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Tomás Di Domenico

@tdido.eu
50 followers 111 following 9 posts

Director of IT and Scientific Computing at @cniostopcancer.bsky.social

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Reposted by Tomás Di Domenico
CNIO Bioinformatics Unit @bioinformatics.cnio.es · 22/07/2026
🚨 Últimas plazas disponibles para cursar el Máster en Bioinformática @saludisciii.bsky.social @cniostopcancer.bsky.social @bsc-cns.bsky.social Si quieres ser bioinformático/a este es el momento. Empezamos el curso el 28 de Septiembre! 👉 Más información e inscripción: masterbioinformatica.com
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CNIO Bioinformatics Unit @bioinformatics.cnio.es · 30/04/2026
🚀 Ya está abierto el plazo de preinscripción del 10º Máster en Bioinformática y Ciencias de Datos en Medicina Personalizada de Precisión y Salud. Formación teórico-práctica en programación, tecnologías multiómicas, IA y salud digital con datos reales. ℹ️ masterbioinformatica.com ¡Plazas limitadas!
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Stephen Turner @stephenturner.us · 02/03/2026
Démodé (2013) www.nature.com/articles/nph.... This short story imagines a future where AI systems designed to read and write scientific papers begin evolving on their own. At first, they help, running massive meta-analyses and accelerating discovery. Then they stop writing for us. 1/🧵
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Glenn K. Lockwood @glennklockwood.com · 04/02/2026
To be fair, this is how all the biggest AI infrastructure providers are bankrolling their growth: Google/Meta fund capex through their ads, Microsoft through Windows licenses. Now xAI has that sweet Starlink revenue. But I don't think Starlink has the margins that software/ads do.
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CNAG @cnag-eu.bsky.social · 29/01/2026
🧬¿Conoces El Proyecto Genoma Humano? Te invitamos a conocer uno de los hitos que ha marcado la ciencia, de la mano de expertos como la Dra. Encarna Guillén (@sjdhospitalbarcelona.org) que nos descubrirá su impacto en la medicina de precisión 🔗 Registro: www.cnag.eu/events/el-pr...
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BSC-CNS @bsc-cns.bsky.social · 12/01/2026
🌐Alfonso Valencia sobre la nueva función de #OpenAI con la que impulsa a sus usuarios a compartir su historia clínica con #ChatGPT: "Va a cometer errores, a generar malas interpretaciones y a poner al doctor en una posición complicada".
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Chanda Prescod-Weinstein 🌌 @chanda.blacksky.app · 08/01/2026
FOR THE LOVE OF ALL THAT IS GOOD IN THE UNIVERSE PLEASE DO NOT USE THIS THANK YOU FOR YOUR ATTENTION TO THIS MATTER www.theverge.com/ai-artificia...
theverge.com
OpenAI launches ChatGPT Health, encouraging users to connect their medical records
But it’s ‘not intended for diagnosis or treatment.’
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cniostopcancer.bsky.social @cniostopcancer.bsky.social · 22/12/2025
These days CNIO personal spontaneusly decorate corridors, labs, the cafeteria... And some of them have even shared ther musical talent in the first New Year Concert, filled with best wishes for the Christmas Season and for 2026  ✨ More info: bit.ly/3KJJW69
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CNIO Bioinformatics Unit @bioinformatics.cnio.es · 26/11/2025
#PorLaCiencia que hacemos en @cniostopcancer.bsky.social
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Reposted by Tomás Di Domenico
CNIO Bioinformatics Unit @bioinformatics.cnio.es · 26/11/2025
#PorLaCiencia que hacemos en @cniostopcancer.bsky.social.
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Reposted by Tomás Di Domenico
CNIO Bioinformatics Unit @bioinformatics.cnio.es · 24/11/2025
📣 We are hiring a Postdoc in @bioinformatics.cnio.es at @cniostopcancer.bsky.social! 🔬 Cancer genomics, NGS, single-cell & spatial transcriptomics 💻 R/Bioconductor, Python, Linux HPC 🇬🇧 Fluent English 📩 Send your CV with Ref: AIPOSBIOINFCAM25II to empleo@cnio.es ℹ️ Full info: tinyurl.com/4hcskvtt
cnio.es
Postdoctoral Research Assistant for the Bioinformatics Unit
DescripciónThe Bioinformatics Unit within the Cancer Genomics programme is seeking to recruit a highly motivated and talented post-doctoral bioinformatician. The selected candidate will work in the co...
