Sign in

Pierre Maisonneuve

@pierre-maisonneuve.bsky.social
177 followers 206 following 17 posts

Structural biologist in human signaling and pseudokinase aficionados. Group leader IECB, CBMN, CNRS Researcher, University of Bordeaux

PostsRepliesMedia
Pierre Maisonneuve @pierre-maisonneuve.bsky.social · 22/09/2026
⏰ Reminder: French Kinase Conference, Nov 9–10, 2026, @iecb.bsky.social Bordeaux. fkc2026.sciencesconf.org Registration from just €80 thanks to our sponsors' support, so more students can attend & present their work (Oral & Poster)! 📅 Abstracts: Oct 2 · Registration: Oct 16 🔗
123
Pierre Maisonneuve @pierre-maisonneuve.bsky.social · 03/09/2026
🧬 Announcing the French Kinase Conference - 1st edition! Nov 9–10, 2026, @iecb.bsky.social We aim to bring together the French community of biologists, structural biologists, and medicinal chemists working on protein kinases. 🔗 fkc2026.sciencesconf.org #Kinases #cellsignaling #DrugDiscovery
143
Reposted by Pierre Maisonneuve
Dr. Natalia Riobo-Del Galdo @thehedgehoglab.bsky.social · 10/11/2025
We have a fully funded studentship to start your PhD in October 2026! Work with me, Elton Zeqiraj and Joe Cockburn to find new ways to treat diseases with high levels of Hedgehog signalling. Fantastic training in cell and structural biology, genomic screening and biochemistry at the Uni of Leeds!
findaphd.com
Stopping GLI transcription factors in their tracks: identifying regulators of proteolysis as therapeutic targets. at University of Leeds on FindAPhD.com
PhD Project - Stopping GLI transcription factors in their tracks: identifying regulators of proteolysis as therapeutic targets. at University of Leeds, listed on FindAPhD.com
174
Reposted by Pierre Maisonneuve
Oli Clarke @olibclarke.bsky.social · 13/09/2025
This one is a bit of a departure from the usual and definitely a work in progress! We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below. Read on for details... 1/x
2026782
Reposted by Pierre Maisonneuve
Université de Bordeaux @univbordeaux.bsky.social · 04/09/2025
🔬 Braf : le verrou moléculaire que les cellules cancéreuses peuvent forcer - Une équipe internationale, dont des scientifiques bordelais du CBMN*, explorent une piste prometteuse pour entraver ces cellules cancéreuses :
inc.cnrs.fr
Braf : le verrou moléculaire que les cellules cancéreuses peuvent forcer | CNRS Chimie
Des scientifiques ont percé le secret de mutations génétiques communes à de nombreux cancers qui activent de manière anarchique une protéine-clé de la d
122
Reposted by Pierre Maisonneuve
James Murphy @pseudokinase.bsky.social · 18/08/2025
Flying start to the #iubmbkinases meeting in beautiful Queenstown, NZ. Jubilee Award from IUBMB to Kevan Shokat yesterday, and a kinase masterclass from Susan Taylor this morning
0145
Reposted by Pierre Maisonneuve
Science Magazine @science.org · 03/07/2025
New research in Science greatly expands the potential target scope of molecular glues and should stimulate the development of new small molecules that can selectively target therapeutically relevant proteins for degradation. Learn more in this week's issue: scim.ag/44uRorm
This illustration shows the interface of the kinase NEK7 (light blue) and the E3 ubiquitin ligase substrate receptor cereblon (teal). The interaction is facilitated by the small molecule MRT-3486 (orange).
05317
Pierre Maisonneuve @pierre-maisonneuve.bsky.social · 19/06/2025
🚨 Fully funded PhD position in plant & structural biology! Join the @eliastahl.bsky.social lab in collaboration with our team. Exciting project on protein structure/function in plants 🌱. Contact us for details! #PlantBiology #StructuralBiology #PhDposition @iecb.bsky.social
063
Reposted by Pierre Maisonneuve
Jane Dudley @janedudley.bsky.social · 06/06/2025
Fascinating and diverse programme of talks at the joint Autophagy UK and @ukproteostasis.bsky.social meeting in Dundee this week! & super happy to have the chance share our #pseudoligase work 📣
0144
Pierre Maisonneuve @pierre-maisonneuve.bsky.social · 30/05/2025
🎉 New paper out in Science! In collaboration with Marc Therrien’s lab, we show how oncogenic BRAF mutants adopt a pre-active conformation, escaping auto-inhibition and driving RAS–ERK pathway activation in cancer. Proud to have contributed! #IRIC #CBMN @iecb.bsky.social @univbordeaux.bsky.social
science.org
BRAF oncogenic mutants evade autoinhibition through a common mechanism
Uncontrolled activation of the rat sarcoma (RAS)–extracellular signal–regulated kinase (ERK) pathway drives tumor growth, often because of oncogenic BRAF mutations. BRAF regulation, involving monomeri...
1206
Reposted by Pierre Maisonneuve
Peter Mace @petermace.bsky.social · 23/05/2025
With less than a month to submit abstracts for the @iubmb.bsky.social Focussed Meeting on (pseudo)Kinases in stunning Queenstown, we are delighted to announce travel scholarships for selected ECRs thanks to @biologists.bsky.social and the Maurice and Phyllis Trust! www.ivvy.com.au/event/IUBMB25/
156
Reposted by Pierre Maisonneuve
IECB Bordeaux @iecb.bsky.social · 14/04/2025
We are recruiting 🤩🤩🤩!!! If you are looking to establish ylur lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, apply!!!
02022
Reposted by Pierre Maisonneuve
Yann Fichou @fichoulab.bsky.social · 26/03/2025
A few more days to apply for postdoctoral positions in my group. We investigate : - tau amyloid formation at a molecular level - tau LLPS - tau-spliceosome interaction in tauopathies. More info here : www.fichou-lab.cnrs.fr/en/home
fichou-lab.cnrs.fr
Home - Yann Fichou
The Fichou Lab focuses on the molecular mechanisms underlying neurodegenerative diseases.
01210
Reposted by Pierre Maisonneuve
Lori Passmore @lapassmore.bsky.social · 22/02/2025
Reminder - still one month to apply to be a tenure track group leader at MRC LMB. Please do reach out for any information.
02532
Pierre Maisonneuve @pierre-maisonneuve.bsky.social · 14/02/2025
(1/4) 🚀 PhD Fellowship Opportunity @iecb.bsky.social @univbordeaux.bsky.social University of Bordeaux! Looking for talented international Master’s graduates to apply for a PhD fellowship via the UB PhD Scholarship. Two exciting projects in kinase biology & nanobody therapeutics! ⬇️ Please Repost
145
Reposted by Pierre Maisonneuve
IECB Bordeaux @iecb.bsky.social · 28/01/2025
Join us next week on Friday the 7th, at 11 am, in our IECB amphitheater to learn a whole lot on the design and applications of enzyme cascades for organic synthesis 🤓🧪👩‍🔬⚗️! Guest speaker Prof. Sabine Flitsch from the University of Manchester 🤩!!! www.iecb.u-bordeaux.fr/evenements/i...
086
Pierre Maisonneuve @pierre-maisonneuve.bsky.social · 29/01/2025
Looking forward to be there! The list of speakers is impressive. So proud to be part of it.
150