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Sachin Sethi

@sethisachin.bsky.social
61 followers 62 following 2 posts

Postdoc in Maimon Lab at Rockefeller University

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Reposted by Sachin Sethi
Kit D. Longden @theflyside.bsky.social · 21/08/2026
Very nice work setting out efference copy circuitry in fly visual system from @fleyes.bsky.social lab 👏 www.biorxiv.org/content/10.6...
biorxiv.org
Vectorial efference copy and visuomotor transformation through gap junctions
Distinguishing visual input generated by active eye movements from input due to external events is a fundamental challenge for visual processing. Here, we uncover a remarkably simple solution to this ...
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Reposted by Sachin Sethi
Jacopo Razzauti @jacoporazzauti.bsky.social · 16/07/2026
FERAL 1.0 is out! Just to remind you: FERAL is an open-source toolkit for supervised animal behaviour segmentation directly from videos with no pose estimation needed. We made it much easier to install and run FERAL First, to install FERAL: pip install feral www.biorxiv.org/content/10.1... 🧵
biorxiv.org
FERAL: A Supervised Video-Understanding System for Direct Video-to-Behavior Mapping
Quantifying animal behavior often requires segmenting continuous actions into discrete, interpretable states, yet most automated pipelines infer actions from keypoint dynamics and are limited by keypo...
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Reposted by Sachin Sethi
Adrian Duszkiewicz @adrian-du.bsky.social · 15/07/2026
Functional Logic of a Cognitive Brain System for Navigation A fascinating review of the Drosophila head-direction system by Gaby Maimon and Larry Abbott #neuroskyence #compneuro
annualreviews.org
Functional Logic of a Cognitive Brain System for Navigation
It is unusual for cognitive neuroscientists to reach consensus around which computations a brain region implements, what algorithms are used to achieve those computations and how the algorithms are im...
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Reposted by Sachin Sethi
Sofia Avritzer @sofiavritzer.bsky.social · 10/03/2026
Happy to share my first story for @nature.com, looking at an aspect of science that doesn’t get discussed enough: retractions that happen because scientists discover honest mistakes in their work. I spoke with researchers who chose to self-retract about what helped them get through the process.
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Reposted by Sachin Sethi
Lukas Groschner @lukasgroschner.bsky.social · 14/02/2026
🚨 We are #hiring a PhD Student to study cerebellum-like circuits in #Drosophila. Please spread the word! www.groschner-lab.org/join #Neuroscience #PhD
Fluorescent neurons on black background. We're hiring! PhD Student
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Reposted by Sachin Sethi
Sofia Avritzer @sofiavritzer.bsky.social · 29/01/2026
So excited to share a story I wrote for @snexplores.bsky.social on how some animals make themselves (almost) invisible - and why humans can't do the same! My last piece written as a @aaasmassmedia.bsky.social, and probably the one I had the most fun working on. www.snexplores.org/article/how-...
snexplores.org
Is it possible to be invisible?
Fiction is full of characters with the power to vanish. But some animals have real-life ways to become nearly invisible.
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Sachin Sethi @sethisachin.bsky.social · 06/01/2026
www.cell.com/cell/fulltex... We had a lot of fun working on this project (led by Itzel Ishida, not on bluesky). Some interesting highlights from the paper -
cell.com
Neuronal calcium spikes enable vector inversion in the Drosophila brain
In the fly central complex, PFNa neurons switch from firing classical sodium spikes when depolarized to firing non-canonical T-type calcium spikes when hyperpolarized. This bidirectional spiking allow...
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Reposted by Sachin Sethi
Hannah Haberkern @hannah-haberkern.bsky.social · 23/12/2025
📢 Join us, the Haberkern lab, @uni-wuerzburg.de for a postdoc studying neural circuit mechanisms of navigation. You’ll spearheading neurophysiology experiments on our brand new 2P! ⏳ Apply by 28th February 2026 Details: www.haberkernlab.de/docs/ENPostd... #neuroscience #academicjobs #postdoc
On the left, the image shows a schematic of a fly head, ring neurons and EPG neurons together with some calcium imaging frames. On the right is a photo of a fly on a ball in virtual reality and another schematic of a VR system.
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Reposted by Sachin Sethi
Yvette Fisher @yvetteefisher.bsky.social · 15/12/2025
*First preprint from our lab* !!!!! How does the brain learn to anchor its internal sense of direction to the outside world? 🧭 led by Mark Plitt @markplitt.bsky.social & Dan Turner-Evans, w/ Vivek Jayaraman: “Octopamine instructs head direction plasticity” www.biorxiv.org/content/10.6... Thread ⬇️
Schematic of how ER-EPG plasticity enables the bump of activity in EPGs to accurately track visual cues. As a fly makes a counter-clockwise turn (top to bottom) it will view visual cues (e.g. the sun) from a new angle and the EPG activity bump (red) will swing clockwise around the network by integrating self motion signals with these visual inputs. When the fly faces a different angle, distinct visual ER neurons are active. Plasticity forms a trough of weak synapses (large circles - strong synapses, small circles - weak synapses) that allow ER neurons with distinct visual tuning to move the EPG bump via disinhibition.
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