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Takashi Ochi (Leeds)

@takashiochi.bsky.social
703 followers 475 following 12 posts

Group leader @ University of Leeds interested in protein structures, centrosomal/ciliary biology and DSB repair in plants, and love coffee/whisky/cycling/vinyls. Views my own.

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Takashi Ochi (Leeds) @takashiochi.bsky.social · 13/07/2026
www.biorxiv.org/content/10.6... Excited to share our new preprint with Juliette Azimzadeh’s lab! The paper shows the linkers connecting the two basal bodies at the primary cilium are not rootlets, but a distinct set of asymmetrically localised centrosomal proteins, including my favourite CCDC61✨
biorxiv.org
Rotational asymmetry is required to position centrioles at the base of the primary cilium
The polarization of motile cilia requires that the centrioles, from which cilia are formed, display rotational asymmetry. This property is manifested in the presence of asymmetrically distributed appe...
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Reposted by Takashi Ochi (Leeds)
Helen Foster @helenfoster.bsky.social · 11/06/2026
There are lots of exciting opportunities to join the in situ structural biology community at Leeds this Autumn - 2 studentships in the Cheney PhD program (astbury.leeds.ac.uk/cheney-phd/) and I am recruiting a PhD student and research assistant. Please share and send any future tomographers our way!
astbury.leeds.ac.uk
Cheney Scholarship PhD Programme : The Astbury Centre for Structural Molecular Biology - "Understanding Life in Molecular Detail"
Applications are open for 2 PhD student places.  Closing date for applications is Thursday 26 June, 5pm. Interviews will be held on 9th July 2026. The Cheney Scholarship is a prestigious 4-year PhD pr...
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Mill_lab @cilialab.bsky.social · 27/05/2026
Still time to register to join us next Friday in Leeds for our annual in-person UK Cilia and Centrosome Network in Leeds (05/06/2026)! Keynotes from the amazing @helenfoster.bsky.social & Fanni Gergely, plus latest breaking #cilia & #centrosome science. Register: www.eventbrite.co.uk/e/uk-cilia-c...
eventbrite.co.uk
UK Cilia & Centrosomal Network Meeting Spring Meeting 2026
Join us for the annual in-person meeting of the UK Cilia & Centrosomal Network meeting, which for 2026 will be at the University of Leeds!
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Takashi Ochi (Leeds) @takashiochi.bsky.social · 07/02/2026
Beautiful structures and mind-blowing discovery!
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Reposted by Takashi Ochi (Leeds)
The EMBO Journal @embojournal.org · 28/01/2026
See also the great News&Views comment by Monica Gobran and @plenart.bsky.social - highlighting all three papers! link.springer.com/article/10.1...
link.springer.com
Mitotic entry: Bora takes Polo to Aurora, and gives them a hug - The EMBO Journal
The EMBO Journal - Cell division involves the complete reorganization of the cellular architecture, requiring precise coordination of cellular processes in space and time, but how does this control...
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Takashi Ochi (Leeds) @takashiochi.bsky.social · 27/09/2025
www.nature.com/articles/s41... Interstasis, an impressive discovery! It kind of explains some of the odd behaviours of CCDC61, which can actually crystallise in cells when it’s overexpressed. It is a liquid-solid phase separation….
nature.com
Collective homeostasis of condensation-prone proteins via their mRNAs - Nature
The authors discover a homeostatic process termed interstasis, in which an increased concentration of proteins within RNA–protein condensates induces the sequestration of their own mRNAs.
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Takashi Ochi (Leeds) @takashiochi.bsky.social · 08/08/2025
Chlamy Hello Kitty at the Japan Pavilion Osaka Expo 2025
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Garvin SUMO Biology Lab @garvinlab.bsky.social · 13/03/2025
It's finally out in @cp-molcell.bsky.social. Huge thanks to @leneyms.bsky.social and team Morris @themorrislab.bsky.social for getting this SUMO4 story over the finish line! SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair: Molecular Cell www.cell.com/molecular-ce...
