www.biorxiv.org/content/10.6...
Excited to share our new preprint with Juliette Azimzadeh’s lab! The paper shows the linkers connecting the two basal bodies at the primary cilium are not rootlets, but a distinct set of asymmetrically localised centrosomal proteins, including my favourite CCDC61✨
biorxiv.org
Rotational asymmetry is required to position centrioles at the base of the primary cilium
The polarization of motile cilia requires that the centrioles, from which cilia are formed, display rotational asymmetry. This property is manifested in the presence of asymmetrically distributed appe...