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Woojin Han

@thewooj.bsky.social
2K followers 910 following 99 posts

Assoc Prof at Icahn SOM at Mount Sinai NYC 🌆 | Bioengineering & biomaterials for muscle stem cell mechanobiology, disease modeling & therapy discovery🧑🏻‍🔬 www.woojinhanresearch.com

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Reposted by Woojin Han
BWJones @bwjones.bsky.social · 25/09/2026
Science peeps: Looks like SciENcv updated the digital certificate used to sign Biosketch and Current & Pending documents without notification. The old certificate expires Saturday, September 26, 2026. SciENcv docs before that date may fail validation in eRA Commons delaying or blocking submission.
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Woojin Han @thewooj.bsky.social · 16/06/2026
Annual summer color picnic in Central Park as we welcome our summer students to the lab!
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Woojin Han @thewooj.bsky.social · 29/05/2026
Spent Memorial Day on the trails with the lab to recharge, enjoy good company, celebrate recent wins, and kick off the summer. Excited for the science and adventures ahead! @thelaar.bsky.social @thegaaa.bsky.social @thejooosh.bsky.social @thehaan.bsky.social @thesoor.bsky.social
Group photo of our lab during a Memorial Day hike, standing together on a trail overlook and smiling at the camera.
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 21/05/2026
Congratulations to @thesoor.bsky.social (DRS MD/PhD student) from the @thewooj.bsky.social lab, who received the NIH/NIAMS F31 Predoctoral Fellowship! 🌟
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Joel Boerckel @jboerckel.bsky.social · 11/01/2026
Defending PhD student, looking over their thesis: “If I knew then what I know now, I could’ve done all of this in like 9 months.” A thread about my favorite pioneering cave explorers and why I don’t think AI will ever “solve” biology.
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Woojin Han @thewooj.bsky.social · 13/12/2025
Happy holidays from the Han Lab! Celebrating a year of small wins, big milestones, and everything in between. Grateful for this team and looking ahead to the year to come.
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Woojin Han @thewooj.bsky.social · 26/09/2025
I am excited and honored to share my promotion to Associate Professor.
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NY-CURES @nycures.bsky.social · 04/09/2025
🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/
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Larion Santiago @thelaar.bsky.social · 28/08/2025
Excited to share our new publication on mRNA-lipid nanoparticles for muscle regeneration! 💪🏼 Grateful for the guidance and teamwork that brought this project to life. link.springer.com/article/10.1...
link.springer.com
WNT7A mRNA Lipid Nanoparticles Promote Muscle Hypertrophy and Reduce Fatty Infiltration - Cellular and Molecular Bioengineering
Purpose Myosteatosis and muscle atrophy are key pathological features of skeletal muscle degeneration in chronic injuries, degenerative myopathies, and aging. While recombinant WNT7A has shown promise...
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Woojin Han @thewooj.bsky.social · 23/08/2025
Our lab’s work is now published in Cellular and Molecular Bioengineering (CMBE) Journal, appearing in the 2025 Young Innovators Issue. I am excited to share it! link.springer.com/article/10.1...
link.springer.com
WNT7A mRNA Lipid Nanoparticles Promote Muscle Hypertrophy and Reduce Fatty Infiltration - Cellular and Molecular Bioengineering
Purpose Myosteatosis and muscle atrophy are key pathological features of skeletal muscle degeneration in chronic injuries, degenerative myopathies, and aging. While recombinant WNT7A has shown promise...
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Woojin Han @thewooj.bsky.social · 01/08/2025
In the Han Lab, we celebrate every win, big or small, and this season has given us plenty to appreciate. 🧵
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Craig A. Goodman @craigagoodman1.bsky.social · 17/07/2025
Intramuscular adipose tissue restricts functional muscle recovery www.cell.com/cell-reports...
cell.com
Intramuscular adipose tissue restricts functional muscle recovery
Norris et al. demonstrate the detrimental role of intramuscular adipose tissue (IMAT) on muscle regeneration. Following injury, IMAT inhibition enhances muscle regeneration by increasing myofiber dens...
