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Sibelle Vilaça

@sibellevilaca.bsky.social
583 followers 356 following 40 posts

Population genetics of endangered species 🇧🇷 I like #seaturtle hybrids.

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Reposted by Sibelle Vilaça
Kelly Zamudio @kzutaustin.bsky.social · 30/09/2026
Olha ai gente! 🇧🇷🇧🇷🇧🇷 Travel funds and registration to attend #Evol2027!
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Cedric Feschotte @cedricfeschotte.bsky.social · 24/09/2026
Thrilled to see this published today! Truly special because we made the initial discovery >15 yrs ago! We found two copies of a human gene called BC200 embedded in a human poxvirus. BC200 blurs the line between gene & transposon—both functional & mutagenic! www.science.org/doi/10.1126/... 🧵1/n
science.org
Escape of the BC200 gene to a human poxvirus reveals its persistent transposition in primates
Transposable elements mobilize within and occasionally between genomes, including from host to virus. We identified two insertions of the human BC200 noncoding RNA gene in the poxvirus molluscum conta...
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BK. Titanji @boghuma.bsky.social · 24/09/2026
"I’m saying that I would personally mouth-pipette a solution of pure chloroform right now, today, in front of God and the NIH Director and the entire Office of Research Safety, if it meant a young scientist in my department could get a payline above 20%." substack.com/home/post/p-...
substack.com
Opinion: I Miss When The NIH Payline Was 40% And We All Mouth-Pipetted Phenol
By Dr. Douglas R. Waverly, Professor Emeritus of Biochemistry, Yale University
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Sonja Vernes @sonjavernes.bsky.social · 23/09/2026
🦇 Bat1K's biggest paper yet is out. Largest bat genome + fossil study ever: 103 genomes, 44 fossils, 137 researchers. We rewrote the bat family tree! Bats likely originated in Europe ~65 million years ago, not Asia, Africa or Americas. @bat1kgenomes.bsky.social doi.org/10.1038/s41586-026-11007-3
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Ricardo J Pereira @biodiversitysmns.bsky.social · 22/09/2026
Island species 🏝️ frequently experience founder events and population bottlenecks 🧬 and are often subject to disturbances that further reduce population sizes. Despite these challenges, some island lineages persist for millennia 🕰️ —the paradox of persistence. Here’s what we learned about it:
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Joe Hanly @hanliconius.bsky.social · 22/09/2026
I hate to do this with real data, but this is a persistent data vis issue in chromosome synteny riparian plots that we Need to get better at. Left, a synteny plot published today. Right, a rearranged version with exactly the same gross arrangement but with reordered chromosomes:
chromosome synteny riparian plot in which every chromosome has crossing lineschromosome synteny plot in which no chromosomes have crossing lines. The underlying structure is identical.
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Nature @nature.com · 14/09/2026
Wealthy philanthropies in Brazil are starting to put their money into science — a trend that could help to protect research funding if voters in next month’s elections choose a president who doesn’t prioritize the sciences. go.nature.com/4A7Tz3n
go.nature.com
Donor-funded science is rising in Brazil ― upending a long tradition
Philanthropists are stepping up support for research in a country where scientists have relied on the government alone for funding.
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Nature @nature.com · 08/09/2026
AI model AlphaGenome forecasts the consequences of altering every single DNA letter in the human genome go.nature.com/4xQ7ZDK
go.nature.com
DeepMind’s new genome ‘atlas’ charts effects of all 9 billion human gene mutations
AI model AlphaGenome forecasts the consequences of altering every single DNA letter in the human genome.
