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James Mason

@profjamesmason.bsky.social
142 followers 142 following 40 posts

Associate Dean Impact & Innovation Faculty of Life Sciences & Medicine, King's College London Antimicrobials (mostly peptides), nucleic acid delivery, microbial metabolomics

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Reposted by James Mason
Times Higher Education (THE) @timeshighered.bsky.social · 27/09/2026
Academics and caterers at the same table, eating from root to tip: campus project could lead to recipe book, in ‘important’ example of collaboration between professional services staff and researchers ow.ly/Fnxt50ZRv7Q
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UK Health Security Agency @ukhsa.bsky.social · 16/09/2026
Sharaine works at Porton Down, in what is sometimes called our 'top secret lab'. 🔬 🧪 Go behind the scenes and find out about her work on phages - a possible alternative treatment for antibiotics. 🧫
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Mark A. Hanson @hansonmark.bsky.social · 14/08/2026
HIRING MICROBIOLOGIST: effective start asap! The PDRA/PDRF (per xp) will investigate the interactions of bumblebee antimicrobial peptides (AMPs) with the gut microbiota & more. Our work has shown AMPs have striking specificity for ecological microbes. careers.exeter.ac.uk/vacancies/13... 1/2
careers.exeter.ac.uk
Postdoctoral Researcher Associate or Fellow in Cornwall | University of Exeter
View details and apply for this Postdoctoral Researcher Associate or Fellow vacancy in Cornwall. Postdoctoral Research Associate / Fellow This job is part of an Advanced Research + Inventio...
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James Mason @profjamesmason.bsky.social · 21/05/2026
English clubs to have won both the European Cup/Champions League and the UEFA Cup/Europa League: Liverpool, Manchester United, Chelsea and Aston Villa (new). #AVFC
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Andreas Peschel @andreaspeschel.bsky.social · 29/04/2026
You are an ambitious young scientist, on the verge to independence, in a research field related to our Cluster of Excellence @cmfi.bsky.social “Controlling Microbes to Fight Infections”? Join our vibrant, interactive scientific community in Tubingen. Repost and apply! www.nature.com/naturecareer...
nature.com
Independent Junior Research Group Leaders (m/f/d) - Tübingen, Baden-Württemberg (DE) job with Eberhard Karls Universität Tübingen | 12858473
The Cluster of Excellence EXC 2124 “Controlling Microbes to Fight Infections” (CMFI) at the University of Tübingen invites applications for Indepen...
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King's Faculty of Life Sciences & Medicine @kingslsm.bsky.social · 18/03/2026
Researchers @kingscollegelondon.bsky.social and @uniofsurrey.bsky.social have developed a new technique to measure the content of individual human immune cells infected with a model bacteria for Mycobacterium tuberculosis ⬇️ www.kcl.ac.uk/news/new-sin...
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James Mason @profjamesmason.bsky.social · 13/03/2026
MRC have announced their new approach to curiosity-driven research: www.ukri.org/news/mrc-cur... Boards gone (?) replaced with flexible panels and interviews. DPFS and Gap fund renamed.
ukri.org
MRC curiosity-driven research reopens with new approach
The Medical Research Council (MRC) unpauses curiosity driven research funding and improves the funding process.
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Tracy Palmer @proftracypalmer.bsky.social · 12/03/2026
2 year fellowship available in AMR research www.medicalresearchfoundation.org.uk/grants/antim...
medicalresearchfoundation.org.uk
Medical Research Foundation | Antimicrobial Resistance Research
Antimicrobial Resistance Research
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King's Faculty of Life Sciences & Medicine @kingslsm.bsky.social · 09/03/2026
Researchers at King’s have shown that a widely used cardiac arrest risk score can be applied before patients reach hospital, enabling paramedics to assess the risk of brain injury at an earlier stage of care www.kcl.ac.uk/news/algorit...
kcl.ac.uk
Algorithm allows paramedics to predict brain damage risk after cardiac arrest | King's College London
Researchers at King’s College London have shown that a widely used cardiac arrest risk score can be applied before patients reach hospital, enabling paramedics to assess the risk of brain injury at an...
