Protein aggregation is an obstacle for engineering effective recombinant proteins for biotechnology and therapeutic applications. Predicting protein aggregation propensity remains challenging due to t...

YouTube video by Science Communication Lab

YouTube video by Chalmers AI4Science

Protein conformational entropy plays a vital role in functions like binding and catalysis. This Perspective discusses three ways macromolecules use conformational entropy: prepaying entropic costs, re...

The CASP16 experiment provided the first opportunity to benchmark AlphaFold3. In contrast to AlphaFold2, AlphaFold3 can predict the structure of non-protein molecules, and according to the benchmark p...

Amino acid insertions and deletions (indels) are among the most common protein mutations and necessitate changes to a protein’s backbone geometry. Examining how indels affect protein folding stability...