Uli Steidl @steidluli.bsky.social · 04/12/2025Looking forward to the Myeloid Workshop tomorrow! 3PM, W314, @ASH. Excited about a great lineup and looking forward to intense and stimulating workshop-style discussions! And yes, the rubber chicken will be there to keep time and we will follow the traditional "Dan's Rude Rules"... 😀😊🐔 070
Reposted by Uli SteidlDivij Verma @divijverma.bsky.social · 02/12/2025Excited to share a big milestone, the Verma Lab divijvermalab.com is now OPEN @einsteinmededu.bsky.social We study how environmental exposures & inflammation drive stem-cell dysfunction and cancer. Grateful to mentors Amit Verma & @steidluli.bsky.social . We’re #NIH R01-funded lab and #hiring 053
Uli Steidl @steidluli.bsky.social · 05/11/2025👇🐔Friday, Dec 5, 3-7 PM, room: W314🐔👇 Update: The myeloid workshop is back online on the ASH webpage: hematology.org/meetings/ann...hematology.orgScientific Workshops - Hematology.orgScientific Workshops 010
Uli Steidl @steidluli.bsky.social · 05/11/2025👇👇 Mark your calendars! Fri, Dec 5, 3-7pm @ ASH. 🐔🐔 031
Uli Steidl @steidluli.bsky.social · 05/10/2025Thank you! I am deeply honored and grateful to the scientific community at ISEH for receiving this award! All the brilliant, fearless, and hard-working former and current lab members who I have had the privilege to work with are the true stars here! 😊🤩 Thank you all! 🙏 052
Reposted by Uli SteidlElizabeth McKenna @elizsmckenna.bsky.social · 01/10/2025Now online in Cancer Discovery @aacrjournals.bsky.social: Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-Related Patterns and Relies on IL1RAP for Clonal Expansion doi.org/10.1158/2159... 195
Reposted by Uli SteidlMick Milsom @milsommick.bsky.social · 30/09/2025Surprising finding that standard chemo renders AML resistant to subsequent treatment with menin inhibitors. Published in @isehsociety.bsky.social journal Exp. Hem.: www.exphem.org/article/S030...exphem.orgUpfront Menin-inhibitor resistance in multiply pretreated leukemias10% of acute leukemias carry rearrangements of the KMT2A gene (Mixed-Lineage Leukemia-1, MLL-1). More than 80 fusion partners have been identified, and differences in fusion partner have been linked t... 1176
Reposted by Uli SteidlKira Gritsman @gritsmanlab.bsky.social · 28/08/2025Happy to contribute to this exciting project just published in @nature.com led by the amazing Shoichiro Takeishi in a fantastic collaboration with @steidluli.bsky.social - check out this thread 🩸 🧬 062
Uli Steidl @steidluli.bsky.social · 28/08/2025Recruiters watch out! Shoichiro is entering the faculty job market right now... 000
Uli Steidl @steidluli.bsky.social · 28/08/2025We also found that thrombopoietin has a pivotal role in determining total HSC numbers in the body, even in the context of increased niche availability. Our study provides new insights into stem cell number regulation and opens avenues of investigation into various fields. (6/6) 000
Uli Steidl @steidluli.bsky.social · 28/08/2025Moreover, HSC numbers in transplanted wild-type femurs did not exceed physiological levels when HSCs were mobilized from defective endogenous niches to the periphery, indicating that HSC numbers are constrained at the local level as well. (5/6) 100
Uli Steidl @steidluli.bsky.social · 28/08/2025To test this, we developed a femur-transplantation system, enabling us to increase HSC niche cells without adding HSCs. Surprisingly, adding niches did not increase the total HSC numbers in the body, revealing the presence of systemic mechanism(s) that limits HSC numbers. (4/6) 100
Uli Steidl @steidluli.bsky.social · 28/08/2025We and others have previously identified several HSC niche components, including mesenchymal stem cells in the bone marrow. However, their numbers significantly exceed HSC numbers, leading us to hypothesize that other regulatory mechanisms govern HSC numbers. (3/6) 100
Uli Steidl @steidluli.bsky.social · 28/08/2025HSCs play a major role in blood cell production, making the regulation of HSC numbers a central question in stem cell biology. A model from the 1970s suggested that HSC numbers are determined locally by the availability of their bone marrow microenvironments, or niches. (2/6) 100
Uli Steidl @steidluli.bsky.social · 28/08/2025Please check out this thread on our latest paper in @nature.com on HSC pool size regulation. rdcu.be/eCJLe Phenomenal collaboration with @gritsmanlab.bsky.social, and driven by the outstanding Shoichiro Takeishi! @einsteincellbio.bsky.social @einsteinmededu.bsky.social (1/6)rdcu.beHaematopoietic stem cell number is not solely defined by niche availabilityNature - Haematopoietic stem cell numbers are restricted at both systemic and local levels. 282
Reposted by Uli Steidlernstlaboratory.bsky.social @ernstlaboratory.bsky.social · 21/07/2025The Myeloid Workshop is back in ASH! Please contact the organizers if you have an exciting story that will not be out by December they are: Zuzana Tothova , @ernstlaboratory.bsky.social @steidluli.bsky.social @ericpietras.bsky.social @kathrinbernt.bsky.social @gritsmanlab.bsky.social 0198
