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Mohamed Shehata

@shehata92.bsky.social
76 followers 75 following 20 posts

Post-doctoral research scholar at @RommieAmaro's lab @UCSanDiego . . Computational chemist & biophysicist. . . sites.google.com/view/moshehata/home

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Reposted by Mohamed Shehata
Dr. Fiona @fionachembot.bsky.social · 01/04/2025
LOOK AT THIS PHENOMENAL WORK BY Mo and Lorenzo!! <3 great work to them!!
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CompBioPhys @compbiophys.bsky.social · 01/04/2025
🧐 Are you a computational physicist and expert in probability theory? 👉 Contribute to our project "Theory and Algorithms for Structure Determination from Single Molecule X-Ray Scattering Images" as PhD student or Postdoc! 🔗 Check our job advert for more details www.mpinat.mpg.de/4988122/09-2...
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Reposted by Mohamed Shehata
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 29/03/2025
Another epic #glycotime accomplishment from @rommieamaro.bsky.social and coworkers @UCSD
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Rommie Amaro @rommieamaro.bsky.social · 28/03/2025
✨✨ It's #glycotime for #HIV Env ✨✨ N-linked glycans modulate flexibility & MPER epitope exposure #glycotime Huge effort by @shehata92.bsky.social @lcasalino88.bsky.social with cryoET of Env in VLPs by @thevillalab.bsky.social & team 💪 Would love feedback! www.biorxiv.org/content/10.1...
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Mohamed Shehata @shehata92.bsky.social · 04/03/2025
#compchem
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Reposted by Mohamed Shehata
Briggs Group @briggsgroup.bsky.social · 28/02/2025
Mature #HIV-1 contains >2000 copies of “spacer peptide 2”, but we didn’t know why. We now see that SP2 binds the matrix protein and triggers the change into its mature arrangement. Summary video from @margotriggi.bsky.social
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Mohamed Shehata @shehata92.bsky.social · 23/02/2025
The letter count here is frustrating but this some my after dinner espresso thoughts today!
The letter count here is frustrating but this some my after dinner espresso thoughts today!
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Mohamed Shehata @shehata92.bsky.social · 15/02/2025
Roses are red , roses are blue , depending on their velocity relative to you. Happy Valentine's Day
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Mohamed Shehata @shehata92.bsky.social · 12/02/2025
“Injustice anywhere is a threat to justice everywhere” -Martin Luther King
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Reposted by Mohamed Shehata
Denis Wirtz @deniswirtz.bsky.social · 12/02/2025
"NIH admit freezing is illegal, will resume issuing grants" popular.info/p/breaking-n...
popular.info
BREAKING: NIH admits funding freeze is illegal, will resume issuing grants
An internal memo issued February 12 was obtained by Popular Information.
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Rommie Amaro @rommieamaro.bsky.social · 10/02/2025
Attorneys general argue that the NIH’s new policy violates the Administrative Procedure Act & ignores congressional powers by retroactively modifying existing contracts that set IDC rate between the federal government & research institutions www.statnews.com/2025/02/10/n...
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Mohamed Shehata @shehata92.bsky.social · 10/02/2025
🤣🤣
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Giulia Palermo @giuliapalermo.bsky.social · 08/02/2025
New paper from our lab @naturecomms.bsky.social! We reveal the dynamics and mechanism of target DNA traversal in #CRISPR Cas12a, a conundrum in the field! nature.com/articles/s41... #compchem We thank the amazing #HPC resources of PSC #Anton2 and SDSC
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Mohamed Shehata @shehata92.bsky.social · 10/02/2025
www.statnews.com/2025/02/08/n...
statnews.com
The NIH’s drastic cut to indirect cost rates is a critical threat to U.S. research infrastructure
The drastic reduction in indirect costs is not a path to innovation or cost savings — it’s a threat to U.S.’s position as global leader in medical research.
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Mohamed Shehata @shehata92.bsky.social · 02/02/2025
Today marks 3 years of postdoc—‘Somewhere, something incredible is waiting to be known.’ Here’s to more discoveries, coffee, and data crunching... mostly the coffee.😀 🚀☕💻 #PostdocLife #compchem
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Mohamed Shehata @shehata92.bsky.social · 27/01/2025
#compchem