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Reposted by Woojin Han
Abigail Mackey @abigailmackey1.bsky.social · 13/05/2025
Considerations of working with human primary muscle cells - happy to have contributed to this important topic. Thank you Tom Francis and Steve Harridge for inviting me and Casper Soendenbroe to join you! link.springer.com/article/10.1...
link.springer.com
Insights into human muscle biology from human primary skeletal muscle cell culture - Journal of Muscle Research and Cell Motility
This review arises from the symposium held in honour of Prof Jenny Morgan at UCL in 2024 and the authors would like to acknowledge the outstanding contribution that Prof Morgan has made to the field o...
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Justin Gutkowski @justingutbio.bsky.social · 30/04/2025
Excited to announce I just posted a new preLight showcasing the work of @thegaaa.bsky.social in the lab of @thewooj.bsky.social on the effects of 3D confinement on muscle stem cell proliferation and differentiation using an asymmetric hydrogel bilayer model. Check out the post and their paper below:
prelights.biologists.com
3D mechanical confinement directs muscle stem cell fate and function - preLights
Choking under pressure? 3D confinement in hydrogel-based culture inhibits muscle stem cell activation and differentiation
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Woojin Han @thewooj.bsky.social · 17/04/2025
Thrilled to share that our work is featured on the Back Cover of Advanced Biology! This 3D confocal image by GaYoung Park @thegaaa.bsky.social captures muscle stem cells confined between two hydrogel layers with distinct properties. Read more here: advanced.onlinelibrary.wiley.com/doi/10.1002/...
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Woojin Han @thewooj.bsky.social · 12/04/2025
#SFB2025 was an absolute blast and leaving with more energy and inspiration than I came with. Great people, cutting-edge science, and just a fantastic community. Loved meeting new folks and catching up with old friends. Photo 🧵 below 👇 1/n.
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Woojin Han @thewooj.bsky.social · 12/04/2025
Happening Sat 8:30AM! 👇
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Woojin Han @thewooj.bsky.social · 12/04/2025
Happening Sat 8AM! 👇
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Woojin Han @thewooj.bsky.social · 10/04/2025
Happening today! 👇
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Woojin Han @thewooj.bsky.social · 10/04/2025
Happening today! 👇
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Woojin Han @thewooj.bsky.social · 08/04/2025
Han Lab is headed to #SFB2025 in Chicago! Catch us sharing our latest on muscle mechanobiology and bioengineering 🧫💪 @thesoor.bsky.social @thegaaa.bsky.social @thechaar.bsky.social @thelaar.bsky.social @thejooosh.bsky.social
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Soore Oguntuyo @thesoor.bsky.social · 04/04/2025
It was a great experience to hear all the great work condensed into 3 minutes and an honor to win the People's Choice Award at the ISMMS 3-Minute Thesis Competition!
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Hanna Hoang @thehaan.bsky.social · 06/04/2025
I had such an enriching experience at NEBEC these past two days with my lab! Congrats to @thesoor.bsky.social and @thechaar.bsky.social on Best Poster Awards, as well as my PI @thewooj.bsky.social on the Emerging Investigator Award. Really inspiring stuff!
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Woojin Han @thewooj.bsky.social · 06/04/2025
Today’s a special day. Huge congratulations to my MD/PhD student Soore @thesoor.bsky.social and undergraduate student Charlene @thechaar.bsky.social for winning Best Poster Presentation at NEBEC 2025. Proud doesn’t even begin to cover it. Grateful every day to work with such sharp, dedicated team.
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Woojin Han @thewooj.bsky.social · 04/04/2025
#ProudPI 💪
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Journal of Cell Science @jcellsci.bsky.social · 28/03/2025
In their Review, Laura Faure, Valeria Venturini @valeriaventurini.bsky.social and Pere Roca-Cusachs discuss the biological contexts of cell mechanical compression, the associated mechanisms and the experimental systems engineered to compress cells in vitro. journals.biologists.com/jcs/article/...