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Joachim Mergeay @jmergeay.bsky.social · 03/09/2026
We calculated the effective size of the Scandinavian wolf population every year since its founding from the entire pedigree. Why? Because we could. But also because this population is vulnerable, and policy keeps pushing for lower and lower conservation targets 1/ #consgen
nature.com
The effective size of the Scandinavian wolf population is too small for both short- and long-term conservation - Heredity
Heredity - The effective size of the Scandinavian wolf population is too small for both short- and long-term conservation
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Laura Bertola @lauradbertola.bsky.social · 03/09/2026
Runs of Homozygosity Predict Inbreeding Depression Across Taxa: A Systematic Review and Meta-Analysis onlinelibrary.wiley.com/doi/epdf/10....
onlinelibrary.wiley.com
Runs of Homozygosity Predict Inbreeding Depression Across Taxa: A Systematic Review and Meta‐Analysis
Reader environment loaded
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Max Telford @maxjtelford.bsky.social · 02/09/2026
Important paper by @kaplipa.bsky.social and colleagues. Advocating for the importance of Natural History museum collections in genomics. www.nature.com/articles/s41...
nature.com
Species-dense genomics through natural history collections - Nature Reviews Genetics
Large-scale genome initiatives are transforming biodiversity genomics, but genomes remain taxonomically sparse and difficult to compare across species. Kapli and colleagues argue that natural history ...
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alex ioannidis @alexgioannidis.bsky.social · 03/09/2026
ARGformer is out in Bioinformatics! doi.org/10.1093/bioi... Just as PCA reduces dimensionality from genotypes, ARGformer can do this now for ARGs...yielding a representation that comes directly from inferred genealogical topologies & at a haplotype level across each individual genome.
doi.org
ARGformer: learning on ancestral recombination graphs with transformers
AbstractMotivation. Recent advances in inference of the ancestral recombination graph (ARG), which describes how segments of chromosomes trace back through
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Ina Satokangas @inasatok.bsky.social · 01/09/2026
A cool bunch of new speciation papers out recently in Molecular Ecology, looking at divergence, hybridisation, recombination, genome architecture, and so on! Genomics of Speciation special issue: onlinelibrary.wiley.com/doi/toc/10.1... #speciation #divergence #hybridisation #recombination #genomics
onlinelibrary.wiley.com
Special Issue: Genomics of Speciation: Molecular Ecology
Molecular Ecology is an international journal for research using molecular genetic techniques to address questions in ecology, evolution, behavior and conservation.
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Mike Keesey @tmkeesey.bsky.social · 30/08/2026
We are getting VERY close 13,000 silhouettes! www.phylopic.org/images
phylopic.org
All Silhouette Images on PhyloPic
Browse all the free silhouette images in PhyloPic.
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7th European Conservation Genetics Meeting @consgenmeeting2026.bsky.social · 18/08/2026
‼️Attention, attention! The #ConsGenMeeting2026 Abstract Booklet is officially live! View the selected abstracts here and be inspired: doi.org/10.5281/zeno... #ConservationGenetics #Biodiversity #Conservation #Genetics #Abstracts #AntwerpZoo
doi.org
7th European Conservation Genetics Meeting 2026: Abstract Booklet
7th European Conservation Genetics Meeting 2026: Abstract Booklet This booklet contains the full collection of abstracts for the 7th Conservation Genetics Meeting 2026. It provides a complete overview...
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Gernot Segelbacher 🪶 🧬 @gsegelbacher.bsky.social · 25/08/2026
#CGSG working intensively in Antwerp on the strategy for the coming quadrennium. Thanks everyone for such a inspiring and creative atmosphere! Excellent work done! @cgsg.bsky.social #consgen
group photo of group of people in front of stairs facing the sunshine
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Methods in Ecology and Evolution @methodsinecoevol.bsky.social · 25/08/2026
@animalecology.bsky.social @jappliedecology.bsky.social
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EcoEvoRxiv @ecoevorxiv.bsky.social · 25/08/2026
'Overcoming limitations in selection guidelines for state-of-nature metrics in corporate assessments' doi.org/10.32942/X2V...
