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Kira Gritsman

@gritsmanlab.bsky.social
986 followers 1.2K following 21 posts

Physician-scientist studying leukemic stem cells and hematopoiesis #signaling #PTMs #non-genetic resistance mechanisms #microenvironment Associate Professor at Albert Einstein College of Medicine

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Reposted by Kira Gritsman
STEMCELL Science News @stemcellsciencenews.com · 30/09/2026
Presenting new work from Drs. Shira Glushakow-Smith and Kira Gritsman (@gritsmanlab.bsky.social)! @einsteinmededu.bsky.social scientists demonstrate that #AML leukemic stem cells exhibit a selective dependency on PI3Kα. #OpenAccess 🔓 Learn more: go.nature.com/4hFQfnI
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Kira Gritsman @gritsmanlab.bsky.social · 20/07/2026
Excited for another great myeloid workshop at ASH this year! Please send us your most exciting science!
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Kira Gritsman @gritsmanlab.bsky.social · 28/08/2025
Happy to contribute to this exciting project just published in @nature.com led by the amazing Shoichiro Takeishi in a fantastic collaboration with @steidluli.bsky.social - check out this thread 🩸 🧬
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Reposted by Kira Gritsman
Dr. Dawn Wright @deepseadawn.bsky.social · 01/08/2025
Glimmer of hope: the Senate Labor, Health and Human Services Subcommittee just voted, 26 to 3, to reject the administration’s proposed cuts & instead recommend a $400 million increase to the NIH budget. The House LHHS Subcommittee convenes in September www.appropriations.senate.gov/news/minorit... 🧪
appropriations.senate.gov
Senate Appropriations Committee Approves Defense and Labor, Health and Human Services, and Education Bills | United States Senate Committee on Appropriations
United States Senate Committee on Appropriations
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Reposted by Kira Gritsman
Heme Queen @heme-queen.bsky.social · 31/07/2025
So impressed at the increased support the American Society of Hematology is planning for trainees and early-career investigators!! At some point, someone invested in us. Now it’s our turn. #Fight4Hematology and secure the future of hematology research. Donate! #hemesky www.hematology.org/foundation
hematology.org
ASH Foundation
The ASH Foundation is dedicated to moving hematology forward through charitable support for ASH programs – helping hematologists conquer blood diseases worldwide.
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Reposted by Kira Gritsman
American Society of Hematology @ash.hematology.org · 31/07/2025
Interested in a mentor to guide your career in malignant hematology? Apply for the ASH’s new Mentorship Program, and grow your network! Deadline: Sept 26. Apply today! 🔗 bit.ly/3IPWjMA Interested in becoming a mentor? Sign up today: bit.ly/3U5tm1t #HemeSky
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Reposted by Kira Gritsman
ernstlaboratory.bsky.social @ernstlaboratory.bsky.social · 21/07/2025
The Myeloid Workshop is back in ASH! Please contact the organizers if you have an exciting story that will not be out by December they are: Zuzana Tothova , @ernstlaboratory.bsky.social @steidluli.bsky.social @ericpietras.bsky.social @kathrinbernt.bsky.social @gritsmanlab.bsky.social
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Kira Gritsman @gritsmanlab.bsky.social · 16/07/2025
Check out our new preprint on an epigenetic resistance mechanism to PI3 kinase inhibition in AML and a new combination therapy with an EZH1/2 inhibitor that depletes leukemic stem cells! Great effort by @thehematopoet and the whole team
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Kira Gritsman @gritsmanlab.bsky.social · 10/04/2025
So excited that our collaboration with the Shechter lab on a new targetable PTM -glutamylation- on NPM1c in AML is now on BioRxiv! Team effort led by @alexkschurer.bsky.social and @humaira2204.bsky.social! 🧪🩸
humaira2204.bsky.social
Humaira (@humaira2204.bsky.social)
Research Fellow in the Dept. of Biochemistry, Working with Histone Chaperones. @einsteinmed Baking Enthusiast, Book Lover, Webseries Buff 🙃
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Reposted by Kira Gritsman
American Society of Hematology @ash.hematology.org · 21/03/2025
#NIHfunding cuts have resulted in stalled research. In response, ASH is expanding its Bridge Grant Program with $150K in awards to support critical research by members. Donate to support #hematology researchers and help ensure innovative research continues: bit.ly/41LFwjD #HemeSky #MedSky
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Reposted by Kira Gritsman
The Unpatriotic Misanthrope who Protests @vcalemine.bsky.social · 11/03/2025
If you have applied to an R01 or equivalent, please check out the new eligibility. #hematology #medsky #phdsky #scisky #science
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Reposted by Kira Gritsman
Rick Huganir @rhuganir.bsky.social · 15/02/2025
