npj Antimicrobials and Resistance - Addressing the dual-use of antifungals and fungal antimicrobial resistance (fAMR) through a One Health approach

Researchers from Imperial College London have conducted the U.K.'s largest-ever longitudinal study of indoor fungal air pollution, revealing that homes are active fungal ecosystems rather than passive...

A looming public health crisis may be spreading from Britain’s fields to its hospitals, a experts  -which include University of Manchester scientists-  have warned — with common farm chemicals potenti...

Researchers from Imperial College London have conducted the UK’s largest-ever longitudinal study of indoor fungal air pollution, revealing that...

Drivers of fungal metabolic diversity are incompletely understood. Here, the authors conduct a global genomics study of over 1,000 pathogenic fungi to show that geography shapes the metabolic diversity in Aspergillus flavus revealing how climate drives fungal chemical adaptive evolution.

Trials of drugs to fight deadly resistant infections are advancing, but they might fall victim to overuse of agricultural fungicides just like their predecessors.

What? F1AMR Network Scientific Meeting When? Thursday May 7th 2026Where? University of Manchester, UK At this fully hybrid event, we will hear presentations from colleagues in research, industry and t...

Drug-resistant fungal disease must be addressed in the 2026 update to the Global Action Plan on Antimicrobial Resistance

Pollution is ‘silent accelerator that robs individuals of their healthiest years’, say researchers

Amid growing evidence of fungi’s key role in ecosystems and storing carbon, African scientists are championing the need to preserve ‘funga’ as much as flora and fauna

Bifrost graph gene caller. Contribute to bacpop/ggCaller development by creating an account on GitHub.

Researchers have launched a new data science challenge aimed at improving the ability of NHS hospitals to anticipate and prevent severe patient harm.

Large mobile genetic elements known as Starships act as vehicles for transferring transposable elements (TEs) between fungi. Here, Griem-Krey et al. show that these ‘hitchhiking’ TEs can drive rapid e...

Candida ( Candidozyma ) auris is a critical priority fungal pathogen that emerged two decades ago near simultaneously on multiple continents. Since emergence, C. auris resistance to all four classes of antifungal drugs has been described, including pan-drug resistant isolates, sometimes evolving in-patient. Here, we confirm the first isolation of C. auris from Antarctica and show cold-adapted phenotypes and an affinity for binding to nylon. We also provide evidence to suggest mutator phenotypes contribute to the rapid evolution in C. auris and are responsible for the emergence of multiple, distinct genetic clades worldwide. Isolates in clades I, III and IV with a mutator phenotype displayed elevated mutation rates compared to non-auris Candida species. This phenotype had a complex genetic basis and was associated with drug resistance mutations. We postulate that the mutator phenotype has a significant effect on evolutionary potential and is responsible for the emergence and rapid spread of drug-resistance C. auris and novel genetic clades. ### Competing Interest Statement This work was partially support by a Wellcome Trust Institutional Strategic Fung Springboard Fellowship awarded to JR. PH and JR were funded through a JPIAMR IMPACT grant (JPIAMR2024_IMPACT-197 Consortium grant: FuGACI) and the Dutch Organisation for knowledge and innovation in health, healthcare and wellbeing (ZonMw) under project number 10570172410003. NvR is supported by a Wellcome Trust fellowship (226408/Z/22/Z). MCF is a fellow of the Canadian Institute for Advanced Research (CIFAR). RAF is supported by a Wellcome Trust Career Development Award (225303/Z/22/Z). JLS is a Howard Hughes Medical Institute Awardee of the Life Sciences Research Foundation. SD and HG are supported by the MRC Centre for Medical Mycology at the University of Exeter (MR/N006364/2 and MR/V033417/1), and the MRC Doctoral Training Grant (MR/P501955/2), and the NIHR Exeter Biomedical Research Centre. The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care. We also thank the Exeter Sequencing Service facility and support from Wellcome Trust Institutional Strategic Support Fund (WT097835MF), Wellcome Trust Multi User Equipment Awards (WT101650MA and 218247/Z/19/Z), Medical Research Council Clinical Infrastructure Funding (MR/M008924/1) and BBSRC LOLA award (BB/K003240/1), as well as the University of Exeter High-Performance Computing (HPC) facility, funded by the UK MRC Clinical Research Infrastructure Initiative (award number MR/M008924/1). Wellcome Trust, https://ror.org/029chgv08, Strategic Fung Springboard, 226408/Z/22/Z, 225303/Z/22/Z JPI-AMR, JPIAMR2024_IMPACT-197 Consortium grant: FuGACI ZonMw, The Dutch Organisation for knowledge and innovation in health, healthcare and well-being, 10570172410003 CIFAR Howard Hughes Medical Institute Awardee of the Life Sciences Research Foundation MRC Centre for Medical Mycology at the University of Exeter, MR/N006364/2, MR/V033417/1 MRC Doctoral Training Grant, MR/P501955/2 NIHR Exeter Biomedical Research Centre BBSRC, BB/W009625/1 MRC, MR/4002163/1

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Abstract. Transposable elements (TEs) are found in nearly all eukaryotic genomes. Despite significant advances in the sequencing of genomes, TE resources r

Amplicon sequencing typically results in a wide distribution in the number of sequences obtained from each sample. How best to account for this variation has been a persistent problem in the microbial...

Long-read sequence assemblies from metagenomes contain frequent errors.

The UK’s approach to food makes it increasingly vulnerable in an unstable world. A great food transformation with a focus on resilience is urgently needed, argues Paul Behrens Last week the UK gover...

We wish to appoint a PostDoctoral Research Associate to an exciting project exploring the assembly, stability and function of microbial decomposer communities.