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Sayan Das (he/him)

@s4yandas.bsky.social
388 followers 883 following 6 posts

Coffee mug humorist | #scicomm enthusiast| UMN BMBB grad student| Hafenstein Lab| Cryo-EM ❄️ | Structural virology 🦠 | Opinions of my own

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Reposted by Sayan Das (he/him)
Lars-Anders Carlson @lacarlson.bsky.social · 08/12/2025
We will announce a #postdoc opening in January. Cryo-ET and virus replication. If you're interested you can DM or email me already now. More info will follow!
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Reposted by Sayan Das (he/him)
giovanniconsoli.bsky.social @giovanniconsoli.bsky.social · 11/10/2025
Have you ever looked at the night sky and wondered if there’s a chlorophyll f in the reaction centre of Photosystem I from far-red light adapted cyanobacteria? 🦠 Well, we did (don’t judge) and the work that followed is now out as a First Release in @science.org www.science.org/doi/10.1126/...
science.org
Locating the missing chlorophylls f in far-red photosystem I
The discovery of chlorophyll f-containing photosystems, with their long-wavelength photochemistry, represented a distinct, low-energy paradigm for oxygenic photosynthesis. Structural studies on chloro...
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Reposted by Sayan Das (he/him)
The Daum Lab @daumlab.bsky.social · 06/10/2025
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
science.org
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
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Reposted by Sayan Das (he/him)
Nature Methods @natmethods.nature.com · 29/08/2025
A laser flash melting procedure, followed by rapid revitrification, provides a simple approach to help mitigate the preferred orientation problem that plagues cryo-EM analysis. www.nature.com/articles/s41...
nature.com
Laser flash melting cryo-EM samples to overcome preferred orientation - Nature Methods
Individual proteins tend to adopt preferred orientations when subjected to vitrification for cryo-electron microscopy analysis. A laser flash melting procedure followed by rapid revitrification provid...
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Reposted by Sayan Das (he/him)
Daniel Hurdiss @danielhurdiss.bsky.social · 15/07/2025
Interested in our recent norovirus NS3 work? 👇 Join us to dig deeper! I'm recruiting a PhD candidate to investigate NS3's role in viral replication and assembly using #cryoEM, #cryoET, and other complementary techniques. 🔗 tinyurl.com/4f3t3aae Please share! 🙏
tinyurl.com
PhD Candidate in Structural Virology and Antiviral Development
We are seeking a PhD candidate to elucidate the role of AAA+ ATPases in the viral replication cycle as part of the recently funded ERC StG project PicAAA.
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Reposted by Sayan Das (he/him)
The Ferrari Lab @theferrarilab.bsky.social · 09/07/2025
Powassan virus is a scary emerging tick-borne virus that causes neurological disease. It is great to see that my @ciddpsu.bsky.social colleagues are on top of it. www.psu.edu/news/researc...
psu.edu
Structure of tick-borne virus revealed at atomic resolution for the first time | Penn State University
Rates of the Powassan virus infections — which can cause seizures and paralysis — are increasing across North America. Researchers from Penn State, the University of Minnesota and the U.S. Department ...
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Sayan Das (he/him) @s4yandas.bsky.social · 09/07/2025
New in @science.org We built a safe, atomic-resolution version of the Powassan virus—a deadly tick-borne #flavivirus with no vaccine. ✅ First structure ever ✅ Safe to handle (BSL-2) ✅ Platform for vaccines & antivirals Let me show you 🧵 (1/5) Link: www.science.org/doi/10.1126/...
science.org
Atomic-resolution structure of a chimeric Powassan tick-borne flavivirus
The 2.8-Å resolution structure is presented for a chimeric construct of an emerging tick-borne flavivirus, Powassan virus.
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