I have been talking to the media, Time, Fortune, NBC, etc., to explain how the onslaught on science and NIH will impact the health of all Americans. Everyone knows someone who has cancer, heart disease, or depression. Spread the word about how cutting science impacts all. time.com/7216299/nih-...
time.com
Experts Call NIH Budget Cuts an 'Apocalypse' for Science
The reductions target indirect costs that cover administrative and equipment costs.
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Reposted by Kira Gritsman
American Society of Hematology @ash.hematology.org · 14/02/2025
📢 Support federal research funding! As the new Administration acts & Congress finalizes FY25 funding, lawmakers need to hear from you. Share your stories of how funding & policies impact #hematology patients & research. Take action! bit.ly/4b2bj43 #Fight4Hematology #HemeSky #BloodSky
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Reposted by Kira Gritsman
American Society of Hematology @ash.hematology.org · 28/01/2025
Calling all aspiring hematologists in med school — don’t leave research funding on the table! 💰 ✨ HIP Medical Student Award ✨ HONORS Award ✨ Physician-Scientist Award Learn more: bit.ly/4hexNk7. Your application is due on Feb. 14! #ASHTrainee #HemeSky #BloodSky #Hematology
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Kira Gritsman @gritsmanlab.bsky.social · 22/01/2025
Congratulations to all the new ASH Scholars!
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Reposted by Kira Gritsman
Ann Mullally @mullallylab.bsky.social · 10/01/2025
Delighted to share our #hematology review article on mutant calreticulin in #MPN Congrats to co-authors Drs. Mifra Faiz, Merle Riedemann & Jonas Jutzi. We hope it’s a useful resource, link below! @stanforddeptmed.bsky.social link.springer.com/article/10.1...
link.springer.com
Mutant Calreticulin in MPN: Mechanistic Insights and Therapeutic Implications - Current Hematologic Malignancy Reports
Purpose of Review More than a decade following the discovery of Calreticulin (CALR) mutations as drivers of myeloproliferative neoplasms (MPN), advances in the understanding of CALR-mutant MPN continu...
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Reposted by Kira Gritsman
RUNX1 Research Program @runx1-fpd.org · 09/01/2025
Inflammation plays a key role in RUNX1-FPD pathogenesis. Dr. Anupriya Agarwal & her team at @ohsunews.bsky.social found targeting CD74 signaling, mTOR & JAK1/2 pathways could prevent disease progression. Incredible work by an RRP-EdwardPEvansFdn FIRE grant recipient! www.science.org/doi/10.1126/...
science.org
Targeting the CD74 signaling axis suppresses inflammation and rescues defective hematopoiesis in RUNX1-familial platelet disorder
CD74 signaling drives inflammation and differentiation defects in hematopoietic stem and progenitor cells in RUNX1-familial platelet disorder.
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Reposted by Kira Gritsman
Ann Mullally @mullallylab.bsky.social · 09/12/2024
Stanford #Hematology is recruiting! #ASH24 attendees, pls reach out to me if interested! 👇🏽@stanforddeptmed.bsky.social
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Reposted by Kira Gritsman
Stephen Oh @mpndoc.bsky.social · 06/12/2024
Excited for this workshop this afternoon and grateful to the organizers Christina Glytsou, Panos Ntziachristos, & Dan Starczynowski for the opportunity to speak in the session alongside @gritsmanlab.bsky.social & Marek Mraz! #ASH24 #hemesky @ash-hematology.bsky.social ash.confex.com/ash/2024/web...
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Reposted by Kira Gritsman
Shira G-S, PhD @thehematopoet.bsky.social · 06/12/2024
So sad I am missing #ASH2024 But if you’re there early enough be sure to check out the wonderful @gritsmanlab.bsky.social present exciting updates from my work at the therapy resistance workshop on Friday! 2-5pm in SDCC room 33!
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Kira Gritsman @gritsmanlab.bsky.social · 04/12/2024
Check out our new review by the amazing @alexkschurer.bsky.social and @thehematopoet.bsky.social on chromatin modifiers in AML! Just in time for the first menin inhibitor FDA approval! 🧪🩸
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Johanna Joyce @johannajoyce.bsky.social · 25/11/2024
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/
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Maria Amaya MD PhD @mariaamaya27.bsky.social · 15/11/2024
Big day for our field! 🎉
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Reposted by Kira Gritsman
Lee Grimes Lab @leegrimeslab.bsky.social · 17/11/2024
First manuscript from Linde Miles Lab at CCHMC looking at clonal evolution in NPM1-mut AML at single cell resolution. Check out the pre-print here: www.biorxiv.org/content/10.1...
biorxiv.org
Genotype-immunophenotype relationships in NPM1-mutant AML clonal evolution uncovered by single cell multiomic analysis
Acute myeloid leukemia (AML) is a multi-clonal disease, existing as a milieu of clones with unique but related genotypes as initiating clones acquire subsequent mutations. However, bulk sequencing can...
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