Cartoon of techniques to apply one-dimensional, in-plane or volumetric cell compression in vitro.
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Woojin Han @thewooj.bsky.social · 24/03/2025
My group plotted a Bluesky ambush this week. They all joined at once—with handles mimicking “thewooj.” 😂💀 Follow the chaos (and our science!): @thejooosh.bsky.social @thesoor.bsky.social @thehaan.bsky.social @thelaar.bsky.social @thechaar.bsky.social @themiiche.bsky.social @thegaaa.bsky.social
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GaYoung Park @thegaaa.bsky.social · 21/03/2025
Proud to share the first paper from Han Lab! advanced.onlinelibrary.wiley.com/doi/epdf/10....
advanced.onlinelibrary.wiley.com
3D Mechanical Confinement Directs Muscle Stem Cell Fate and Function
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Reposted by Woojin Han
Sara Wickstrom @sarawickstrom.bsky.social · 10/03/2025
Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...
nature.com
Measuring and manipulating mechanical forces during development - Nature Cell Biology
This Review discusses the recent advances in experimental approaches to interrogate the mechanical forces that mediate tissue deformations during development, highlighting the insights afforded at bot...
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Woojin Han @thewooj.bsky.social · 05/03/2025
Our latest paper is now published in Adv Biol. In this work, we explored how 3-dimensional confinement regulates muscle stem cell fate and function. Great & fun collab with @mourkiotilab.bsky.social! #myoblue onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
3D Mechanical Confinement Directs Muscle Stem Cell Fate and Function
This study reveals that the physical environment surrounding muscle stem cells (MuSCs) plays a crucial role in their function. Using a 3D hydrogel system, it shows that increased confinement preserve...
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Woojin Han @thewooj.bsky.social · 04/03/2025
Resharing this list for those who joined Bsk more recently! #myoblue
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Matthew Alexander, PhD @mattmuscleguy.bsky.social · 24/02/2025
Excited to share this new collaborative #EmboMolMed work from my lab #ChildrensAL & Jim Dowling labs. Work highlights efforts to generate a new animal model for X-linked myopathy with excessive autophagy (XMEA) and perform corrective drug screening. 1/n tinyurl.com/ym7svnwm
tinyurl.com
X-linked myopathy with excessive autophagy: characterization and therapy testing in a zebrafish model | EMBO Molecular Medicine
imageimageX-linked myopathy with excessive autophagy (XMEA) is a rare disease for which pre-clinical models lack, challenging the ability to understand mechanisms and therapies. The use of the zebrafi...
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Woojin Han @thewooj.bsky.social · 24/02/2025
NYCBEC March ‘25 ed: commiserating & strategizing @ricardo-ca.bsky.social @irenedelazaro.bsky.social @santicorreaphd.bsky.social
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Michael King @profmikeking.bsky.social · 13/02/2025
Late to the party… start me up, my Bleeps!
A beer koozie that says: “Shell We Drink?” With a picture of a shell.
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Dada Pisconti @dadapisconti.bsky.social · 03/02/2025
Good morning #MyoBlue 🧪 In the midst of all this chaos, we want to stay positive and continue to do what we love the most! We are hiring a technician to help with ongoing satellite cell and muscle projects. Please repost large and wide Interested folks can apply here, enquiries to me are welcome
stonybrooku.taleo.net
Research Support Specialist
Click the link provided to see the complete job description.
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Woojin Han @thewooj.bsky.social · 10/02/2025
Here’s my take on milk clarified Empress negroni to celebrate surviving and getting through a long week 🥃
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Woojin Han @thewooj.bsky.social · 08/02/2025
Deleted my Twitter/X account, finally.
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Woojin Han @thewooj.bsky.social · 06/02/2025
This week is a special one. Celebrating my birthday with the best lab/team & students I could ask for & had the honor and privilege hosting prof Heungsoo Shin in NYC at Sinai/Columbia with @ricardo-ca.bsky.social
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Dr. Jeffrey Millman @jeffreymillman.bsky.social · 04/02/2025
Big #RegenerativeMedicine advance! New study demonstrates the use of iPSC-heart muscle to treat a patient with heart failure. The patches successfully engrafted, contributing to heart repair. Patient survived 3 months before receiving a heart transplant www.nature.com/articles/s41...
nature.com
Engineered heart muscle allografts for heart repair in primates and humans - Nature
Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques, leading ...