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King's College London @kingscollegelondon.bsky.social · 20/02/2026
Interdisciplinary scientists at King's are using highly powerful magnets to drive new discoveries.🧲 The state of the art #NuclearMagneticResonance (#NMR) machine enables researchers to see what cannot be seen with the naked eye, at the atomic level. #ScienceAtKings @kingslsm.bsky.social
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Reposted by James Mason
King's College London @kingscollegelondon.bsky.social · 09/02/2026
Deaths due to synthetic opioids nitazenes could have been underreported by as much as a third. New research by @kingslsm.bsky.social sheds light on the UK’s growing opioid problem. www.theguardian.com/society/2026...
theguardian.com
Synthetic opioids may have caused hundreds more UK deaths than thought
Study find nitazenes, which are up to 500 times stronger than heroin, can degrade significantly in portmortem blood samples
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Reposted by James Mason
Arthur Snell @snellarthur.bsky.social · 09/02/2026
So Starmer, a man who never met Epstein but made a bad appointment, might resign. But Trump, his closest friend, fellow sex abuser and coverer-upper of his crimes, is going nowhere. That’s how it works, isn’t it?
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King's College London @kingscollegelondon.bsky.social · 23/01/2026
Researchers across King’s are making a profound impact on society – locally, nationally and across the world. The King’s Engaged Research Awards, held at the King’s Great Hall, celebrated this remarkable impact. ⬇️ www.kcl.ac.uk/news/winners...
kcl.ac.uk
Winners announced for the 2026 King's Engaged Research Awards | King's College London
Staff, students and community partners have celebrated public and community engagement at the King’s Engaged Research Awards ceremony.
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King's College London @kingscollegelondon.bsky.social · 19/01/2026
The One King’s Impact Fund is open for applications! 🌍 Open to students and staff at King's, the fund offers £25k–£50k to support projects tackling local and global challenges. 💡 Turn bold ideas into real-world impact. Apply by 1 April: www.kcl.ac.uk/impact/fund
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Harry Wallop @harrywallop.co.uk · 02/12/2025
Great culture can save lives. Literally. Amazing letter in today’s @thetimes.com about Tom Stoppard
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Charlie Hind @hindcharlie.bsky.social · 27/11/2025
Come work with me!!! Opportunity for a Senior Scientist to join our wonderful, friendly and productive team at UKHSA, Porton Down. Working as part of our Phage and Open Innovation Teams. Closing date 10th Dec. #job #microsky Please share with your networks :D www.healthjobsuk.com/job/UK/Londo...
healthjobsuk.com
Job vacancy: Senior Scientist - Phage, UK Health Security Agency, Salisbury | trac.jobs
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Reposted by James Mason
Nature Microbiology @natmicrobiol.nature.com · 26/11/2025
#NewResearch The permeability of bacterial porins is dynamically regulated by periplasmic proton and potassium concentrations, altering antibiotic resistance. #MicroSky #AMR 🦠 @andresfloto.bsky.social www.nature.com/articles/s41...
nature.com
Metabolic control of porin permeability influences antibiotic resistance in Escherichia coli - Nature Microbiology
The permeability of bacterial porins is dynamically regulated by periplasmic proton and potassium concentrations, altering antibiotic resistance.
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Freya Harrison @friendlymicrobe.bsky.social · 15/10/2025
PhD opportunity in my lab: exploring how commensals and pathogens build biofilm communities on endotracheal (ventilator) tubes. Microbial ecology, medical microbiology and fancy imaging! Co-supervised with the fabulous Saskia Bakker and Jeremy Webb warwick.ac.uk/fac/cross_fa... #MicroSky
warwick.ac.uk
Dr Freya Harrison
Dr Freya Harrison
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Freya Harrison @friendlymicrobe.bsky.social · 08/11/2025
What Rosalind Franklin truly contributed to the discovery of DNA’s structure. A really informative article, perfect for a weekend coffee read. www.nature.com/articles/d41...
nature.com
What Rosalind Franklin truly contributed to the discovery of DNA’s structure
Franklin was no victim in how the DNA double helix was solved. An overlooked letter and an unpublished news article, both written in 1953, reveal that she was an equal player.
