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Mark Phillips

@maphillips.bsky.social
1.4K followers 949 following 10 posts

Assistant Professor at Oregon State University. Evolutionary biologist interested in the genetics of adaptation and complex trait variation. phillipslabosu.com

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Reposted by Mark Phillips
David L Hubert @drhubert.bsky.social · 17/09/2026
Our new paper just came out in G3! It’s a methods-focused study exploring how sampling choices can affect reproducibility in metabolomics research.
doi.org
Signal, noise, and sampling: how pool size and replication shape metabolomic inference
Abstract. Metabolomics provides direct insight into physiological state, but for small organisms such as Drosophila melanogaster, it typically requires poo
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Reposted by Mark Phillips
Aide Macias-Muñoz @aidemm.bsky.social · 16/09/2026
Very happy & proud to share that this paper, led by graduate student Ayanna Mays (first grad student led paper of the lab) is now published 🎉 🧪 #TEsky link.springer.com/article/10.1...
link.springer.com
Comparative analysis of transposable elements in jellyfish and hydroid species (Cnidaria: Medusozoa) - BMC Genomics
Background Transposable elements (TEs) are repetitive genetic elements that can jump to new loci causing genome expansions, structural rearrangements, and can, ultimately, propel the evolution of geno...
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Reposted by Mark Phillips
Graham Coop @gcbias.bsky.social · 10/09/2026
I’m looking to hire an NIH funded postdoc to join our lab here at Davis (please RT). Ongoing areas of interest include: 1) polygenic signals of selection from time series, ARGs, GWAS, etc 2) The interpretation of GWAS, polygenic scores, & sources of confounding
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Mark Phillips @maphillips.bsky.social · 07/09/2026
Recent work from lab member @drhubert.bsky.social on the effects of pool size and replication on statistical inference in fruit fly metabolomic studies. academic.oup.com/g3journal/ad...
academic.oup.com
Signal, noise, and sampling: How pool size and replication shape metabolomic inference
Abstract. Metabolomics provides direct insight into physiological state, but for small organisms such as Drosophila melanogaster, it typically requires poo
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Reposted by Mark Phillips
Aide Macias-Muñoz @aidemm.bsky.social · 04/09/2026
Very happy to share that my lab has been awarded an NIH MIRA! And we will soon be hiring a postdoc to do evodevo + functional genomics 🧬 🧪 news.ucsc.edu/2026/09/jell...
news.ucsc.edu
Understanding how jellyfish eyes first form and regenerate to reveal paths for new human therapies
National Institutes of Health awards just over $2 million to UC Santa Cruz evolutionary biologist Aide Macias-Muñoz for a five-year study of the genetic mechanisms that lead to complex traits like eye...
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Reposted by Mark Phillips
Evgeny Kvon @evgenykvon.bsky.social · 24/08/2026
The newly established Department of Systems Biology (systems.bio.uci.edu) @UCIrvine is hiring a tenure-track Assistant Professor in Systems Biology. Great science, incredible faculty support, and beautiful, sunny SoCal weather! ☀️🌴 Details: recruit.ap.uci.edu/JPF10377. Please share.
recruit.ap.uci.edu
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Reposted by Mark Phillips
Molecular Biology and Evolution @molbioevol.bsky.social · 20/08/2026
@krarnold92.bsky.social @maphillips.bsky.social et al. show that substantial genetic variation can persist under intense directional selection and be redeployed when selection reverses, consistent with widespread balancing selection. 🔗 academic.oup.com/mbe/article/... #societyjournal
academic.oup.com
Beyond fixation: persistent genetic variation under intense selection
Abstract. Understanding how and why genetic variation is maintained under sustained selection remains a central question in evolutionary genetics. Experime
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Reposted by Mark Phillips
Mahul Chakraborty @mahulchak.bsky.social · 07/08/2026
More broadly, the study illustrates how long-read sequencing and pangenome approaches can reveal functionally important variants that are missed by traditional reference-based analyses. The paper is now out in @genomeresearch.bsky.social genome.cshlp.org/content/36/7...