Reposted by Uli SteidlISEH - International Society for Experimental Hematology @isehsociety.bsky.social · 12/06/2025Continuing our interview spotlight series is the 2025 McCulloch and Till Awardee @steidluli.bsky.social Dr. Steidl discusses his current work, career inspirations and more. Watch part III on www.simplyblood.org 063
Reposted by Uli SteidlNYCTrainKUHR @nyctrainkuhr.bsky.social · 22/05/2025Our trainees had a truly enriching experience at #KUHRTN2025 at Emory, Atlanta! They gained insights into career development, received valuable advice, and enjoyed connecting with field leaders and peers from across the country. bit.ly/3H529IZ @steidluli.bsky.social @gritsmanlab.bsky.social 132
Uli Steidl @steidluli.bsky.social · 07/05/2025Thank you! And proud to be part of this outstanding institute under the leadership of @jaguirreghisolab.bsky.social 120
Uli Steidl @steidluli.bsky.social · 07/05/2025Thank you, Julio! The feelings are absolutely mutual. Grateful for your friendship, input, and support! 010
Uli Steidl @steidluli.bsky.social · 30/04/2025I am incredibly humbled being elected into the AAP. Grateful to all the highly dedicated former and current team members and collaborators who enabled the scientific progress that led to this big honor! Also a huge thank you to my nominator and long-standing role model @jdlicht.bsky.social ! 2150
Reposted by Uli SteidlAmerican Society of Hematology @ash.hematology.org · 14/02/2025📢 Support federal research funding! As the new Administration acts & Congress finalizes FY25 funding, lawmakers need to hear from you. Share your stories of how funding & policies impact #hematology patients & research. Take action! bit.ly/4b2bj43 #Fight4Hematology #HemeSky #BloodSky 02515
Reposted by Uli SteidlKira Gritsman @gritsmanlab.bsky.social · 10/04/2025So excited that our collaboration with the Shechter lab on a new targetable PTM -glutamylation- on NPM1c in AML is now on BioRxiv! Team effort led by @alexkschurer.bsky.social and @humaira2204.bsky.social! 🧪🩸humaira2204.bsky.socialHumaira (@humaira2204.bsky.social)Research Fellow in the Dept. of Biochemistry, Working with Histone Chaperones. @einsteinmed Baking Enthusiast, Book Lover, Webseries Buff 🙃 1152
Uli Steidl @steidluli.bsky.social · 12/04/2025The future of ISEH looks very bright! Congrats to all! 041
Reposted by Uli SteidlISEH - International Society for Experimental Hematology @isehsociety.bsky.social · 21/03/2025Don't miss your chance to submit an abstract to #ISEH2025 🏯! With 20+ short talk slots available, selected presenters may be invited to share their work on stage. Deadline to submit is 12 May. www.iseh.org/2025Abstracts 043
Reposted by Uli SteidlISEH - International Society for Experimental Hematology @isehsociety.bsky.social · 09/04/2025🚨 Students, postdocs, and junior faculty🚨 Don't miss your chance to connect with expert faculty from around the world this hiring season! The NIC is hosting a FREE career fair on 15 April ➡️ www.iseh.org/CareerFair2025 052
Reposted by Uli SteidlKeisuke Ito @keisukeito-lab.bsky.social · 25/03/2025Had a blast co-hosting Dr. Shu-Chi Allison Yeh (@urochester.bsky.social) at Einstein Stem Cell Institute today with @steidluli.bsky.social! The talk on tracking bone marrow niche using intravital imaging was fascinating. Enjoyed wonderful dinner discussions, and so excited about our collaborations! 152
Reposted by Uli SteidlKeisuke Ito @keisukeito-lab.bsky.social · 17/03/2025Thrilled to co-host Dr. Shu-Chi Allison Yeh from Rochester CMSR (@urochester.bsky.social) for the Einstein Stem Cell Institute seminar on intravital tracking and manipulation of the bone marrow niche at 3 PM, Monday, March 24th, with Dr. Steidl (@steidluli.bsky.social)! @einsteinmededu.bsky.social 024
Uli Steidl @steidluli.bsky.social · 13/03/2025I am also thrilled to be in such illustrious company with scientists and friends who I have been inspired by for many years! Congrats to all!! 020
Uli Steidl @steidluli.bsky.social · 13/03/2025I am deeply honored and immensly grateful to the scientific community at ISEH for receiving this award! And a big shoutout and thank you to all the brilliant and hard-working former and current members of my lab who made the progress possible that led to this award! 😊 🙏 Let's keep going!! 5254
Uli Steidl @steidluli.bsky.social · 25/01/2025Congrats, Divij, and all other recipients! Looking forward to following your careers and the exciting and impactful scientific discoveries you will make! @einsteincellbio.bsky.social 040
Reposted by Uli SteidlISEH - International Society for Experimental Hematology @isehsociety.bsky.social · 20/12/2024Save the date for ISEH 2025! View travel details and Annual Scientific Meeting Speakers here: www.iseh.org/page/iseh2025 096
Reposted by Uli SteidlISEH - International Society for Experimental Hematology @isehsociety.bsky.social · 09/01/2025The first Preprint Watch for 2025 is plentiful: 9 preprints focusing on Acute Myeloid Leukemia, but also spatial fate mapping meets barcoding, how cell fate decisions occur in hematopoietic progenitors, and more! Read now➡️ simplyblood.org 0158