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theNiessingLabs

@theniessinglabs.bsky.social
140 followers 118 following 26 posts

We use structural biology, biochemistry, and (stem) cell biology to understand the roles of RNA-binding proteins in neurodevelopmental #PURA Syndrome and neurodegeneration. We are located at @uniulm.bsky.social and at @helmholtzmunich.bsky.social, Germany.

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Simon Bullock @simonbullock11.bsky.social · 28/09/2026
How are mRNAs linked to molecular motors in mammalian cells? In our new preprint, we show that FXR1/2 are RNA adaptors for the microtubule motor dynein. Our findings have also prompted us to rethink how activating adaptors contribute to motor-based transport (1/n)
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Joachim Frank @joachim123.bsky.social · 09/08/2026
Academic freedom measured across the world -- A Swedish project. Look where we are.
A world map of academic freedom measured across the world -- A Swedish project.  The USA is shown with 0.4 on a scale from 0 to 1.  For comparison, Canada is 0.85, Ireland 0.92.
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theNiessingLabs @theniessinglabs.bsky.social · 27/09/2026
🎓🎉 It’s official: Dr. David Settele! Huge congratulations to David on successfully defending his PhD thesis! We’re incredibly happy to celebrate this milestone with you and wish you all the best for what comes next. Congrats from the entire Niessing Lab! 🥂
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theNiessingLabs @theniessinglabs.bsky.social · 20/09/2026
Hi, I’m Rob! Originally from Poland, I’m a structural biologist studying protein–nucleic acid interactions. My expertise includes protein production, crystallization & X-ray crystallography. #MeetTheTeam #BehindTheScience #TheNiessingLabs
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theNiessingLabs @theniessinglabs.bsky.social · 11/09/2026
Over the last three days, our PhD student Silvia represented the Niessing Labs at the 2026 GSCN Conference in Berlin! 🧬 She shared our research on PURA syndrome, connected with fellow stem cell researchers, and brought home new ideas and inspiration. 🔬 #stemcell #purasyndrome #raredisease #phdlife
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meisterlab.bsky.social @meisterlab.bsky.social · 02/09/2026
Kickoff of the 8th Biennial Meeting of the LARP Society! Welcome to Regensburg! #LARP2026 A fantastic opening keynote by Matthias Hentze set the stage for the meeting, followed by a wonderful evening reception. Looking forward to the exciting science ahead.
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theNiessingLabs @theniessinglabs.bsky.social · 30/08/2026
Hi, I’m Chiara! After joining the Niessing lab in 2023 for my Bachelor’s thesis on the PUR protein family, I returned as a PhD student in 2026. I now study PURA syndrome, combining basic research with a close connection to the PURA community and affected families. #science #labmembers #purasyndrome
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theNiessingLabs @theniessinglabs.bsky.social · 23/08/2026
Hi, I’m Silvia from Italy. I joined the Niessing Lab in 2023 for my Master’s thesis and stayed on as a PhD student. I’m excited to be part of such a great team, exploring how PURA shapes neuronal development and hoping our research can make a difference for PURA kids and their families. #labmembers
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theNiessingLabs @theniessinglabs.bsky.social · 16/08/2026
Hi, I’m Jacob! After my master’s in Biotechnology (2024), I joined the Niessing Lab in Ulm as a PhD student. I’m passionate about understanding PURA syndrome and connecting with affected families. In the lab, I work to advance our knowledge—and enjoy annoying my students and lab mates. #meettheteam
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theNiessingLabs @theniessinglabs.bsky.social · 09/08/2026
Hi, I'm Vera. I've been a technician at the Munich labs for 13 years. I specialized in cell biology and love combining science with patient care. Even behind the scenes, I know that my work helps keep the lab running and support research that ultimately benefits patients. #meettheteam #science
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theNiessingLabs @theniessinglabs.bsky.social · 02/08/2026
