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Tyler J Wenzel

@tylerjwenzel.com
1.2K followers 463 following 40 posts

Professor, licensed teacher and health equity advocate. My research studies glia; informs medical policies and guidelines; and develops cell therapies to treat pediatric and adult brain diseases.

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Reposted by Tyler J Wenzel
Emily R. Trunnell, Ph.D. @ertrunnell.bsky.social · 08/06/2026
@tylerjwenzel.com's work at @usask.ca CoM focuses on pediatric neurological conditions. His lab generates human brain organoids from stem cells, allowing interventions to be tested in the exact human cell types affected in children. news.usask.ca/articles/res... #neuroskyence #neurosky #pedsky
“How can we study human disease, if we’re not using human tissue?” he said. “With these stem cells, we basically have an unlimited supply of human tissue, which means we can have a system where we can focus on the human aspects of disease and treatment.”
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Emily R. Trunnell, Ph.D. @ertrunnell.bsky.social · 08/06/2026
🏆2️⃣ @usask.ca scientists recognized for human #organoid research. @tylerjwenzel.com won a @stemcellnetwork.ca Rising Star Award for his pediatric disease research using brain organoids. Dr. Neeraj Dhar received NFRF funding to develop immune organoids for infectious disease. #USask #USaskResearch
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Tyler J Wenzel @tylerjwenzel.com · 16/01/2026
“My motivation is simple,” says Dr. Wenzel. “I want to make kids healthier. I want families to have more certainty and less stress.” Dr. Wenzel's research is examining pediatric brain disease care pathways, [and is] recognized as the top project in the Biomedical category. More: bit.ly/3LgX5nu
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Tyler J Wenzel @tylerjwenzel.com · 15/07/2025
Humbled for our stem cell team at @usask.ca to be ranked as the top biomedical research program in Saskatchewan 2 years in a row. Big thanks to our patient partners and the folks at Jim Pattison Children's Hospital. Looking forward to improving the health of youths! @usaskcomfacdev.bsky.social
Advertisement from the Saskatchewan Health Research Foundation describing that Dr. Tyler J. Wenzel was awarded $150,000 for a research project aiming to develop a new technique to cure brain diseases with limited or no safe treatment options.
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Kelsey Nemec @kel-nem.bsky.social · 30/04/2025
Amped to share this masterclass of a paper spearheaded by @waisenberg.bsky.social, out today in Immunity. Will et al. provide a deeply detailed look into microglia dysfunction in Krabbe disease & show that microglia replacement therapeutically improves disease outcomes! www.cell.com/immunity/ful...
cell.com
Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease
Hematopoietic stem cell transplant is the gold standard for treatment of globoid cell leukodystrophy, also called Krabbe disease. Aisenberg et al. define the molecular signature of disease-associated ...
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Elizabeth Rideout @ejrideout.bsky.social · 30/04/2025
Really looking forward to this today! Grateful to Erin Mulvihill and @roblab.bsky.social for the opportunity to share a little about how biological sex affects islets!
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prinetti.bsky.social @prinetti.bsky.social · 24/04/2025
Remyelination getting way more complex- and interesting…
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Frank Beier @beierlab.bsky.social · 14/03/2025
Changes to MSc, PhD and postdoc funding programs from 🇨🇦 tri councils. Harmonization across councils, more awards, and new eligibility for international PhD and postdoc applicants!
nserc-crsng.gc.ca
NSERC - Latest News - Launch of the new Harmonized Tri-agency Scholarship and Fellowship programs
As announced in Budget 2024, the scholarship and fellowship programs administered by the three federal research funding agencies – the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council (NSERC), and the Social Sciences and Humanities Research Council (SSHRC) – have been streamlined into a new harmonized talent program called the Canada Research Training Awards Suite (CRTAS) that will open for applications in summer 2025.
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John Trant @trantteam.bsky.social · 13/03/2025
And some buddies who do amazing work at Cape Breton don't crack the list. If American, look at where you might want to live. Cost of living in Vancouver and Toronto is nuts. Lower outside of them, and lowest in the prairies (USask and Regina!). Each province and city is a different place.
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John Trant @trantteam.bsky.social · 13/03/2025
Share with US students who had their offers of admission withdrawn for PhD programs: Apply to Canada. Check out Canadian professors, and contact us. Our system works differently here, and we are all still, technically, able to accept students for Fall 2025.
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Stand Up for Science! @standupforscience.net · 01/03/2025
Today is Rare Disease Day, and a great reminder of the importance of NIH and science funding in driving hope 🧬⬇️ www.rarediseaseday.org