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Reposted by Tomás Di Domenico
Stephen Turner @stephenturner.us · 13/11/2025
The Drain of Scientific Publishing arxiv.org/abs/2511.04820
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Reposted by Tomás Di Domenico
Champi @jpascualanaya.bsky.social · 30/10/2025
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch! 📅 Starting date early 2026, with some flexibility. 🙏Please, RT!
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cniostopcancer.bsky.social @cniostopcancer.bsky.social · 30/10/2025
La 'biología del big data' ya ajusta más las terapias a cada paciente.  300 especialistas han presentado sus últimos avances en las XV Jornadas de Bioinformática #JBI2025 (Madrid). Organizadores:  @bioinformatics.cnio.es, INB/ELIXIR-ES @cnb-csic.bsky.social y @biodata.pt 
bit.ly
La revolución de la bioinformática: descifrar el código de la vida para hacer realidad la medicina personalizada
En biología, descubrir ya no es lo que era. La investigación húmeda, de microscopio y pipeta, ya casi no existe sin la de silicio: programas informáticos que extraen la información oculta en un mar de datos. Esta disciplina en auge, la bioinformática, es la que ayuda a entender qué hace cada variante genética, cada proteína: […]
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EMBL-EBI @ebi.embl.org · 27/10/2025
Learn more in the open access Nature Genetics paper: www.nature.com/articles/s41...
nature.com
Complete genome assemblies of two mouse subspecies reveal structural diversity of telomeres and centromeres - Nature Genetics
Telomere-to-telomere assemblies of two mouse inbred strains, C57BL/6J and CAST/EiJ, offer improvements over the current mouse reference genome by adding telomere and centromere sequences that lead to ...
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Reposted by Tomás Di Domenico
Stephen Turner @stephenturner.us · 22/10/2025
What a time to be alive
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Reposted by Tomás Di Domenico
cniostopcancer.bsky.social @cniostopcancer.bsky.social · 13/10/2025
La Fundación Instituto Roche ofrece 4 becas de formación para cursar este máster. Suponen el 80% de la matrícula y este año las han conseguido David Dueñas, Jorge Santos, Mario López y Sofía Trigo.  ¡Enhorabuena! #CienciaDatosMPP #MPP
bit.ly
El máster que ha impulsado la bioinformática en España se enfoca en la medicina personalizada de precisión
Todos los avances médicos y de investigación de las últimas décadas se sustentan sobre una capacidad humana recientemente adquirida: extraer información valiosa de cantidades ingentes de datos. Es lo que hace la bioinformática, en sí misma un área de investigación cada vez más importante y que en los últimos años también crece de forma sinérgica […]
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BSC-CNS @bsc-cns.bsky.social · 13/10/2025
🔘Nueva edición del Máster de Bioinformática del BSC, @cniostopcancer.bsky.social, @saludisciii.bsky.social ciii.bsky.social y SEBiot ▶ Codirigido por Fatima Al-Shahrour y @alfonsovalencia.bsky.social, es el segundo en el mundo con la certificación de la @iscb.bsky.social ➡ lnkd.in/gQcwWzi
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MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 08/10/2025
John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died. Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology. More: www2.mrc-lmb.cam.ac.uk/john-gurdon-... #LMBNews
Black and white portrait of John Gurdon, 1971
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Tomás Di Domenico @tdido.eu · 07/10/2025
What's the deadline for submitting proposals?
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Reposted by Tomás Di Domenico
Roger Castells @rcastellsg.bsky.social · 05/10/2025
We’re looking for an enthusiastic postdoc to join our team. 😊 The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪 The position is fully funded for 3 years. Please share 🙏 Job description and application details (deadline: October 11th): www.cnio.es/en/empleo/po...
cnio.es
Postdoctoral Research Assistant for the Biomolecular Design and Structural Nanomedicine Group
DescriptionWe are looking for a Postdoctoral Researcher to join Roger Castells-Graells’ lab at the Spanish National Cancer Research Centre (CNIO). The successful candidate will work on innovative biom...
