Sign in

Sumedha Nalluru

@sumedhanalluru.bsky.social
82 followers 88 following 7 posts

PhD candidate w/ Helen Barron and Jill O’Reilly at NDCN, University of Oxford. Interested in cognitive maps, memory and psychosis.

PostsRepliesMedia
Reposted by Sumedha Nalluru
Neil Burgess @neilburgess10.bsky.social · 08/08/2026
Great to see Ellie Spens’ model out! Interplay btwn episodic (hippo) & semantic (neocort’l) systems, in encoding, consolidatn, recall & problem solving with sequential info, as compressive retrieval-augmented generation. Inc gist-based distortion in stories & inference www.nature.com/articles/s41...
nature.com
Hippocampo-neocortical interaction as compressive retrieval-augmented generation - Nature Communications
Here the authors model interactions between episodic and semantic memory as ‘retrieval-augmented generation’, explaining consolidation of structure from sequential experience, the reconstruction and d...
02810
Reposted by Sumedha Nalluru
Helen Barron @helencbarron.bsky.social · 28/07/2026
***New preprint from the lab*** showing “Generative replay across hippocampal-neocortical circuits”. In sleep we show spiking sequences in V1 (sensory neocortex!) that represent information that has not been directly experienced www.biorxiv.org/content/10.6... @bndu.ox.ac.uk @ndcnoxford.bsky.social
biorxiv.org
Generative replay across hippocampal-neocortical circuits
To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...
413463
Reposted by Sumedha Nalluru
Ivan Tomic @ivntmc.bsky.social · 10/06/2026
Feeling really proud of this one: a review of Bayesian efficient coding with Máté Lengyel and Paul Bays (@bayslab.org) is now available online in TICS! authors.elsevier.com/a/1nF3i4sIRv...
Screenshot of a Trends in Cognitive Sciences article header. Title: 'Bayesian efficient coding as a theory of perception: progress, controversies, and prospects.' Authors: Ivan Tomić, Máté Lengyel, Paul Bays. Available online 9 June 2026, In Press, Corrected Proof.
39334
Reposted by Sumedha Nalluru
Rochelle Kaper @rochellekaper.bsky.social · 24/07/2026
plane read🤓! shoutout @sumedhanalluru.bsky.social & all for this very cool piece🧠
0111
Reposted by Sumedha Nalluru
Helen Barron @helencbarron.bsky.social · 10/07/2026
New perspective paper from our lab: “The hippocampus as a generative model” out now !! royalsocietypublishing.org/rstb/article... The traditional view of the hippocampus is that it creates a cognitive map. Here we extend this view to conceptualise the hippocampus as a “generative model”.
royalsocietypublishing.org
The hippocampus as a generative model
Abstract. A generative model can be defined as a model of the latent causes of sensory input that can be used to generate new data samples. By examining em
15522
Reposted by Sumedha Nalluru
Helen Barron @helencbarron.bsky.social · 09/07/2026
It was a pleasure to be able to contribute to this exciting special issue with @sumedhanalluru.bsky.social @glitzleonie.bsky.social @xenianeuro.bsky.social and Valentina Mancini. Thanks to @peterkok.bsky.social @mariamaly.bsky.social @barense.bsky.social for putting it together!
0183
Reposted by Sumedha Nalluru
peterdoohan.bsky.social @peterdoohan.bsky.social · 11/06/2026
How do brains plan actions towards goals? To get at this question we studied mice navigating complex mazes as goals changed on every trial 🧵 Work with @thomasakam.bsky.social @behrenstimb.bsky.social @kristorpjensen.bsky.social now on BioRxiv: www.biorxiv.org/content/10.6...
411846
Reposted by Sumedha Nalluru
Helen Barron @helencbarron.bsky.social · 20/03/2026
*** New paper from the lab in Nature Comms !! *** “Noradrenaline causes a spread of association in the hippocampal cognitive map” by the amazing @reneecabbage.bsky.social in collab. w labs of Jill O’Reilly, Will Clarke, and modeling from Prakriti Parthasarathy and @tpvogels.bsky.social, see below!
04915
Reposted by Sumedha Nalluru
Renée Koolschijn @reneecabbage.bsky.social · 20/03/2026
Very pleased to share that our study “Noradrenaline causes a spread of association in the hippocampal cognitive map” is out in @natcomms.nature.com (my final PhD paper, only 3.5 years post PhD! 🙃) Find the paper here: www.nature.com/articles/s41...
nature.com
Noradrenaline causes a spread of association in the hippocampal cognitive map - Nature Communications
When forming a cognitive map, a trade-off exists between facilitating novel inferences and storing veridical copies of past experience. Here the authors show that the neuromodulator noradrenaline sets...
13413
Reposted by Sumedha Nalluru
Helen Barron @helencbarron.bsky.social · 12/03/2026
At #cosyne2026? Check out Sumedha Nalluru’s poster from our lab! Showing that reduced cortical inhibition causes false associations. Friday 13th March from 1:15 - 4:15pm.
192
Reposted by Sumedha Nalluru
Leonie Glitz @glitzleonie.bsky.social · 16/02/2026
Interested in cognitive maps? Wondering how you should best train your participants? Luckily for you, we have investigated just that! Very excited to share a preprint from my PhD in which we show how initial training curriculum affects the cognitive maps we form osf.io/preprints/ps... [1/6]
osf.io
OSF
1295
Reposted by Sumedha Nalluru
