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The Align Foundation @alignbio.bsky.social · 31/03/2026

📢 Data Release Tuesday: Align TEV Protease Dataset 📊 We’re expanding the The Align Foundation data ecosystem again with ~30,000 high-quality GROQ-seq data points capturing TEV protease sequence–function relationships at scale.

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The Align Foundation @alignbio.bsky.social · 24/03/2026

📢 Public Data Release: Align T7 RNA Polymerase Dataset. 📊The data keeps coming at Align! We’re excited to release our T7 RNA polymerase dataset, adding ~35,000 unique GROQ-seq data points to the growing Align data ecosystem, capturing sequence–function relationships across variants at scale.

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The Align Foundation @alignbio.bsky.social · 17/03/2026

🚀 Public Data Release: GROQ-seq Transcription Factor Dataset We’re excited to announce the public release of The Align Foundation's first GROQ-seq dataset, one of the largest high-resolution transcription factor datasets of its kind.

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The Align Foundation @alignbio.bsky.social · 24/02/2026

Align and Google DeepMind are partnering to build AI-ready datasets & evaluations for the future of predictive #AMR biology. Researchers worldwide can submit concepts through March 31 with roadmapping workshops coming to North America + APAC this spring. 🔗 docs.google.com/forms/d/e/1F...

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The Align Foundation @alignbio.bsky.social · 15/01/2026

In partnership with @pioneerlabs.bsky.social, we’re proposing Tesseract: a large-scale, open microbial phenomics dataset to functionally annotate microbial genomes at scale. 🧬🤖 ✅5M diverse genes x 50 host strains × 100 conditions 🔗 Read the proposal:https://zenodo.org/records/17990299

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The Align Foundation @alignbio.bsky.social · 15/10/2025

1/5 To ensure the highest impact and participation, we are adjusting the timeline of the Protein Engineering Tournament. The Tournament will now begin on December 1st, 2025.

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Reposted by The Align Foundation

scverse @scverse.bsky.social · 26/08/2025

🧫 Meet the keynote speakers for the 2025 scverse conference! Erika Alden DeBenedictis, Co-founder of The Align Foundation & CEO of Pioneer Labs @erika-alden.bsky.social ‪ @alignbio.bsky.social @pioneerlabs.bsky.social #scverse #scverse2025 #StructuralBiology #Biotech #Stanford

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The Align Foundation @alignbio.bsky.social · 21/08/2025

📣 Evolutionary Scale is supporting the 2025 Protein Engineering Tournament! Teams get sponsored ESM inference through @evolutionaryscale.bsky.social's API (Forge), bringing frontier protein AI models into the competition. Level playing field, real experiments, open results. Register now 👇

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The Align Foundation @alignbio.bsky.social · 19/08/2025

Thrilled to welcome Amanda Reider Apel to The Align Foundation as Director of Protein Projects! 🚀 A biotech leader who builds high-impact science and thriving teams, she’ll drive protein engineering strategy while fostering a culture of innovation and collaboration.

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The Align Foundation @alignbio.bsky.social · 13/08/2025

Why PETase for our tournament? In 2024, the world made about 30 million tonnes of PET plastic, most from fossil fuels. PETase can degrade PET, but isn’t ready for industrial-scale waste. The challenge: design an improved variant that can change that. Register by Oct 17 alignbio.org/protein-engi...

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The Align Foundation @alignbio.bsky.social · 21/07/2025

1/4 We just published the 1st-year update on GROQ-seq: an open access, high-throughput experimental platform capable of testing hundreds of thousands of protein variants per run, running @ NIST and the DAMP Lab. Here’s what we built, learned, and what’s next: #GROQseq #syntheticbiology

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The Align Foundation @alignbio.bsky.social · 08/07/2025

1/4 🚀 Announcing the 2025 Protein Engineering Tournament. This year’s challenge: design PETase enzymes, which degrade the type of plastic in bottles. Can AI-guided protein design help solve the climate crisis? Let’s find out! ⬇️ #AIforBiology #ClimateTech #ProteinEngineering #OpenScience

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The Align Foundation @alignbio.bsky.social · 18/06/2025

🚨 Align × ATCC are partnering to build the world’s largest public microbial phenotyping dataset. ✅ 1K strains ✅ 1K conditions ✅ 1M reproducible experiments ✅ Open access This experimental platform will use high-throughput automation, linked to ATCC’s authenticated genomes.

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The Align Foundation @alignbio.bsky.social · 16/05/2025

Align's GROQ-seq platform just turned 1 🎂 it now supports 7 protein function projects across 6 labs worldwide. 300k variants measured per run @ <$0.05 each, and it works. Not theory. Real infrastructure. Open to the world. 🔗 1-year technical report → hubs.la/Q03mSrW_0

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The Align Foundation @alignbio.bsky.social · 28/04/2025

Measuring precise enzyme kinetics (like kcat and Km) is key to understanding enzyme function. But these measurements are most often conducted in singleplex in vitro assays - expensive and tough to scale. 1/7 🧵👇

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The Align Foundation @alignbio.bsky.social · 17/04/2025

Q1 at Align = ✅ Team doubled ✅ 65k GROQ-seq datapoints ✅ Genotype-by-Phenotype platform ✅ Global conf. circuit ✅ Tournament prep underway Get the full download → hubs.la/Q03hT_V60 #ProteinEngineering #AIxBiology #SynBio #OpenScience

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The Align Foundation @alignbio.bsky.social · 13/03/2025

🚀 New proposal from Align! The experimental platform aims to standardize #microbial #phenotyping & support predictive modeling. 🦠 Capturing data across 1k strains & 1k conditions; using BacterAI; generating high-quality datasets for ML @jensen_lab

zenodo.org

Genotype to Phenotype: Design of an Extensible Experimental Platform for Characterizing Microbes

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The Align Foundation @alignbio.bsky.social · 19/02/2025

We are gearing up for our 2025 Protein Engineering Tournament! 🧬 🏆 Have ideas on what the next community benchmarking competition for protein design and engineering should look like? 💡 💪 Join our organizing committee here: buff.ly/3ELqfrb

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The Align Foundation @alignbio.bsky.social · 09/01/2025

🚀 Collaborative, AI-Ready datasets would revolutionize life sciences and catalyze progress. Government funding plays a critical role in making this a reality. 📖 Read our policy memo here:

buff.ly

Kickstarting Collaborative, AI-Ready Datasets in the Life Sciences

The government should fund collaborative roadmapping, certification, collection, and sharing of large, high-quality datasets in life science.

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The Align Foundation @alignbio.bsky.social · 03/12/2024

🚀 News from Align! Today, we're sharing our proposal for building a predictive model of protein expression. Check it out here! ➡️ buff.ly/3OqtPZf ⬅️ 🌍✨#ProteinExpression #Bioengineering #Collaboration #MachineLearning #DataScience #AlignToInnovate

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The Align Foundation @alignbio.bsky.social · 26/11/2024

🌟 Congrats to Cradle on their Series B raise! 🌟 www.cradle.bio/blog/series-b

cradle.bio

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