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Joanna Smeeton

@smeetonlab.bsky.social
2.4K followers 974 following 30 posts

Assistant Professor @Columbia in NYC. Developmental biologist focused on regeneration research in zebrafish. Rebuilding joint ligaments and cartilage at the Columbia Stem Cell Initiative. All views my own.

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Reposted by Joanna Smeeton
Tessa Montague @tessamontague.bsky.social · 06/06/2026
Do you know an outstanding aquarist? We're hiring a Senior Aquarist to help run our cephalopod facility at Columbia University. Our team maintains a colony of 250+ cuttlefish, develops new husbandry techniques (inc transgenics) & studies cuttlefish camouflage and social behavior. 1/3 [Pls repost!]
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Joanna Smeeton @smeetonlab.bsky.social · 27/03/2026
En route to #ORS2026. Very grateful to the TSA agents for processing us as quickly as possible this morning. 2.5hrs in the security line at LGA Terminal C.
TSA security line at LGA airport at 5am
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Joanna Smeeton @smeetonlab.bsky.social · 21/03/2026
Attended our first MARZ meeting today. A wonderful day of science and community building! 🧪 #zebrafish
Joanna and Everett in front of the Penn logo.Mid Atlantic Regional Zebrafish meeting logo on a conference projector screen.
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Cecilia Moens @cbmoens.bsky.social · 17/02/2026
The new @IZFS News Splash is out! IZFS.org/newssplash/news-splash-issue-21-winter-2026 . Check it out for a SCZI meeting report, Alternatives to Academia (alliance management), Science Spotlight articles, member news and more!
izfs.org
News Splash Issue 21 Winter 2026 | IZFS - International Zebrafish Society
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Gettin' Fishy With It Podcast @gettinfishypod.bsky.social · 12/02/2026
For #BlackHistoryMonth and International Day of Women and Girls in Science, we wanted to highlight a few organizations you should follow and support! We'll link their websites, be sure to check them out!
media.tenor.com
a man in a suit says check this out in yellow letters
ALT: a man in a suit says check this out in yellow letters
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Peter Fabian @fabianlab.bsky.social · 06/02/2026
Thinking about EZM2026 in Vienna? 🐟 Travel grants are now open for students & ECRs. 7–11 July 2026 | Deadline: March 15 Hope to see many of you there! @ezsociety.bsky.social #zebrafish
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Joanna Smeeton @smeetonlab.bsky.social · 05/11/2025
A gorgeous evening here in NYC
An orange sunset over NYC
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Joanna Smeeton @smeetonlab.bsky.social · 31/10/2025
Working with #zebrafish you might expect us all to be from the Water Tribe, but representatives from all nations of the world of #Avatarthelastairbender turned out to represent the Smeeton lab at our Columbia Stem Cell Hallowe'en party this year!
A group of 8 people dressed as characters from the TV show Avatar: the Last Airbender.A group of 8 people dressed as characters from the TV show Avatar: the Last Airbender.
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Joanna Smeeton @smeetonlab.bsky.social · 13/10/2025
Chlorine in the water
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Development @dev-journal.bsky.social · 13/10/2025
Speaking science in a fractured world: making truth land when facts alone cannot A Perspective by @rebeccacalisi.bsky.social, @kaliceaphd.bsky.social, Jamy Peng, @spiraldoc.bsky.social & @rogerslabucd.bsky.social on how to combat scientific misinformation journals.biologists.com/dev/article/...
Picture of Perspective title and authors from article PDF
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NY-CURES @nycures.bsky.social · 02/10/2025
The BIGGEST impact you can have with 1 minute today ⏱️ Add your name to show NY is ready for a statewide biomedical institute. CA’s CIRM & TX’s CPRIT proved it works—billions returned, jobs created, cures accelerated. Let’s do even better for New York. ✍️ www.nycures.org/
nycures.org
New York Cures – NY-CURESNew York Cures Website
NY-CURES is working to advance bold, state-backed investment in biomedical research—on the scale of successful initiatives in California and Texas—to grow New York’s leadership in science, innovation, and health.
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Joanna Smeeton @smeetonlab.bsky.social · 29/09/2025
📣🧪 Read our latest #research on joint regeneration in #zebrafish, published today in @natcomms.nature.com www.nature.com/articles/s41... @columbiauniversity.bsky.social
nature.com
Dynamic cell fate plasticity and tissue reintegration drive functional adult synovial joint regeneration after complete resection - Nature Communications
Joint injury and disease are leading causes of disability, with mammalian joints exhibiting poor regenerative capacity. Here the authors showed that after loss of a whole joint, adult zebrafish regenerate de novo articular cartilage, ligament, and synovium into a complex joint organ.