What a wonderful evening celebrating 20 years of the Niessing Labs! 🧬🥂 Great to reconnect with former lab members, celebrate current projects, and look back on two decades of exciting science. Here’s to many more discoveries ahead! ✨ #NiessingLabs #20Years #LabLife #Science
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theNiessingLabs @theniessinglabs.bsky.social · 26/07/2026
My name is Simi. For more than 10 years, I have been working at the Munich research group, where I handle all administrative tasks and, have also been responsible for the PURA Biobank at the Helmholtz Munich. I earned my degree in biology from LMU and I am thrilled to be part of this great team 🙂
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Reposted by theNiessingLabs
theNiessingLabs @theniessinglabs.bsky.social · 19/07/2026
Representing the Niessing labs at this year's B2Run as part of the Helmholtz Munich team! A great evening of running, team spirit, and fun outside the lab. Looking forward to the next one! 🏃‍♀️ #B2Run #HelmholtzMunich
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theNiessingLabs @theniessinglabs.bsky.social · 19/07/2026
Representing the Niessing labs at this year's B2Run as part of the Helmholtz Munich team! A great evening of running, team spirit, and fun outside the lab. Looking forward to the next one! 🏃‍♀️ #B2Run #HelmholtzMunich
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theNiessingLabs @theniessinglabs.bsky.social · 12/07/2026
Meet the faces behind the science🔬 Over the next weeks, we’ll introduce each member of our team. Starting off with Manu “Hi ☺️ I am the technician at the Ulm labs. I’ve been in this group for almost 5 years. I did my master degree in Biology and spend some time doing field work in South America“ #lab
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theNiessingLabs @theniessinglabs.bsky.social · 29/06/2026
This past weekend at the PURA Conference in Munich reminded us what makes rare disease research so special: bringing together families, clinicians, and researchers from around the world. We were honored to receive the PURA Hero Award 2026. #Purafoundation #community #purasyndrome #Rare #TeamPURA
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Reposted by theNiessingLabs
Michaela Müller-McNicoll @mixmue.bsky.social · 04/03/2026
We are excited to share our new preprint: iCLIP3 — an improved protocol for transcriptome-wide mapping of protein–RNA interactions at single-nucleotide resolution.
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theNiessingLabs @theniessinglabs.bsky.social · 09/02/2026
Searching for a human neural cell line with greater differentiation potential than SH-SY5Y cells? Check out the human #neural #stem_cell line HNSC.100. Differentiates into astrocytes, neurons & oligodendrocytes. On #BioRxiv, we provide protocols, markers, ABs, karyotyping & RNAseq: shorturl.at/y0aJG
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theNiessingLabs @theniessinglabs.bsky.social · 23/12/2025
Merry Christmas and Happy New Year to all of you! 🎄
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Uni Ulm @uniulm.bsky.social · 06/11/2025
Von Bio-inspirierten Technologien über medizinische & gesellschaftliche Herausforderungen bis hin zur Neurochirurgie spannt sich der Bogen der Vortragsreihe der Ulmer Universitätsgesellschaft. Eintritt frei!🆓 t1p.de/uug_33 *stg #uulm
Veranstaltungsplakat der 33. Vortragsreihe der UUG
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theNiessingLabs @theniessinglabs.bsky.social · 29/10/2025
We are so grateful! PURA Syndrome Deutschland e.V. makes donation to support our research on #PURA syndrome at @helmholtzmunich.bsky.social, #Rare #puraperfect.
Donation of 10.000 Euro to our lab
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theNiessingLabs @theniessinglabs.bsky.social · 13/10/2025
Had an exciting visit to the German University in Cairo (www.guc.edu.eg). I was impressed by how much this university contributes to mutual understanding between Europe and the Middle East through academic exchange. Much needed these days! Close collaboration with #UUlm and supported by #DAAD.
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theNiessingLabs @theniessinglabs.bsky.social · 28/06/2025
Today we launched the #PURA Biobank at @www.helmholtz-munich.de for patients with #purasyndrome. Biosamples will support research and development of treatment strategies. Big thanks to PURA Syndrome Foundation USA for your constant support! #Rare #puraperfect www.helmholtz-munich.de/en/pura-biob...
