding proposed by the Trump Administration.Now another RFI is proposing substantial changes that would damage peer review. This letter from SDB President Helen McNeill lays out the issue clearly 1/n

Dear SDB Members,

I am writing you now to ask everyone to respond to a proposed change to the way that grant review information at the National Institutes of Health (NIH) is communicated to grant applicants, institutions, and NIH program staff. This is your opportunity to provide feedback on the process that selects our grants for funding.

The proposed change means that individuals, institutes and NIH staff will no longer receive the final overall impact score or percentile score that reflects the scientific opinion of a panel of experts. Currently, three reviewers provide their detailed opinion of a grant, and then the entire panel asks questions, can examine figures, and discuss the strengths and weaknesses of a grant, and then members all independently score. The final overall impact score reflects this discussion and careful consideration of the entire scientific panel.

The proposed change is to now simply divide the scored grants into three categories: Scored applications would be grouped into three broad categories - “Most Competitive (top 25%),” “Competitive (26%-50%),” and “Not Discussed”. The motivation for the change is that decisions would now focus on the comments of reviewers, not the score of the grant to determine which grants to support. However, the current mechanism allows for scores and comments to be considered. Thus, removing the score component from NIH staff makes selection of which grants to fund more burdensome for NIH staff.

The loss of detailed scores will also make it more difficult for researchers to assess how competitive an application was and determine whether to revise and resubmit it. An application ranked top 2% and one ranked 24th% would receive the same label, even if the scientific panel viewed them quite differently. Meanwhile, applications ranked 25th%and 26th% would be placed in different categories because of a tiny difference that NIH itself says should not be treated as meaningful. The proposal would erase potentially important differences while creating arbitrary new dividing lines.

This is a dramatic loss of transparency in the scientific review process. Under the new plan, principal investigator(s), applicant institutions, NIH program staff, ICO leadership, and the relevant NIH Advisory Council will no longer have access to the final overall score.

NIH is explicitly asking for input on this particular question.

This is a Request for Information (RFI), not simply an announcement of a policy that has already been finalized. NIH says comments will be used to inform the final recommendation, including implementation and communication.

Please comment here: https://rfi.grants.nih.gov/?s=6a2b1c22c3fcfda46e0badd2

Deadline for response receipt is October 13, 2026, 11:59 PM ET.

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Mark Histed @markhisted.org · 05/10/2026

Oh I shd add: Deisseroth’s work was (say it w me!) supported with public funding through federal science agencies incl NIH, NSF, and DARPA. And I daresay few political deciders in 2004 would have been excited to put algal proteins in HEK cells or neurons. Scientists knew, though.

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Naveen from Neurotech Futures @neurotechnology.substack.com · 04/10/2026

Neurotech Job seekers: We relaunched neurotechjobs.io! New site, with a new newsletter coming soon. Share your perspective and please share with your colleagues looking for work in this field! forms.gle/MokuufDEKXyo...

forms.gle

Working In Neurotech: Community Survey

Hello! Neurotech Futures is shaping the future of our job board and newsletter. I'm asking for YOUR help as a member of our ecosystem. Please share some quick input with us to help us ensure our work...

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The vOICe vision BCI 🧠🇪🇺 @seeingwithsound.bsky.social · 01/10/2026

#Neuralink on representational drift (until recently): "Users spend an average of 55 minutes per week calibrating simply to maintain control." neuralink.com/updates/pret... "Calibrating each decoder to peak performance could take the better part of their mornings." #BCI #NeuroTech

neuralink.com

Pretraining on 50,000 Hours of Unlabeled Brain Data

How self-supervised encoders kept neural decoders working for weeks without recalibration and set an 11.32 BPS record.

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Reza Shadmehr @rezashadmehr.bsky.social · 22/09/2026

Faculty position opening in computational neuroscience at Duke University. academicjobsonline.org/ajo/jobs/32697

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TK (Takashi DY) Kozai @bioniclab.bsky.social · 21/09/2026

www.reddit.com/r/NIH/s/WdDl...