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Joanna Smeeton @smeetonlab.bsky.social · 24/09/2025
🍾🧪The end of an era! Today we said so long to Dr. Troy Anderson. Troy was the very first person to join me in the Smeeton lab. He just defended his PhD and is off to start his postdoc next month. We will miss you Troy!! #proudPI @troy-anderson.bsky.social #zebrafish
A photo of Joanna Smeeton and Troy Anderson. Joanna is pointing to the PhD celebration champagne cork from Troy's defense that he is holding Troy smiling and holding a box after packing up his desk.
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Orthopaedic Research Society @orssociety.bsky.social · 28/08/2025
Register now for an ORS Tendon Section #WebinarWednesday on Sept 24, 12 PM CST, A Tendon-cy to Heal: Regenerating Tendons & Ligaments in Zebrafish. Hear from Thomas Schilling, Jenna Galloway & Joanna Smeeton on the latest #tendon & ligament regeneration. 🔗 ors.memberclicks.net/ten092425web#/
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Zebrafish Rock! @zebrafishrock.bsky.social · 06/06/2025
Due to their aquatic environment, #zebrafish are perfect for small molecule drug screens. Many drugs have been repurposed for novel treatments such as COX inhibitors in leukemia & glucocorticoids in long QT syndrome. For more, read this Nature review ($): doi.org/10.1038/nrd4... #ZebrafishFunFacts 🧪
Figure taken from MacRae & Peterson (2015): How suitable are zebrafish for discovering human drugs? Although zebrafish enable in vivo studies on a large scale, questions remain about how relevant the findings are for drug discovery. Recent studies have begun to elucidate the degree of conservation between humans and zebrafish, which share 82% of disease-associated targets and a large number of drug metabolism pathways (as illustrated by the mass spectrometry of metabolic by-products). Zebrafish physiology is often well conserved (sometimes more so than rodent physiology); for example, cardiac electrophysiology (illustrative electrocardiogram (ECG) tracings from each organism are shown). Several compounds discovered in zebrafish screens have been shown to exhibit similar effects in rodent models and humans, including eight out of ten compounds tested by our groups. m/z, mass to charge ratio.
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Zebrafish Rock! @zebrafishrock.bsky.social · 01/06/2025
Revascularization of coronary endothelial cells during zebrafish heart regeneration. Credit to @harrisonlab.bsky.social. #ZebrafishZunday 🧪
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Shawn Burgess @burgesslab.bsky.social · 15/05/2025
Some exciting news! NCBI has finished the annotation pipeline for our new #zebrafish reference sequence GRCz12tu: www.ncbi.nlm.nih.gov/refseq/annot... This is a big step up in data depth and quality and should be super helpful going forward.
ncbi.nlm.nih.gov
Danio rerio Annotation ReportTwitterFacebookLinkedInGitHubNCBI Insights BlogTwitterFacebookYoutube
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International Zebrafish Society @izfs.bsky.social · 17/04/2025
We are excited to announce our next issue of #NewsSplash has been published! To keep up with all the latest #zebrafish news, be sure to check it out here: www.izfs.org/newssplash/n...
izfs.org
News Splash Issue 19 Spring 2025 | IZFS - International Zebrafish Society
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Ele Willoughby @minouette.bsky.social · 20/03/2025
Happy birthday to Canadian medical researcher & #biochemist Maud Menten (1879-1960). 🧪🐡👩🏼‍🔬 #histscj Not only was she an author of Michaelis-Menten equation for enzyme kinetics, she invented the azo-dye coupling for alkaline phosphatase, 1st example of enzyme histochemistry, still used in imaging of 🧵
Linocut portrait of biochemist and medical researcher Maud Menten (1879-1960) with the Michalis-Menten equation in blue and a histology image in pinks and purples in the background.
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Joanna Smeeton @smeetonlab.bsky.social · 06/03/2025
Heading back to NYC full of fresh ideas and new questions to explore after a wonderful visit with the fantastic faculty and trainees @cuanschutz.bsky.social Thanks again for the invitation to share our work on craniofacial joint regeneration!