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Molecular Biology and Evolution @molbioevol.bsky.social · 24/08/2026
Pavinato & Hey apply a new method to estimate the population selection coefficient for all 134 ordered pairs of synonymous codon changes, providing a direct population-level view of how subtle genetic changes shape molecular evolution. 🔗 academic.oup.com/mbe/article/... #societyjournal #molbio
academic.oup.com
Estimating the evolutionary fitness of specific synonymous codon changes
Abstract. Synonymous mutations do not alter proteins but undergo natural selection in many species. For Drosophila melanogaster, reports on selection stren
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Sibelle Vilaça @sibellevilaca.bsky.social · 21/08/2026
We have a new paper! Here we argue that the Global South needs to play a central role in biodiversity genomics, and not be relegated to sample providers. We also propose a pathway forward. #genomics #consgen www.frontiersin.org/journals/sci...
frontiersin.org
Frontiers | Sequencing life on Earth: why the Global South must be central
The biodiversity crisis is accelerating, with recent IUCN Red List confirming multiple recent species extinctions (IUCN, 2025). Of the 17 megadiverse countri...
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Darrin T. Schultz @dts.bsky.social · 19/08/2026
Our new paper in Science Advances asks how animals' genomes have changed since their origin from a common ancestor over 600 million years ago, and what patterns in their DNA have arisen in the churn of speciation and extinction. www.science.org/doi/10.1126/...
Five-panel diagram explaining fusion-with-mixing in chromosome evolution. Red and blue represent two different ancestral chromosomes throughout.

A, Fusion-with-mixing: a red chromosome and a blue chromosome fuse into one half-red, half-blue bar. Down the page, successive rows show inversions, drawn as X-shaped crossings between rows, progressively interleaving the two colors until the bottom bar is finely striped. A widening gray wedge labeled Entropy runs alongside an arrow marked Time plus evolution, pointing down.

B, Independent regulation: two separate chromosomes, one red and one blue. In each, a regulatory element, drawn as an oval, acts by an arrow on a gene within its own chromosome only.

C, FWM and novel regulation: on a fused, mixed chromosome, a red gene and a blue gene now sit next to each other across an inversion breakpoint. Red and blue arrows show regulatory elements reaching across it to act on the other chromosome's gene.

D, Regulatory entanglement: an extensively mixed chromosome, finely striped. Below it, a row of alternating red and blue genes is linked by a dense web of crossing curved arrows, so many overlapping regulatory connections that unmixing the chromosome would break them.

E, Emergence of entangled loci: a five-species phylogeny. A red and a blue chromosome fuse at an ancestral node, and helical icons on later branches mark continued mixing. Colored boxes mark four new red-blue regulatory interactions arising after inversions. Species A keeps its two chromosomes separate. In species B through E, the two earliest interactions, cyan boxes 1 and 2, are present in every descendant lineage, while later ones, yellow 3 and magenta 4, appear in fewer.
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Mark Phillips @maphillips.bsky.social · 30/07/2026
Recent work from the lab. Even after hundreds of generations of intense directional selection at relatively small Ne, substantial genetic variation persists, and can be rapidly redeployed when the direction of selection reverses. Results are suggestive of balancing selection. doi.org/10.1093/molb...
doi.org
Beyond Fixation: Persistent Genetic Variation Under Intense Selection
Abstract. Understanding how and why genetic variation is maintained under sustained selection remains a central question in evolutionary genetics. Experime
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Gracie12 📎 @gracienlucy.bsky.social · 18/08/2026
Everything is connected .
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Evolution Letters @evolletters.bsky.social · 10/08/2026
Big evolutionary events can fool phylogenetic analyses. A new approach combines phylogenetic regression with eigenvectors to reduce false positives and better account for the history written in genomes. doi.org/10.1093/evle...
doi.org
Characterizing and mitigating confounding by unreplicated evolutionary events in phylogenetic regression
Abstract. When researchers want to test for a direct effect of one attribute on another using interspecific data, they need to account for the confounding
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Megan Dennis @mydennis.bsky.social · 18/08/2026
Our vole preprint is officially published in Cell Genomics @cellpress.bsky.social as part of the T2T special issue! www.cell.com/cell-genomic... Lead author @mabuelanin.bsky.social also built this amazing website that we hope will be a useful resource to the vole community: voles.dennislab.org 🐭
cell.com
Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding
Abuelanin et al. combine PacBio HiFi with low-coverage CiFi proximity-ligation reads in a single library and sequencing run to generate contiguous, near-telomere-to-telomere, accurately phased diploid...
