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Sophie Lanciano

@sophielanciano.bsky.social

115 followers 118 following 2 posts

Assistant Professor at the University of Montpellier | Institute of Human Genetics | Epigenetics, Genomics & Transposable Elements Former PostDoc at Cristofari Lab

Posts Replies Media

Reposted by Sophie Lanciano

Geoff Faulkner @faulknerlab.bsky.social · 30/07/2026

Our study published today @science.org shows that X-chromosome inactivation (XCI) attracts L1 mutations to the human X chromosome: doi.org/10.1126/scie... With outstanding Perspective from @aurelien-doucet.bsky.social & @retrogenomics.bsky.social: doi.org/10.1126/scie...

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Reposted by Sophie Lanciano

Ivan Zanoni @lozanzi.bsky.social · 12/12/2024

#NotOnlyParasites! 2 Cell papers by @edchuong.bsky.social lab & Amigorena lab demonstrate that transposable elements #TEs can exonize giving rise to functional (often shorter) proteins with distinct functions: eg a decoy short IFNAR2 that inhibits #interferon signaling! www.cell.com/cell/fulltex...

cell.com

Transposable element exonization generates a reservoir of evolving and functional protein isoforms

Transposable element exonization by unannotated splicing events produces stable protein isoforms with acquired functions that are subject to evolutionary selection.

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Sophie Lanciano @sophielanciano.bsky.social · 05/02/2024

I'm so excited to announce that our story on LINE-1 DNA methylation has been published in @CellGenomics 🥳🥳 With @retrogenomics.bsky.social @aurelien-doucet.bsky.social and all other authors. Enjoy the reading! www.cell.com/cell-genomic... See original thread below.

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