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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 21/09/2026

The person who thinks that he has the ability to decide which science to fund out of hundreds of subfields is exactly the person who should not make that decision. There is a reason that expert committees of scientists review and give recommendations for funding. No one person can know all of it.

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Tobias Egner @tobiasegner.bsky.social · 18/09/2026

Job Alert: Our department is looking to recruit an eminent scholar for a distinguished, endowed professorship (full professor, tenured) in the domain of human neuroscience with high clinical relevance. Please broadcast widely! For application information, see academicjobsonline.org/ajo/jobs/32753

academicjobsonline.org

Duke University, Psychology and Neuroscience

Job #AJO32753, Professor (tenured), Psychology and Neuroscience, Duke University, Durham, North Carolina, US

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The vOICe vision BCI 🧠🇪🇺 @seeingwithsound.bsky.social · 06/09/2026

(LinkedIn) Intracortical microstimulation (#ICMS) patterns affect cell-specific myelination, so myelin insulation is not a fixed given in brain stimulation www.linkedin.com/posts/tkozai... "Oligodendrocytes respond to the pattern of the pulses"; by @bioniclab.bsky.social on #BCI #neuroscience

linkedin.com

Takashi (T.K.) Kozai | Substack | TK Kozai

🎉 Camila Garcia Padilla is now principal investigator on her own NIH grant. NINDS issued the Notice of Award for her F31 in August 2026 (F31NS147846) (she joined the lab 2022, as an ARCS Scholar). 🧠 ...

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Kip Ludwig @wildpiguk.bsky.social · 05/09/2026

I’ve been listening to the #Beatles albums in order to pass time during cardio workouts. I love them, but if you are killing yourself near the end of a #workout, having ”I‘m So Tired” from the #WhiteAlbum come on unexpectedly may be the worst pump up song ever.

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Kip Ludwig @wildpiguk.bsky.social · 05/09/2026

I understand your point of view. I’m a fast reader, but I’m still out after the first blatant factual error that isn’t really debatable. Too much to read in neurotech to keep going if I see at any point they aren’t doing their research.

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Kip Ludwig @wildpiguk.bsky.social · 03/09/2026

The most problematic and effective liars sprinkle in facts to make their bs less obvious. That doesn’t mean it’s still not misleading hype ignoring facts.

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Kip Ludwig @wildpiguk.bsky.social · 03/09/2026

I made the mistake of looking at the blog. Stopped reading after factual errors in the first bit blatant to anyone knows the history of neuroprosthetics It’s sad because they lose all scientific credibility with the false hype ‘first to‘ bullshit, and I know people there who know it’s BS.

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Kip Ludwig @wildpiguk.bsky.social · 28/08/2026

By the power vested in me by my old Blockbuster video rental card, I officially rename the #WhiteHouse La Maison De Douchebag.

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Society for Neuroscience @sfn.org · 21/08/2026

Scientific peer review must remain the primary foundation of NIH funding. SfN is concerned about NIH's proposed changes to grant review and funding decisions. Read our statement: vist.ly/5fpaa

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Kip Ludwig @wildpiguk.bsky.social · 03/08/2026

I am hereby exclusively calling #LLM based #AI word guessing programs. #dontbelievethehype

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Kip Ludwig @wildpiguk.bsky.social · 02/08/2026

And for some reason, almost always on a Sunday to be share widely before the stock market opens on Monday. Major offensives come after wall street closing on Friday.

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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 29/07/2026

I’m one of 155 physicians & scientists who signed this open letter calling on elected officials to end the vilification & harassment of scientists like Peter Hotez & Anthony Fauci We urge them to “stop these witch-hunts” www.medpagetoday.com/washington-w...

medpagetoday.com

Stop 'Harassment' of Fauci, Scientists Urge Politicians

Open letter signed by 155 physicians, scientists ahead of Congressional testimony

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Mark Histed @markhisted.org · 24/07/2026

I co-sign this great summary from @dereklowe.bsky.social . The goal is to destroy academic science, and these are the reasons. And all the “gold standard” and “needs reform” and “not high risk” stuff is transparent bullshit to hide the ball on what they are doing.