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The Greising Lab @greisinglab.bsky.social · 07/01/2025
Our lab is looking to add a postdoc to our team investigating skeletal muscle function after injury, applicants with expertise in physiology and imaging very welcome! hr.myu.umn.edu/jobs/ext/364... Reach out with any questions
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Prof. Brian Aguado @brianaguado.bsky.social · 20/12/2024
Submit your research to a special issue in Biomedical Materials Research Part A (JBMR-A) called "Biomaterials for Women's Health" - super excited to guest edit with Jessica Weaver and working with Kent Leach to put together an exciting issue! 🧪 Learn more and submit your article: lnkd.in/gZRm8Zhs
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Matthew Alexander, PhD @mattmuscleguy.bsky.social · 20/12/2024
New #NPJRegenMed paper: Myoblast-derived ADAMTS-like 2 promotes skeletal muscle regeneration after injury. #MyoBlue tinyurl.com/ywrhzv79
tinyurl.com
Myoblast-derived ADAMTS-like 2 promotes skeletal muscle regeneration after injury - npj Regenerative Medicine
npj Regenerative Medicine - Myoblast-derived ADAMTS-like 2 promotes skeletal muscle regeneration after injury
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Woojin Han @thewooj.bsky.social · 18/12/2024
Happy holidays from Mount Sinai ORL! 🎅🌲
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Woojin Han @thewooj.bsky.social · 13/12/2024
Happy holidays! ❄️ The 2nd annual Han Lab cook-off was a huge success and fun. Everyone brought their A-game! Yes, we now have a plaque with the winner’s names engraved…
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Woojin Han @thewooj.bsky.social · 10/12/2024
❄️ NYCBEC December edition ❄️
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Woojin Han @thewooj.bsky.social · 25/11/2024
I noticed there wasn’t a starter pack for skeletal muscle scientists, so I made one as the muscle community continues to migrate here. Drop a comment if you’d like to be included! go.bsky.app/3hKK1WX
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Woojin Han @thewooj.bsky.social · 21/11/2024
The Icahn School of Medicine at Mount Sinai and Rensselaer Polytechnic Institute (RPI) launched the joint Center for Engineering and Precision Medicine (CEPM). Applications are now open for our inaugural PhD in Health Science Engineering. Apply by January 1, 2025! cepmresearch.org/academic-pro...
cepmresearch.org
Academic Programs - Center for Engineering and Precision Medicine
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Garrett Beeghly, PhD @gbeeghly.bsky.social · 18/11/2024
I didn’t see a general starter pack for people in the #BME and #BioE communities so I started to put one together. Let me know if I’ve missed anyone in particular or if you’d like to be added! #ScienceSky #AcademicSky go.bsky.app/9nMCGLK
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Abigail Mackey @abigailmackey1.bsky.social · 18/11/2024
🤩How does exercise keep us strong? Led by Casper Soendenbroe, motor neurons are better supported by muscle stem cells and fibroblasts from life long exercisers v inactive ppl🏃 #keepmoving 🙏 @benchazaud.bsky.social #TeamLyon 🙏 @lundbeckfonden @ismcopenhagen.bsky.social doi.org/10.1111/acel...
doi.org
Muscle fibroblasts and stem cells stimulate motor neurons in an age and exercise‐dependent manner
Muscle biopsies were taken from males and females differing in age and exercise habits. Mononucleated cells were isolated and purified into muscle stem cells (MuSC) and muscle fibroblasts (FIB). Neur...
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Woojin Han @thewooj.bsky.social · 14/11/2024
Great day at the annual musculoskeletal research symposium at Montefiore/Einstein SOM. Lab photo with the best team. Super excited for our MS student Larion getting a young investigator award!
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