rarediseaseday.org
Rare Disease Day 2025 – Raising awareness for people living with rare diseases and their families worldwide.
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Sara Nunes Vasconcelos, PhD she/her/hers🇨🇦🇧🇷 @saravasconcelos.bsky.social · 30/01/2025
Zimmerman’s trailblazing work in #stemcell #cardiomyocyte transplantation in Homo sapiens failing hearts and rhesus macaques 😀👏🏻 Looking forward to reading this in detail #HF #cardiac #regeneration
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Tyler J Wenzel @tylerjwenzel.com · 09/01/2025
Provocative start to 2025. Journal Club 💭: 1) How do we reconcile that other microglia-deficient (eg, CSFR1-/-) models draw different conclusions? Could the remaining immune cells be compensating? 2) Why do these brains have synchronous neuron firing, but brain organoids lacking microglia do not?
nature.com
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus - Nature Neuroscience
Microglia are proposed to have a role in brain development through synaptic engulfment and paracrine signaling. O’Keeffe et al. show that certain neurodevelopmental processes attributed to microglia c...
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Shane Liddelow @liddelowsa.bsky.social · 11/12/2024
3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience. A MUST READ if you're doing transcriptomics. 3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year! (mini thread)
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Tyler J Wenzel @tylerjwenzel.com · 04/12/2024
@samanthamrae.bsky.social @stemcellnetwork.bsky.social Welcome to the Sky! Glad to see you arrive :)
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prinetti.bsky.social @prinetti.bsky.social · 28/11/2024
And of course don’t forget our amazing biennial meetings… the next one? NYC August 2025, with the American Society for Neurochemistry!
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Oscar Woolnough @owoolnough.bsky.social · 27/11/2024
As I've been seeing a lot of job postings here, I've set up a NeuroJobs feed. Add #NeuroJobs to your post if you're recruiting or looking for a PhD, Postdoc, or faculty position in Neuro or an adjacent field. bsky.app/profile/did:...
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Tyler J Wenzel @tylerjwenzel.com · 24/11/2024
@blairkgage.bsky.social Welcome to the blue side Blair!
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Tyler J Wenzel @tylerjwenzel.com · 21/11/2024
@isn-society.bsky.social 😱You have finally arrived! Welcome!
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Tyler J Wenzel @tylerjwenzel.com · 18/11/2024
What is the #1 quality that you look for in a student OR investigator? I got asked this by a potential graduate student. I thought about it and answered “kindness”. Saying no is OK. Making mistakes are OK. Asking for help is OK. There is no need for being mean; it only hinders science advancement.
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Tyler J Wenzel @tylerjwenzel.com · 16/11/2024
How much do I appreciate @jneurochem.bsky.social? I present to you my office mug. Thanks for giving back to the community. PhD candidate or postdoc? Look at their Fundamental Review program (and their schools at neurochemistry.org) to see how you could make lifelong friends & travel awards!
Mug with the abstract from Dr. Wenzels paper in Journal of Neurochemistry printed on it.
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Tyler J Wenzel @tylerjwenzel.com · 21/10/2024
There is not a day that goes by where I am not thankful of the life science gives me. A break from the laboratory to learn about the science behind mental health disorders in Naxos, Greece. Thanks to ISN and their Flagship School. :D
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Tyler J Wenzel @tylerjwenzel.com · 10/05/2024
🚨Our latest #research is live! 👉https://wnzl.ca/wenzel-fncel2024 Any kind shares? ⭐Highlights: 1️⃣1st documentation of #microglia, #oligodendrocytes, #neurons and #astrocytes cells in human #brain #organoids simultaneously 2️⃣Brain organoids process proteins in a manner specific to human brain 🧵(1/9)
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Tyler J Wenzel @tylerjwenzel.com · 13/10/2023
The privilege of being a scientist will never be lost on me - what a cool job. Some photos from giving a keynote speech to the Minister of Advanced Education Hon. Gordon Wyant, University President Dr. Stoicheff, and the rest of the #USask research community about our #regenmed and #organoid work.
Dr. Tyler J. Wenzel talking at a podium about his brain organoid platform that can be used for regenerative medicine and diagnosing adult brain diseases.Dr. Tyler J. Wenzel talking to other professors at the University of Saskatchewan about his presentation.Dr. Tyler J. Wenzel talking to Saskatchewan's Minister of Advanced Education (Honorable Gordan Wyant) about his research's impact on health care.
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Tyler J Wenzel @tylerjwenzel.com · 01/10/2023
#HiSciSky I am a Postdoc at the University of Saskatchewan (in a 🇨🇦 city holding the world-record for largest snowball fight). In the lab, I work with stem cells to improve diagnosis and treatment of neuropsychiatric disorders. Outside, I try to improve health care equity. #Academicsky #neuroskyence
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