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CNIO Bioinformatics Unit @bioinformatics.cnio.es · 08/09/2025
⏰ ¡Última semana para inscribirse en el Máster de Bioinformática del ISCIII! ¡Aún estas a tiempo! ℹ️ masterbioinformatica.com 📌 Organizado por el @saludisciii.bsky.social @cniostopcancer.bsky.social @bsc-cns.bsky.social 🏅 Acreditación oficial @iscb.bsky.social 🤝 Colaboran SEBiot e Instituto Roche
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Andrej Spiridonov @andrejpaleo.bsky.social · 13/08/2025
The grave risks for science as the whole of leaving fundamental scientific infrastructure in the hands of for-profit capitalist company. Essential scholarly services should be internationally curated by value-based societies/orders/colleges. 🧪
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Reposted by Tomás Di Domenico
hpc.social on BlueSky @hpc.social · 07/08/2025
New #HPC Job! 😎️ HPC Engineer Location: Madrid, Spain Employer: Spanish National Cancer Research Centre Remote: Remote friendly
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Tomás Di Domenico @tdido.eu · 28/07/2025
If you ever thought banking apps blocking you if you don't have a Google account was frustrating, imagine a world where the EU blocks you from accessing resources unless you accept Google's ToS... github.com/eu-digital-i...
github.com
Do not add Google Play Integrity integration · Issue #10 · eu-digital-identity-wallet/av-app-android-wallet-ui
In the README, the following is listed: App and device verification based on Google Play Integrity API and Apple App Attestation I would like to strongly urge to abandon this plan. Requiring a depe...
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Tomás Di Domenico @tdido.eu · 17/07/2025
At @bioinformatics.cnio.es, we're looking for an HPC engineer to help us boost the scientific computing infrastructure at @cniostopcancer.bsky.social. Apply or get in touch for more details! www.cnio.es/empleo/advan...
cnio.es
Advanced Degree for the Bioinformatics Unit
DescripciónThe Bioinformatics Unit within the Cancer Genomics programme is seeking to recruit a highly a highly motivated and talented High-Performance Computing (HPC) expert specialized in scientific...
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CNIO Bioinformatics Unit @bioinformatics.cnio.es · 15/07/2025
🔔 Abierto el 2º plazo de preinscripción del Máster en Bioinformática del ISCIII 🧬 Aún nos quedan plazas...¡pero son limitadas! 📆 ¡No pierdas la oportunidad! ¡Aún estás a tiempo! 📚 Organizado por @saludisciii.bsky.social @cniostopcancer.bsky.social @bsc-cns.bsky.social 👉 masterbioinformatica.com
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Carl T. Bergstrom @carlbergstrom.com · 25/06/2025
A few months ago, Nature published how-to guide for using ChatGPT to write your peer reviews in 30 minutes. This is, of course, a horrible idea. Here’s my response with @jbakcoleman.bsky.social .
nature.com
AI, peer review and the human activity of science
When researchers cede their scientific judgement to machines, we lose something important.
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James Vincent @jjvincent.bsky.social · 22/05/2025
clear, depressing set of observations from @randomwalker.bsky.social - "The decline of reading-for-pleasure (due to video) and reading-for-information (due to AI) will accelerate each other, as reading text without an intermediary will come to be seen as a chore."
"A hypothesis on the accelerating decline of reading:  

* Broadly speaking, people read for pleasure/entertainment and for learning/obtaining information. 
* Reading for pleasure has been declining for a while and is being replaced by videos (very sharply among young people). This trend will surely continue. 
* Reading for obtaining information is getting intermediated by chatbots. We are in the very early stages of this shift, so I think people underappreciate the magnitude of what's coming. It's not just that AI replacing traditional web search. Even when it comes to reading news articles, business documents, or scientific papers, the vision that tech companies are pushing on us is AI summarization + synthesis + Q&A. 
* We don't have to accept this, but I predict that most people will. It's a tradeoff between speed/convenience and accuracy/depth of understanding — the same tradeoff that was once offered to us when it became possible to search the web to look up a quick fact as opposed to reading about the topic in depth in an encyclopedia. 
* Just as most people in most cases prefer a shallow web search over deeper reading, most people in most cases will prefer AI-intermediated access to knowledge. Traditional reading won't disappear, but people will do it vastly less often, except in hobbyist reading communities and professions where traditional reading is needed. 
* The decline of reading-for-pleasure (due to video) and reading-for-information (due to AI) will accelerate each other, as reading text without an intermediary will come to be seen as a chore. 
* Personally, I find this sad. But while it's tempting to moralize all this, I think that's unproductive. Yelling at individuals to resist new media has been done for centuries and has never worked. 
* Even if people individually rationally choose these tradeoffs, I think we collectively lose something; critical reading skills are arguably essential for a democracy. We need to figure out what to do about that.