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Reposted by Mark Phillips
Aide Macias-Muñoz @aidemm.bsky.social · 12/08/2026
Excited to share this publication where I explored the expression of TEs during Hydra head regeneration #TEsky link.springer.com/article/10.1...
link.springer.com
Dynamic transposable element expression during Hydra head regeneration - Mobile DNA
Transposable elements (TEs) contribute to genome expansions, gene duplications, and the evolution of gene regulatory networks. Recent work has highlighted the role of TE domestication in contributing ...
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Mark Phillips @maphillips.bsky.social · 30/07/2026
Recent work from the lab. Even after hundreds of generations of intense directional selection at relatively small Ne, substantial genetic variation persists, and can be rapidly redeployed when the direction of selection reverses. Results are suggestive of balancing selection. doi.org/10.1093/molb...
doi.org
Beyond Fixation: Persistent Genetic Variation Under Intense Selection
Abstract. Understanding how and why genetic variation is maintained under sustained selection remains a central question in evolutionary genetics. Experime
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Mark Phillips @maphillips.bsky.social · 15/07/2026
Oregon State University's Department of Integrative Biology is currently hiring up to three tenure-track faculty members, with an emphasis on organismal biology. Note: Previous links are no longer active due to a change in our hiring system. oregonstate.wd501.myworkdayjobs.com/OSU_Careers_...
oregonstate.wd501.myworkdayjobs.com
Assistant Professor
Department: Special Instructions to Applicants: To ensure full consideration, applications must be received by 10/1/26. Applications will continue to be accepted after the full consideration date, unt...
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Mark Phillips @maphillips.bsky.social · 26/05/2026
Recent review I contributed to with colleagues in wood science and engineering on maintaining heartwood quality in plantation-grown timber species. We explore how growth-defense tradeoffs may shape durability, color, and extractive production in trees. doi.org/10.1007/s407...
doi.org
Heartwood Durability: The Quest for Natural Decay Resistance in a Changing Resource - Current Forestry Reports
Purpose of Review Fast-growing plantation resources will increasingly be relied upon to meet global demand for renewable timber products. Concerns exist regarding the quality of wood from plantations and second-growth forests; however, the heartwood quality of timber sourced from plantations and grown for its distinctive color and durability has received little attention. We examine the current status of selected species (in terms of research and development related to heartwood quality) known for their valuable heartwood and explore options that might maintain or improve heartwood quality of plantation grown trees. Findings Plantation grown trees of all species examined had heartwood inferior to that sourced from natural forests. Management of plantation forests to maximize growth can unintentionally promote one process (growth) over other processes (heartwood formation) that may be detrimental to the management objectives related to heartwood durability and color. Heartwood characteristics can be targeted for improvement via breeding or by clonal forestry. Silvicultural interventions to induce a stress response may also improve heartwood quality. Summary Failure to produce quality heartwood has manifold implications, both for plantation growers who may be unable to sell their products for the highest price, and retailers whose reputations depend on meeting customer performance expectations. Management decisions that deliberately cause a stress response (as opposed to maximizing growth) should be considered if plantations are being established using species valued for their heartwood properties. Advanced genetics and silvicultural strategies to promote heartwood formation on suitable sites are necessary to ensure that high value heartwood can be obtained from plantation forests.
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Reposted by Mark Phillips
Tanya Cheeke @tanyacheeke.bsky.social · 04/05/2026
Devastating loss of Dr. Adriana Romero-Olivares this week. She was an amazing mycologist, a leader in her field, & my friend & collaborator. This is a tremendous loss for mycology, science, & the world. There is a meal train for her husband & two small children www.mealtrain.com/trains/l3kg64
mealtrain.com
Meal Train for Jovani Catalan (Spouse of Adriana Romero Olivares)
Hi all, Please help out the family of Adriana Romero Olivares. Her husband, Jovani, and kids can be helped with meals over the next weeks as Adriana recovers.