4 smiling research scientists
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International Zebrafish Society @izfs.bsky.social · 10/02/2025
Abstract submissions for the 19th IZFC are now open! Registration to the conference is required to submit an abstract. Register and submit here today! www.izfs.org/education/19...
izfs.org
Abstracts | IZFS
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Science Magazine @science.org · 10/02/2025
Breaking news: 22 states are suing to block NIH’s cutting of indirect costs. See our updated story on the Friday night news and its aftermath. scim.ag/4hTJQ6v
scim.ag
NIH slashes overhead payments for research, sparking outrage and lawsuit
Move to cut indirect cost rate to 15% could cost universities billions of dollars
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Joanna Smeeton @smeetonlab.bsky.social · 08/02/2025
"We need eachother more than ever before" #ORS2025
ORS President at a podium in front of a screen showing the word Community
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Carl T. Bergstrom @carlbergstrom.com · 08/02/2025
1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
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Zebrafish Information Network (ZFIN) @zfinmod.bsky.social · 03/02/2025
ZFIN is now on Bluesky!
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Katie Mack @astrokatie.com · 28/01/2025
I think some people hear “grants” and think that without them, scientists and government workers just have less stuff to play with at work. But grants fund salaries for students, academics, researchers, and people who work in all areas of public service. “Pausing” grants means people don’t eat.
washingtonpost.com
White House pauses all federal grants, sparking confusion
The Trump administration has put a hold on all federal financial grants and loans, affecting tens of billions of dollars in payments.
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Crump Lab @crumplab.bsky.social · 22/01/2025
Nice article in Scientific American about our work on outer ear evolution and a complimentary study from the lab of Maksim Plikus on role of unique lipids in mammalian ear cartilage. www.scientificamerican.com/article/our-...
scientificamerican.com
Our Ears Share a Common Ancestry with Fish Gills
The genes that build the cartilage of fish gills were repurposed to build the cartilage in mammals’ outer ears
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Development @dev-journal.bsky.social · 22/01/2025
Sox10 is required for systemic initiation of bone mineralization Read this #OpenAccess Research Article by Stefani Gjorcheska, Lindsey Barske & co. @cincyresearch.bsky.social : journals.biologists.com/dev/article…
Figure 1 (A) Example images illustrating a major delay in initiation of bone mineralization in sox10 mutants between 3 and 7 dpf revealed by Alizarin Red staining. Some mineralization is present by 5 dpf but never achieves control levels before lethality at 8 dpf.
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Megan Killian @megankillian.bsky.social · 14/01/2025
Are you a trainee in the @orssociety.bsky.social Tendon Section, and are the presenting author on an abstract at this year's meeting? If you are going to be at the annual meeting, sign up to compete in the 3-minute-thesis competition! $$ prizes will be awarded! forms.gle/WneTNbVpuECP...
forms.gle
2025 ORS Tendon Section: 3 Minute Thesis competition
We invite you to apply to give a short presentation (think “elevator pitch” or short TED talk) to share your thesis research/concept to your peers! This contest is designed for you to communicate your...
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Science Magazine @science.org · 15/01/2025
Slow-motion videos reveal tree frogs making some of the most dramatic landings in nature. Learn more: scim.ag/4gTAurn
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Gettin' Fishy With It Podcast @gettinfishypod.bsky.social · 10/01/2025
Season 3 is here! Hear about our thoughts on season 2, and what we look forward to in season 3! From live streams to live panels at massive gaming conventions, 2024 was so incredible! 2025 is already shaping up to be an amazing year for the podcast, so be sure to tune in!
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Joanna Smeeton @smeetonlab.bsky.social · 17/12/2024
📢🧪For your holiday travel reading, check out our new pre-print! Using a new joint resection injury model, we describe an innate regeneration program in adult #zebrafish that reestablishes all major synovial joint cell types, including lubricated articular cartilage. www.biorxiv.org/content/10.1...
biorxiv.org
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Ondine Cleaver @ondinecleaver.bsky.social · 26/11/2024
My WISMAC co-chair and partner in crime Kimberly Kho sent me this. It reminded her of Sharon Reimold who recently passed. We celebrate Sharon’s vision and leadership. Also a reminder that in science, it’s important we celebrate each other’s victories and awesomeness now and openly. Be generous.
Quote about not admiring quietly. Let’s tell each other, and celebrate each other’s successes.
