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The British Society of Cell Biology promotes and supports #cellbiology research across the UK and Ireland

Many people with breast cancer can safely avoid chemotherapy with the use of a gene test, potentially sparing them unnecessary side effects without increasing the risk of the cancer returning, accordi...

Why the link between immune infiltration and tumor control varies so strongly across tissues remains unresolved. We propose the “immunometabolic gatekeeping” framework, whereby tissue-intrinsic metabo...

The PIWI-interacting RNA (piRNA) biosynthesis pathway is best studied for its role in suppressing Drosophila germline transposable elements. Piwi, the…

Macrophages don’t just follow chemoattractants to locate sites of infection, they can also create and sculpt them as guidance cues but the mechanisms remain unclear. This study shows that macrophages ...

Fercoq, Cairns, et al. show that mammary tumors induce β2-integrin-dependent neutrophil slowing in lung capillaries, reducing local perfusion in the pre-metastatic niche. Restoring integrin activity n...

Key Points. Nutrient sensing drug-repurposing screen identifies itraconazole, an FDA-approved azole antifungal, as a mitochondrial metabolism inhibitorItra

Key Points. Nutrient sensing drug-repurposing screen identifies itraconazole, an FDA-approved azole antifungal, as a mitochondrial metabolism inhibitorItra

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CCLG: The Children & Young People’s Cancer Association is proud to announce a £600,000 collaboration with Blood Cancer UK that is funding vital new childhood leukaemia research.