More about the therapeutic strategy!

Brunner et al. report that malate-aspartate shuttle engagement is cell-state dependent and can be modulated by the availability of the amino acid aspartate. In differentiated cells, malate-aspartate s...

Nature Reviews Immunology - A preprint by Heieis et al. shows that O-GlcNAcylation regulates the alternative activation of macrophages and their tissue residency through effects on cell cycle and...

Metabolic dysregulation is a hallmark of aging, but how metabolic pathway activity (flux) changes with age has yet to be broadly assessed. Here, Jankowski et al. measure metabolite concentrations and ...

A preprint by McCaffrey and Delmastro et al. delineates distinct immunometabolic zones of tuberculosis granulomas and reports that hypoxia is a key driver of immune subversion.

Mehr über ihre Forschungsarbeit!

Strengthening Europe’s research and innovation capacity also means investing in its researcher’s long-term careers. This is precisely the goal of the #MSCA…