Sign in

Takumi Matsuzawa

@takumimatz.bsky.social
70 followers 174 following 22 posts

Schmidt Science Fellow in Dufresne lab at Cornell University, studying biomolecular condensates | Turbulence | Vortex dynamics | Liquid-liquid phase separation

PostsRepliesMedia
Reposted by Takumi Matsuzawa
Laboratory of Soft and Living Materials @SoftLiv_Cornell @softliv.bsky.social · 06/08/2026
Our new paper is out! We asked how small molecules influence biomolecular condensation. Our findings help identify molecules and rxns that regulate physiology and inform therapeutic development. Susceptibility and regulation of biomolecular condensates by solutes | PNAS www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
174
Reposted by Takumi Matsuzawa
Shahar Sukenik @shaharsu.bsky.social · 29/07/2026
Finally out - our work on high throughput design and characterization of disordered protein sequences 🪱🪱🪱. A long time collaboration with BFFs @alexholehouse.bsky.social and @remenecker.bsky.social, with experimental work led by @trevorbrandt.bsky.social and @karaehunt.bsky.social.
nature.com
Rational design of disordered proteins for sequence–function investigation - Nature
GOOSE enables the design and testing of thousands of disordered protein region sequences to reveal distinct sequence-to-function relationships.
2178
Takumi Matsuzawa @takumimatz.bsky.social · 28/02/2026
Here’s another condensate paper from the lab. We revisit biomolecular condensation—phase separation in protein suspensions—through the lens of critical phenomena. Kaarthik did excellent work characterizing mechanical properties and comparing their scaling behavior to the 3D Ising universality class.
072
Takumi Matsuzawa @takumimatz.bsky.social · 28/02/2026
Here’s my recent work on biomolecular condensates. In this paper, we address how small molecules shift the phase equilibria of condensates. We describe how underlying protein–solute interactions determine the observed shifts and develop a theoretical framework using standard thermodynamic theory.
030
Reposted by Takumi Matsuzawa
Proceedings of the National Academy of Sciences @pnas.org · 19/02/2026
In this issue: A parasite drives movement in infected red blood cells, electric charges can accelerate without emitting radiation, and stratospheric methane loss. In PNAS: ow.ly/c6bK50Yi61j
Pictured are 3D trajectories of turbulent particles colored by speed, showing two large vortices.

Image credit: Takumi Matsuzawa.
042
Reposted by Takumi Matsuzawa
Mattia Serra @mattiaserra.bsky.social · 19/09/2025
📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia. @sreejithsanthosh.bsky.social biorxiv.org/content/10.1...
17619
Takumi Matsuzawa @takumimatz.bsky.social · 19/02/2026
Ever had to wait at the airport even though your plane is already at the gate? That’s because the turbulence from earlier traffic needs to die down before the next takeoff. Our latest work in PNAS (on cover!) tackles this question of how turbulence decays and spreads. www.pnas.org/doi/10.1073/...
110
Takumi Matsuzawa @takumimatz.bsky.social · 19/02/2026
The word is out! The blob is back on the cover! I'm grateful to my mentors, William and Nigel @nigelgoldenfeld.bsky.social, and to Minhui @minhui-zhu.bsky.social, who performed the essential calculations. This work wouldn't have been possible without any one of us. Congratulations to the team!
030
Reposted by Takumi Matsuzawa
D. Allan Drummond @dadrummond.art · 26/08/2025
Monarchs (Danaus plexippus) are still feeding on the obedient plant blossoms (Physostegia virginiana), though not quite in the numbers they were a few days ago. Here’s an experienced aviator drinking deeply. #InverteFest
A monarch butterfly whose wings bear the signs of thousands of beats feeding at an obedient plant blossom. The blossoms grow in columns and are bright pink with an open-mouthed appearance.
0535
Reposted by Takumi Matsuzawa
Laboratory of Soft and Living Materials @SoftLiv_Cornell @softliv.bsky.social · 25/08/2025
Two weeks ago the Softliv crew was at the 2025 Soft Condensed Matter GRC! 🍃 We shared our ongoing research, learned a ton from the community, and enjoyed many energizing discussions. A highlight was reconnecting with our amazing lab alumni — nothing beats mixing science with good company! 💡👥
152
Reposted by Takumi Matsuzawa
Schmidt Science Fellows @schmidtfellows.bsky.social · 01/07/2025
“When we set our sights on doing the impossible, that is when we are at our best". An inspiring message from former JPL director Laurie Leshin sets the tone for our Showcase Day at the Interdisciplinary Science Summit! In association with @caltech.edu Thank you!
021
Takumi Matsuzawa @takumimatz.bsky.social · 15/03/2025
If you are attending #APSSummit25 next week, check out the talks from my postdoc lab! Kaarthik will present critical fluctuations of liquid-liquid phase separation. More details in the original post. #LLPS #APS #condensates
010
Takumi Matsuzawa @takumimatz.bsky.social · 28/01/2025
Activity can drive flows: self-driven spinners reveal states from chiral active fluids to twisters. 🌪️ Amazing work led by Panyu, Scott, and Severine. It was a joy to watch the experiments unfold and analyze the flows together. Check out the cover to see how the spinners dance!
020
Takumi Matsuzawa @takumimatz.bsky.social · 07/01/2025
Important point to spread science
020
Reposted by Takumi Matsuzawa
Hyman Lab @hymanlab.bsky.social · 07/01/2025
How do molecules diffuse across phase boundaries in liquid droplets? Find out in Lars' epic work in the preprint on @biorxivpreprint.bsky.social @larshubatsch.bsky.social !!! @hymanlab.bsky.social @mpipks.bsky.social collaboration of Hymanlab, Frank Juelicher group and Chris Weber in Augsburg
0111
Reposted by Takumi Matsuzawa
RCSB Protein Data Bank @rcsbpdb.bsky.social · 06/01/2025
After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month. We are very grateful for his service. @jiwasa.bsky.social will continue the series, beginning with January's article on Assembly Line Polyketide Synthases Details: cdn.rcsb.org/rcsb-pd...
cdn.rcsb.org
EDUCATION CORNER: Molecule of the Month: Celebrating  25 Years of Storytelling and Announcing New Beginnings
After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month series.  Janet Iwasa will be continuing the series for PDB-101.
213643