iiinova — where your digital self keeps evolving

Reposted by Raúl Padrón

Charlie Scarff @scarfflab.bsky.social · 01/05/2026

Also great work from the @raulpadron.bsky.social and Craig labs on how mavacamten and OM modulate the auto-inhibited off-state of myosin published in the same issue! www.science.org/doi/10.1126/...

science.org

Cryo-EM reveals how cardiomyopathy therapeutic drugs modulate the myosin motors of the heart

High-resolution structures reveal how cardiomyopathy drugs modulate myosin to suppress or enhance human heart contraction.

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Reposted by Raúl Padrón

cryoEM papers @cryoempapers.bsky.social · 17/06/2025

Annotating the X-ray diffraction pattern of vertebrate striated muscle www.biorxiv.org/content/10.1101/2025.06.11.659175v1 #cryoEM

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Reposted by Raúl Padrón

Dylan Burnette @mag2art.bsky.social · 31/03/2025

Interested in how the heart generates contractile forces to pump blood? Then take a look at our new paper "α- and β-myosin II can be non-uniformly distributed within the cardiac sarcomere". #CellBiology www.sciencedirect.com/science/arti...

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Reposted by Raúl Padrón

Altmetric @altmetric.com · 18/11/2024

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics

docs.bsky.app

Action Intent Links | Bluesky

Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...

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Reposted by Raúl Padrón

Anthony Hessel, PhD @hesselanthony.bsky.social · 24/11/2024

Working hard this weekend at the P03 beamline, PetraIII synchrotron, DESY, Hamburg. Really amazing multi-national team uncovering the secrets of the heart! @droch.bsky.social @edgarnollet.bsky.social @ambiotech.us

Xray group getting equiptment training at the beamline from AMB CTO Khoi Nguyen.

Imagine of an extracted mouse pappilary attached to a sample holder.

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Reposted by Raúl Padrón

Julien Ochala @droch.bsky.social · 03/01/2025

I am trying to gauge how much interest is given to muscle wasting in critical illness within the scientific community? This is a very heterogenous condition and would be keen on join forces to further understand it!!!

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Reposted by Raúl Padrón

Anthony Hessel, PhD @hesselanthony.bsky.social · 13/02/2025

Excited to be part of a consortium application to the European Rare Disease Research Alliance (ERDERA), lead by Coen Ottenheijm (NL). Among the group, I point out @droch.bsky.social, as we seem to be finding ourselves more and more on the same applications. Our methods really pair well together!

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Reposted by Raúl Padrón

UMass Chan Medical School @umasschan.bsky.social · 16/03/2025

In this Q&A with #NobelPrize recipient Victor R. Ambros, PhD, writer Patrick Boyle comments, “While the science behind the discovery of #microRNA is remarkable, also remarkable is what the discovery illustrates about the importance of basic science research.” direc.to/mEkL @aamctoday.bsky.social

direc.to

Nobel laureate: Basic science research is critical for medical progress

Victor Ambros, PhD, co-winner of the 2024 prize in medicine, says public support and scientific fellowship fueled discovery of an RNA that regulates genes.

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