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Werner Ouwendijk

@wernerouwendijk.bsky.social
57 followers 59 following 8 posts

Assistant Professor @ dept. ViroScience, Erasmus MC Herpesviruses and neurodegenerative diseases

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Reposted by Werner Ouwendijk
Nature @nature.com · 29/08/2026
The scientific community is grappling with concerns about the reliability of these workhorse antibodies go.nature.com/4cbhtka
go.nature.com
More than 18,000 questionable images found in antibody catalogues of 15 companies
Nature - Science sleuth’s findings raise questions for researchers working to improve the reliability of commercial antibodies.
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Reposted by Werner Ouwendijk
Nature Medicine @natmed.nature.com · 26/08/2026
A natural experiment comparing recipients of the live‑attenuated versus recombinant #HerpesZoster #vaccines found that the recombinant vaccine was associated with a lower incidence of #cardiovascular events across seven years of follow‑up
dlvr.it
Recombinant shingles vaccination and the risk of cardiovascular events - Nature Medicine
A natural experiment comparing recipients of the live attenuated versus recombinant herpes zoster vaccines found that the recombinant vaccine was associated with a lower incidence of cardiovascular events across 7 years of follow-up.
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Reposted by Werner Ouwendijk
Nature Reviews Microbiology @natrevmicro.nature.com · 03/03/2026
ICYMI: New online! Varicella zoster virus and the central nervous system
dlvr.it
Varicella zoster virus and the central nervous system
Nature Reviews Microbiology, Published online: 24 February 2026; doi:10.1038/s41579-026-01289-9Varicella zoster virus (VZV) infection causes varicella and herpes zoster and, rarely, severe central nervous system (CNS) complications, including encephalitis. Ogunjimi et al. review the evidence linking herpes zoster with stroke and dementia, summarize innate and adaptive immune responses to VZV-related CNS disease, and debate the consequences of vaccination.
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Werner Ouwendijk @wernerouwendijk.bsky.social · 20/03/2026
Join our Virology course in November 2026!
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Reposted by Werner Ouwendijk
Oliver Harschnitz @harschnitz.bsky.social · 16/03/2026
Just two weeks left to apply to the IGNITION PhD Programme! We’re offering fully funded PhD positions. Join our team @humantechnopole.bsky.social to use cutting-edge human stem cell models to study immune mediated neurodegeneration. For more info check out: ignition-consortium.eu Please share 🙏
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Reposted by Werner Ouwendijk
Nature @nature.com · 07/03/2026
Fluorescent proteins with a quantum upgrade could offer unprecedented views inside cells - the next big thing in biology? go.nature.com/4llx0B5
go.nature.com
Why ‘quantum proteins’ could be the next big thing in biology
Nature - Fluorescent proteins with a quantum upgrade could offer unprecedented views inside cells.
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Reposted by Werner Ouwendijk
Werner Ouwendijk @wernerouwendijk.bsky.social · 19/02/2026
We are looking for a postdoc to join our team! Interested in herpesvirus latency? Apply here: www.werkenbijerasmusmc.nl/en/vacancy/1...
werkenbijerasmusmc.nl
Vacature: Postdoc Researcher in Molecular Virology of Herpesviruses
Herpesviruses are an important cause of severe diseases. Once infected, the virus establishes a lifelong latent infection, which allows it to reactivate later in life. Our team aims to elucidate the v...
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Werner Ouwendijk @wernerouwendijk.bsky.social · 19/02/2026
We are looking for a postdoc to join our team! Interested in herpesvirus latency? Apply here: www.werkenbijerasmusmc.nl/en/vacancy/1...
werkenbijerasmusmc.nl
Vacature: Postdoc Researcher in Molecular Virology of Herpesviruses
Herpesviruses are an important cause of severe diseases. Once infected, the virus establishes a lifelong latent infection, which allows it to reactivate later in life. Our team aims to elucidate the v...
