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Daniel Castro

@flanbrain.bsky.social
1.2K followers 195 following 9 posts

Assistant Professor at Washington University in St. Louis. We study endogenous opioids in affect, motivation, and metabolism. I love food and puppies.

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Reposted by Daniel Castro
Zach Pennington @zachtpennington.bsky.social · 20h
I'm SO excited to have this out in the world!!!! Check out our latest work on the contribution of the anterior hypothalamic nucleus to stress sensitivity and valence processing.
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Daniel Castro @flanbrain.bsky.social · 03/08/2026
Another one! Congrats to Javi Kelly Cuenca, a graduate student in our lab, for receiving the NoA for his NRSA F31! His project will investigate how opioids in the cortex regulate reward and motivation!
static.klipy.com
Adore Delano Says Party!
ALT: Adore Delano Says Party!
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Daniel Castro @flanbrain.bsky.social · 21/07/2026
Fresh from the Castro Lab! We characterize how mu opioid receptors on pancreatic alpha cells regulate ingestive phenotypes. Surprise! Mu can act both inside and outside the brain😱 Congrats to our technician Diego De Gregorio! @ssibsociety.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Pancreatic mu opioid receptors regulate metabolism and ingestive behaviors
The mu opioid receptor system has long been recognized for its role in regulating ingestive behaviors and food palatability. However, beyond their rob…
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Daniel Castro @flanbrain.bsky.social · 26/06/2026
My grad student Javier Kelly Cuenca will be there!! If you’ve got an interest in cortical opioids, then he is someone you will definitely want to meet!
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Reposted by Daniel Castro
GRC Frontal Cortex @grc-frontal-cortex.bsky.social · 14/04/2026
Frontal Cortex Peeps: The full program for the 2026 GRC Frontal Cortex is now available! Applications are due July 12, 2026 - don't delay! Spots are starting to fill up! Check out the complete program and register here --> www.grc.org/frontal-cort...
grc.org
2026 Frontal Cortex Conference GRC
The 2026 Gordon Research Conference on Frontal Cortex will be held in Holderness, New Hampshire. Apply today to reserve your spot.
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Daniel Castro @flanbrain.bsky.social · 01/06/2026
First Castro Lab paper, brought to you by the hard work of Dr. Kathryn Braden @katybraden.bsky.social In this manuscript we investigate the role of endogenous enkephalin or dorsal raphe nucleus. We find that it is incredibly important for buffering negative affect 😱 www.nature.com/articles/s41...
nature.com
Dorsal raphe nucleus enkephalin peptide modulates behavioral preference - Neuropsychopharmacology
Neuropsychopharmacology - Dorsal raphe nucleus enkephalin peptide modulates behavioral preference
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Reposted by Daniel Castro
NPP-Digital Psychiatry and Neuroscience (DPN) @dpn-journal.bsky.social · 28/08/2025
"Neuropsychopharmacology in the era of artificial intelligence and biomolecule prediction software" @flanbrain.bsky.social & colleagues discuss how machine learning algorithms such as AlphaFold (which predict 3D protein structures) can facilitate drug discovery www.nature.com/articles/s44...
nature.com
Neuropsychopharmacology in the era of artificial intelligence and biomolecule prediction software - NPP—Digital Psychiatry and Neuroscience
This article explores how artificial intelligence (AI) is changing the way we discover new treatments for brain and mental health disorders. Instead of relying solely on slow and complex lab work, sci...
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Reposted by Daniel Castro
NPP-Digital Psychiatry and Neuroscience (DPN) @dpn-journal.bsky.social · 30/06/2025
🆕 perspective from @flanbrain.bsky.social et al on how machine learning algorithms such as AlphaFold, which predict 3D protein structures, can facilitate drug discovery in neuropsychopharmacology. Check it out!! www.nature.com/artic...
nature.com
Neuropsychopharmacology in the era of artificial intelligence and biomolecule prediction software
NPP—Digital Psychiatry and Neuroscience - Neuropsychopharmacology in the era of artificial intelligence and biomolecule prediction software
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Daniel Castro @flanbrain.bsky.social · 29/04/2025
@usasp.bsky.social here we are! Excited for the coming days and getting to see everyone in Chicago!! 🤩💃🏻💃🏻🕺🏻🕺🏻 don’t forget to see @katybraden.bsky.social poster tomorrow morning!! It has motivation, CRISPR, opioids, and pain! 😱😱👀👀😳😳🫢
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Daniel Castro @flanbrain.bsky.social · 09/04/2025
It finally happened, the Castro lab's first paper! Congrats to @katybraden.bsky.social !! In this review we examine what we know, and more importantly, what we DON'T know about neuropeptides in the dorsal raphe/ventromedial PAG. Here we go! www.frontiersin.org/journals/beh...
media.tenor.com
a drag queen wearing a blue dress with the word iconic on the front
ALT: a drag queen wearing a blue dress with the word iconic on the front
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Dustin Green @dustinpgreen.bsky.social · 09/01/2025
Excited to host @flanbrain.bsky.social !
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Carrie Ferrario @cferrario.bsky.social · 10/12/2024
#acnp2024 open position at UM Pharmacology. Happy to answer questions!
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Reposted by Daniel Castro
Kathryn Braden, PhD @katybraden.bsky.social · 12/12/2024
To cap off an incredible week at #ACNP2024 I woke up to the Notice of Award for my NRSA!!! I am so grateful for this opportunity to grow and develop more as a scientist. Thank you @flanbrain.bsky.social for your support and incredible mentorship! I’m so excited for this next chapter of my career!
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Sean Piantadosi @piantadosisean.bsky.social · 11/12/2024
If you are still at #ACNP2024 and are interested in the locus coeruleus and/or the amygdala, please stop by my poster from the @mbruchas lab examining how both nodes of this circuit mediate stress-induced anxiety-like behavior tonight (W169)!
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Reposted by Daniel Castro
Neuropsychopharmacology @npp-journal.bsky.social · 09/12/2024
Hey #ACNP2024 - we seem to have quite a few stellar early career researchers on (or about to be on) the job market If you know of any current/upcoming openings, maybe you can drop them here so you can recruit these all-stars 🤩 👇
media.tenor.com
a looney tunes looking for a job poster with wile e coyote looking through binoculars
ALT: a looney tunes looking for a job poster with wile e coyote looking through binoculars
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Daniel Castro @flanbrain.bsky.social · 07/12/2024
Headed to @acnporg.bsky.social come see our panel on opioids and depression Monday morning, and DEFINITELY stop by our lab’s postdoc @katybraden.bsky.social poster to learn more!! 🤩🤩💃🏻💃🏻👯‍♂️👯‍♂️👯‍♂️
media.tenor.com
a woman wearing glasses and a black top says you have a lot to learn
ALT: a woman wearing glasses and a black top says you have a lot to learn
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