cell.com
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
Garvin et al. find that the poorly explored SUMO isoform, SUMO4, enhances the deSUMOylation activity of the SUMO protease SENP1. Consequently, SUMO4 acts to restrain excessive cellular SUMOylation. In...
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Reposted by Takashi Ochi (Leeds)
Alan Brown @alanbrownhms.bsky.social · 02/01/2025
A reminder that the Brown lab has an opening for a postdoc fellow: brown.hms.harvard.edu/jobs/242. This might suit someone from the #cilia community interested in learning structural biology. Deadline extended to the 10th Jan.
brown.hms.harvard.edu
Postdoctoral fellow | Brown Lab
The Brown lab at Harvard Medical School is seeking a highly motivated postdoctoral fellow to join our team.
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Reposted by Takashi Ochi (Leeds)
Yehuda Halfon @yushuv.bsky.social · 11/12/2024
In Feb 2025 we will host a Virtual Wellcome - Advanced SPA Cryo-EM Course. The course will be for PhD student, postdoc, staff scientist or young group leaders. If you think it will benefit you go to the website for more info: astbury.leeds.ac.uk/facilities/w... Sharing will be appreciated :-)
astbury.leeds.ac.uk
Advanced Single Particle Cryo-EM Course – February 2025 : The Astbury Centre for Structural Molecular Biology
Course overview The course is a part of the Wellcome Trust and MRC funded Cryo-EM Training Program that offers an intensive learning opportunity tailored to PhD students, postdocs, and early-career sc...
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Reposted by Takashi Ochi (Leeds)
Susana Godinho @susanagodinho.bsky.social · 11/12/2024
We have a very cool (I know I am biased😁) project for a computational biologist (postdoc) interested in cancer evolution in collaboration with Nicky McGranahan’s lab! Perfect opportunity to expand your computational skills too! 👉 www.godinholab.com RT please 🙏🙏🙏👍👍
godinholab.com
Godinho Lab
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Reposted by Takashi Ochi (Leeds)
Julie @rna-julie.bsky.social · 26/11/2024
Delighted to be advertising 2 exciting PhD projects 1) lncRNA derived micropeptides & their contribution to brain cancers with James Poulter & Lucy Stead 2) mechanisms of translational regulation by specialised ribosomes. @chillzaa.bsky.social & Ade Whitehouse www.findaphd.com/phds/?Keywor...
findaphd.com
aspden PhD Projects, Programmes & Scholarships
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in aspden. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
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Reposted by Takashi Ochi (Leeds)
samlacey.bsky.social @samlacey.bsky.social · 18/11/2024
Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps. www.nature.com/articles/s41...
nature.com
The intraflagellar transport cycle - Nature Reviews Molecular Cell Biology
Intraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili...
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Takashi Ochi (Leeds) @takashiochi.bsky.social · 23/11/2024
Fantastic meeting with a great memorial talk for David Stephens by Anthony Roberts. There were also many stimulating talks by ECRs and Elif Nur Firat-Karalar. Thanks for @urszulamcclurg.bsky.social for organising this event in Liverpool!
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Takashi Ochi (Leeds) @takashiochi.bsky.social · 21/11/2024
Funded PhD structural plant biology project focusing on understanding DNA double-strand break repair in plants! This project is a part of the Yorkshire Bioscience Doctoral Training Partnership and in collaboration with Chris West (Leeds). www.findaphd.com/phds/project...
findaphd.com
Structural studies of DNA double-strand break repair in plants at University of Leeds on FindAPhD.com
PhD Project - Structural studies of DNA double-strand break repair in plants at University of Leeds, listed on FindAPhD.com
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Reposted by Takashi Ochi (Leeds)
Neil Ranson @naranson.bsky.social · 18/11/2024
I am about to be recruiting two post-docs to work on cryoEM and cryoET of amyloid aggregates... Anyone interested please drop me a line while the wheels of our HR department turn.............
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