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Reposted by Werner Ouwendijk
Waggoner Lab @labwaggoner.bsky.social · 14/02/2026
@biorxivpreprint.bsky.social EBV reprograms autoreactive anti-CNS B cells as antigen presenting cells in multiple sclerosis www.biorxiv.org/content/10.6... @stanforduniversity.bsky.social @shady-myounis.bsky.social
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Reposted by Werner Ouwendijk
Waggoner Lab @labwaggoner.bsky.social · 09/02/2026
Two doses of Recombinant zoster vaccine reduces dementia risk 51% lower risk of dementia (in females > males) even accounting for healthy vacinee bias versus Tdap @natcomms.nature.com www.nature.com/articles/s41...
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Reposted by Werner Ouwendijk
Nature Communications @natcomms.nature.com · 16/01/2026
#Virology Herpesviruses exploit a cellular membrane protein, once thought to transport chloride, to escape the nucleus by tapping into an ancient membrane fusion process
dlvr.it
ER protein CLCC1 promotes nuclear envelope fusion in herpesviral and host processes - Nature Communications
Herpesvirales utilize a unique nuclear egress route for capsid export. Here the authors show that herpesviruses exploit a cellular membrane protein, once thought to transport chloride, to facilitate membrane fusion and egress from the nucleus.
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Reposted by Werner Ouwendijk
eLife @elife.bsky.social · 02/01/2026
This ‘landmark’ study is now a Version of Record! It shows the #herpes simplex virus-1 uses innovative microscopy and x-ray tomography techniques to examine the roles of 9 proteins in viral formation. buff.ly/Qn8OXAC
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Reposted by Werner Ouwendijk
eLife @elife.bsky.social · 28/10/2025
Evidence from 14 research funding programmes confirms that early winners tend to keep winning (Matthew effect). But the idea that an early setback makes you stronger later doesn’t replicate widely. buff.ly/UEtcRd4
eLife Assessment

This important study reports the results of efforts to replicate two phenomena of significant interest to early-career scientists and scientific policymakers: the Matthew effect and the early-career setback effect. Several previous studies of these effects have focused on early-career researchers with grant proposals that fell just below or just above a funding threshold. Those just above the threshold were more likely to be successful when they applied for funding later in the career (an example of the well-known Matthew effect), while those just below were more likely to go on to have stronger publication records (the early-career setback effect). In this study the Matthew effect was found to be robust across funders, and to generalize from those close to the funding threshold to the whole population. The early-career setback effect was not robust across funders and did not generalize to the whole population. The evidence reported is convincing.
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Reposted by Werner Ouwendijk
virologyunmasked.bsky.social @virologyunmasked.bsky.social · 04/10/2025
Check out are latest post discussing "Are Children Receiving too Many Vaccines?" virologyunmasked.com/2025/09/29/a...
virologyunmasked.com
Are Children Receiving Too many Vaccines?
Molly Cavanaugh, September 2025 From the time of my birth in 2000 to when I turned 18, I received 55 different shots to prevent 16 different diseases.  Diptheria, tetanus, whooping cough, Haem…
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Werner Ouwendijk @wernerouwendijk.bsky.social · 26/08/2025
www.nature.com/articles/s41... Great resource for the VZV community!
nature.com
Multi-proteomic profiling of the varicella-zoster virus–host interface reveals host susceptibilities to severe infection - Nature Microbiology
Proteomic characterization of varicella-zoster virus–host protein interactions and infection-induced changes in a neuronal cell line identifies potential targets for drug discovery and molecular insig...