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Sibelle Vilaça @sibellevilaca.bsky.social · 17/08/2026
www.science.org/doi/10.1126/...
science.org
The bridge between science and policy: How IPBES redefined global conservation policy and its path to societal impact
Global policy around climate and nature goals has evolved considerably over the last decade. Today, countries recognize that climate and biodiversity crises are profoundly interconnected, and that one...
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bioRxiv Genomics @biorxiv-genomic.bsky.social · 15/08/2026
The relationship of genetic diversity and inbreeding to extinction risk across over 500 vertebrate diploid genomes www.biorxiv.org/content/10.64898/20…
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Nature @nature.com · 13/08/2026
Different tropical tree species can vary in their ability to withstand drought — and so too, it seems, can distinct populations of the same tree species go.nature.com/4qhiRY3
go.nature.com
Intraspecific variation in tropical trees can drive resistance to drought
Different tropical tree species can vary in their ability to withstand drought — and so too, it seems, can distinct populations of the same tree species.
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Stephan Schiffels @stschiff.bsky.social · 12/08/2026
If you are interested in learning computational population genetics and ancient genomics, I have curated my list of workshops and online tutorials (and will continue to do so) indicating suitability for self-learners and status. You find the list [here](www.stephanschiffels.de/resources.html).
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Jente Ottenburghs | Avian Hybrids @jenteo.bsky.social · 11/08/2026
Genetics and genomics of hybridization | Nature Reviews Genetics www.nature.com/articles/s41... Amazing review! 🤩
nature.com
Genetics and genomics of hybridization - Nature Reviews Genetics
Hybridization, the exchange of genes between divergent lineages, is now recognized as widespread across eukaryotes and essential to understanding genome evolution. In this Review, Schumer and Rieseber...
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Current Biology @currentbiology.bsky.social · 06/08/2026
NEW in CB: paleogenomics reveals sex biases in mammoth remains. Males are overrepresented in natural bone deposits, perhaps because they are more risk-taking, while females dominate human-made bone heaps. www.cell.com/current-biol...
cell.com
Paleogenomic sex inference of mammoth remains sheds light on the anthropogenic nature of bone accumulations
Moots et al. use ancient DNA to compare woolly mammoth sex ratios from anthropogenic bone accumulations and natural depositional contexts. The results show that accumulations are female-biased, which ...
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bioRxiv Genomics @biorxiv-genomic.bsky.social · 07/08/2026
A chromosome-level genome of the franciscana dolphin, Pontoporia blainvillei www.biorxiv.org/content/10.64898/20…
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Current Biology @currentbiology.bsky.social · 07/08/2026
out in Current Beefology💪👇 www.cell.com/current-biol...
cell.com
Increased signaling of the Neanderthal growth hormone receptor
Neanderthals had a robust build, but the genetic basis remains unclear. Kanis et al. show that a Neanderthal growth hormone receptor variant increases cellular growth signaling and is inherited by som...
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 02/08/2026
Can I just include this in paper reviews every time someone ignores invariant sites and calculates π incorrectly?
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Prosanta Chakrabarty @prosanta.bsky.social · 29/07/2026
From collections to conservation: the indispensable role of natural history museums The IUCN Species Survival Commission has published a Position Statement on the vital role of biological collections in biodiversity conservation iucn.org/news/202607/...
iucn.org
From collections to conservation: the indispensable role of natural history museums
The IUCN Species Survival Commission has published a Position Statement on the vital role of biological collections in biodiversity conservation: a formal acknowledgement that natural history museums,...