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Peter Fabian @fabianlab.bsky.social · 21/11/2024
Check out how #neuralcrest cells 🔬 migrate (animal= #zebrafish, white cells=sox10+, start=10 somites stage, anterior=top)
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Sarah Rice @grainofscience.bsky.social · 14/11/2024
To help connect researchers in the #osteoarthritis #musculoskeletal and #ortho fields, @kelseyhcollins.bsky.social and I have started an MSK Research Starter Pack. It’s early days, but please me know if you want to be added! go.bsky.app/DJVukXR
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Zebrafish Rock! @zebrafishrock.bsky.social · 19/11/2024
The latest recording of the Bristol Zebrafish Zoom Talks (#BZZT) is now available to watch on our Slack Pro tankspace. The fishy talk from @smeetonlab.bsky.social is titled, ““Decoding progenitor activation in new models of joint cartilage and ligament regeneration in zebrafish.” Go watch! 😊
Alcian blue and alizarin red staining of the jaw of an adult zebrafish. Mouth to the left.
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Peter Fabian @fabianlab.bsky.social · 17/11/2024
Back in Crump Lab we did some nice imaging with @smeetonlab.bsky.social #zebrafish 😍
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Zebrafish Rock! @zebrafishrock.bsky.social · 11/11/2024
We joined the trend of Starter Packs! Check out our (non-exhaustive) list of Group Leaders & Senior Scientists that work with our favorite fishes! #zebrafish go.bsky.app/2cHYybY 🧪
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Çağrı Çevrim @cagricevrim.bsky.social · 11/11/2024
I love how the scientific community here is growing. Here, I started a list of regenerative biologist: go.bsky.app/MGXL9Ra
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Crystal Rogers, PhD @rogerslabucd.bsky.social · 12/02/2024
Please check out our recent perspective paper, “Pluripotency of a founding field: rebranding developmental biology.” Huge thanks to the 50 scientists who came to California to discuss the future of #DevBio and contributed to the paper, and thanks to NSF for $! journals.biologists.com/dev/article/...
journals.biologists.com
Pluripotency of a founding field: rebranding developmental biology
ABSTRACT. The field of developmental biology has declined in prominence in recent decades, with off-shoots from the field becoming more fashionable and highly funded. This has created inequity in disc...
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Josh Barber @joshbarbershop.bsky.social · 19/01/2024
Lovely piece on the fish scientists I’m lucky to support! They are all rock stars! @smeetonlab.bsky.social www.cuimc.columbia.edu/news/fishing...
cuimc.columbia.edu
Fishing for Insights into Human Disease
In this photo essay, Columbia researchers explain how they are using zebrafish and killifish to gain insights into human health and disease.
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Joanna Smeeton @smeetonlab.bsky.social · 21/12/2023
I'm so thankful for an excellent 2023 with this talented crew. I mean, c'mon, look at our lab's festive door with their hand-made avatars☃️🐧🎁🏔️. Happy Holidays!
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Joanna Smeeton @smeetonlab.bsky.social · 19/12/2023
🎉 Today we said farewell to our lab's first undergraduate researcher, Eric Mao. Eric has been working closely with Troy over the past three years and has been an absolutely stellar lab member. He is med school bound next year. Congrats Eric! We will miss you! 🎉
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Joanna Smeeton @smeetonlab.bsky.social · 31/10/2023
🎃 Well, this year my lab finally got tired of working with zebrafish. But, we didnt just want to start working with rodents, we thought we'd try being rodents! Happy Halloween from these lab rats! 🎃
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Zebrafish Rock! @zebrafishrock.bsky.social · 31/10/2023
Happy Halloween to the foolish and freaky fry out there! Credit artwork to the talented Priyanka Oberoi 🎃🧌
Zebrafish Regenerastein. Available merchandise at redbubble.com. Credit to Priyanka Oberoi
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Laura Lopez @ohdearz.bsky.social · 30/10/2023
Reminder that the Big Ten Academic Alliance Fee Waiver program gives waivers for 15 schools' PhD programs (including OSU astro and OSU physics) for US citizen students w/ 3.0+ GPAs and diverse backgrounds! Easy form to complete due by Nov 15. btaa.org/resources-fo...
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Joanna Smeeton @smeetonlab.bsky.social · 19/09/2023
🧪 📣 Tendon/ligament/regeneration/zebrafish enthusiasts! I'm pleased to announce that Troy and Julia's paper on dedifferentiation and ECM remodeling in ligament regeneration is out today in npj Regenerative Medicine. Look ma, no scars! www.nature.com/articles/s41... 🥳 So proud of the whole team! 🥳
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