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SCBRM Department @ MSSM

@scbrmmountsinai.bsky.social
26 followers 67 following 84 posts

Follow us for news from the Stem Cell Biology and Regenerative Medicine department at Mount Sinai in NYC! 🧬🔬🧪

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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 05/10/2026
Congratulations to PhD candidate Tori Kroon, from Nilsson Holguin lab, for her new manuscript accepted in Aging Cell titled “β-Catenin-Deficient Intervertebral Disc Cells Reduce Chemotactic Transcription and Myeloid Cell Recruitment to Injured Discs of Mice” 👏
onlinelibrary.wiley.com
<fi>β‐Catenin</fi>‐Deficient Intervertebral Disc Cells Reduce Chemotactic Transcription and Myeloid Cell Recruitment to Injured Discs of Mice
(Left) In young discs, Wnt signaling-replete nucleus pulposus cells secrete ECM components and, upon disc injury, cytokines to recruit myeloid cells. (Right) Whereas, β-catenin-deficient disc cells, ...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 05/10/2026
Congratulations to the Zhe Ying Laboratory! 🌟 Their study uncovers how loss of the critical tumor suppressor p53 enables mutant cells to expand through normal tissue. 🧪 Link to Paper: www.science.org/doi/10.1126/...
science.org
Loss of the tumor suppressor p53 generates a signaling gradient that drives epithelial clonal expansion
Although tumor protein p53 (TP53) mutations are among the most common lesions in epithelial cancers, how p53 loss drives unrestrained clonal expansion remains unclear. Working with mouse epidermis, we...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 05/10/2026
Check out this recent article highlighting the amazing work happening here in the SCBRM Department! ✨ Link Here: www.nature.com/articles/d42...
nature.com
Can stem cells help turn back the clock?
From brain organoids to rejuvenated blood stem cells, researchers are exploring how stem-cell biology could help combat ageing and disease.
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Reposted by SCBRM Department @ MSSM
Joel W. Blanchard, PhD @joelwblanchard.bsky.social · 30/09/2026
I'm excited to share that I've been selected as a 2026 Cardinal Family Scholar by Cure Alzheimer's Fund. This funding will help build on our recent Cell study here @scbrmmountsinai.bsky.social to develop therapies targeting APOE4-driven vascular damage in Alzheimer's. curealz.org/news-and-eve...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 25/09/2026
Congratulations to the @joelwblanchard.bsky.social lab on their two new studies on miBrains 🧠 Read more about their findings here: www.mountsinai.org/about/newsro...
mountsinai.org
Mount Sinai Researchers Identify How APOE4 Gene Damages Brain Blood Vessels in Alzheimer’s Disease
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Reposted by SCBRM Department @ MSSM
Joel W. Blanchard, PhD @joelwblanchard.bsky.social · 24/09/2026
Special shoutout to first author Braxton Schuldt for leading this work as part of his PhD, & congratulations to our entire team here @scbrmmountsinai.bsky.social. Excited to build on these findings and see what else we can uncover with #miBrains. Read the full paper: www.cell.com/cell/abstrac...
cell.com
A pericyte-to-myofibroblast transition links APOE4 to cerebrovascular degeneration
APOE4 causes a pericyte-to-myofibroblast transition that promotes cerebrovascular fibrosis and perivascular amyloid accumulation. TGF-β inhibition reverses this pathological remodeling and thus presen...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 14/09/2026
Congratulations to Miguel Quijada-Alamo, a postdoctoral fellow from the Elvin Wagenblast lab 🌟 He recently presented his work at the International Society of Experimental Hematology (ISEH) Annual Scientific Meeting in Frankfurt Germany and was awarded the Christa Muller-Sieburg Award!
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 01/09/2026
Congratulations to Henry Weith, a 5th year PhD student in DRS, on presenting at the 2026 Gordon Research Conference on Epithelial Stem Cells and Niches! 🌟 He gave a wonderful talk and won the poster award.