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Navin B. Ramakrishna @navinbr.bsky.social · 14/05/2025
Glad to see this out, and to have contributed in a miniscule way to what will hopefully be an excellent resource: long read assemblies of 17 strains of mice www.biorxiv.org/content/10.1...
biorxiv.org
The mouse pangenome reveals the structural complexity of the murine protein coding landscape
We present the first mouse pangenome consisting of 17 high-quality inbred mouse strain genomes with complete annotation. This collection includes 12 widely used classical laboratory strains and 5 wild...
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Reposted by Tomás Di Domenico
CNIO Bioinformatics Unit @bioinformatics.cnio.es · 12/05/2025
¡Abierta la preinscripción del Máster en Bioinformática y Ciencias de Datos en Medicina Personalizada de Precisión y Salud 2025/26! 📍Organizan: @saludisciii.bsky.social @cniostopcancer.bsky.social @bsc-cns.bsky.social 🤝 Colaboran: SEBiot,Instituto Roche 📅 Plazas limitadas 🔗 masterbioinformatica.com
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CNIO Bioinformatics Unit @bioinformatics.cnio.es · 23/04/2025
🚀 Registration and abstract submissions are NOW OPEN for #JBI2025! 🗓️ Oct 22–24, 2025, in Madrid, Spain 🤝 Spain and Portugal #Bioinformatics and #ComputationalBiology communities 📰 Submit your work: abstract for talk/poster and highlight papers 🔗 jbi2025.cnb.csic.es
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Tomás Di Domenico @tdido.eu · 22/04/2025
I started experimenting with @nanoporetech.com long-read sequencing technology more than 10 years ago. A couple of years back it became my main focus, and we finally have our first results out: www.medrxiv.org/content/10.1...
medrxiv.org
Multi-Omic Profiling Reveals Epigenetic Drivers of Immunotherapy Resistance in Multiple Myeloma
Targeted immunotherapies against B-cell maturation antigen (BCMA) have transformed the treatment landscape of Multiple Myeloma (MM). Fc receptor-like 5 (FCRL5) has emerged as an alternative target. Ho...
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Tomás Di Domenico @tdido.eu · 26/03/2025
When the first (promising) image-generating models appeared a few years ago I thought that maybe ~10 years later we'd be able to prompt our way into fixing the disaster that Episode IX was. I think my prediction may not be too far off.
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Tomás Di Domenico @tdido.eu · 26/03/2025
Imagine if we had just a fraction of those "savings" invested in OSS projects. What a world that would be.
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Tomás Di Domenico @tdido.eu · 26/03/2025
"We estimate the supply-side value of widely-used OSS is $4.15 billion, but that the demand-side value is much larger at $8.8 trillion. We find that firms would need to spend 3.5 times more on software than they currently do if OSS did not exist." simonwillison.net/2025/Mar/26/...
simonwillison.net
A quote from Manuel Hoffmann, Frank Nagle, Yanuo Zhou
We estimate the supply-side value of widely-used OSS is $4.15 billion, but that the demand-side value is much larger at $8.8 trillion. We find that firms would need to spend …
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Tomás Di Domenico @tdido.eu · 16/03/2025
Gemini didn't want to play ball at first. It took some convincing.
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Tomás Di Domenico @tdido.eu · 16/03/2025
As a kid I learned about extinction through dodos. I use "Where are the dodos?" as first contact with every new LLM I try. When I read about @simonwillison.net's cycling pelicans benchmark, I decided to try my own: juggling dodos. Then I asked Claude for a gallery to display them: dodos.tdido.eu
dodos.tdido.eu
Juggling Dodos Gallery
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Simon Willison @simonwillison.net · 14/02/2025
Quick TIL: if you have uv installed and you want to try out ANY Python package in an ipython REPL, you can do so just by running uvx --with llm --with sqlite-utils ipython Pass as many --with package options as you like I wrapped it in a shell script, "itry llm" til.simonwillison.net/python/itry
til.simonwillison.net
Trying out Python packages with ipython and uvx
I figured out a really simple pattern for experimenting with new Python packages today:
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Arvind Narayanan @randomwalker.bsky.social · 10/02/2025
One of the biggest areas of AI hype right now is the notion that it will hyperaccelerate scientific progress. I understand why people think this — AI is already accelerating scientific _production_. 🧵
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Simon Willison @simonwillison.net · 07/02/2025
If you have uv installed this means you can start chatting with a small model without first installing anything at all - this command will create an ephemeral virtual environment, install the necessary pieces and start a chat UI running in your terminal: uvx --with llm-smollm2 llm chat -m SmolLM2
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