Blake Russell @neurorussell.bsky.social · 26/01/2026
Out today in Neurophotonics, we show that cross-talk between the imaging laser and opsin in all-optical experiments can affect response dynamics beyond what has been accounted for. Imaging conditions subthreshold for evoking spikes can accelerate opsin desensitization: doi.org/10.1117/1.NP...
doi.org
135
Reposted by Sumedha Nalluru
Lisa Spiering @lspiering.bsky.social · 21/01/2026
🎉 My PhD work has just been published in @natcomms.nature.com! How do we learn who caused what - and how much control we had - when outcomes depend on multiple people? We studied how humans do so using a new social learning task, computational modelling and fMRI. www.nature.com/articles/s41... 🧵👇
16222
Reposted by Sumedha Nalluru
Sebastijan Veselic @sebves.bsky.social · 15/11/2025
1/ Excited to share that our symposium review covering cognitive mapping in the PFC just came out in the Journal of Neuroscience: www.jneurosci.org/content/45/4...
jneurosci.org
Cognitive Maps in the Prefrontal Cortex
The prefrontal cortex (PFC) is critical for our ability to rapidly and flexibly adapt our behavior in new environments based on our previous experience. Despite its importance, the neural substrates a...
1129
Reposted by Sumedha Nalluru
Helen Barron @helencbarron.bsky.social · 06/10/2025
** We have up to TWO funded PhD positions available in our lab!! Apply below to find new ways to enhance memory👇 Pls retweet ** Deadline: 2nd December 1. Cross-species closed-loopTMR: tinyurl.com/bddu4tp6 2. TUS and TMR in humans: tinyurl.com/jjws5ctj Happy to chat to interested applicants.
tinyurl.com
Enhancing memory using cross-species closed-loop Targeted Memory Reactivation | mrcbndu
15046
Reposted by Sumedha Nalluru
Manfredi Castelli @manfredic.bsky.social · 02/10/2025
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social ! With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
47128
Reposted by Sumedha Nalluru
Kris Jensen @kristorpjensen.bsky.social · 24/09/2025
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time! www.biorxiv.org/content/10.1...
922286
Reposted by Sumedha Nalluru
Brain Network Dynamics Unit @bndu.ox.ac.uk · 19/08/2025
New unit paper on “Predictive coding model detects novelty on different levels of representation hierarchy”, published in Neural Computation. www.mrcbndu.ox.ac.uk/papers/predi... @mrcbndu.ox.ac.uk @ndcnoxford.bsky.social @ox.ac.uk
Energy of novel and familiar stimuli
023
Reposted by Sumedha Nalluru
Vitor Lopes dos Santos @vitorlds.bsky.social · 05/06/2025
I'm pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, out in @cp-cellreports.bsky.social ! With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding. (1/13)
15323
Reposted by Sumedha Nalluru
Peter Kok @peterkok.bsky.social · 22/05/2025
Our study using layer fMRI to study the direction of communication between the hippocampus and cortex during perceptual predictions is finally out in Science Advances! Predicted-but-omitted shapes are represented in CA2/3 and correlate specifically with deep layers of PHC, suggesting feedback. 🧠🟦
science.org
Communication of perceptual predictions from the hippocampus to the deep layers of the parahippocampal cortex
High-resolution neuroimaging reveals stimulus-specific predictions sent from hippocampus to the neocortex during perception.
316552
Reposted by Sumedha Nalluru
Jacob Bakermans @bakermansjjw.bsky.social · 17/03/2025
Happy to share the latest version of our work on compositional maps in hippocampus with Jo Warren, @jcrwhittington.bsky.social, @behrenstimb.bsky.social. We propose hippocampus constructs maps from cortical building blocks in replay – now with empirical support! www.nature.com/articles/s41... 1/9
nature.com
Constructing future behavior in the hippocampal formation through composition and replay - Nature Neuroscience
A model of compositional state spaces in the hippocampus shows latent learning and rapid generalization. Bakermans et al. show that this model predicts the emergence of place responses in replay.
18024
Reposted by Sumedha Nalluru
Eleanor Holton @eleanor-holton.bsky.social · 24/02/2025
New preprint out with @summerfieldlab.bsky.social! When does new learning interfere with existing knowledge? We compare continual learning in humans and artificial neural networks, revealing similar patterns of transfer & catastrophic interference (1/8) osf.io/preprints/ps...
16227
Reposted by Sumedha Nalluru
Marcel Binz @marcelbinz.bsky.social · 27/01/2025
We are currently building the largest, cross-domain data set of human behavior as part of an open collaborative project. Contributions of any form are welcome, but especially experiments with meta-data from developmental, cross-cultural, or clinical studies. More details: github.com/marcelbinz/P...
github.com
GitHub - marcelbinz/Psych-201
Contribute to marcelbinz/Psych-201 development by creating an account on GitHub.
23515
Sumedha Nalluru @sumedhanalluru.bsky.social · 13/12/2024
Our paper "Memory reactivation generates new, adaptive behaviours that reach beyond direct experience" is now out www.nature.com/articles/s41...! With Annie Rawson, Jill O’Reilly and Helen Barron at MRC BNDU @ndcnoxford.bsky.social 1/6
14015