=
Science
science. But let me make something clear right up front. When I talk to people about this subject (and that includes some journalists as well) and say what I'm about to at the end of this paragaph I am sometimes met with disbelief. But I mean what I say and I am trying my best to say what I mean: The Trump administration hates academic science funding, full stop. They hate where that money goes, and they hate who it goes to. They want to keep all that money for themselves, to hand out to favored cronies who can help them get elected and to steer yet more money and more power back into their hands.
That's it. That's the story. They are naturally not putting it in those words, but instead talking about "gold standard science" and the
"reproducibility crisis" and funding "bold inquiry" for "transformational
breakthroughs". This is all bullshit, and it's important to realize that. Shameless hand-waving bullshit, delivered in a how-dare-vou-

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Mark Histed @markhisted.org · 23/07/2026

100% on target—this is the way to think about the Trump science plan.

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The vOICe vision BCI 🧠🇪🇺 @seeingwithsound.bsky.social · 16/07/2026

Long-term safety and efficacy of intracortical microstimulation in humans www.science.org/doi/10.1126/... "electrodes maintained sufficient activity for 2 to 10 years; #ICMS #BCI #NeuroTech

science.org

Long-term safety and efficacy of intracortical microstimulation in humans

Intracortical microstimulation in humans is safe and efficacious for up to 10 years.

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Mark Histed @markhisted.org · 11/07/2026

“if I was trying to ruin American leadership in scientific research this is pretty much the kind of rule I would write.” Worth reading the whole thing from @dandrezner.bsky.social . I have two things to add to what he says: 1/

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Kip Ludwig @wildpiguk.bsky.social · 12/07/2026

I’ve just come to the shocking self-realization that both my science and comedy writing are essentially the same thing. I bluntly say a bunch of blatantly obvious things that for whatever reason people have sub consciously avoided thinking about. Ironically, I never caught that before myself.

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Kip Ludwig @wildpiguk.bsky.social · 12/07/2026

It also requires a much better business case.

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Kip Ludwig @wildpiguk.bsky.social · 10/07/2026

Regardless of party, can we all agree not to support very bad people? The #whataboutism has got to stop. #goodpeopleoverparty

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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 06/07/2026

www.nytimes.com/2026/07/06/u... an ominous trend: graduate admissions are down 15 percent from last year, on top of an 11 percent decrease from the previous year we are destroying our seed corn

nytimes.com

Research Universities Are Admitting Fewer Ph.D.s, a Bad Sign for Science

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Kip Ludwig @wildpiguk.bsky.social · 29/06/2026

“Our study reveals prevalent brittleness in the presence of simple adversarial transformations: leading systems can guess the correct answer even with key inputs removed yet may get confused by the slightest prompt alterations…” #AI www.nature.com/articles/s41...

nature.com

Evaluating the robustness and readiness of large frontier models in health AI applications - Nature Medicine

Adversarial evaluation of leading AI models uncovers gaps between benchmark success and robustness, highlighting limitations in current health AI benchmarks and their ability to capture clinically rel...

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TK (Takashi DY) Kozai @bioniclab.bsky.social · 26/06/2026

Roughly half of intracortical microelectrodes lose recording capability within a year of implantation. The B.I.O.N.I.C. Lab at Pitt is hiring a postdoc to attack the mechanism on two parallel grant-funded threads. 🧵 (1/7)

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Kip Ludwig @wildpiguk.bsky.social · 18/06/2026

Seen on the wall at a local bar:

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Eric Topol @erictopol.bsky.social · 15/06/2026

A @nejm.org editorial today on the Office of White House Management and Budget (OMB) regarding their new funding proposal and politicization of science www.nejm.org/doi/full/10....

