Antisense oligonucleotides (ASOs) can modulate gene expression at the mRNA level, providing the ability to tackle conventionally undruggable targets and usher in an era of personalized medicine. A key...

Join Dr Grinberg’s team at Mayo Clinic exploring sleep dysfunction in neurodegenerative diseases, with advanced training and exceptional career prospects.

Background Tauopathies represent a diverse group of neurodegenerative disorders characterized by the abnormal aggregation of the microtubule-associated protein tau. Despite extensive research, the mec...

Millions of ribosomes are packed within mammalian cells, yet we lack tools to visualize them in toto and characterize their subcellular composition. In this study, we present ribosome expansion micros...

Check out one of my favorite techniques of the last few years - the NanoSplits paper here!   The first preprint of this study is somewhere...

Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.

Trieste, Italy 9 – 11 September 2025

FUS is an RNA binding protein mutated in amyotrophic lateral sclerosis (ALS), a neurodegenerative di

Frontotemporal dementia (FTD) and Alzheimer's disease are the most common forms of early-onset demen

The neurophysiological processes regulated by meningeal lymphatic function remain unclear. das Neves et al. showed that meningeal lymphatic dysfunction leads to loss of mature oligodendrocytes and dem...