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 19/08/2026
A huge congratulations to Anagha Menon from the Ghaffari Lab! 👏 Her F31 titled 'PINK1 in the regulation of terminal erythroid maturation and enucleation' was awarded. Anagha also received the NIDDK-funded NY KUHRS fellowship! nyckuhr.org/trainees/
nyckuhr.org
Trainees - NYCKUHR
Trainee educational resources Trainee educational resources trainees profiles Pre-doctoral Students Anagha Menon Pre-doctoral Student about me I grew up in Bangalore, India and became interested in de...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 14/07/2026
Congratulations to the Ezhkova lab on their new publication in Nature Communications, "Oncogenic Ras drives EED degradation and PRC2 dysfunction to promote aggressive squamous cell carcinoma" Read more here: www.nature.com/articles/s41...
nature.com
Oncogenic Ras drives EED degradation and PRC2 dysfunction to promote aggressive squamous cell carcinoma - Nature Communications
Oncogenic Ras signaling is linked to aggressive squamous cell carcinoma (SSC). Here, authors show that Ras signaling leads to proteasomal degradation of EED, resulting in reduced H3K27me3 and activati...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 25/06/2026
Exciting news for our SCBRM community! We are thrilled to share that the Icahn School of Medicine at Mount Sinai has been ranked #4 in Cell Biology in the U.S. News & World Report Best Global Universities rankings 🌟
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 24/06/2026
Congratulations to the Ezhkova lab on their new publication, "Mouse model of Merkel cell carcinoma derived from the hair follicle" in the Journal of Investigative Dermatology! 🚀
jidonline.org
Mouse model of Merkel cell carcinoma derived from the hair follicle
Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer with a poorly understood cell of origin and initiation process. Most MCC tumors feature monoclonal integration of Merkel c...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 24/06/2026
Congratulations to Dr. Tianliang Sun, recipient of the 2026 AASLD Summer Liver Academy Meeting (SLAM) Junior Faculty Scholar Award! 🌟🌟
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 16/06/2026
A huge congratulations to our very own Dr. Chris Sturgeon on receiving the Aspen Institute Italia Award, which recognizes high impact collaborative work between Italian and American scientists 🏆
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 11/06/2026
Congratulations to Kaustav Mukherjee, PhD for being awarded the 2026 - 2027 Cooley's Anemia Research Fellowship Award! 👏
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 27/05/2026
Congratulations to James J Bieker, PhD, who has been awarded years 32-36 of his long running NIDDK R01 grant “Function of a Putative Determinant in Hematopoiesis” 🚀
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 21/05/2026
Congratulations to @thesoor.bsky.social (DRS MD/PhD student) from the @thewooj.bsky.social lab, who received the NIH/NIAMS F31 Predoctoral Fellowship! 🌟
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 18/05/2026
Come join us for our weekly Works In Progress seminar! Today's presentation is by Hanna Hoang from the Han lab on "Reprogramming Mesenchymal Stromal Cells Using MyoD-Lipid Nanoparticles for Treatment of Rotator Cuff Pathologies" 💪🚀 Annenberg 25-51 @ 12PM
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 07/05/2026
Congratulations to Nicole Dubois for receiving the Excellence in Science Teaching Award from the Institute for Medical Education (IME) at the Icahn School of Medicine at Mount Sinai. 💫
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 07/05/2026
Show your support for Dr. Michael Rendl at WCHR 2026! 🚀 "I am excited about speaking at the upcoming World Congress for Hair Research 2026 in Seoul! Looking forward to sharing insights and connecting with colleagues from around the world." #WCHR2026 #HairResearch #Dermatology #Seoul
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 07/05/2026
We are excited to share a new publication from Ya-Wen Chen's lab that just came out in Nature Communications titled "Unveiling alternate pathways for SARS-CoV-2 infection via extracellular vesicle-mediated transfer of ACE2 and TMPRSS2"! 🌟 Read it here: www.nature.com/articles/s41...
nature.com
Unveiling alternate pathways for SARS-CoV-2 infection via extracellular vesicle-mediated transfer of ACE2 and TMPRSS2 - Nature Communications
Extracellular vesicles from lung epithelial cells deliver ACE2 and TMPRSS2 to recipient cells, enabling SARS-CoV-2 infection beyond receptor-expressing cells and expanding viral tropism.