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Reposted by Werner Ouwendijk
de Volkskrant @volkskrant.nl · 28/06/2025
Het best werkende middel tegen alzheimer? Een vaccin dat gewoon verkrijgbaar is
volkskrant.nl
Het best werkende middel tegen alzheimer? Een vaccin dat gewoon verkrijgbaar is
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Reposted by Werner Ouwendijk
eLife @elife.bsky.social · 10/05/2025
#Herpes viruses are among the most widespread human viruses. Scientists have shown how HSV-1, known for oral and genital sores, assembles in cells thanks to advanced imaging techniques.
buff.ly
Viruses: How herpes is assembled
A combination of imaging techniques reveals how herpes simplex virus type 1 assembles within infected cells, highlighting the roles of essential viral proteins in viral assembly and exit.
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Werner Ouwendijk @wernerouwendijk.bsky.social · 03/04/2025
This is a very exciting study, which suggests that shingles vaccination protects against developing dementia. What could be the underlying mechanisms? Something that we should investigate! www.nature.com/articles/s41...
nature.com
A natural experiment on the effect of herpes zoster vaccination on dementia - Nature
Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...
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Reposted by Werner Ouwendijk
WHO @who.int · 29/03/2025
At least 95% measles vaccine coverage is needed in all communities to prevent #measles and stop outbreaks. The only way to prevent measles? Two doses of measles vaccine. Let’s close the gap and keep measles away!
At least 95% vaccine coverage of 2 doses is needed to stop measles outbreaks.
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Werner Ouwendijk @wernerouwendijk.bsky.social · 22/03/2025
Anaïs from my team presenting our work on VZV yesterday at the Dutch Annual Virology Symposium #DAVS.
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Reposted by Werner Ouwendijk
WHO @who.int · 18/03/2025
The #measles vaccine has saved an estimated 5 lives every second since 2000. 👉Prevent measles by getting vaccinated with two doses of the measles vaccine.
Measles is preventable with just two doses of measles vaccine.
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Reposted by Werner Ouwendijk
Dan Depledge @dandepledge.bsky.social · 14/03/2025
Our latest preprint is online! In which we take a left turn and dive head first into the biology of the RNA polymerase III transcriptome and epitranscriptome Do you want to know more? A small thread follows👇 www.biorxiv.org/content/10.1...
biorxiv.org
Defining expansions and perturbations to the RNA polymerase III transcriptome and epitranscriptome by modified direct RNA nanopore sequencing
RNA polymerase III (Pol III) transcribes cytosolic transfer RNAs (tRNAs) and other non-coding RNAs (ncRNAs) essential to cellular function. However, many aspects of Pol III transcription and processin...
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Reposted by Werner Ouwendijk
Viejo-Borbolla Lab @viejoborbolla.bsky.social · 20/02/2025
Happy to share our publication in #PlosPathogens investigating repression of varicella zoster virus in neuron-like cells: journals.plos.org/plospathogen... Thanks to @dandepledge.bsky.social and other colleagues for their contribution!
journals.plos.org
Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition
Author summary Varicella zoster virus (VZV) establishes latent infection exclusively in human neurons. This phase of infection is characterized by restricted viral gene expression, lack of detectable ...
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Reposted by Werner Ouwendijk
NRC @nrc.nl · 15/02/2025
Anthony Fauci, vijf jaar geleden het gezicht van de Amerikaanse covidbestrijding, wordt nog altijd met de dood bedreigd door complotdenkers. „Ik redde miljoenen levens en word toch als vijand gezien.” buff.ly/40Y2Utx
buff.ly
Arts Anthony Fauci: ‘Ik redde miljoenen levens en word toch als vijand gezien’
Anthony Fauci | Arts en immunoloog: Anthony Fauci, vijf jaar geleden het gezicht van de Amerikaanse covidbestrijding, wordt nog altijd met de dood bedreigd door complotdenkers. „Mensen maken op grond…
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Werner Ouwendijk @wernerouwendijk.bsky.social · 14/02/2025
First grant application of the year submitted; time for weekend!
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Werner Ouwendijk @wernerouwendijk.bsky.social · 15/01/2025
Time for a fresh start in 2025, so let’s build a new network on this social medium platform - where “social” may actually mean something
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