Reposted by AyalaLab
In some #neurodegenerative diseases, TDP-43 is both lost from the nucleus & forms clumps in the cytoplasm. These two pathologies can be challenging to model but a study in @plosbiology.org presents a new system that captures both features 🧪 Paper: plos.io/4sxw0g9 Primer: plos.io/4bvWGrw