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theNiessingLabs @theniessinglabs.bsky.social · 28/06/2025
Great collaboration of Simone Heber and Anne Ephrussi with our lab on Staufen-dependent RNA localization!
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Reposted by theNiessingLabs
Evelina Tutucci @anilevetu.bsky.social · 12/04/2025
www.biorxiv.org/content/10.1...
biorxiv.org
Perturbing RNA localization for functional study in neurons
Spatial RNA organization plays a pivotal role in diverse cellular processes and diseases, but the functional implications of spatial RNA localization remain underexplored. We present CRISPR-mediated t...
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theNiessingLabs @theniessinglabs.bsky.social · 10/04/2025
We participated in Interact Munich 2025, where we had the opportunity to present our research through posters, connect with fellow young researchers, and attend inspiring talks. A big thank you to the organizing team for making such a fantastic event possible! #interact2025
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theNiessingLabs @theniessinglabs.bsky.social · 31/03/2025
Lab work is important but also consumes lots of energy and resources. We are the first lab at @www.helmholtz-munich.de to be awarded with the Gold level LEAF (Laboratory Efficiency Assessment Framework) certificate of the @ucl.ac.uk for our efforts to become a more sustainable laboratory!
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theNiessingLabs @theniessinglabs.bsky.social · 27/02/2025
Terrified by the global developments and current politics? We took a break from the world by attending a hip-hop dance class. Lots of excitement, confusion, and happiness. We can highly recommend it as a mental therapy...
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Agnel Sfeir @agnelsfeir.bsky.social · 15/02/2025
I Used to Run the N.I.H. Here’s What Worries Me. www.nytimes.com/2025/02/14/o...
nytimes.com
Opinion | American Science is Under Attack (Gift Article)
The Trump administration hobbles research and endangers the public health.
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<interact> Munich 2025 @interactmunich.bsky.social · 14/02/2025
🚨 Early Bird Registration Closing Soon for Interact Munich 2025! 🚨 ⏳ Don’t miss out! Our Early Bird pricing for Interact Munich 2025 ends on February 17th – secure your spot today and save on registration!
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König Lab @koenig-lab.bsky.social · 15/01/2025
Check out our recent work on CDS #m6A mediated RNA decay (CMD)! Decay relies on ribosome pausing at m6A containing codons. Great collab with the Zarnack lab & colleagues. Thank you @uniwuerzburg.bsky.social , @imbmainz.bsky.social and RMap🥳 www.cell.com/molecular-ce...
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theNiessingLabs @theniessinglabs.bsky.social · 09/01/2025
Now out on bioRxiv: our collaboration with Simone Heber, Anne Ephrussi and Jeff Chao reveals how Staufen interacts with the kinesin adapter aTm1 to localize oskar mRNA in #Drosophila oocytes, modulating kinesin-1 dependent mRNA transport. #RNAsky #RNA doi.org/10.1101/2024...
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RCSB Protein Data Bank @rcsbpdb.bsky.social · 06/01/2025
After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month. We are very grateful for his service. @jiwasa.bsky.social will continue the series, beginning with January's article on Assembly Line Polyketide Synthases Details: cdn.rcsb.org/rcsb-pd...
cdn.rcsb.org
EDUCATION CORNER: Molecule of the Month: Celebrating  25 Years of Storytelling and Announcing New Beginnings
After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month series.  Janet Iwasa will be continuing the series for PDB-101.
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<interact> Munich 2025 @interactmunich.bsky.social · 05/12/2024
🌟 Welcome to <interact> 2025 🌟 We’re thrilled to announce the most exciting student-organised scientific conference is back in 2025! 🎉 📅 Mark your calendars: 🗓️ April 3-4, 2025 📍 Venue: Biomedical Center (BMC), LMU Munich
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theNiessingLabs @theniessinglabs.bsky.social · 12/12/2024
Hello Bluesky 🤠 Our very first post is about our recent paper in Nucleic Acids Research: so-called PUN motifs are repetitive elements enabling proteins to catalyze #RNA folding and RNA-dependent #condensate formation ( #LLPS). 15% of human proteins contain 3 or more PUN motifs. See bit.ly/4fZ3f54.
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