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 29/07/2026
From the abstract: “promoting a woman to Associate Professor increases female faculty by 1.5 members after 15 years, leads to six additional female PhD graduates over the following decade, and raises the number who subsequently remain in academia and reach tenured positions”
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Trends in Ecology & Evolution @cp-trendsecolevo.bsky.social · 21/07/2026
Online now: Genomic metrics should inform formal conservation threat assessments
dlvr.it
Genomic metrics should inform formal conservation threat assessments
Whole-genome resequencing data, associated metrics, and their trends over time can be used to inform extinction threat rankings rendered by conservation agencies around the world. Surveys of individual genome sequences can critically address risks to population sustainability by means of key metrics such as heterozygosity. Genomic metrics have yet-unrealized potential to help authorities determine how a given population or species of conservation concern should be formally categorized (e.g., ‘listed’ or ‘delisted’) with respect to discrete threat categories. To stimulate productive discourse, we provide a general heuristic framework for how genomic metrics could be used to refine conservation threat assessments (e.g., to help determine whether species should be listed or not).
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Trevor Krabbenhoft @fishgenomes.bsky.social · 24/07/2026
This preprint is now published - www.science.org/doi/10.1126/...
science.org
Genomic structural variation rescues a classic biological invader from a population bottleneck
Genomic structural variants rescue a textbook biological invader from a population bottleneck and inbreeding.
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Royal Society Publishing @royalsocietypublishing.org · 24/07/2026
Looking to build your editorial experience? Join the #ProcB Preprint Editorial Team and help showcase cutting-edge biological research. Develop your publishing expertise, expand your professional network and stay at the forefront of new discoveries. Apply by 1 September 2026 #ECR
royalsocietypublishing.org
Proceedings of the Royal Society B Preprint Editorial Team | Proceedings B | The Royal Society
Proceedings of the Royal Society B Preprint Editorial Team | Proceedings B | The Royal Society Proceedings of the Royal Society B Preprint Editorial Team Our team’s primary mission is to look through…
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Hernán E. Morales @hernmoral.bsky.social · 01/07/2026
Just in time for #SMBE2026, our new preprint is out: using 130 genomes spanning ~200 years, fitness data and simulations, we show that conservation rescued the Mauritius kestrel from extinction, but not from genomic erosion. 🧵 www.biorxiv.org/content/10.6... #popgen #consgen #conservation
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Earth BioGenome Project 🌍 @ebpgenome.bsky.social · 14/07/2026
❄️🧬 Can we generate high-quality reference genomes without the cold chain? A new study suggests the answer is yes. DNA preserved at room temperature for up to one week produced chromosome-scale reference genomes. 📖 tinyurl.com/3zwtj9ka #Genomes @gigascience.bsky.social @sangerinstitute.bsky.social
Close-up photograph of a mosquito perched on a green blade of grass against a dark background. White text at the top reads, "Breaking the Cold Chain." Additional text states, "Room-temperature preservation enables chromosome-scale reference genomes." "GigaScience 2026" appears in the lower-right corner.Three researchers collect biological samples in a forest. One researcher kneels while holding a collection tube beside an insulated cooler, and two others stand nearby preparing samples. A large arrow points to the cooler. Text explains that high-quality reference genomes traditionally require specimens to remain frozen from collection through DNA extraction, highlighting the challenge of maintaining the cold chain during fieldwork.
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Peiwei Chen @peiwei-chen.bsky.social · 17/07/2026
How do transposons jump when they’re released from host control? I babysat two chromosomes for 2 years, making sure they are ok without most piRNAs. Here’s what we found & excited to share my 1st postdoc paper: “piRNA loss unleashes episodic transposition bursts” www.biorxiv.org/content/10.6...
biorxiv.org
piRNA loss unleashes episodic transposition bursts
In Metazoa, transposon expression is suppressed by the piRNA pathway, and disruption of this pathway leads to rampant transposon expression. However, it remains unclear whether increased transposon ex...
