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Rafa F Leiro

@rfleiro.bsky.social
883 followers 212 following 2 posts

Structural & Molecular biologist Group leader @ CNIO Genome Integrity & Structural Biology Lab

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Reposted by Rafa F Leiro
AI x Bio Discovery @aixbiobot.bsky.social · 16/09/2025
Automated and modular protein binder design with BinderFlow [new] Streamlines protein binder design by providing a modular, automated, and easily monitored pipeline, increasing accessibility and scalability.
Automated and modular protein binder design with BinderFlowFigure 1Figure 2
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Reposted by Rafa F Leiro
bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 16/09/2025
Automated and modular protein binder design with BinderFlow www.biorxiv.org/content/10.1101/202…
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Reposted by Rafa F Leiro
Julio Abril Garrido @jabrilgarrido.bsky.social · 22/03/2025
Happy to have hosted @rfleiro.bsky.social in @mpi-nat.bsky.social and hear the cool science he is doing in @cniostopcancer.bsky.social. Watch out for him!
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Reposted by Rafa F Leiro
Alexey Amunts @amunts.bsky.social · 15/03/2025
See you in Madrid! Speakers include: @costalaboratory.bsky.social @piratefernandez.bsky.social @nhoitsma.bsky.social @kellythd-nguyen.bsky.social @lapassmore.bsky.social @alessandrovannini.bsky.social @oscarllorca.bsky.social @rfleiro.bsky.social @nogaleslab.bsky.social www.cnio.es/en/eventos/m...
cnio.es
Machines acting on DNA and RNA, a molecular mechanistic perspective (#CFM_MolMech)
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Reposted by Rafa F Leiro
cniostopcancer.bsky.social @cniostopcancer.bsky.social · 18/02/2025
🔎#CFM_MolMech: a meeting exploring the integration of structural, biochemical, and biophysical insights into cryo-EM advances that reveal molecular machines behind DNA/RNA processes. 👥 Meet the organisers: @oscarllorca.bsky.social, @rfleiro.bsky.social and @nogaleslab.bsky.social. 📆May 28-30th
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Reposted by Rafa F Leiro
cniostopcancer.bsky.social @cniostopcancer.bsky.social · 05/02/2025
🔴⚠CNIO-CaixaResearch Frontiers Meetings: Machines acting on DNA and RNA, a molecular mechanistic perspective. 📆May 28-30th 👥 @oscarllorca.bsky.social, @rfleiro.bsky.social and @nogaleslab.bsky.social. 🔗https://www.cnio.es/eventos/machines-acting-on-dna-and-rna-a-molecular-mechanistic-perspective/
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Reposted by Rafa F Leiro
cniostopcancer.bsky.social @cniostopcancer.bsky.social · 16/01/2025
“El CNIO ha estado construyendo una base importante en crio-microscopía electrónica”, dice Tafur; “la experiencia de grupos como el de @rfleiro.bsky.social y el @oscarllorca.bsky.social pueden complementarse con la nuestra de manera muy enriquecedora”, explica Tafur. www.cnio.es/noticias/el-...
cnio.es
El CNIO incorpora un nuevo grupo para ‘fotografiar’ a nivel atómico y en 3D las estructuras que hacen invasivas a las células cancerosas
Las células se adaptan a las condiciones del ambiente y a los nutrientes que tienen a su disposición. Lo hacen por medio de grupos de proteínas -técnicamente se llaman complejos de proteínas-, que det...
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Reposted by Rafa F Leiro
Timothy P. Jenkins @tpjenkins.bsky.social · 15/01/2025
🚨 Revolutionising Snakebite Treatments with AI-Designed Proteins 🐍 I'm proud to share our latest study published in hashtag#Nature, driven by Susana Vazquez Torres, and co-led by David Baker (Institute for Protein Design, University of Washington) and myself.
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Reposted by Rafa F Leiro
Danve Castroverde @danvec.bsky.social · 15/01/2025
Pretty cool work on designing antivenoms de novo! 😱😻👏 www.nature.com/articles/s41...
nature.com
De novo designed proteins neutralize lethal snake venom toxins - Nature
Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible an...
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Reposted by Rafa F Leiro
DNA replication and Genome Integrity Lab @ CIB-CSIC @bermejolab.bsky.social · 13/01/2025
We are still looking for candidates to apply for PhD and postdoctoral fellowships. Get in touch with us if you are interested in learning about the functional architecture of replisome protection using strand-specific genomics and AI modeling of molecular interactions!!!
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Reposted by Rafa F Leiro
Corresponsables @corresponsables.bsky.social · 09/01/2025
🔬El #CNIO incorpora un nuevo grupo para ‘fotografiar’ a nivel atómico y en 3D las estructuras que hacen invasivas a las células cancerosas. www.corresponsables.com/actualidad/c...
corresponsables.com
El CNIO incorpora un nuevo grupo para ‘fotografiar’ a nivel atómico y en 3D las estructuras que hacen invasivas a las células cancerosas
Las células se adaptan a las condiciones del ambiente y a los nutrientes que tienen a su disposición. Lo hacen por medio de grupos de proteínas -técnicamente se llaman complejos […]
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Reposted by Rafa F Leiro
Infosalus @infosalus.com · 09/01/2025
El CNIO incorpora un grupo para fotografiar a nivel atómico las estructuras que hacen invasivas a las células cancerosas
infosalus.com
El CNIO incorpora un grupo para fotografiar a nivel atómico las estructuras que hacen invasivas a las células cancerosas
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Reposted by Rafa F Leiro
oscarllorca.bsky.social @oscarllorca.bsky.social · 10/01/2025
REGISTRATION OPEN!! - CNIO meeting, Machines acting on DNA and RNA, 2025 May 28-30th in Madrid, organized by @nogaleslab.bsky.social , @rfleiro.bsky.social , and @oscarllorca.bsky.social
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Reposted by Rafa F Leiro
Sjors Scheres @sjorsscheres.bsky.social · 26/12/2024
I don't know what happened here, but I do know that @cniostopcancer.bsky.social is one of very few places in Spain for excellent science. Care should be taken to protect the institute and its scientists from inaccurate reporting. www.eldiario.es/sociedad/mar...
eldiario.es
Maria Blasco, directora del CNIO: “Soy víctima de una campaña, ni un euro contra el cáncer se ha destinado al arte”
La responsable del mayor centro de investigación contra el cáncer de España, en el ojo del huracán por su gestión, responde a las informaciones que apuntan a desviaciones de fondos y acoso laboral en ...
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Reposted by Rafa F Leiro
Chaitanya K. Joshi @chaitjo.bsky.social · 13/12/2024
Watched this really insightful talk by @sjorsscheres.bsky.social and thinking why on earth they'd decide to have a random keyboard as decoration -- 13 mins in Sjors tells why and its kinda heartwarming for computational folks! youtu.be/SoXAac2HIrY?...
youtu.be
Sjors Scheres - LMB Through the Years
YouTube video by MRC Laboratory of Molecular Biology
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Rafa F Leiro @rfleiro.bsky.social · 10/11/2024
hello world! looking forward to a more sane and focused scrolling and interactions 😊
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