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King's Faculty of Life Sciences & Medicine @kingslsm.bsky.social · 02/10/2025
What if ICU doctors could diagnose infections in hours, not days? A new test, developed from a PhD project at King's, now makes this possible.🔬 🔗 www.kcl.ac.uk/metagenomics...
kcl.ac.uk
Metagenomics testing: From PhD project to the ICU
A new diagnostic test that can detect a broad range of microorganisms in a single sample and give same-day results has been shown to improve the diagnosis and treatment of patients with…
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Reposted by James Mason
Andy Edwards @bugsinblood.bsky.social · 29/09/2025
Now published! www.nature.com/articles/s41... Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.
nature.com
Polymyxin B lethality requires energy-dependent outer membrane disruption - Nature Microbiology
The antibiotic polymyxin B requires bacterial metabolic activity to cause sufficient damage to the outer membrane to access the inner membrane, which it permeabilizes via an energy-independent mechanism to kill the cell.
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James Mason @profjamesmason.bsky.social · 29/09/2025
Exciting to see what impact will come from this in how all cause lung injuries are treated in the future.
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Professor Lesley Hoyles @bugsinyourguts.bsky.social · 13/09/2025
If you are UK-based and working on any aspect of microbiomes (human, plant, insect, soil, animal, ...), please do sign up to Microbiome-Net for details of networking, funding and training opportunities. forms.office.com/pages/respon...
forms.office.com
Microsoft Forms
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 07/08/2025
Please share my 1 min video on the importance of maintaining NIH funding of infectious diseases and drug discovery research vs rising antibiotic resistance Drastic budget cuts harm our health and imperil the next generation of scientists More @UCSanDiego “Behind Every Breakthrough” bit.ly/3FlXQs3
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 24/07/2025
Impressive paper in 𝘕𝘢𝘵𝘶𝘳𝘦 Describes a new sensory modality: "𝙉𝙀𝙐𝙍𝙊𝘽𝙄𝙊𝙏𝙄𝘾 𝙎𝙀𝙉𝙎𝙀" Links bacterial flagellin to appetite control Gut-Brain Circuit: flagellin activates TLR5 on PYY+ neuropod cells that synapse onto vagal neurons → feeding suppressed independent of microbiota, immunity, or metabolism
nature.com
A gut sense for a microbial pattern regulates feeding - Nature
A study reveals a gut–brain sensory pathway through which the microbial component flagellin activates neuropod cells in the colon to signal the brain and reduce feeding in mice.
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 21/07/2025
If high quality treatment is provided to everyone with bacterial infections + innovative new antibiotics funded ... By 2050: Health costs ⬇️ $97 billion The economy ⬆️ $960 billion Generated health benefits 🟰 $680 billion to countries Return on Investment 🟰 28 to 1 www.cgdev.org/publication/...
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Charlie Hind @hindcharlie.bsky.social · 21/07/2025
It is time to improve diagnostics of Urinary Tract Infections! We developed a new technology that can work out which antibiotic would be best suited to treat UTIs in <five hours rather than the >40 hours that it currently takes. www.sciencedirect.com/science/arti...
sciencedirect.com
Rapid impedance-based Antimicrobial Susceptibility Testing (iFAST) of Enterobacterales in urinary tract infections
Evidence-based antibiotic prescribing for urinary tract infections (UTIs) would increase treatment success and improve antibiotic stewardship. Current…
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Reposted by James Mason
King's College London @kingscollegelondon.bsky.social · 31/05/2025
We are pleased to announce a new clinical research fellowship at King’s to advance the nation’s metabolic health in honour of British broadcaster, author, and science journalist Dr Michael Mosley. @kingslsm.bsky.social | @kclalumni.bsky.social
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King's College London @kingscollegelondon.bsky.social · 22/05/2025
A new report has found that people with chronic obstructive pulmonary disease (COPD) feel like ‘second class citizens’. Launched today at the House of Commons, the report sets out the stark reality people with COPD face in securing diagnosis & accessing care. www.kcl.ac.uk/news/people-...
kcl.ac.uk
People with COPD feel like 'second class citizens', finds new report
A report from King’s College London sets out the stark reality people with chronic obstructive pulmonary disease (COPD) face in securing diagnosis and accessing care.