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 17/07/2026
Genomic quantification of inbreeding depression in wild vertebrate populations www.biorxiv.org/content/10.64898/20…
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Earth BioGenome Project 🌍 @ebpgenome.bsky.social · 09/07/2026
🐦 Why are bird genomes so difficult to assemble? Birds have dozens of tiny, gene-rich microchromosomes that are frequently fragmented, misplaced, or missing from genome assemblies despite containing important genetic information. 📖 Read the publication: lnkd.in/gar-GrKZ #BirdGenomics #Biodiversity
A promotional graphic on a black background featuring a collage of more than 30 brightly colored bird species from around the world, including birds-of-paradise, toucans, parrots, hummingbirds, flamingos, cranes, owls, kingfishers, waterfowl, raptors, and songbirds. The birds are arranged around the centered text, "MicroFinder Is Now Available," with "MicroFinder" in gold and "Is Now Available" in white. The image highlights the diversity of avian species and announces the release of the MicroFinder computational tool for improving bird genome assemblies.
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GGBN @ggbnoutreach.bsky.social · 08/07/2026
Kew Royal Botanic Gardens is seeking a lab research assistant for the Fungarium Sequencing Project! If you have experience in genomics and museomics techniques, proficiency in statistics and knowledge of UK Health and Safety regulations, then apply before July 26 info careers.kew.org/vacancy/labo...
careers.kew.org
Laboratory Research Assistant - Careers | Kew Gardens
The Labs Research Assistant will deliver RBG Kew’s mission by providing R&D support in the molecular lab as part of a major programme to sequence 20,000 fungi and lichen specimens held by RBG Kew’s fu...
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Debbie Leigh @debbiemleigh.bsky.social · 17/06/2026
Come work with me unlocking the secrets of island genetic diversity patterns! And exploring how the severely elevated genetic erosion we have previously shown on island systems might impact communities. #postdoc #job #germany senckenberg.softgarden.io/job/65352091...
senckenberg.softgarden.io
Postdoctoral Researcher in Macrogenetics (f/m/d) at Senckenberg Gesellschaft für Naturforschung
We're looking for: Postdoctoral Researcher in Macrogenetics (f/m/d) (Full or Part Time) • Frankfurt am Main, Deutschland
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Vertebrate Genomes Project @vertebrategenomes.bsky.social · 06/07/2026
🚨 MANUSCRIPT ALERT 🚨 The VGP Phase I manuscript pre-print is now live on bioRxiv! 🧬 doi.org/10.64898/202... Over 8 years, the VGP generated reference genomes for more than 800 vertebrate species, spanning ~95% of vertebrate orders and delivering some of the highest-quality genomes ever produced.
A graphic announcing the release of the Vertebrate Genomes Project Phase 1 manuscript on bioRxiv with drawings of various vertebrate creatures.The title and author list of the VGP manuscript, "The Vertebrate Genomes Project Phase I: A global reference genome resource"A QR code linking to the pre-print of the VGP manuscript
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GGBN @ggbnoutreach.bsky.social · 05/07/2026
A bioinformatician position is open at Naturalis in the Netherlands! You'll build the high-throughput sequencing and AI pipelines that make species monitoring accessible to researchers, industry, policy and citizens. More info: www.linkedin.com/jobs/view/44...
linkedin.com
Naturalis Biodiversity Center hiring Bioinformatician in Leiden, South Holland, Netherlands | LinkedIn
Posted 1:59:04 PM. Can a teaspoon of soil reveal the species living around it? At Naturalis in Leiden, we turn…See this and similar jobs on LinkedIn.
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Katie Abson @katieabson.bsky.social · 30/06/2026
Our paper is out! 📣 we find that molecular measures of genetic variation do not predict heritable genetic variation across species - important implications for the application of genomic data for conservation! www.pnas.org/doi/10.1073/...
pnas.org
Nucleotide diversity is a poor predictor of short-term adaptive potential | PNAS
The capacity to adapt is essential for a population to avoid extinction in a changing world and is recognized as a global conservation priority. Ad...
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Laura Bertola @lauradbertola.bsky.social · 30/06/2026
The Conservation Genetics Working Group is presenting the 2026 SCB Conservation Genetics Travel Awards ‼️ The primary aim is supporting Global Participation in Conservation Genetics. Check out the details & criteria & apply below. Application deadline: Aug 1, 2026 11:59 PM GMT+0
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