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Reposted by Mohamed Shehata
Rommie Amaro @rommieamaro.bsky.social · 17/01/2025
Awesome mixed resolution simulation supporting amazing structural work 😍 Congrats to @becklab.bsky.social and @hummerlab.bsky.social ! www.cell.com/cell/fulltex...
cell.com
Passage of the HIV capsid cracks the nuclear pore
Cone-shaped HIV-1 capsids with largely intact lattices accumulate at and pass through nuclear pores in primary human macrophages. The nuclear pores can crack open upon passage of the HIV-1 capsid, pos...
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Mohamed Shehata @shehata92.bsky.social · 17/01/2025
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Mohamed Shehata @shehata92.bsky.social · 15/01/2025
I had a meeting with RMSD and RMSF and they were very mean😃 #compchem
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Mohamed Shehata @shehata92.bsky.social · 10/01/2025
The concept of entropy never fails to amaze me.
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Reposted by Mohamed Shehata
Martin Vögele @martinvoegele.bsky.social · 08/01/2025
Cryptic pockets are hidden binding sites in proteins that are not visible in their standard ("apo") structure and only stable in the presence of the right ligand. Here, Bemelmans et al. review how scientists use computer algorithms to detect them. www.sciencedirect.com/science/arti... 🧪 #CompChem
sciencedirect.com
Computational advances in discovering cryptic pockets for drug discovery
A number of promising therapeutic target proteins have been considered “undruggable” due to the lack of well-defined ligandable pockets. Substantial r…
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Reposted by Mohamed Shehata
Janet Iwasa @jiwasa.bsky.social · 07/01/2025
I'm happy and humbled to take on a new role with @rcsbpdb.bsky.social. I'll be continuing David Goodsell's work on the Molecule of the Month, starting with my first article on Assembly Line Polyketide Synthases! Check it out (animation included!) pdb101.rcsb.org/motm/301
pdb101.rcsb.org
PDB101: Molecule of the Month: Assembly Line Polyketide Synthases
Large multienzyme complexes that synthesize diverse small molecules in a stepwise manner.
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Mohamed Shehata @shehata92.bsky.social · 01/01/2025
Happy New Year! 2024 brought moments of growth, gratitude, and connection—reuniting with my family and navigating every peak and valley. Thankful to God, mentors, and the privilege of studying life atom by atom. Here’s to 2025: embracing challenges, breaking limits, and chasing the extraordinary. 🚀💥
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Mohamed Shehata @shehata92.bsky.social · 15/12/2024
It matters who does science Scientists should embrace their humanity rather than pretending that they are a bunch of automatons who instantly reach perfectly objective conclusions. www.science.org/content/blog...
science.org
It matters who does science
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Reposted by Mohamed Shehata
Martin Vögele @martinvoegele.bsky.social · 13/12/2024
The inside of a cell is incredibly crowded! With advancing computing power and smart algorithms, this complex world is becoming more accessible through simulations. This review summarizes the current state of modeling macromolecular crowding: pubs.acs.org/doi/10.1021/... #CompChem
pubs.acs.org
Recent Progress in Modeling and Simulation of Biomolecular Crowding and Condensation Inside Cells
Macromolecular crowding in the cellular cytoplasm can potentially impact diffusion rates of proteins, their intrinsic structural stability, binding of proteins to their corresponding partners as well ...
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Mohamed Shehata @shehata92.bsky.social · 13/12/2024
😅 #science #academia
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Mohamed Shehata @shehata92.bsky.social · 11/12/2024
my daily writing plan.. #academic
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Mohamed Shehata @shehata92.bsky.social · 09/12/2024
Looking back at this post from five months ago, it feels even more relevant today. With AI reshaping computational chemistry, unlocking opportunities once unimaginable, it’s a thrilling yet humbling time—full of excitement for the future and uncertainty about the challenges ahead.
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Mohamed Shehata @shehata92.bsky.social · 07/12/2024
First post on Bluesky—Sitting on the pyramids, a reminder of what humans can achieve. As an Egyptian scientist, I’m inspired to push boundaries, fueled by the legacy of a civilization that never stopped reaching higher.
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