iiinova — where your digital self keeps evolving

Jane Dudley @janedudley.bsky.social · 23/03/2026

So delighted to have been part of this fantastic collaboration spearheaded by Ngee Kiat 'Jake' Chua (蔡毅杰) and Rebecca Feltham! Congratulations on bringing together so many experts in the field to make such an important resource 🎉 it has been a pleasure! www.sciencedirect.com/science/arti...

sciencedirect.com

The E3-ome gene-centric compendium reveals the human E3 ligase landscape

To define and systematically characterize the human E3 ubiquitin ligase (E3) landscape, we generated the E3-ome, a compendium of E3s encoded by the hu…

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Jane Dudley @janedudley.bsky.social · 10/07/2025

Heatwave in London as seen from the Crick’s roof terrace at lunchtime ☀️

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Jane Dudley @janedudley.bsky.social · 17/06/2025

Do you want to hear more about ubiquitin? Are you free on Friday 14:00 BST? If so, why not join the Biochemical Society early career researcher webinar series where my fellow UCL alumnus Michele Frison and I will be presenting! 💻 💡 Registration: register.gotowebinar.com/register/821...

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Jane Dudley @janedudley.bsky.social · 06/06/2025

Fascinating and diverse programme of talks at the joint Autophagy UK and @ukproteostasis.bsky.social meeting in Dundee this week! & super happy to have the chance share our #pseudoligase work 📣

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Reposted by Jane Dudley

Elton Zeqiraj @zeqiraj.bsky.social · 17/03/2025

Excited to report our latest research on new “molecular glues” that specifically lock the BRCC36 isopeptidase complex (BRISC) in an autoinhibited state and reduce interferon signalling. This first-of-its-kind approach could reshape how we target large deubiquitylase (DUB) complexes. rdcu.be/edRwF

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Reposted by Jane Dudley

Yogesh Kulathu @kulathu.bsky.social · 16/02/2025

Autophagy UK & Proteostasis UK joint meeting -June 3-5. Exploring the lifecycle of cellular components from synthesis to degradation. Going to be a great meeting and we look forward to welcoming you to Dundee! Exciting lineup of speakers and opportunities for ECRs Register here: tinyurl.com/mr3p49f9

tinyurl.com

Joint 2025 Autophagy UK and Proteostasis UK conference | University of Dundee, UK

Welcome to the 2025 joint “Autophagy UK and Proteostasis UK” conference!

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Jane Dudley @janedudley.bsky.social · 20/01/2025

Really enjoying kicking off the week with this new, excellently-written review on #ubiquitin from a structural perspective - so useful to step back every now and again and get an eagle's eye view on the field! www.cell.com/molecular-ce...

cell.com

Ubiquitin—A structural perspective

Ubiquitin is a cellular modification that comes in many forms. In this review, Agrata and Komander analyze the 240 available PDB structures of ubiquitin and polyubiquitin, alongside ensemble and molec...

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Jane Dudley @janedudley.bsky.social · 13/12/2024

Mixing a leaving party with our Christmas party; house music with high res imaging… #Crickmas @crick.ac.uk

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Jane Dudley @janedudley.bsky.social · 06/12/2024

Christmas is looking very jolly here at the Crick! @thecrick.bsky.social 🎄✨ takes the edge off early starts with such short daylight hours…

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Reposted by Jane Dudley

University of Oxford @ox.ac.uk · 02/12/2024

CONFIRMED: Oxford University Press select 'brain rot' as the 2024 Oxford Word of the Year 🧠📱 #OxfordWOTY

Image showing a dictionary-style entry for the term "brain rot," defined as an intellectual deterioration viewed as a result of overconsumption of trivial or unchallenging online content, potentially leading to further cognitive decline. The word is highlighted in bold with a graphic of a brain with ice cream elements above it.

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