Mechanism of the myosin inhibitor mavacamten is revealed by cryo-EM and cross-linking studies.

PhD Project - Unravelling the mechanisms of cardiac myosin function in health and disease at University of Leeds, listed on FindAPhD.com

PhD Project - Unravelling the mechanisms of action of cardiac myosin modulators in health and heart disease at University of Leeds, listed on FindAPhD.com

A study using time-resolved cryogenic electron microscopy reveals the swinging lever mechanism of myosin, providing information on the molecular basis behind the production of force and movement by my...

Most sudden cardiac deaths in young people arise from hypertrophic cardiomyopathy, a genetic disease of the heart muscle, with many causative mutations found in the molecular motor beta-cardiac myosin...

PhD Project - Making and breaking myosin filaments: How smooth muscle cells modulate their contractile behaviour. at University of Leeds, listed on FindAPhD.com

PhD Project - Unravelling the mechanisms of cardiac myosin function in health and disease through molecular dynamic simulation and electron microscopy at University of Leeds, listed on FindAPhD.com

PhD Project - Unravelling the mechanisms of cardiac myosin function in health and disease through molecular dynamic simulation and electron microscopy at University of Leeds, listed on FindAPhD.com

PhD Project - Making and breaking myosin filaments: How smooth muscle cells modulate their contractile behaviour. at University of Leeds, listed on FindAPhD.com

The Cheney Scholarship 4-year PhD Scheme in in situ structural biology Applications are now invited for up to 4 new scholarships, commencing in October 2025. The application deadline is Tuesday 3rd De...

Join the Astbury Centre for a day focused on taking drug discovery into cells and tissues with the aim of driving translation.

Myosins are essential for producing force and movement in cells through their interactions with F-actin. Generation of movement is proposed to occur through structural changes within the myosin motor ...