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Reposted by Mark Phillips
bioRxiv Molecular Biology @biorxiv-molbio.bsky.social · 10/04/2026
Signal, noise, and sampling: How pool size and replication shape metabolomic inference www.biorxiv.org/content/10.64898/20…
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Reposted by Mark Phillips
Aide Macias-Muñoz @aidemm.bsky.social · 19/03/2026
Excited to share new results from our lab!! Research led by our research specialist Kelso assisted by undergrad Jo, they figured out how to increase egg yield in Hydra www.frontiersin.org/journals/eco...
frontiersin.org
Frontiers | Optimizing Egg Production by Trait Selection and Starvation in Hydra vulgaris
Hydra vulgaris is considered an effectively immortal freshwater Cnidarian. As a sistergroup to all Bilateria, studies of Cnidarian genomes offer valuable evo...
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Reposted by Mark Phillips
Genetics Society of America @genetics-gsa.bsky.social · 06/03/2026
New work in #G3journal from @maphillips.bsky.social and colleagues shows how selection intensity shapes the genomic architecture of adaptation in #yeast, highlighting the importance of caution when extrapolating results from lab studies to natural populations. buff.ly/T1O2RPJ
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Mark Phillips @maphillips.bsky.social · 05/03/2026
Recent work from the lab led by post doc Kenneth Arnold.
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Mark Phillips @maphillips.bsky.social · 16/01/2026
Work from post doc with Molly Burke on how selection intensity shapes the genomic architecture of adaptation. See: academic.oup.com/g3journal/ar...
academic.oup.com
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Mark Phillips @maphillips.bsky.social · 21/05/2025
Recent work from the lab led by post doc @drhubert.bsky.social. In flies where selection for early reproduction has led to accelerated aging, we find repeatable metabolome evolution involving shifts in energy metabolism. “Clock” models also appear to capture signals of biological age.
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Reposted by Mark Phillips
David L Hubert @drhubert.bsky.social · 21/05/2025
Excited to share our new paper with @maphillips.bsky.social‬ ‬published in @genomebiolevol.bsky.social: "Selection for Early Reproduction Leads to Accelerated Aging and Extensive Metabolic Remodeling in Drosophila melanogaster" Read more: doi.org/10.1093/gbe/...
doi.org
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Reposted by Mark Phillips
Aide Macias-Muñoz @aidemm.bsky.social · 20/05/2025
Happy to share that our Bougainvillia genome paper is out in G3! Genome assembly of Bougainvillia cf. muscus (Cnidaria: Hydrozoa) url:https://academic.oup.com/g3journal/article/doi/10.1093/g3journal/jkaf110/8137915
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Mark Phillips @maphillips.bsky.social · 28/02/2025
OSU Integrative Biology is seeking a new Department Chair/Full Professor. See link for details: jobs.oregonstate.edu/postings/165194. Please share with anyone you know who might be interested.
jobs.oregonstate.edu
Department Head and Professor
The Department of Integrative Biology within the College of Science invites applications for a Department Head, with an accompanying Full Professor appointment. The incumbent will hold two appointment...
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Reposted by Mark Phillips
Aide Macias-Muñoz @aidemm.bsky.social · 19/12/2024
Please share! I am hiring a postdoc in Evolutionary Development to join our lab 🧪 🥼 🧬 recruit.ucsc.edu/JPF01855 initial reviews begin Jan 31st (to be adjusted in the ad)
recruit.ucsc.edu
Postdoctoral Scholar in Evolutionary Development
University of California, Santa Cruz is hiring. Apply now!
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Reposted by Mark Phillips
Patrick Phillips @patrickphillips.bsky.social · 14/11/2024
I started an Aging Research starter pack. Feels very sparse right now, so (1) let me know who I missed and (2) we need to recruit a few folks who abandoned science twitter some time ago back into the fold. go.bsky.app/PcreQSa
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Mark Phillips @maphillips.bsky.social · 01/08/2024
Recently learned my NIH MIRA proposal to study the factors that shape/underlie complex trait variation using Drosophila experimental evolution will be funded. Looking to fill postdoc position in the near future. Please reach out if interested.
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