If you haven't seen our recent paper on the Fragment-Based Discovery of RNA competitive inhibitors of the DEAH-Box RNA helicase DHX8 yet, check out this excellent summary by Daniel Erlanson on the Practical Fragments Blog. practicalfragments.blogspot.com/2026/08/frag...
practicalfragments.blogspot.com
Fragments vs DHX8: towards a chemical probe
RNA helicases present an intriguing but challenging opportunity for drug discovery. Their importance for cell growth makes them attractive c...