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Reposted by James Mason
King's College London @kingscollegelondon.bsky.social · 24/04/2025
Two thirds of adults were able to eat peanuts without an allergic reaction after taking part in ‘groundbreaking research’ at @kingslsm.bsky.social and @gstt-nhs.bsky.social. The study used daily doses of peanuts to desensitise patients with life-long allergy. www.kcl.ac.uk/news/daily-d...
kcl.ac.uk
Daily doses of peanuts tackle allergic reactions in adults
The first clinical trial to test whether adults allergic to peanuts can be desensitised has shown great success with two thirds of the cohort consuming the equivalent of four peanuts without reacting.
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James Mason @profjamesmason.bsky.social · 18/04/2025
Some important ground work for studying metabolism of the vaginal microbiota www.biorxiv.org/content/10.1...
biorxiv.org
Metabolism of Lactobacillus and Gardnerella vaginalis in vaginal defined media
Lactobacilli and Gardnerella vaginalis are key bacteria within the vaginal microbiota, significantly impacting its chemical environment. Accurately reproducing vaginal bacteria metabolism in vitro is ...
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Reposted by James Mason
Andy Edwards @bugsinblood.bsky.social · 17/04/2025
Polymyxin B lethality requires energy-dependent outer membrane disruption New preprint in collaboration with colleagues @ucl.ac.uk and @uniofnottingham.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
Polymyxin B lethality requires energy-dependent outer membrane disruption
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James Mason @profjamesmason.bsky.social · 26/03/2025
We are recruiting again - 20 AI+ Academic Fellowships www.kcl.ac.uk/jobs/role/ki...
kcl.ac.uk
King's AI+ Academic Fellowships (leading to an open-ended academic post)
King’s is making a major strategic investment into driving AI activity across our nine academic Faculties. Our ambition is to accelerate growth in Artificial Intelligence (AI) and data-driven research...
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James Mason @profjamesmason.bsky.social · 19/03/2025
Arguably the impact agenda driven by REF (which determines QR funding) is one of the more important levers for driving the benefits to the economy and the NHS that government desires.
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James Mason @profjamesmason.bsky.social · 02/03/2025
Applications are open now for the King's Prize Fellowship. These provide salary and up to £30k consumables for up to 24 months. @kingslsm.bsky.social is one of the best places in the world to start your independent biomedical or health-related research career. www.kcl.ac.uk/jobs/108525-...
kcl.ac.uk
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James Mason @profjamesmason.bsky.social · 25/02/2025
Substantial academic recruitment @kingscollegelondon.bsky.social in AI (up to 7 positions) and in physical sciences of life and/or engineering biology (up to 4 positions) www.kcl.ac.uk/jobs/interdi...
kcl.ac.uk
Academic opportunities in interdisciplinary sciences
We are delighted to announce exciting new opportunities to join our dynamic and interdisciplinary scientific community, as part of a major expansion of science across King’s.
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Nature Reviews Microbiology @natrevmicro.nature.com · 20/02/2025
New online! The role of bacterial metabolism in antimicrobial resistance
nature.com
The role of bacterial metabolism in antimicrobial resistance
Nature Reviews Microbiology, Published online: 20 February 2025; doi:10.1038/s41579-025-01155-0In this Review, Ahmad et al. examine how antibiotics influence bacterial metabolism and how metabolism, in turn, affects drug efficacy and the emergence and…
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 13/02/2025
𝗣𝗿𝗼𝘃𝗼𝗰𝗮𝘁𝗶𝘃𝗲: 𝗗𝗶𝗮𝗯𝗲𝘁𝗲𝘀 𝗳𝘂𝗲𝗹𝘀 𝗔𝗠𝗥 Staphylococcus aureus evolves antibiotic resistance rapidly in diabetic mice, as hyperglycemia aids the expansion and takeover of resistant mutants VISA strains have a large fitness defect in control mice but not in diabetic mice ➡️ www.science.org/doi/10.1126/...
science.org
Diabetes potentiates the emergence and expansion of antibiotic resistance
Diabetic infections are a reservoir for the emergence and proliferation of antibiotic resistance in Staphylococcus aureus.
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Craig MacLean @craigmaclean.bsky.social · 05/02/2025
Two new positions for group leaders working on #AMR at the Ineos Oxford Institute. my.corehr.com/pls/uoxrecru...
my.corehr.com
Job Details
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lorenzlab1.bsky.social @lorenzlab1.bsky.social · 29/01/2025
Our latest manuscript is now available in Biochemistry @acs.org (bit.ly/3Ct1PSm) In it we show that C-terminal amidation of an antimicrobial peptide increases its conformational flexibility, which improves membrane penetration, leads to faster bacterial killing & better selectivity for pathogens.