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 27/04/2026
Congratulations to Henry Weith for being chosen to receive the Graduate Student Excellence in Teaching Award from the Institute for Medical Education (IME) at the Icahn School of Medicine at Mount Sinai. ✏️
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 27/04/2026
Join us today for our Works in Progress seminar! Talks today will be by PhD candidates Anupriya Ramamoorthy (Rangan lab) and Grace Jones (Krauss lab). Seminar will be held in Icahn 13-82 @ 12PM 🚀
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 23/04/2026
Congratulations to Dr. Sarah Millar, chair of SCBRM, for being picked to give a talk at WCHR 2026 in Seoul! 🧬🌟 "I’m excited to be speaking at WCHR 2026 in Seoul! Looking forward to sharing insights and connecting with colleagues from around the world." #WCHR2026 #HairResearch #Dermatology #Seoul
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 23/04/2026
Congratulations to Miranda Wilson for winning of one of the 2026 Graduate School PhD Commencement Achievement Awards! 👏 Miranda received the Award for Outstanding Research in Development, Regeneration, and Stem Cells. 🧬
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 23/04/2026
Join us today in Icahn 13-82 for a seminar talk by Dr. Mira Kassouf from @ox.ac.uk @ 12PM. Dr. Kassouf's talk will be on "Facilitators may represent a new class of regulatory elements" 🌟
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 20/04/2026
Join us today @ 12PM in Icahn 13-82 for a talk by our very own Henry Weith, a PhD Candidate in the May Lab! Henry will be talking about "Distinct tissue resident macrophage behaviors regulating exocrine development” 🦠👨‍🔬
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 17/04/2026
Congratulations to Linh Vuong from the Mlodzik lab! 🌟 Linh's paper got accepted at Science Advances and describes Pasovec (Psv) as a critical component required for nuclear β-catenin/Arm localization in Drosophila and vertebrate cells. You can read it here: www.science.org/doi/full/10....
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 16/04/2026
Please join us for a talk today @ 12PM in Icahn 13-82 by Dr. William Bement from @uwmadison.bsky.social ! 🦡🌟 His talk will be on "The Excitable Cell Cortex"
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 16/04/2026
Exciting news out of the Holguin Lab! 🌟 A huge congratulations to our very own Helen Lin who is a Regeneron STS Top 300 Scholar for her summer project "Human intervertebral disc degeneration, sex, and aging increase alpha-1 antitrypsin expression"! #Regeneron #SocietyForScience
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 09/04/2026
Please join us today for a talk by Dr. Sánchez Alvarado from @stowersinstitute.bsky.social on "Understanding the Sources of Regenerative Capacity In Animals" 🌟🔬🧪
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 09/04/2026
We are proud to share that SCBRM Chair Emeritus Dr. Marek Mlodzik received the prestigious Jacobi Medallion Award from Mount Sinai in recognition of his exceptional contributions to science and his outstanding leadership of the department! 🌟 Congratulations Dr. Mlodzik!
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 08/04/2026
Massive congratulations to Dr. Chris Sturgeon who was awarded an $8.2 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health! 🚀
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 08/04/2026
Congratulations to Grace Jones of the Krauss lab. Grace won the best poster award at the 2026 Mount Sinai Cancer Biology retreat! Grace is a fifth-year PhD student, and her poster was titled, “Roles of Rho family GTPases in muscle stem cell quiescence” 🎉👏
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 30/03/2026
Congrats to the Holguin lab! Their manuscript titled “Raloxifene injections normalize age-related mechanical sensitization in female and male mice and augment intervertebral disc structure in old female mice” was accepted for publication in a top orthopedics journal, Osteoarthritis and Cartilage.
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 30/03/2026
Hey SCBRM-ers! Want to see a great new play about hot-button issues in aging and regeneration research? About a tech billionaire who wants to live forever and has heard of parabiosis with mice? Check out “Spare Parts” by David Glass from Regeneron. At Theatre Row now through April 30!