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Kip Ludwig @wildpiguk.bsky.social · 06/06/2026

I keep seeing how #Elon #Musk will be the world's first trillionaire with the SpaceX IPO. If you take the value of all wealth and assets, the whole world is estimated at ~450 trillion dollars. There are ~8.3 billion people. For 1 person to have 1/450 of ALL OF IT is neither sustainable nor ethical.

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Kip Ludwig @wildpiguk.bsky.social · 04/06/2026

The good news is knowing IS half the battle. The bad news is the other half usually involves killing people. #GIJoe kind of glossed over that part growing up.

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TK (Takashi DY) Kozai @bioniclab.bsky.social · 03/06/2026

They published it at 412 pages on a Friday afternoon, the slot networks call "take out the trash." OMB-2026-0034 lets political appointees override peer review, ban publication funding, and terminate grants without cause. They gave you 45 days. They're counting on you not reading it.

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Matteo Carandini @carandinilab.net · 01/06/2026

Neuropixels + Optogenetics = Neuropixels Opto Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors. Today in @natmethods.nature.com doi.org/10.1038/s415... Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.

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TK (Takashi DY) Kozai @bioniclab.bsky.social · 01/06/2026

OMB just published 412 pages in the Federal Register (Docket OMB-2026-0034) giving political appointees authority to terminate any NIH grant, override peer review scores, and block you from publishing with federal funds. Comment period closes ~July 13. Thread 🧵

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Kip Ludwig @wildpiguk.bsky.social · 21/05/2026

Note most BCIs are dependent for broad functionality on task inspecific static motor tuning. The evidence suggests tuning curves change based on a number of state variables, meaning portability across tasks without recalibration is an issue.

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Kip Ludwig @wildpiguk.bsky.social · 21/05/2026

I’ve always been struck by the Helms-Tillery studies, where he showed the motor timing curve for isolated single neurons could be changed entirely and back again mirroring quickly changing aspects of task context.

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Kip Ludwig @wildpiguk.bsky.social · 21/05/2026

Not baffling at all. Neuroscientists have shown this over and over. It’s the engineers who aren’t up on neuroscience that get surprised by it. And the majority of the BCI companies are predominantly engineers with very little if any neuroscience training (as an engineer from industry myself).

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TK (Takashi DY) Kozai @bioniclab.bsky.social · 20/05/2026

⚠️ Late Friday afternoon, May 15, while reporters were leaving for the weekend, HHS quietly cut more NIH staff and began moving senior career employees into "at-will" status under the renamed Schedule F. No press release. No published list. A "first tranche," with more to come. 🧵

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Jenna Norton @jenna-m-norton.bsky.social · 15/05/2026

This is the slow death of NIH by design. The architect is Russell Vought. He is the man who architected the RIFs & probationary terminations. He devised the multiyear funding and censorship schemes. If you don't like what you see, let's get him impeached: actionnetwork.org/forms/civil-...

actionnetwork.org

Civil Servants Demand: Impeach Russell Vought

The Office of Management and Budget Director Russell Vought is the central architect driving the destruction of your government. Russell Vought created lawlessness in every part of the Trump administ...

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Kip Ludwig @wildpiguk.bsky.social · 07/05/2026

Do you think the annotation of induced seizures is 1 to 1 or underreported in formal public information?

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Kip Ludwig @wildpiguk.bsky.social · 07/05/2026

My understanding from those who study the history since Dobelle is that every subject who has received a visual cortex implant to treat blindness has had seizures introduced by the stimulation at some point.

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TK (Takashi DY) Kozai @bioniclab.bsky.social · 07/05/2026

🧠 Half of animals receiving the most commonly used clinical brain stimulation frequency developed seizure-like activity. But only after six weeks. Long past the point where most safety studies stop looking. New paper, final version out in Biomaterials. 🧵

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