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King's Faculty of Life Sciences & Medicine @kingslsm.bsky.social · 29/01/2025
Tonight, we’re celebrating the Inaugural Lectures of Professor Maya Thanou and Professor Tomoki Arichi 🎓 Full details of the upcoming events in the series, along with recordings of previous lectures, can be found here: www.kcl.ac.uk/events/serie...
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King's Faculty of Life Sciences & Medicine @kingslsm.bsky.social · 23/01/2025
Congratulations to Prof Tomoki Arichi, Deanne Naula, Kaat De Backer and Dr Abigail Easter from our Faculty who were winners at the 2025 King's Engaged Research Awards last week 👏 Follow the link to read more about their awards and public and community engagement work ⬇️ www.kcl.ac.uk/news/winners...
kcl.ac.uk
Winners announced for the 2025 King's Engaged Research Awards
The King’s Engaged Research Awards ceremony brought together staff, students and community partners to celebrate public and community engagement with research at King’s.
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Reposted by James Mason
The Royal Society @royalsociety.org · 22/01/2025
The Royal Society's Newton International Fellowships are now open for applications. These fellowships are for non-UK early career scientists who wish to conduct research in the UK. Find out more, including how to apply: #RSGrants royalsociety.org/grants/newto...
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King's College London @kingscollegelondon.bsky.social · 21/01/2025
The King's Engaged Research Awards celebrate excellence in public and community engagement research, recognising King's staff and community partners for their achievements. Read about this year's winners and how they contributed to impactful research. ⬇️ www.kcl.ac.uk/news/winners...
kcl.ac.uk
Winners announced for the 2025 King's Engaged Research Awards
The King’s Engaged Research Awards ceremony brought together staff, students and community partners to celebrate public and community engagement with research at King’s.
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King's Faculty of Life Sciences & Medicine @kingslsm.bsky.social · 14/01/2025
Dr Caroline Copeland has been appointed to the Advisory Council on the Misuse of Drugs She will work with other members to advise the government on drug harms, such as substances that are being misused or could potentially cause significant health and social harms
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Nature Microbiology @natmicrobiol.nature.com · 14/01/2025
Could gut bacteria be the reason behind your sugar cravings? 🤤 Check out this new paper by Zhang et al. linking a gut microbe, a free fatty acid receptor, and sugar intake. www.nature.com/articles/s41...
nature.com
Free fatty acid receptor 4 modulates dietary sugar preference via the gut microbiota - Nature Microbiology
Bacteroides vulgatus, a gut bacterium, promotes GLP-1 secretion through its metabolite, pantothenate, inhibiting sugar preference in mice.
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Greg Gloor @ggloor.bsky.social · 06/01/2025
I would like to tell you about the journey to publish our vaginal meta-transcriptome paper microbiomejournal.biomedcentral.com…. I'm planning on doing this over the next few days as it's a little *complicated*.
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James Mason @profjamesmason.bsky.social · 30/12/2024
Nice work from Mahnoor and Barry, with the ever present support of our friends at UKHSA - "Construction of a drug sensitised Candida auris strain". Idea is to first find new classes of antifungals and then solve the efflux problem www.biorxiv.org/content/10.1...
biorxiv.org
Construction of a drug sensitised Candida auris strain
Candida auris is an emerging pathogenic fungus causing outbreaks of invasive disease in healthcare facilities worldwide with the majority of clinical isolates demonstrating intrinsic resistance to mul...
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Julie A. K. McDonald @julieakmcdonald.bsky.social · 13/12/2024
I’m excited to share a new preprint from our lab! We showed that vancomycin-resistant Enterococcus (VRE) colonise antibiotic-treated intestines by occupying distinct nutrient- and metabolite-defined intestinal niches. www.biorxiv.org/content/10.1...
biorxiv.org
Vancomycin-resistant Enterococcus colonise the antibiotic-treated intestine by occupying distinct nutrient- and metabolite-defined intestinal niches
Antibiotic treatment significantly disrupts the gut microbiome and promotes vancomycin-resistant Enterococcus (VRE) intestinal colonisation. These disruptions lead to the intestine acting as a reservo...
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