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 30/03/2026
Chih-wen Chu from Dr. Sergei Sokol's lab and Ratchell Sadovnik from Dr. Nan Yang's lab will be presenting at the SCBRM WIP today, March 30th, 2026, from 12:00pm – 1:00pm in Icahn Building, 13th Floor, Room 13-82. See you there! 🌟
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 30/03/2026
Dr. Eirini Papapetrou, MD, PhD of the Icahn School of Medicine at Mount Sinai has been selected as this year’s recipient of the McCulloch and Till Award! 🌟
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 26/03/2026
Pleas join us today for a talk by Dr. Elizabeth Chen from UT Southwestern Medical Center on "The Asymmetric Fusogenic Synapse: A Conserved Mechanism Underlying Cell-Cell Fusion” @ 12PM in Annenberg 25-51
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 26/03/2026
Congratulations to Paula Restrepo and the Ji lab for their recent publication in Nature Genetics @nature.com
nature.com
Single-cell spatial transcriptomic analysis of human skin anatomy - Nature Genetics
This study presents an organ-wide spatial transcriptomic analysis of human skin from different anatomical sites using a combination of MERFISH technology and existing datasets from healthy and disease...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 23/03/2026
Congratulations to Dr. Nilsson Holguin on being featured in the @trinitycollege.bsky.social Alumni Q&A Winter 2026 Issue. Read the interview here! www.trincoll.edu/reporter/win...
trincoll.edu
Nilsson Holguin ’05
DEGREES: Engineering, with a concentration in biomedical engineering; M.S., Ph.D. in biomedical engineering, Stony Brook University JOB TITLE: Assistant professor, Department of Orthopedics, Icahn Sch...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 19/03/2026
Please join us today in Annenberg 25-51 for a talk by Dr. Xaralabos Varelas from @bumedicine.bsky.social titled "YAP/TAZ-mediated Mechanotransduction in Lung Biology and Disease” 🫁🩺 #SCBRM #lungbio
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 19/03/2026
Congratulations to Dr. Allison Bond for being awarded the @alzassociation.bsky.social Alzheimer’s Association Research Grant for All for her project "The Role of Oligodendrocyte Precursor Cells in Alzheimer's Disease” #ALZFunded 🧠💪🩺
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 18/03/2026
Congratulations to Dr. Margaret Baron, Director Emeritus of ISMMS MSTP, for co-authoring a paper on a toolkit for defining and assessing competencies that are widely considered to be essential for physician-scientist training, with a focus on MD-PhD programs 🩺 @aamc.org #MSTP #MD-PhD #meded
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 12/03/2026
The 2026 @isscr.org Public Service Award has been presented to Stem Cell COREdinates, an international consortium that connects hPSC core facilities worldwide. The consortium was co-founded in 2009 by Sunita D’Souza (Mount Sinai) and Mark Tomishima (MSKCC). tinyurl.com/isscr-COREdi...
tinyurl.com
The ISSCR Honors Stem Cell COREdinates and CorEUstem with the 2026 ISSCR Public Service Award — International Society for Stem Cell Research
Global Networks Recognized for Transforming Collaboration, Advancing Standards, and Expanding Equitable Access in Stem Cell Science The International Society for Stem Cell Research (ISSCR) is pleas...
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 12/03/2026
Please join us for an interesting talk by Dr. Sue Hammoud from @umich.edu titled "From Chromatin to Code: Programming the Sperm Epigenome" @ 12PM in Annenberg 25-51!
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 06/03/2026
The Sokol lab recently published their paper titled "Planar polarization of endogenous ADIP during Xenopus neurulation" where their findings suggest that endogenous ADIP senses mechanical cues via the cytoskeleton to control collective cell behaviors during vertebrate morphogenesis. 👏🐸
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 06/03/2026
We are excited to announce that Rob Krauss was recently named Co-Editor-in-Chief of Skeletal Muscle, a key journal in his field. Congratulations, Rob! 🥳🎉👏💪 #skeletalmuscle #editorinchief #SCBRM
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 02/03/2026
Please join us at the SCBRM WIP today where Adelajda Turku from Dr. Georgia Panagiotakos lab and Maria Mercedes from Dr. Elena Ezhkova’s lab will be presenting @ 12:00pm! 🧬🧠 #DYRK1A #skinresearch #neuroscience #developmentalbiology #SCBRM
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SCBRM Department @ MSSM @scbrmmountsinai.bsky.social · 26/02/2026
Join us today @ 12PM in Annenberg 25-51 for a talk by Dr. Ken Zaret from @pennmedicine.bsky.social titled "Initiating Cell Fate Changes in Health and Disease” 🧬🧪🔬
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